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The map label for this gene is aroB-2 [H]

Identifier: 197118201

GI number: 197118201

Start: 2100891

End: 2102099

Strand: Direct

Name: aroB-2 [H]

Synonym: Gbem_1816

Alternate gene names: 197118201

Gene position: 2100891-2102099 (Clockwise)

Preceding gene: 197118200

Following gene: 197118202

Centisome position: 45.52

GC content: 64.35

Gene sequence:

>1209_bases
ATGAAGACCATCCAGCAGCATTTCACCGTCGCCTATTCCTTTCCGGTGATCTTCACCAGCGACGCCTTCGGAGCCGGCAG
CGCCGCGCTTTTGCGGGTCCTGGCAGGCGAAGGGGAAAGACCCCGGGTGCTGACCGTGATCGACTCGAAGGTGCTCCGGA
TCAACCCGGATCTGCTGGAGAAGCTGAACCGTTTTGCGGCGGACCACTCCGCCGAAGTGGAAATCCTCGTTCCCCCGCTG
GTTATGCGGGGAGGCGAGGCGTGCAAGAACGAGCCTGGGGAGGTGGAGAAGATCCACGCCCTGGTGGAGCGCCACGGCCT
TTGCCGGCACTCCTTCATCCTTGCCATCGGCGGCGGCGCCGTCTTGGACGCGGCCGGGTTCGCCGCCGCCACCGCGCACC
GCGGCGTCCGCCTGGTGCGGATGCCCACCACCACCCTTTCCATGAACGACGCCGGGGTGGGGGTGAAAAACGGCGTCAAC
GCCTTCGGGCGCAAGAACTTCACCGGCTGCTTCGCCCCCCCATTCGCCGTCGTGAACGACTTCGACTTTCTCAGGCTCCT
GCCGGCCAGGGAGCTTCGGGCGGGCATCGCCGAGGCGGTGAAGGTGGCTCTCATCAGGGACCGCGCCTTTTTCGATTTCC
TCTACGCCTCGCGCGCACTGCTCGCCGCCTTCGAGTCCGAGGTCATGCAGCGCATGATCGTCCGTTGCGCCGAACTGCAC
CTGGAGCACATCGCCACTAGCGGCGACCCCTTCGAGTTCGGCTCGTCGCGCCCTTTGGACTTCGGGCACTGGTCCGCGCA
CAAACTGGAGGAGCTGACCCAGGGCGAGATCAGGCACGGCGAGGCGGTCGCCATCGGCATCGCGCTCGATTCCCTCTACT
CCTTCGAGCTCGGTATGATAGGGGAGCTCGACCTGCGCCGCATCCTCGCCACCCTGGAAGGGATCGGCTTCCAGCTTTAC
CACCTTGCCCTGGAATGGGTCGACGTGGAAAAGTCGCTGCGGCAGTTCCAGGAGCACCTGGGAGGGGAGCTTTCCATCCC
GCTTCTGGACGGCATCGGCGCCAGATCGGACCGGCACGACATAGATGCGGCTCTCTACCGCAAATGCATCAAGACACTCG
CCTCGCGCAGGAATCAGACGGAGAAAAGCGATGACCGGAAAAAGCTGCAGCCTGACCTCCCAGGAGATCCTGGACACCTA
CTTCCTTGA

Upstream 100 bases:

>100_bases
CCACCGGCCGCTGGTGGGAGAGGGATCCGGTCCTGGTCACCTCCTATTCCGTGCTCACCCTGGAGATCCTGTACCGGGGA
CTGTGATTGAGGGAGGGGGC

Downstream 100 bases:

>100_bases
AAACCGGGCCCGCCTGCTGGAGATAGCGTCGTTTCTGGACCGCCTGGACCGCGCCGCCGATGCCGGAGAGGCGAGGGGGG
AGTATCGCCGGCGCGCCTTC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MKTIQQHFTVAYSFPVIFTSDAFGAGSAALLRVLAGEGERPRVLTVIDSKVLRINPDLLEKLNRFAADHSAEVEILVPPL
VMRGGEACKNEPGEVEKIHALVERHGLCRHSFILAIGGGAVLDAAGFAAATAHRGVRLVRMPTTTLSMNDAGVGVKNGVN
AFGRKNFTGCFAPPFAVVNDFDFLRLLPARELRAGIAEAVKVALIRDRAFFDFLYASRALLAAFESEVMQRMIVRCAELH
LEHIATSGDPFEFGSSRPLDFGHWSAHKLEELTQGEIRHGEAVAIGIALDSLYSFELGMIGELDLRRILATLEGIGFQLY
HLALEWVDVEKSLRQFQEHLGGELSIPLLDGIGARSDRHDIDAALYRKCIKTLASRRNQTEKSDDRKKLQPDLPGDPGHL
LP

Sequences:

>Translated_402_residues
MKTIQQHFTVAYSFPVIFTSDAFGAGSAALLRVLAGEGERPRVLTVIDSKVLRINPDLLEKLNRFAADHSAEVEILVPPL
VMRGGEACKNEPGEVEKIHALVERHGLCRHSFILAIGGGAVLDAAGFAAATAHRGVRLVRMPTTTLSMNDAGVGVKNGVN
AFGRKNFTGCFAPPFAVVNDFDFLRLLPARELRAGIAEAVKVALIRDRAFFDFLYASRALLAAFESEVMQRMIVRCAELH
LEHIATSGDPFEFGSSRPLDFGHWSAHKLEELTQGEIRHGEAVAIGIALDSLYSFELGMIGELDLRRILATLEGIGFQLY
HLALEWVDVEKSLRQFQEHLGGELSIPLLDGIGARSDRHDIDAALYRKCIKTLASRRNQTEKSDDRKKLQPDLPGDPGHL
LP
>Mature_402_residues
MKTIQQHFTVAYSFPVIFTSDAFGAGSAALLRVLAGEGERPRVLTVIDSKVLRINPDLLEKLNRFAADHSAEVEILVPPL
VMRGGEACKNEPGEVEKIHALVERHGLCRHSFILAIGGGAVLDAAGFAAATAHRGVRLVRMPTTTLSMNDAGVGVKNGVN
AFGRKNFTGCFAPPFAVVNDFDFLRLLPARELRAGIAEAVKVALIRDRAFFDFLYASRALLAAFESEVMQRMIVRCAELH
LEHIATSGDPFEFGSSRPLDFGHWSAHKLEELTQGEIRHGEAVAIGIALDSLYSFELGMIGELDLRRILATLEGIGFQLY
HLALEWVDVEKSLRQFQEHLGGELSIPLLDGIGARSDRHDIDAALYRKCIKTLASRRNQTEKSDDRKKLQPDLPGDPGHL
LP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=307, Percent_Identity=34.8534201954397, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320332, Length=263, Percent_Identity=29.6577946768061, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 44147; Mature: 44147

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIQQHFTVAYSFPVIFTSDAFGAGSAALLRVLAGEGERPRVLTVIDSKVLRINPDLLE
CCCHHHHEEEEEECCEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCEEEECHHHHH
KLNRFAADHSAEVEILVPPLVMRGGEACKNEPGEVEKIHALVERHGLCRHSFILAIGGGA
HHHHHHCCCCCCEEEEECCHHHCCCHHHCCCCCHHHHHHHHHHHCCCHHHEEEEEECCCH
VLDAAGFAAATAHRGVRLVRMPTTTLSMNDAGVGVKNGVNAFGRKNFTGCFAPPFAVVND
HHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCHHCCCCHHCCCCCCCCCCCCHHHHCC
FDFLRLLPARELRAGIAEAVKVALIRDRAFFDFLYASRALLAAFESEVMQRMIVRCAELH
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHIATSGDPFEFGSSRPLDFGHWSAHKLEELTQGEIRHGEAVAIGIALDSLYSFELGMI
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHCCCCC
GELDLRRILATLEGIGFQLYHLALEWVDVEKSLRQFQEHLGGELSIPLLDGIGARSDRHD
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHCCCCCCCCCCHH
IDAALYRKCIKTLASRRNQTEKSDDRKKLQPDLPGDPGHLLP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKTIQQHFTVAYSFPVIFTSDAFGAGSAALLRVLAGEGERPRVLTVIDSKVLRINPDLLE
CCCHHHHEEEEEECCEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCEEEECHHHHH
KLNRFAADHSAEVEILVPPLVMRGGEACKNEPGEVEKIHALVERHGLCRHSFILAIGGGA
HHHHHHCCCCCCEEEEECCHHHCCCHHHCCCCCHHHHHHHHHHHCCCHHHEEEEEECCCH
VLDAAGFAAATAHRGVRLVRMPTTTLSMNDAGVGVKNGVNAFGRKNFTGCFAPPFAVVND
HHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCHHCCCCHHCCCCCCCCCCCCHHHHCC
FDFLRLLPARELRAGIAEAVKVALIRDRAFFDFLYASRALLAAFESEVMQRMIVRCAELH
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHIATSGDPFEFGSSRPLDFGHWSAHKLEELTQGEIRHGEAVAIGIALDSLYSFELGMI
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHCCCCC
GELDLRRILATLEGIGFQLYHLALEWVDVEKSLRQFQEHLGGELSIPLLDGIGARSDRHD
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHCCCCCCCCCCHH
IDAALYRKCIKTLASRRNQTEKSDDRKKLQPDLPGDPGHLLP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA