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The map label for this gene is dinB [H]

Identifier: 197118141

GI number: 197118141

Start: 2024621

End: 2025850

Strand: Reverse

Name: dinB [H]

Synonym: Gbem_1756

Alternate gene names: 197118141

Gene position: 2025850-2024621 (Counterclockwise)

Preceding gene: 197118142

Following gene: 197118138

Centisome position: 43.9

GC content: 56.42

Gene sequence:

>1230_bases
TTGGAAGCCAATCGCATCATCCTTCACATCGACATGAACGCCTTCTTCGCCTCGGTGGAACAGCAGTCGAACCCAGCGCT
GGCCGGCAAGCCCGTTGCCGTCATCGGTGCGGCCAAGCGAACCATCATCACCACCTGTTCCTACGAAGCACGCGCTTTCG
GAGTCAAGACCGGAATGAACAGCTGGGAGGCCCGCCAGAAATGCCCCCAGCTTATTTTCGTTGTCGGCAACAACCGCAAA
TACAGCTACACCTCAAAACAGATCATCGCCATCATGCGTGAGTACACCCCGCAGGTAGAGGTTTTCTCCATCGACGAAGC
CTTCCTCGACGTCACCGGGAGTCTATCGCTCTTCGGCTCGGCCAAAAAGATCGCCTATCTCATCAAGCAGCAGATCAGGG
AACGGTTCGGCCTTACCTGCTCGGTCGGGATAGCTCCCAACAAACTCTTAGCCAAACTTGCCTCCGACATGCAAAAGCCT
GACGGACTGACCGTCGTCGATCCGGAAAAAGTGGCCCAGGTAATGGAACGGCTACCGATCCAGGCGTTGTGCGGCATAGG
GGCCAAGATGCAGCAACACTTGGCGAAATTCGGCATCAAAACCTGCGGCGAACTCGGGAGATTTCCGGTTGAGACGCTGA
AGAAGCATTTTGGCATAACCGGGGAAAAACTGCATTTCATGGGACTCGGGGTGGACGACTCGCCGGTGGTCCCTGAAGAC
GAGGCCGAGGAGGTGAAAAGCGTCGGCCACAGCACCACCTTGGACCGTGACATCACGGGGCGAAGCGAGATTCTGCTCCA
CCTGCTTCAGCTTTCGGAGATGGTGGGAAGGCGCGCCAGGAAATACCAGGTAACCGGCCGGACCGTCACCCTCACCGTCC
GCTATGCCGATTTCACCACCTTCTCCAAACAGCAAAGCCGCGGAGACTACACCAACAACAGCGAGGAAATATATCAAACG
GCGGTAAAGATCCTGGATAACTTGGACCTGACGCAACCGGTCCGGCTCCTGGGGATAAAAATCGCCAACCTCAGACACCA
TACCGAACAGTTGCCGCTTTTTGCCGAGGAACGAAAAAAGGCGCTCGTCGCGAGCGCCATGGATAATGTGAACAACAAGT
TCGGTGATTTCGCCGTCACCTTTGGGAGTTTACTCGGTAAAGAAAAGGGGGCGAAGGTGATCTCGCCCGCGTGGAGGCCG
GAGGGGGTCAGGAACGTCGATGCCGATTGA

Upstream 100 bases:

>100_bases
CGCGGTAAGCGATGGCAGCAATCTCTTTGAGCTCATGTTCGACACCTCCGATCAGAGTTGGACCCTGATATCAGTCTAGG
AGCAGTAGCCGGGACGAGAA

Downstream 100 bases:

>100_bases
CGCCCTCTAAAACCCCGGCACCCCGGTAGGCACCTGGTCCCAGTAGGTGACCATGCCGTTATGCCACTTCACTATCTGTA
CGCTCTCATCCTGCGAGATG

Product: DNA polymerase IV kappa

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MEANRIILHIDMNAFFASVEQQSNPALAGKPVAVIGAAKRTIITTCSYEARAFGVKTGMNSWEARQKCPQLIFVVGNNRK
YSYTSKQIIAIMREYTPQVEVFSIDEAFLDVTGSLSLFGSAKKIAYLIKQQIRERFGLTCSVGIAPNKLLAKLASDMQKP
DGLTVVDPEKVAQVMERLPIQALCGIGAKMQQHLAKFGIKTCGELGRFPVETLKKHFGITGEKLHFMGLGVDDSPVVPED
EAEEVKSVGHSTTLDRDITGRSEILLHLLQLSEMVGRRARKYQVTGRTVTLTVRYADFTTFSKQQSRGDYTNNSEEIYQT
AVKILDNLDLTQPVRLLGIKIANLRHHTEQLPLFAEERKKALVASAMDNVNNKFGDFAVTFGSLLGKEKGAKVISPAWRP
EGVRNVDAD

Sequences:

>Translated_409_residues
MEANRIILHIDMNAFFASVEQQSNPALAGKPVAVIGAAKRTIITTCSYEARAFGVKTGMNSWEARQKCPQLIFVVGNNRK
YSYTSKQIIAIMREYTPQVEVFSIDEAFLDVTGSLSLFGSAKKIAYLIKQQIRERFGLTCSVGIAPNKLLAKLASDMQKP
DGLTVVDPEKVAQVMERLPIQALCGIGAKMQQHLAKFGIKTCGELGRFPVETLKKHFGITGEKLHFMGLGVDDSPVVPED
EAEEVKSVGHSTTLDRDITGRSEILLHLLQLSEMVGRRARKYQVTGRTVTLTVRYADFTTFSKQQSRGDYTNNSEEIYQT
AVKILDNLDLTQPVRLLGIKIANLRHHTEQLPLFAEERKKALVASAMDNVNNKFGDFAVTFGSLLGKEKGAKVISPAWRP
EGVRNVDAD
>Mature_409_residues
MEANRIILHIDMNAFFASVEQQSNPALAGKPVAVIGAAKRTIITTCSYEARAFGVKTGMNSWEARQKCPQLIFVVGNNRK
YSYTSKQIIAIMREYTPQVEVFSIDEAFLDVTGSLSLFGSAKKIAYLIKQQIRERFGLTCSVGIAPNKLLAKLASDMQKP
DGLTVVDPEKVAQVMERLPIQALCGIGAKMQQHLAKFGIKTCGELGRFPVETLKKHFGITGEKLHFMGLGVDDSPVVPED
EAEEVKSVGHSTTLDRDITGRSEILLHLLQLSEMVGRRARKYQVTGRTVTLTVRYADFTTFSKQQSRGDYTNNSEEIYQT
AVKILDNLDLTQPVRLLGIKIANLRHHTEQLPLFAEERKKALVASAMDNVNNKFGDFAVTFGSLLGKEKGAKVISPAWRP
EGVRNVDAD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=283, Percent_Identity=31.8021201413428, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI84043967, Length=256, Percent_Identity=34.765625, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI7706681, Length=256, Percent_Identity=34.765625, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI7705344, Length=109, Percent_Identity=43.1192660550459, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI5729982, Length=121, Percent_Identity=37.1900826446281, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786425, Length=354, Percent_Identity=35.3107344632768, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1787432, Length=228, Percent_Identity=33.7719298245614, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193205700, Length=423, Percent_Identity=28.3687943262411, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17537959, Length=209, Percent_Identity=33.9712918660287, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI115534089, Length=148, Percent_Identity=39.1891891891892, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193205702, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21355641, Length=305, Percent_Identity=31.4754098360656, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24644984, Length=305, Percent_Identity=31.4754098360656, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI19923006, Length=341, Percent_Identity=26.099706744868, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24668444, Length=122, Percent_Identity=31.9672131147541, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45278; Mature: 45278

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50173 UMUC ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEANRIILHIDMNAFFASVEQQSNPALAGKPVAVIGAAKRTIITTCSYEARAFGVKTGMN
CCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCHHHEEHHCCCC
SWEARQKCPQLIFVVGNNRKYSYTSKQIIAIMREYTPQVEVFSIDEAFLDVTGSLSLFGS
CHHHHHCCCEEEEEEECCEEECCHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCHHHHCC
AKKIAYLIKQQIRERFGLTCSVGIAPNKLLAKLASDMQKPDGLTVVDPEKVAQVMERLPI
HHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCH
QALCGIGAKMQQHLAKFGIKTCGELGRFPVETLKKHFGITGEKLHFMGLGVDDSPVVPED
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
EAEEVKSVGHSTTLDRDITGRSEILLHLLQLSEMVGRRARKYQVTGRTVTLTVRYADFTT
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEECCHH
FSKQQSRGDYTNNSEEIYQTAVKILDNLDLTQPVRLLGIKIANLRHHTEQLPLFAEERKK
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
ALVASAMDNVNNKFGDFAVTFGSLLGKEKGAKVISPAWRPEGVRNVDAD
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEANRIILHIDMNAFFASVEQQSNPALAGKPVAVIGAAKRTIITTCSYEARAFGVKTGMN
CCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCHHHEEHHCCCC
SWEARQKCPQLIFVVGNNRKYSYTSKQIIAIMREYTPQVEVFSIDEAFLDVTGSLSLFGS
CHHHHHCCCEEEEEEECCEEECCHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCHHHHCC
AKKIAYLIKQQIRERFGLTCSVGIAPNKLLAKLASDMQKPDGLTVVDPEKVAQVMERLPI
HHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHCCH
QALCGIGAKMQQHLAKFGIKTCGELGRFPVETLKKHFGITGEKLHFMGLGVDDSPVVPED
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
EAEEVKSVGHSTTLDRDITGRSEILLHLLQLSEMVGRRARKYQVTGRTVTLTVRYADFTT
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEECCHH
FSKQQSRGDYTNNSEEIYQTAVKILDNLDLTQPVRLLGIKIANLRHHTEQLPLFAEERKK
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
ALVASAMDNVNNKFGDFAVTFGSLLGKEKGAKVISPAWRPEGVRNVDAD
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA