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The map label for this gene is mcp011 [H]

Identifier: 197118267

GI number: 197118267

Start: 2182399

End: 2184042

Strand: Reverse

Name: mcp011 [H]

Synonym: Gbem_1884

Alternate gene names: 197118267

Gene position: 2184042-2182399 (Counterclockwise)

Preceding gene: 197118270

Following gene: 197118266

Centisome position: 47.32

GC content: 62.41

Gene sequence:

>1644_bases
ATGAACTTGTGGATGAACTTGAAGGTCAAGACGAAATGCCTTTGCCTGGTAGCTATAGCGGTGGTCACTCTGACAGTATT
CGCAGCGACCAGCTTGCATAAAATGAGCGTCATGGCTGGCGACGAAAAGAACTTGAGCATAGCGGTCACCCATGTGAGCC
TCTTGAACGACATGAAGAACGATTTTCTGGCCATCAGGCTGGACCTGGTCTACATGCTGTCCCTCGAGGACACGGCAAAG
CTCAAGGAAAAGGTCGATGACCTGAACCAGCGCAAGAAGGCGATAGATGCCGGGCTGGCCAAATTCCTGAGCTATGAGTT
GGAGCCCAACGAGAAAGAGTTGATCGGGCGGTTCAAGGAGGGGTACCAGGCCTACCTGGTGCAGGGCGCGAAACTGCAGG
AACTGGCGCTGGCGGCCGTGGGTAACCCGCAGGCGCGTAGCGAGACCGTCGTATTCGCCACCGGGTCGGTGGCCCCGCTT
TACAAGAAACCTGCCGACGCCGTCACGGAACTGGTCGCCTTGAACGAAAAGGATGCCGACAAGACCTACCGGCAGGACGT
CGCCGGCTACCGTTCCGCCGTGGTGGTGATGCTGGTCCTGGCAGGTTTTGCCACCCTGTTCATGGCGCTGATAGGTCTTT
TGATCGCCAACTCCATCAGCAAGCCGCTCCAGATGGTGTTCGACACCCTGGCCGAAGTCGCCGGGGGCGACCTGACCGCG
CGTTCGGGAATCGATACCAAGGACGAAATGGGGATGCTGGCCACCGAGGTCAACGTGATGGCGGACAAGTTGAACGAGAC
CATGAACCGGGTCGCCCAGAACAGCGTGGAAGTAGCCGCTGCCGCCAGCCAGTTGCACAGCACCTCCGACCAGATAGCTA
CCGGGGCCGAGGAGGTCGCGGCCCAGACCGGCACCGTCGCAACAGCCAGCGAAGAGATGGCCGCCACCTCGTCGGAAATT
GCCCAAAGCTGCCATATGGCAGCCGAGGGGGGCAAGCAGGCGACGGACCGGGCCAAAACCGGGACCGCGGTGGTCGAGCA
GACGGTTTTGGTGATGAACCGTATCGCGCAGCAGGTGAAGTCGTCGGCTGCGACCGTAGCCGGCCTTGGCGAGCGGAGCG
ACCAGATCGGCGCCATCATCGGCACCATCGAGGACATCGCCGACCAGACGAACCTGTTGGCCTTGAACGCCGCCATCGAG
GCCGCCCGCGCCGGCGAGCAGGGGCGCGGCTTCGCGGTAGTGGCCGACGAAGTGCGGGCCCTGGCCGAGCGCACCACCCG
CGCCACCAGGGAGATCGGCGAGATGATCAAGTCGATCCAGAGCGAGACCAGGGAGGCGGTCGGCGCCATGGAGGAAGGTG
TCCGCGAGGTGGAGAACGGCACCAGGGAAGCGGCGAAGTCGGGGGATTCGCTCCAGGAAATCCTGGAGCAGATCAGCGAG
GTGACCATGCAGGTAAACCAGATCGCGACCGCAGCCGAGGAACAGACTGCCACCACCGGGGAGATCACCAACAACATCAT
GCAGATAACCGACGTGGTGCAGGATACCTCCAGGGGCGCCCACACCTGTGCCACCGCGGCGAGCCATCTTGCCGGCCTGG
CCGACGACCTGCAGCGCCTGGTCGGACAGTTCACGCTCAGGTAG

Upstream 100 bases:

>100_bases
CTAAAGTTTCACAGCGGCCATCCGATACGTCTCTCTATCAGGTCCCGAAATCCCTTCCGGGCCGGCAGCATGATGATCGA
TCTATAAAAAGGAGCCTGCG

Downstream 100 bases:

>100_bases
GAAAGTAAAACGCATCGTAAATCCGCCCCCTCCTCCCACGAACACCCGGGAGGAGGGGGTTTATTTTTCCCCAAAAAGTT
CCCCCTCCCGTCAAAGGAGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MNLWMNLKVKTKCLCLVAIAVVTLTVFAATSLHKMSVMAGDEKNLSIAVTHVSLLNDMKNDFLAIRLDLVYMLSLEDTAK
LKEKVDDLNQRKKAIDAGLAKFLSYELEPNEKELIGRFKEGYQAYLVQGAKLQELALAAVGNPQARSETVVFATGSVAPL
YKKPADAVTELVALNEKDADKTYRQDVAGYRSAVVVMLVLAGFATLFMALIGLLIANSISKPLQMVFDTLAEVAGGDLTA
RSGIDTKDEMGMLATEVNVMADKLNETMNRVAQNSVEVAAAASQLHSTSDQIATGAEEVAAQTGTVATASEEMAATSSEI
AQSCHMAAEGGKQATDRAKTGTAVVEQTVLVMNRIAQQVKSSAATVAGLGERSDQIGAIIGTIEDIADQTNLLALNAAIE
AARAGEQGRGFAVVADEVRALAERTTRATREIGEMIKSIQSETREAVGAMEEGVREVENGTREAAKSGDSLQEILEQISE
VTMQVNQIATAAEEQTATTGEITNNIMQITDVVQDTSRGAHTCATAASHLAGLADDLQRLVGQFTLR

Sequences:

>Translated_547_residues
MNLWMNLKVKTKCLCLVAIAVVTLTVFAATSLHKMSVMAGDEKNLSIAVTHVSLLNDMKNDFLAIRLDLVYMLSLEDTAK
LKEKVDDLNQRKKAIDAGLAKFLSYELEPNEKELIGRFKEGYQAYLVQGAKLQELALAAVGNPQARSETVVFATGSVAPL
YKKPADAVTELVALNEKDADKTYRQDVAGYRSAVVVMLVLAGFATLFMALIGLLIANSISKPLQMVFDTLAEVAGGDLTA
RSGIDTKDEMGMLATEVNVMADKLNETMNRVAQNSVEVAAAASQLHSTSDQIATGAEEVAAQTGTVATASEEMAATSSEI
AQSCHMAAEGGKQATDRAKTGTAVVEQTVLVMNRIAQQVKSSAATVAGLGERSDQIGAIIGTIEDIADQTNLLALNAAIE
AARAGEQGRGFAVVADEVRALAERTTRATREIGEMIKSIQSETREAVGAMEEGVREVENGTREAAKSGDSLQEILEQISE
VTMQVNQIATAAEEQTATTGEITNNIMQITDVVQDTSRGAHTCATAASHLAGLADDLQRLVGQFTLR
>Mature_547_residues
MNLWMNLKVKTKCLCLVAIAVVTLTVFAATSLHKMSVMAGDEKNLSIAVTHVSLLNDMKNDFLAIRLDLVYMLSLEDTAK
LKEKVDDLNQRKKAIDAGLAKFLSYELEPNEKELIGRFKEGYQAYLVQGAKLQELALAAVGNPQARSETVVFATGSVAPL
YKKPADAVTELVALNEKDADKTYRQDVAGYRSAVVVMLVLAGFATLFMALIGLLIANSISKPLQMVFDTLAEVAGGDLTA
RSGIDTKDEMGMLATEVNVMADKLNETMNRVAQNSVEVAAAASQLHSTSDQIATGAEEVAAQTGTVATASEEMAATSSEI
AQSCHMAAEGGKQATDRAKTGTAVVEQTVLVMNRIAQQVKSSAATVAGLGERSDQIGAIIGTIEDIADQTNLLALNAAIE
AARAGEQGRGFAVVADEVRALAERTTRATREIGEMIKSIQSETREAVGAMEEGVREVENGTREAAKSGDSLQEILEQISE
VTMQVNQIATAAEEQTATTGEITNNIMQITDVVQDTSRGAHTCATAASHLAGLADDLQRLVGQFTLR

