Click here to switch to the map view.

The map label for this gene is cheA-1 [H]

Identifier: 197117981

GI number: 197117981

Start: 1847318

End: 1849408

Strand: Direct

Name: cheA-1 [H]

Synonym: Gbem_1594

Alternate gene names: 197117981

Gene position: 1847318-1849408 (Clockwise)

Preceding gene: 197117980

Following gene: 308535251

Centisome position: 40.03

GC content: 63.94

Gene sequence:

>2091_bases
ATGATAGACCAGCACCGGCAGGCATTCAAGGAAGAGGCGTACGAGCTCCTGGCTGAACTGGAGACCTCGCTTTTGGAGCT
TGAGGAGCAGCCGGACGATGTCGACGTCATCGGCAGGGTTTTCCGCGCCATGCACACCATCAAGGGCTCGGGATCGATGT
TCGGCTTTGACGACATCGCCGCTTTCACCCATGAGGTGGAGACCATCTTCGACATGGTCCGCAACGGCAAGCTGAAGGTG
ACCGGCCGCCTGGTCAACCTGACGCTCGCGGCGCGGGACCAGATCCGCGCCATGCTGGACGGGGCCGACGACGGGGGGGG
AGGGGTGGACCTCAAGGCCAGCGGGGAAATCATCATGGGACTGCGCGAGCTGGCCGGCTTCCAGCCGGCCGCAGCAGAGC
CCCCCGAGGCTGCCGCGGCCGCCCAAAAGCCGGTCAATCTGGCCACCTATCGGATCCGCTTCGCACCGTCCCGGGACATC
TTCATCACCGGGACCAATCCGCTTACGCTGCTGCAGGAGCTAAAGGAGCTGGGGACCTGCTCGGTGGTGGCGCAGACCGG
CGATTTCCCCTGCCTCGAGGAGATCGACCCCGAGGCCTGCTACGTTTATTGGGACCTGATACTGACCACCGACCAGGGCG
ACAACGCGATCAGGGACGTCTTCATCTTCGTCGAGGACGACTGCGAGTTGAGGATAGAGCAGGTGGCGGAGCATACCCAG
TTCGACGAGCCGCAGGACTACAAGAAGCTCGGGATGATCCTCTTGGAGCGTGGGGACATCACTACCGAAGAGATGGAGGA
GATACTCGCCCAGCAGCATAAGTTCGGCGAACTGGCCGTGTCGAACGGTATCCTGGACCAGGGTAAGGTGCAGTCCGCCC
TCGTGGAGCAGCGGCACGTCAAGGAGGTGCGCCAGGAGAAGCAGGCGACCGAAGCCGCCTCCAGCATCCGGGTCCCCGCC
GAGCGCCTCGACCTTTTGGTAAACCTGGTCGGGGAGATGGTCACCGTGCAGGCGCGCCTCTCCCAGACGGCGGCGCAGCG
GGAGGACGCGGAGCTTGTGGCCATTGCCGAGGAGGTGGAGCGCCTCACCGCGGAACTCAGGGACAGCGCGCTCAACATCC
GGATGCTTCCCATCGGCAGTACCTTCAGCAAGTTCAAGCGCCTGGTGCGCGATCTCTCGGTCGAACTCGGCAAGCAGATC
GAGATTACCACCGAGGGGGCCGAGACCGAGCTGGACAAGACGGTGATCGAGAAGCTGAACGACCCGCTGGTGCACCTGAT
CCGCAACAGCATCGACCACGGCATCGAACTCCCCGAGGCCCGGGTGGAGGCAGGCAAGCCCGCCCACGGCACCGTGCACC
TTGCCGCGGTTCATTCCGGCGACAGCGTCGTCATCACCATAGACGACGACGGCGCCGGGCTCGACAAGGAGGCCATCAGG
GCCAAGGCGATCGAGAAGGGGATCATCGCCGCCACGGCGGAGTTGAGCGACAAGGAACTCTTCTCGCTCATCTTCGCGCC
TGGCTTCTCCACGGCGAAAAAGATCTCCTCCGTCTCCGGGCGCGGGGTGGGGATGGACGTGGTGAAGCGGGCCATTGAGC
TCTTACGGGGGAGCATCGACATCTCCAGCGTGCAAGGAAAGGGGACCCGCATCGCGGTGAAGATCCCTCTTACCCTGGCC
ATCATCGAGAGCCTCAGGGTGCAGATCGGGGAGGACTCCTTCATGCTGCCGCTTTCCCTGGTGGACGAGTGCGTGGAACT
GACCCGCGAGGACGTGGAGCGTTCCCACGGCCGCAACCTGGCCCACGTGAGGGCGCAGTTGATTCCGTACATCCCGCTCA
GGGAACACTTCCGGATCCAGGGAACCCCTCCGGAGATCCAGCAGATCGTCATCACCCAGATGAACGGCAGCCGGGTCGGC
TTCGTGGTGGATCAGGTGATCGGGGAGCACCAGACGGTGATCAAGTCGCTGGGGCGCGCCTACAGGGATGTGGACGGCAT
TTCCGGCGCCACCATCCTAGGCGACGGATCCGTAGCGCTGATCCTGGACGTGCCGCAACTATTGCAGGCGGTGGAAGCCG
GGCAGGCTTAA

Upstream 100 bases:

>100_bases
ACTCCAAGAAGCAGGAAGGAAAGGCGGCCGGCGCCACGGGATGGATCGTGAAACCCTTTAAGCCGGAACAGTTGATGGCG
GTGGTGAAGAAGGTGCTCGG

Downstream 100 bases:

>100_bases
CTGCGGTTCTACTTCTAACTGCAGAACGTAGAACAGACTTTGACTTTCACGTAGAACATAGAACGTTGGACGTTGAACAG
CCTTTGAGGGAGTGATGAAT

Product: chemotaxis sensor histidine kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MIDQHRQAFKEEAYELLAELETSLLELEEQPDDVDVIGRVFRAMHTIKGSGSMFGFDDIAAFTHEVETIFDMVRNGKLKV
TGRLVNLTLAARDQIRAMLDGADDGGGGVDLKASGEIIMGLRELAGFQPAAAEPPEAAAAAQKPVNLATYRIRFAPSRDI
FITGTNPLTLLQELKELGTCSVVAQTGDFPCLEEIDPEACYVYWDLILTTDQGDNAIRDVFIFVEDDCELRIEQVAEHTQ
FDEPQDYKKLGMILLERGDITTEEMEEILAQQHKFGELAVSNGILDQGKVQSALVEQRHVKEVRQEKQATEAASSIRVPA
ERLDLLVNLVGEMVTVQARLSQTAAQREDAELVAIAEEVERLTAELRDSALNIRMLPIGSTFSKFKRLVRDLSVELGKQI
EITTEGAETELDKTVIEKLNDPLVHLIRNSIDHGIELPEARVEAGKPAHGTVHLAAVHSGDSVVITIDDDGAGLDKEAIR
AKAIEKGIIAATAELSDKELFSLIFAPGFSTAKKISSVSGRGVGMDVVKRAIELLRGSIDISSVQGKGTRIAVKIPLTLA
IIESLRVQIGEDSFMLPLSLVDECVELTREDVERSHGRNLAHVRAQLIPYIPLREHFRIQGTPPEIQQIVITQMNGSRVG
FVVDQVIGEHQTVIKSLGRAYRDVDGISGATILGDGSVALILDVPQLLQAVEAGQA

Sequences:

>Translated_696_residues
MIDQHRQAFKEEAYELLAELETSLLELEEQPDDVDVIGRVFRAMHTIKGSGSMFGFDDIAAFTHEVETIFDMVRNGKLKV
TGRLVNLTLAARDQIRAMLDGADDGGGGVDLKASGEIIMGLRELAGFQPAAAEPPEAAAAAQKPVNLATYRIRFAPSRDI
FITGTNPLTLLQELKELGTCSVVAQTGDFPCLEEIDPEACYVYWDLILTTDQGDNAIRDVFIFVEDDCELRIEQVAEHTQ
FDEPQDYKKLGMILLERGDITTEEMEEILAQQHKFGELAVSNGILDQGKVQSALVEQRHVKEVRQEKQATEAASSIRVPA
ERLDLLVNLVGEMVTVQARLSQTAAQREDAELVAIAEEVERLTAELRDSALNIRMLPIGSTFSKFKRLVRDLSVELGKQI
EITTEGAETELDKTVIEKLNDPLVHLIRNSIDHGIELPEARVEAGKPAHGTVHLAAVHSGDSVVITIDDDGAGLDKEAIR
AKAIEKGIIAATAELSDKELFSLIFAPGFSTAKKISSVSGRGVGMDVVKRAIELLRGSIDISSVQGKGTRIAVKIPLTLA
IIESLRVQIGEDSFMLPLSLVDECVELTREDVERSHGRNLAHVRAQLIPYIPLREHFRIQGTPPEIQQIVITQMNGSRVG
FVVDQVIGEHQTVIKSLGRAYRDVDGISGATILGDGSVALILDVPQLLQAVEAGQA
>Mature_696_residues
MIDQHRQAFKEEAYELLAELETSLLELEEQPDDVDVIGRVFRAMHTIKGSGSMFGFDDIAAFTHEVETIFDMVRNGKLKV
TGRLVNLTLAARDQIRAMLDGADDGGGGVDLKASGEIIMGLRELAGFQPAAAEPPEAAAAAQKPVNLATYRIRFAPSRDI
FITGTNPLTLLQELKELGTCSVVAQTGDFPCLEEIDPEACYVYWDLILTTDQGDNAIRDVFIFVEDDCELRIEQVAEHTQ
FDEPQDYKKLGMILLERGDITTEEMEEILAQQHKFGELAVSNGILDQGKVQSALVEQRHVKEVRQEKQATEAASSIRVPA
ERLDLLVNLVGEMVTVQARLSQTAAQREDAELVAIAEEVERLTAELRDSALNIRMLPIGSTFSKFKRLVRDLSVELGKQI
EITTEGAETELDKTVIEKLNDPLVHLIRNSIDHGIELPEARVEAGKPAHGTVHLAAVHSGDSVVITIDDDGAGLDKEAIR
AKAIEKGIIAATAELSDKELFSLIFAPGFSTAKKISSVSGRGVGMDVVKRAIELLRGSIDISSVQGKGTRIAVKIPLTLA
IIESLRVQIGEDSFMLPLSLVDECVELTREDVERSHGRNLAHVRAQLIPYIPLREHFRIQGTPPEIQQIVITQMNGSRVG
FVVDQVIGEHQTVIKSLGRAYRDVDGISGATILGDGSVALILDVPQLLQAVEAGQA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=713, Percent_Identity=36.0448807854137, Blast_Score=388, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76097; Mature: 76097

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDQHRQAFKEEAYELLAELETSLLELEEQPDDVDVIGRVFRAMHTIKGSGSMFGFDDIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
AFTHEVETIFDMVRNGKLKVTGRLVNLTLAARDQIRAMLDGADDGGGGVDLKASGEIIMG
HHHHHHHHHHHHHHCCCEEEEEEEEEEEEHHHHHHHHHHCCCCCCCCCEEEEECCHHHHH
LRELAGFQPAAAEPPEAAAAAQKPVNLATYRIRFAPSRDIFITGTNPLTLLQELKELGTC
HHHHCCCCCCCCCCCHHHHHHCCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHHHCCCE
SVVAQTGDFPCLEEIDPEACYVYWDLILTTDQGDNAIRDVFIFVEDDCELRIEQVAEHTQ
EEEEECCCCCCHHHCCCCEEEEEEEEEEEECCCCCCEEEEEEEEECCCHHHHHHHHHHCC
FDEPQDYKKLGMILLERGDITTEEMEEILAQQHKFGELAVSNGILDQGKVQSALVEQRHV
CCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHH
KEVRQEKQATEAASSIRVPAERLDLLVNLVGEMVTVQARLSQTAAQREDAELVAIAEEVE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RLTAELRDSALNIRMLPIGSTFSKFKRLVRDLSVELGKQIEITTEGAETELDKTVIEKLN
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCC
DPLVHLIRNSIDHGIELPEARVEAGKPAHGTVHLAAVHSGDSVVITIDDDGAGLDKEAIR
CHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHH
AKAIEKGIIAATAELSDKELFSLIFAPGFSTAKKISSVSGRGVGMDVVKRAIELLRGSID
HHHHHCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
ISSVQGKGTRIAVKIPLTLAIIESLRVQIGEDSFMLPLSLVDECVELTREDVERSHGRNL
EEECCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCH
AHVRAQLIPYIPLREHFRIQGTPPEIQQIVITQMNGSRVGFVVDQVIGEHQTVIKSLGRA
HHHHHHHCCCCCCCCCEEECCCCHHHHEEEEEECCCCEEHHHHHHHHCCHHHHHHHHHHH
YRDVDGISGATILGDGSVALILDVPQLLQAVEAGQA
HHHCCCCCCCEEECCCCEEEEECHHHHHHHHHCCCC
>Mature Secondary Structure
MIDQHRQAFKEEAYELLAELETSLLELEEQPDDVDVIGRVFRAMHTIKGSGSMFGFDDIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
AFTHEVETIFDMVRNGKLKVTGRLVNLTLAARDQIRAMLDGADDGGGGVDLKASGEIIMG
HHHHHHHHHHHHHHCCCEEEEEEEEEEEEHHHHHHHHHHCCCCCCCCCEEEEECCHHHHH
LRELAGFQPAAAEPPEAAAAAQKPVNLATYRIRFAPSRDIFITGTNPLTLLQELKELGTC
HHHHCCCCCCCCCCCHHHHHHCCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHHHCCCE
SVVAQTGDFPCLEEIDPEACYVYWDLILTTDQGDNAIRDVFIFVEDDCELRIEQVAEHTQ
EEEEECCCCCCHHHCCCCEEEEEEEEEEEECCCCCCEEEEEEEEECCCHHHHHHHHHHCC
FDEPQDYKKLGMILLERGDITTEEMEEILAQQHKFGELAVSNGILDQGKVQSALVEQRHV
CCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHH
KEVRQEKQATEAASSIRVPAERLDLLVNLVGEMVTVQARLSQTAAQREDAELVAIAEEVE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RLTAELRDSALNIRMLPIGSTFSKFKRLVRDLSVELGKQIEITTEGAETELDKTVIEKLN
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCC
DPLVHLIRNSIDHGIELPEARVEAGKPAHGTVHLAAVHSGDSVVITIDDDGAGLDKEAIR
CHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHH
AKAIEKGIIAATAELSDKELFSLIFAPGFSTAKKISSVSGRGVGMDVVKRAIELLRGSID
HHHHHCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
ISSVQGKGTRIAVKIPLTLAIIESLRVQIGEDSFMLPLSLVDECVELTREDVERSHGRNL
EEECCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCH
AHVRAQLIPYIPLREHFRIQGTPPEIQQIVITQMNGSRVGFVVDQVIGEHQTVIKSLGRA
HHHHHHHCCCCCCCCCEEECCCCHHHHEEEEEECCCCEEHHHHHHHHCCHHHHHHHHHHH
YRDVDGISGATILGDGSVALILDVPQLLQAVEAGQA
HHHCCCCCCCEEECCCCEEEEECHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]