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The map label for this gene is coaD

Identifier: 197118274

GI number: 197118274

Start: 2191004

End: 2191489

Strand: Reverse

Name: coaD

Synonym: Gbem_1891

Alternate gene names: 197118274

Gene position: 2191489-2191004 (Counterclockwise)

Preceding gene: 197118275

Following gene: 197118273

Centisome position: 47.48

GC content: 60.7

Gene sequence:

>486_bases
GTGCCCCTGAAGCTGGCTGTATATCCAGGCTCCTTCGATCCCGTAACCTACGGGCATCTCGACATCATCGACCGCGGCCT
TAAGATCTTCGACGGCGTCATCGTGGCGGTGGCCCGCAACTCCGAGAAGAACGCGCTCTTCACCGTGCAGGAGAGAATCG
AGCTTTTGACCGAGATCCTGAAGGACCGCCCGGAGGCCAGGGTGGAGACTTTCGACGGGCTTTTGGTGGACTACGTGCGG
CGCGTCGGCGCCTCCGTCGTCATACGCGGCCTGCGCGCCGTCTCCGACTTCGAGTTCGAGTTCCAGCTGGCCCAGATGAA
CCGCAACATCACCCGCGACGTGGAAACGTTGTTCATGATGACTTCCGTCCCTTACAGCTACCTCTCCTCTTCCATAGTTA
AGGAGGTAAGCTGCCTGAACGGCCCGGTGGACAAGCTGGTCCCGCCGCTGGTGAAAAGCGCGCTGGACGCGAAATTCAGG
GGCTGA

Upstream 100 bases:

>100_bases
AAGAGATCCCCCGCAGTTTCGGCAGGCTAACGGAGATCGAGCGACGCGTCTACGGCGACACCGCCCTCTCCTTTTTAACT
ATTTCGGACAGAGGTGAAAC

Downstream 100 bases:

>100_bases
TCGGCATCGACCAGACGCTGCACCTTCTCGGAGGCCCAAGTGATCAGGAAAGAAATGACCATCAGCGAAATCCTCAGGCG
TTACCCCGAAACCCTCCCGG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MPLKLAVYPGSFDPVTYGHLDIIDRGLKIFDGVIVAVARNSEKNALFTVQERIELLTEILKDRPEARVETFDGLLVDYVR
RVGASVVIRGLRAVSDFEFEFQLAQMNRNITRDVETLFMMTSVPYSYLSSSIVKEVSCLNGPVDKLVPPLVKSALDAKFR
G

Sequences:

>Translated_161_residues
MPLKLAVYPGSFDPVTYGHLDIIDRGLKIFDGVIVAVARNSEKNALFTVQERIELLTEILKDRPEARVETFDGLLVDYVR
RVGASVVIRGLRAVSDFEFEFQLAQMNRNITRDVETLFMMTSVPYSYLSSSIVKEVSCLNGPVDKLVPPLVKSALDAKFR
G
>Mature_160_residues
PLKLAVYPGSFDPVTYGHLDIIDRGLKIFDGVIVAVARNSEKNALFTVQERIELLTEILKDRPEARVETFDGLLVDYVRR
VGASVVIRGLRAVSDFEFEFQLAQMNRNITRDVETLFMMTSVPYSYLSSSIVKEVSCLNGPVDKLVPPLVKSALDAKFRG

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=156, Percent_Identity=44.2307692307692, Blast_Score=147, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_GEOBB (B5EB44)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002138701.1
- ProteinModelPortal:   B5EB44
- SMR:   B5EB44
- GeneID:   6781881
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_1891
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18040; Mature: 17909

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKLAVYPGSFDPVTYGHLDIIDRGLKIFDGVIVAVARNSEKNALFTVQERIELLTEIL
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHH
KDRPEARVETFDGLLVDYVRRVGASVVIRGLRAVSDFEFEFQLAQMNRNITRDVETLFMM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHH
TSVPYSYLSSSIVKEVSCLNGPVDKLVPPLVKSALDAKFRG
HHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PLKLAVYPGSFDPVTYGHLDIIDRGLKIFDGVIVAVARNSEKNALFTVQERIELLTEIL
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHH
KDRPEARVETFDGLLVDYVRRVGASVVIRGLRAVSDFEFEFQLAQMNRNITRDVETLFMM
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHH
TSVPYSYLSSSIVKEVSCLNGPVDKLVPPLVKSALDAKFRG
HHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA