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The map label for this gene is moaB [H]

Identifier: 197118656

GI number: 197118656

Start: 2646108

End: 2646605

Strand: Direct

Name: moaB [H]

Synonym: Gbem_2275

Alternate gene names: 197118656

Gene position: 2646108-2646605 (Clockwise)

Preceding gene: 197118655

Following gene: 197118657

Centisome position: 57.34

GC content: 65.66

Gene sequence:

>498_bases
ATGCGAGCAGCGATATTGACCTTAAGCGACCGTTGCTCCACCGGCGAGCGTGCGGACGGCAGCGGCCCCGCCCTGAGAAG
CTGGTTGGAAGAGCACGGGGTGACCGTCACCTGCACCGAAGTGATCCCGGACGAGGCGTCCCTCATCTCGGAAAAGCTGG
CGGCCTGGTCCGATAGCGGAAGCTTCGACCTCATCCTCACCACCGGTGGGACCGGCGTCTCCCCGCGCGACGTGACGCCA
GAGGCGACCGAACGGGTGGTCGACCGGGTGCTCCCCGGCTTCGGCGAGGTGATGCGCGCGGAGAGTCTGAAAAAAACCCC
GCACGCCATCATCTCCCGCGCCATCGCCGGGATCAGGAAAAACACCCTGATCATCAACCTCCCCGGGAGCCCCAAAGGGG
CGACGGAAAACATCAGTTTCGTCTGGGCCGCCGTTCCCCACGCCGTCGCCAAGCTGCAGGGAGACCCGGAGGAATGCGGC
ACGCCGCTATCCAAGTGA

Upstream 100 bases:

>100_bases
AGGGGATCGTGATCTCCGACGTGAAGCTCCACTACAAGGAAGGCGGCAAGAGCGGCGTCTTCAAAAGAGAAGCGTAAGGA
TTTCCAAAGGAGATTTTCCC

Downstream 100 bases:

>100_bases
TGCATATCCGTACCCTTTTTTATTGACCGATCCGACCTGCTGGGTTATACAACTAACACGGTTTGAAAATTTAATACGGA
GGGATCATCATGCCGTTGGT

Product: molybdopterin adenylyltransferase MoaB

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRAAILTLSDRCSTGERADGSGPALRSWLEEHGVTVTCTEVIPDEASLISEKLAAWSDSGSFDLILTTGGTGVSPRDVTP
EATERVVDRVLPGFGEVMRAESLKKTPHAIISRAIAGIRKNTLIINLPGSPKGATENISFVWAAVPHAVAKLQGDPEECG
TPLSK

Sequences:

>Translated_165_residues
MRAAILTLSDRCSTGERADGSGPALRSWLEEHGVTVTCTEVIPDEASLISEKLAAWSDSGSFDLILTTGGTGVSPRDVTP
EATERVVDRVLPGFGEVMRAESLKKTPHAIISRAIAGIRKNTLIINLPGSPKGATENISFVWAAVPHAVAKLQGDPEECG
TPLSK
>Mature_165_residues
MRAAILTLSDRCSTGERADGSGPALRSWLEEHGVTVTCTEVIPDEASLISEKLAAWSDSGSFDLILTTGGTGVSPRDVTP
EATERVVDRVLPGFGEVMRAESLKKTPHAIISRAIAGIRKNTLIINLPGSPKGATENISFVWAAVPHAVAKLQGDPEECG
TPLSK

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=156, Percent_Identity=44.8717948717949, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI10880983, Length=156, Percent_Identity=44.8717948717949, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1786190, Length=168, Percent_Identity=42.8571428571429, Blast_Score=123, Evalue=5e-30,
Organism=Escherichia coli, GI1787000, Length=141, Percent_Identity=39.7163120567376, Blast_Score=85, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564954, Length=141, Percent_Identity=46.8085106382979, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI17136978, Length=152, Percent_Identity=43.421052631579, Blast_Score=123, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24638841, Length=152, Percent_Identity=43.421052631579, Blast_Score=123, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 17403; Mature: 17403

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAILTLSDRCSTGERADGSGPALRSWLEEHGVTVTCTEVIPDEASLISEKLAAWSDSG
CCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCC
SFDLILTTGGTGVSPRDVTPEATERVVDRVLPGFGEVMRAESLKKTPHAIISRAIAGIRK
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCC
NTLIINLPGSPKGATENISFVWAAVPHAVAKLQGDPEECGTPLSK
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MRAAILTLSDRCSTGERADGSGPALRSWLEEHGVTVTCTEVIPDEASLISEKLAAWSDSG
CCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCC
SFDLILTTGGTGVSPRDVTPEATERVVDRVLPGFGEVMRAESLKKTPHAIISRAIAGIRK
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCC
NTLIINLPGSPKGATENISFVWAAVPHAVAKLQGDPEECGTPLSK
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]