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The map label for this gene is atoS [C]

Identifier: 197118249

GI number: 197118249

Start: 2159588

End: 2161537

Strand: Reverse

Name: atoS [C]

Synonym: Gbem_1866

Alternate gene names: 197118249

Gene position: 2161537-2159588 (Counterclockwise)

Preceding gene: 197118250

Following gene: 197118248

Centisome position: 46.84

GC content: 65.28

Gene sequence:

>1950_bases
ATGCAAGCTCGCCGACCGGCCCGGCAAGTGGGAAATGAAACAGCTGACGCGTCCAGGAATGCGCCCCCCGGCGGCTCAGC
GCGCTGCCTCGCAGACCTCTGCAAACGCCTGAACGGCACGCCGGACCCGCTTGAGGCGCTGGGGGTGCTTTTGCAGGCGG
CGATGGAGGCGGTCGACGCCGCCGAGGCAAGGGGAGGGATCGTCTCCGACGACGACGTCGTGACGGAGCGCCTGTCCTGC
GGGAGCCCGGGCCAGCTGCGCCGCAGCAGTGCCGCAACCCACGCGACCTACCAGCGCCTGCTGCGGCAACCGGAGGTCTG
GATCGGCAATGACGGTGCAACCGCGGTCCCCCTGGTGGACAGCACGAAGGGCCTGGTTGCCTGGATAGAGCTGAAGCACA
CGCCCCCCCTCCCCTTCTCCGAAACGGAGGTCGAGCTGCTCGAAGCGATGGCCGCGGTGACGACACTGGCGCTGGAGACA
GCCAGGATGAGATGCGAACACCGCCATTCCAGCCGGGCCAGCGACGAGGCCAGCTCCCTGCTGTCGGCGACTATCGAGTC
CACTCTGGACGGTATCATGGCAGTCGATGCCAACGGCGACATCGTGGCGTACAACCGCCGCTTCATCCAAATGTGGGGCC
TTGAGGAAGAGGACCTGACCGGCGGGGACTGCAACCACCTGCTACTGTCGCTTCTGGGAGAGCTCAAGGACCCGGTCCTC
TTCTTCGAGAAAGTGAGCGAGCTTTACTGGCAGCCCGAATCCGAAAGCTACGACGTGGTCGAGCTGCGTAGCGGCAGGTG
CTTCGAGCGTTTCTCCCGCCCGCGCCTGACCGAGGACGGCAGGCCCGCCGGACGGGTCTGGACCTTCCACGACGTAACCG
AACTGAAGAAGCTGGAAAACCAGCTGCTGCACGCGCAGAAGATGGAGGCGATAGGAACCCTCGCCGGCGGGATCGCCCAC
GACTTCAACAACATCATGACCGCGGTGATCGGCTACACCGACCTCCTCATGCTGGAGCTCGTCCCCCCCGCGCCGTACCG
CGGCTTCCTAGAGAACATCCAGAACGCGTCGCACCGCGCCATTGCCCTGGTGAAGAACCTCCTCGCCTTCAGCAGGGAGG
AAGCGCTCCCAACCGCCAAGCTCGAGTGCAACGCCCTGCTCCAGAACGTGGCCGGGCTTATGAAAAGGTTGATCGGCCAC
GAAGTGGATTTCGTACTGAACCTGTCGAGCGCGCCGCAAGGTATCCTGGTGGACCAGGGCCAGATCGAGCAGGTGCTGGT
GAACCTCGCCACCAACGCACGGGACGCCATGCCCCACGGCGGCACCCTCACCATCGAGGTAGCCGCCATCGAACTCTCGG
CGCTGGAGCTCGCCGGACACCACACCGCGAAAGCGGGACCGTACGTGCAGATCTCCTTTTCCGACACCGGCCTCGGCATA
GACGAGAGCGTGAAAAGCAGGATCTTCGACCCCTTTTACACCACGAAGGAAGTCGGCAAAGGGTCAGGGCTCGGCCTCTC
CATTAGCTACGGCATCGTGAAGCGGCACGGCGGGTTGATCGACGTGGCGAGCGGCCAGGGTCGGGGCACCACCTTCTCCG
TGTTGCTCCCGAAGGTGGAGCTGGCCCCCGCGCTGCGCCCGCATCCCTTGGTCTCCCCGCTCAAGGAGGCGGGATCGGTC
CTGCCGGTTGACTACGATGAGCCGGTGCGCAACCCGCAAAATTCAGCCCCGTCGCCGAGCCGCCATGGTGGCCCCATGCC
CATCCCCCCGCTTGACCGTAACTCGCGGGCTGCAAGCCCCCTTTACCACCCCGTGGAGCCTTCCCATCTGCGTCCCATCT
GCGTCCCATCTGCGTCCCATCTGCGTCCCATTTGCGTCCCATCTGCGTCCCATCTCCTTCCCTCTCGATCACCGCGGCCG
GCTTTCGAGCCGCTCGCGCGCTCCTTTTAA

Upstream 100 bases:

>100_bases
GTAACACAACCACAAGAAAAGCGGTCTATGCTGACACCCACATGCAACGGCGCACGGCGCCGGCCAAGGATTCGATCCGC
GTTGACAAGGGAGAAACACG

Downstream 100 bases:

>100_bases
GAGCTACGCCGAACGTTCCGTCCGTGAAAAGGACGAATTTACGACACATTGACAGAGCTGTAACGGTTTCTAAACAAAGA
AGTTATATGAAGTATACGAG

Product: PAS domain-containing sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MQARRPARQVGNETADASRNAPPGGSARCLADLCKRLNGTPDPLEALGVLLQAAMEAVDAAEARGGIVSDDDVVTERLSC
GSPGQLRRSSAATHATYQRLLRQPEVWIGNDGATAVPLVDSTKGLVAWIELKHTPPLPFSETEVELLEAMAAVTTLALET
ARMRCEHRHSSRASDEASSLLSATIESTLDGIMAVDANGDIVAYNRRFIQMWGLEEEDLTGGDCNHLLLSLLGELKDPVL
FFEKVSELYWQPESESYDVVELRSGRCFERFSRPRLTEDGRPAGRVWTFHDVTELKKLENQLLHAQKMEAIGTLAGGIAH
DFNNIMTAVIGYTDLLMLELVPPAPYRGFLENIQNASHRAIALVKNLLAFSREEALPTAKLECNALLQNVAGLMKRLIGH
EVDFVLNLSSAPQGILVDQGQIEQVLVNLATNARDAMPHGGTLTIEVAAIELSALELAGHHTAKAGPYVQISFSDTGLGI
DESVKSRIFDPFYTTKEVGKGSGLGLSISYGIVKRHGGLIDVASGQGRGTTFSVLLPKVELAPALRPHPLVSPLKEAGSV
LPVDYDEPVRNPQNSAPSPSRHGGPMPIPPLDRNSRAASPLYHPVEPSHLRPICVPSASHLRPICVPSASHLLPSRSPRP
AFEPLARSF

Sequences:

>Translated_649_residues
MQARRPARQVGNETADASRNAPPGGSARCLADLCKRLNGTPDPLEALGVLLQAAMEAVDAAEARGGIVSDDDVVTERLSC
GSPGQLRRSSAATHATYQRLLRQPEVWIGNDGATAVPLVDSTKGLVAWIELKHTPPLPFSETEVELLEAMAAVTTLALET
ARMRCEHRHSSRASDEASSLLSATIESTLDGIMAVDANGDIVAYNRRFIQMWGLEEEDLTGGDCNHLLLSLLGELKDPVL
FFEKVSELYWQPESESYDVVELRSGRCFERFSRPRLTEDGRPAGRVWTFHDVTELKKLENQLLHAQKMEAIGTLAGGIAH
DFNNIMTAVIGYTDLLMLELVPPAPYRGFLENIQNASHRAIALVKNLLAFSREEALPTAKLECNALLQNVAGLMKRLIGH
EVDFVLNLSSAPQGILVDQGQIEQVLVNLATNARDAMPHGGTLTIEVAAIELSALELAGHHTAKAGPYVQISFSDTGLGI
DESVKSRIFDPFYTTKEVGKGSGLGLSISYGIVKRHGGLIDVASGQGRGTTFSVLLPKVELAPALRPHPLVSPLKEAGSV
LPVDYDEPVRNPQNSAPSPSRHGGPMPIPPLDRNSRAASPLYHPVEPSHLRPICVPSASHLRPICVPSASHLLPSRSPRP
AFEPLARSF
>Mature_649_residues
MQARRPARQVGNETADASRNAPPGGSARCLADLCKRLNGTPDPLEALGVLLQAAMEAVDAAEARGGIVSDDDVVTERLSC
GSPGQLRRSSAATHATYQRLLRQPEVWIGNDGATAVPLVDSTKGLVAWIELKHTPPLPFSETEVELLEAMAAVTTLALET
ARMRCEHRHSSRASDEASSLLSATIESTLDGIMAVDANGDIVAYNRRFIQMWGLEEEDLTGGDCNHLLLSLLGELKDPVL
FFEKVSELYWQPESESYDVVELRSGRCFERFSRPRLTEDGRPAGRVWTFHDVTELKKLENQLLHAQKMEAIGTLAGGIAH
DFNNIMTAVIGYTDLLMLELVPPAPYRGFLENIQNASHRAIALVKNLLAFSREEALPTAKLECNALLQNVAGLMKRLIGH
EVDFVLNLSSAPQGILVDQGQIEQVLVNLATNARDAMPHGGTLTIEVAAIELSALELAGHHTAKAGPYVQISFSDTGLGI
DESVKSRIFDPFYTTKEVGKGSGLGLSISYGIVKRHGGLIDVASGQGRGTTFSVLLPKVELAPALRPHPLVSPLKEAGSV
LPVDYDEPVRNPQNSAPSPSRHGGPMPIPPLDRNSRAASPLYHPVEPSHLRPICVPSASHLRPICVPSASHLLPSRSPRP
AFEPLARSF

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=371, Percent_Identity=28.0323450134771, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=26.1904761904762, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=27.9475982532751, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=282, Percent_Identity=23.758865248227, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790300, Length=243, Percent_Identity=28.8065843621399, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786600, Length=261, Percent_Identity=24.1379310344828, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI145693157, Length=265, Percent_Identity=24.5283018867925, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70118; Mature: 70118

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQARRPARQVGNETADASRNAPPGGSARCLADLCKRLNGTPDPLEALGVLLQAAMEAVDA
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AEARGGIVSDDDVVTERLSCGSPGQLRRSSAATHATYQRLLRQPEVWIGNDGATAVPLVD
HHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEC
STKGLVAWIELKHTPPLPFSETEVELLEAMAAVTTLALETARMRCEHRHSSRASDEASSL
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LSATIESTLDGIMAVDANGDIVAYNRRFIQMWGLEEEDLTGGDCNHLLLSLLGELKDPVL
HHHHHHHHHCCEEEECCCCCEEEECCEEEHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHH
FFEKVSELYWQPESESYDVVELRSGRCFERFSRPRLTEDGRPAGRVWTFHDVTELKKLEN
HHHHHHHHHCCCCCCCCCEEEECCCCHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
QLLHAQKMEAIGTLAGGIAHDFNNIMTAVIGYTDLLMLELVPPAPYRGFLENIQNASHRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
IALVKNLLAFSREEALPTAKLECNALLQNVAGLMKRLIGHEVDFVLNLSSAPQGILVDQG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCH
QIEQVLVNLATNARDAMPHGGTLTIEVAAIELSALELAGHHTAKAGPYVQISFSDTGLGI
HHHHHHHHHHHCHHHCCCCCCEEEEEEEEEEEHHHHHHCCCCCCCCCEEEEEECCCCCCC
DESVKSRIFDPFYTTKEVGKGSGLGLSISYGIVKRHGGLIDVASGQGRGTTFSVLLPKVE
CHHHHHHHCCCCHHHHHCCCCCCCEEEEEHHHHHHCCCEEEECCCCCCCCEEEEECCCHH
LAPALRPHPLVSPLKEAGSVLPVDYDEPVRNPQNSAPSPSRHGGPMPIPPLDRNSRAASP
HCCCCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LYHPVEPSHLRPICVPSASHLRPICVPSASHLLPSRSPRPAFEPLARSF
CCCCCCCCCCCEEECCCHHCCCEEECCCHHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MQARRPARQVGNETADASRNAPPGGSARCLADLCKRLNGTPDPLEALGVLLQAAMEAVDA
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
AEARGGIVSDDDVVTERLSCGSPGQLRRSSAATHATYQRLLRQPEVWIGNDGATAVPLVD
HHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEEC
STKGLVAWIELKHTPPLPFSETEVELLEAMAAVTTLALETARMRCEHRHSSRASDEASSL
CCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LSATIESTLDGIMAVDANGDIVAYNRRFIQMWGLEEEDLTGGDCNHLLLSLLGELKDPVL
HHHHHHHHHCCEEEECCCCCEEEECCEEEHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHH
FFEKVSELYWQPESESYDVVELRSGRCFERFSRPRLTEDGRPAGRVWTFHDVTELKKLEN
HHHHHHHHHCCCCCCCCCEEEECCCCHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
QLLHAQKMEAIGTLAGGIAHDFNNIMTAVIGYTDLLMLELVPPAPYRGFLENIQNASHRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
IALVKNLLAFSREEALPTAKLECNALLQNVAGLMKRLIGHEVDFVLNLSSAPQGILVDQG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCH
QIEQVLVNLATNARDAMPHGGTLTIEVAAIELSALELAGHHTAKAGPYVQISFSDTGLGI
HHHHHHHHHHHCHHHCCCCCCEEEEEEEEEEEHHHHHHCCCCCCCCCEEEEEECCCCCCC
DESVKSRIFDPFYTTKEVGKGSGLGLSISYGIVKRHGGLIDVASGQGRGTTFSVLLPKVE
CHHHHHHHCCCCHHHHHCCCCCCCEEEEEHHHHHHCCCEEEECCCCCCCCEEEEECCCHH
LAPALRPHPLVSPLKEAGSVLPVDYDEPVRNPQNSAPSPSRHGGPMPIPPLDRNSRAASP
HCCCCCCCCHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LYHPVEPSHLRPICVPSASHLRPICVPSASHLLPSRSPRPAFEPLARSF
CCCCCCCCCCCEEECCCHHCCCEEECCCHHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA