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The map label for this gene is namA [H]

Identifier: 197118516

GI number: 197118516

Start: 2482373

End: 2483434

Strand: Direct

Name: namA [H]

Synonym: Gbem_2134

Alternate gene names: 197118516

Gene position: 2482373-2483434 (Clockwise)

Preceding gene: 197118515

Following gene: 197118517

Centisome position: 53.79

GC content: 66.67

Gene sequence:

>1062_bases
ATGAGCATGCTCTTTACCCCGCTGCAGCTGCGGGAGCTGACCTTCAAAAACCGCATCTTCGTCTCCCCCATGTGCCAGTA
TTCGAGTAAAGACGGGATGCCGACGGATTGGCACCTGGTACATCTGGGAAGCCGGGCGGTCGGCGGCGCCGGGCTCGTCA
TGGTCGAAGCGACGGCGGTTTCCCAGCAGGGGCGCATCTCGCCGGACGACTCCGGCATCTGGAGCGCGGACCACGCCCGG
GCCTTTGCCCCCATCGCCCGCTTCATCAAGGAACAGGGTGCGGTGCCGGGAATCCAGCTGGCCCATGCCGGGCGCAAGGC
TTCCACCGACCTTCCCTGGAAAGGGAGCGGCCCGGTGGATGCGAACCACCGCGGCTGGCAGACCATCGCCCCCAGCCCGG
TTCCGTTTGCCGGAAACTTCCCCTCTCCCAGGGAGGCAACCGTCCAGGACCTGGAGATCATCCTGGGGCAGTTCGCCTCC
GCCGCGCGCCGCAGTGCCGAAGCCGGATTCGAGGTGGTGGAGATTCACATGGCGCACGGCTACCTGCTGCACGAGTTCCT
CTCACCGCTGGCGAACCTGCGCGCGGATGATTTCGGAGGGTCGCTGGAGAACCGTTGCCGCTTCCCGTTGCGGGTGGCGA
AGGCTGTGCGCGAGATCTGGCCCGAGCATCTTCCGGTGTTCGTGAGGGTCTCGGCATCGGACTGGATGGAGGGGGGGTGG
GATCTGGAGCAGACGGTGGAACTGGTACGGAGGCTCAAGGCGATCGGAGTCGACCTGATCGACTGCTCCAGCGGCGGACT
GGTCCCCGAGGCTGCGCCCCCTTTCGGCCCCGGCTTCCAGACCCCCTTCGCCACCGAGATCAGGAAACAGGCAGGCATCG
CCACCGGTGCCGTCGGTTTCATCACCGCCCCGGCGCAAGCCGAGCATATCGTGGCGACGGGGCTTGCCGATGCGGTGTTC
CTGGCGCGCGAGATGCTGAGGGACCCGTACTGGCCGCTGCACGCGGCCAATGCGCTGCAGGTCGACCCCGCCTGGCCCAG
CCAGTACGAAAGGGCTAAATGA

Upstream 100 bases:

>100_bases
AGCTTTAACTGCGCCTTTGCATTGACCTTCCCCTGCCGGTTGATAAGCTGCCGCAGGGGTTGGGGCTTGCCCCGCGATTC
TTTTATAGGGAGGGTAACCA

Downstream 100 bases:

>100_bases
AGCTGTGTGTCGTTGGCCGCAACCAGCGTGACGTCACACTGGCACCTTCATTGAGTGACAAATGCTTGTCCATGGTCGAA
CAGGCTGTACATTCTGGCAG

Product: NADPH-dependent enal/enone/nitroreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSMLFTPLQLRELTFKNRIFVSPMCQYSSKDGMPTDWHLVHLGSRAVGGAGLVMVEATAVSQQGRISPDDSGIWSADHAR
AFAPIARFIKEQGAVPGIQLAHAGRKASTDLPWKGSGPVDANHRGWQTIAPSPVPFAGNFPSPREATVQDLEIILGQFAS
AARRSAEAGFEVVEIHMAHGYLLHEFLSPLANLRADDFGGSLENRCRFPLRVAKAVREIWPEHLPVFVRVSASDWMEGGW
DLEQTVELVRRLKAIGVDLIDCSSGGLVPEAAPPFGPGFQTPFATEIRKQAGIATGAVGFITAPAQAEHIVATGLADAVF
LAREMLRDPYWPLHAANALQVDPAWPSQYERAK

Sequences:

>Translated_353_residues
MSMLFTPLQLRELTFKNRIFVSPMCQYSSKDGMPTDWHLVHLGSRAVGGAGLVMVEATAVSQQGRISPDDSGIWSADHAR
AFAPIARFIKEQGAVPGIQLAHAGRKASTDLPWKGSGPVDANHRGWQTIAPSPVPFAGNFPSPREATVQDLEIILGQFAS
AARRSAEAGFEVVEIHMAHGYLLHEFLSPLANLRADDFGGSLENRCRFPLRVAKAVREIWPEHLPVFVRVSASDWMEGGW
DLEQTVELVRRLKAIGVDLIDCSSGGLVPEAAPPFGPGFQTPFATEIRKQAGIATGAVGFITAPAQAEHIVATGLADAVF
LAREMLRDPYWPLHAANALQVDPAWPSQYERAK
>Mature_352_residues
SMLFTPLQLRELTFKNRIFVSPMCQYSSKDGMPTDWHLVHLGSRAVGGAGLVMVEATAVSQQGRISPDDSGIWSADHARA
FAPIARFIKEQGAVPGIQLAHAGRKASTDLPWKGSGPVDANHRGWQTIAPSPVPFAGNFPSPREATVQDLEIILGQFASA
ARRSAEAGFEVVEIHMAHGYLLHEFLSPLANLRADDFGGSLENRCRFPLRVAKAVREIWPEHLPVFVRVSASDWMEGGWD
LEQTVELVRRLKAIGVDLIDCSSGGLVPEAAPPFGPGFQTPFATEIRKQAGIATGAVGFITAPAQAEHIVATGLADAVFL
AREMLRDPYWPLHAANALQVDPAWPSQYERAK

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=337, Percent_Identity=30.5637982195846, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789463, Length=338, Percent_Identity=26.6272189349112, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17566914, Length=359, Percent_Identity=29.2479108635098, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17559802, Length=323, Percent_Identity=28.7925696594427, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI72001454, Length=324, Percent_Identity=27.1604938271605, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559804, Length=268, Percent_Identity=27.2388059701493, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564188, Length=245, Percent_Identity=26.9387755102041, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17540738, Length=268, Percent_Identity=26.1194029850746, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=320, Percent_Identity=25.625, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=228, Percent_Identity=29.8245614035088, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325086, Length=229, Percent_Identity=28.82096069869, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 38343; Mature: 38212

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMLFTPLQLRELTFKNRIFVSPMCQYSSKDGMPTDWHLVHLGSRAVGGAGLVMVEATAV
CCCCCCHHHHHHHHHCCEEEECHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEHH
SQQGRISPDDSGIWSADHARAFAPIARFIKEQGAVPGIQLAHAGRKASTDLPWKGSGPVD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCC
ANHRGWQTIAPSPVPFAGNFPSPREATVQDLEIILGQFASAARRSAEAGFEVVEIHMAHG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHH
YLLHEFLSPLANLRADDFGGSLENRCRFPLRVAKAVREIWPEHLPVFVRVSASDWMEGGW
HHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCHHHCCEEEEECCHHHCCCCC
DLEQTVELVRRLKAIGVDLIDCSSGGLVPEAAPPFGPGFQTPFATEIRKQAGIATGAVGF
CHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHE
ITAPAQAEHIVATGLADAVFLAREMLRDPYWPLHAANALQVDPAWPSQYERAK
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHCCCC
>Mature Secondary Structure 
SMLFTPLQLRELTFKNRIFVSPMCQYSSKDGMPTDWHLVHLGSRAVGGAGLVMVEATAV
CCCCCHHHHHHHHHCCEEEECHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEHH
SQQGRISPDDSGIWSADHARAFAPIARFIKEQGAVPGIQLAHAGRKASTDLPWKGSGPVD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCC
ANHRGWQTIAPSPVPFAGNFPSPREATVQDLEIILGQFASAARRSAEAGFEVVEIHMAHG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHH
YLLHEFLSPLANLRADDFGGSLENRCRFPLRVAKAVREIWPEHLPVFVRVSASDWMEGGW
HHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCHHHCCEEEEECCHHHCCCCC
DLEQTVELVRRLKAIGVDLIDCSSGGLVPEAAPPFGPGFQTPFATEIRKQAGIATGAVGF
CHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHE
ITAPAQAEHIVATGLADAVFLAREMLRDPYWPLHAANALQVDPAWPSQYERAK
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA