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The map label for this gene is modB-1 [H]

Identifier: 197118356

GI number: 197118356

Start: 2278336

End: 2279019

Strand: Direct

Name: modB-1 [H]

Synonym: Gbem_1974

Alternate gene names: 197118356

Gene position: 2278336-2279019 (Clockwise)

Preceding gene: 197118355

Following gene: 197118357

Centisome position: 49.37

GC content: 64.33

Gene sequence:

>684_bases
ATGCCACTTCTGACCAGCGCCGATCATGATGCCATAGCCCTCTCCATCAGGGTTGCCCTGGCGGCCACGCTGCTGAGCAT
CCCCTTTGGCTTCGCCTACGCCTATCTCATGACCTTTTGCCGGTTCCGCGGCAAGGTGCTGCTCGAAGTCTTGGTCAACC
TCCCTCTGACGCTTCCTCCCGTTGTGATGGGGTACCTGCTGCTGCTCGCACTCGGGAAAAACGGGTGGCTCTCCTTTTTG
CTCGAACCGCTTGGTGTGCGGTTGATCTTCACCTGGAAAGCGGCTGTGCTGGCCTCGGCCGTGGTGGGATTTCCCCTACT
GGTACGCTCGATCAGGATCGCCATGGAAGGGATCGACAGCCGGCTCCTCCAGGCCTCCCGTACCCTGGGGGCGACCAGGC
TGGACTCGCTCTTCTCGGTGGTGCTGCCGCTTTCCAAGGCGGGGGTGGTGGCCGGTTCCTCGCTGATGTTCGCTCGCAGC
CTGGGCGAGTTCGGCGCCACCGTGATCGTGGCCGGCAACATCCCCGGCGCCACCCAGACCATCCCGCTGGCCATCTACGA
CTACGCCGGCTCCCCGGGTGCAGAGGGCGCCGCACTCTCGCTCTGCGTGGTGGCCATTGCCATATCCGTTCTGGTGCTGC
TGTTCCACGAGGCGTTGGCCCGGAAGCTGGCTGGGAGGGACTGA

Upstream 100 bases:

>100_bases
CAGGCGCAGTTGCAGCCTCCGGCCGCCTCTGGAATGGAACCTGCTTAGGAAGAAGTCGCACTCACGACCGCTGCCCTTCC
GGCGGCGGCAAGGAGGATGA

Downstream 100 bases:

>100_bases
GATGGAACTGCGCATAAAAGCCGGCAAGGGGTTCGGAGGGGCTTTCAACCTGGAGACGGACCTAGTGGTATCCGGGGACA
GGGTGGGTGTGTTCGGCGCG

Product: molybdate ABC transporter membrane protein

Products: ADP; phosphate; MoO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MPLLTSADHDAIALSIRVALAATLLSIPFGFAYAYLMTFCRFRGKVLLEVLVNLPLTLPPVVMGYLLLLALGKNGWLSFL
LEPLGVRLIFTWKAAVLASAVVGFPLLVRSIRIAMEGIDSRLLQASRTLGATRLDSLFSVVLPLSKAGVVAGSSLMFARS
LGEFGATVIVAGNIPGATQTIPLAIYDYAGSPGAEGAALSLCVVAIAISVLVLLFHEALARKLAGRD

Sequences:

>Translated_227_residues
MPLLTSADHDAIALSIRVALAATLLSIPFGFAYAYLMTFCRFRGKVLLEVLVNLPLTLPPVVMGYLLLLALGKNGWLSFL
LEPLGVRLIFTWKAAVLASAVVGFPLLVRSIRIAMEGIDSRLLQASRTLGATRLDSLFSVVLPLSKAGVVAGSSLMFARS
LGEFGATVIVAGNIPGATQTIPLAIYDYAGSPGAEGAALSLCVVAIAISVLVLLFHEALARKLAGRD
>Mature_226_residues
PLLTSADHDAIALSIRVALAATLLSIPFGFAYAYLMTFCRFRGKVLLEVLVNLPLTLPPVVMGYLLLLALGKNGWLSFLL
EPLGVRLIFTWKAAVLASAVVGFPLLVRSIRIAMEGIDSRLLQASRTLGATRLDSLFSVVLPLSKAGVVAGSSLMFARSL
GEFGATVIVAGNIPGATQTIPLAIYDYAGSPGAEGAALSLCVVAIAISVLVLLFHEALARKLAGRD

Specific function: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786980, Length=228, Percent_Identity=48.2456140350877, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1788764, Length=168, Percent_Identity=36.9047619047619, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI87082099, Length=235, Percent_Identity=33.6170212765957, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787369, Length=172, Percent_Identity=28.4883720930233, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787080, Length=162, Percent_Identity=30.2469135802469, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787713, Length=237, Percent_Identity=28.2700421940928, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23878; Mature: 23747

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLTSADHDAIALSIRVALAATLLSIPFGFAYAYLMTFCRFRGKVLLEVLVNLPLTLPP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VVMGYLLLLALGKNGWLSFLLEPLGVRLIFTWKAAVLASAVVGFPLLVRSIRIAMEGIDS
HHHHHHHHHHHCCCHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLQASRTLGATRLDSLFSVVLPLSKAGVVAGSSLMFARSLGEFGATVIVAGNIPGATQT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCE
IPLAIYDYAGSPGAEGAALSLCVVAIAISVLVLLFHEALARKLAGRD
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PLLTSADHDAIALSIRVALAATLLSIPFGFAYAYLMTFCRFRGKVLLEVLVNLPLTLPP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VVMGYLLLLALGKNGWLSFLLEPLGVRLIFTWKAAVLASAVVGFPLLVRSIRIAMEGIDS
HHHHHHHHHHHCCCHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLQASRTLGATRLDSLFSVVLPLSKAGVVAGSSLMFARSLGEFGATVIVAGNIPGATQT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCE
IPLAIYDYAGSPGAEGAALSLCVVAIAISVLVLLFHEALARKLAGRD
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; MoO42- [Periplasm]; H2O [C]

Specific reaction: ATP + MoO42- [Periplasm] + H2O = ADP + phosphate + MoO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]