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=324, Percent_Identity=32.4074074074074, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1787690, Length=494, Percent_Identity=26.9230769230769, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788195, Length=282, Percent_Identity=35.8156028368794, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788194, Length=357, Percent_Identity=28.8515406162465, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1789453, Length=327, Percent_Identity=26.2996941896024, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58189; Mature: 58189

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLWMNLKVKTKCLCLVAIAVVTLTVFAATSLHKMSVMAGDEKNLSIAVTHVSLLNDMKN
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
DFLAIRLDLVYMLSLEDTAKLKEKVDDLNQRKKAIDAGLAKFLSYELEPNEKELIGRFKE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GYQAYLVQGAKLQELALAAVGNPQARSETVVFATGSVAPLYKKPADAVTELVALNEKDAD
HHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHCCCCCHH
KTYRQDVAGYRSAVVVMLVLAGFATLFMALIGLLIANSISKPLQMVFDTLAEVAGGDLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RSGIDTKDEMGMLATEVNVMADKLNETMNRVAQNSVEVAAAASQLHSTSDQIATGAEEVA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHH
AQTGTVATASEEMAATSSEIAQSCHMAAEGGKQATDRAKTGTAVVEQTVLVMNRIAQQVK
HHCCCCEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSAATVAGLGERSDQIGAIIGTIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRA
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHH
LAERTTRATREIGEMIKSIQSETREAVGAMEEGVREVENGTREAAKSGDSLQEILEQISE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VTMQVNQIATAAEEQTATTGEITNNIMQITDVVQDTSRGAHTCATAASHLAGLADDLQRL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VGQFTLR
HHHHCCC
>Mature Secondary Structure
MNLWMNLKVKTKCLCLVAIAVVTLTVFAATSLHKMSVMAGDEKNLSIAVTHVSLLNDMKN
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
DFLAIRLDLVYMLSLEDTAKLKEKVDDLNQRKKAIDAGLAKFLSYELEPNEKELIGRFKE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GYQAYLVQGAKLQELALAAVGNPQARSETVVFATGSVAPLYKKPADAVTELVALNEKDAD
HHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHCCCCCHH
KTYRQDVAGYRSAVVVMLVLAGFATLFMALIGLLIANSISKPLQMVFDTLAEVAGGDLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RSGIDTKDEMGMLATEVNVMADKLNETMNRVAQNSVEVAAAASQLHSTSDQIATGAEEVA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHH
AQTGTVATASEEMAATSSEIAQSCHMAAEGGKQATDRAKTGTAVVEQTVLVMNRIAQQVK
HHCCCCEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSAATVAGLGERSDQIGAIIGTIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRA
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHH
LAERTTRATREIGEMIKSIQSETREAVGAMEEGVREVENGTREAAKSGDSLQEILEQISE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VTMQVNQIATAAEEQTATTGEITNNIMQITDVVQDTSRGAHTCATAASHLAGLADDLQRL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VGQFTLR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]