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The map label for this gene is celB [H]

Identifier: 197117954

GI number: 197117954

Start: 1814665

End: 1816089

Strand: Direct

Name: celB [H]

Synonym: Gbem_1567

Alternate gene names: 197117954

Gene position: 1814665-1816089 (Clockwise)

Preceding gene: 197117951

Following gene: 308535249

Centisome position: 39.32

GC content: 62.46

Gene sequence:

>1425_bases
ATGCAGCGTATCACTTTCGGCACCTCTGGCTGGCGCGGCATCATGTGTGAAGATTTCATCTTTGAGAATGTGAAGGTAGT
CACTCAGGCCATTGCGGACAACGTCAAGGCCTCCGGCGAGGCGCGCAAGGGAATCATCGTAGGGTACGACTCCCGTTTCA
TGGGCGAATCCTTCGCCCGTGAGGCCGCCCGCGTGCTGACTGGAGCCGGCATCACCACCTATCTTTGCATCCGCGACACC
CCCACCCCTGTAATCGCTTTCGAGATCCTCAGGCGCGGCACGGCAGGCGCCATCAACTTCACCGCCAGCCACAATCCCCC
CGAATATAACGGCATCAAGTTTTCCCCCTCCTGGGGGGGACCTGCCCTGCCGCAGACCACCACCGACATCGAAAACCGCG
CCAACGAGATGGCGGGAGAGATCTGCTACACGGAGTGCTCCATCGACGAGGCGATGCAGAAGGGGCTCCTGGTGGAGATC
GACCCGATGCAGGCTTACCTGGAGGATCTGGCAACCAAGGTCGATTTCGCCGCCATCGCCAAGTTGGGGACCATCGCCGT
AAATCCTCTCTACGGCACCGCCCGCGGCTACCTCGCCGAACCGCTCAAGGCCCACGGCGTCAAAGTGGTGCAGATGAACG
CCAATCGAGACCCCTACTTCGGCGGATTCCCCCCCGAACCGTCCGAGAAATACATCCAGGACTTCATCCGGCTGGTGCAG
CAGGACCCTTCCATCAGCCTGGGGATCGCCACCGACGGCGACGCGGACCGCTTCGGCATCGTGGATAGCGACGGCAGCTT
CATTGAGCCCAACTACATCATCGCGCTGCTCCTCGATTACCTGGTCCGGGTGAAGGGGATGACCGGCGGGGTAGGGCGCT
CCGTCGCCACCTCGCATCTGGTGGACGCGGTGGCCAAGCTGCACGGGATCGAGGTCTTCGAGACGCCCGTAGGCTTCAAG
TTCATCGGCGAGCTGATCAGCCAGGACAAGATCATCATCGGCGGCGAAGAGAGCGCCGGGCTCACCATCAAGGGGCACGT
CCCCGAAAAGGACGGCATCCTGGCCTGCCTGCTGGTGGCCGAGATGGTCGCGCGCGAAGGCAAGCCGGTGAGGGCTCTGC
TGGAGCAGCTCTACGAGAAGGTGGGGCGCTATCTCACCAAGCGCGTCAACATCACGCTGTCGCCGGAACTGGAAGAAGTC
TTCCCGGAACGCATCGCGGCCACCCCCGCAGGCTTCGCAGGAGTATCGGTAAAGCAGAAGGTGACGGTGGACGGCAACAA
GTTCATCCTGGAGGACGGGAGCTGGCTCCTGTTCAGGAAGTCTGGGACCGAACCGGTGGTGCGGCTTTACGCCGAGGCCT
CCAACGAGGCGCGCCTGCAGGCGCTTTTGGAAGCCGGCCGCGAATTCATCGTGGGCAAAGCGTAA

Upstream 100 bases:

>100_bases
TTTTCAGGTCGCTTGGTGCTGTGATTTCGCCCCCTTCCATCGGGGCGAGCGGGTGTTCGCCTCACCATCTGGTGCCTATT
CAATTCTTTAGGAGGGATTT

Downstream 100 bases:

>100_bases
GCCGGAAGCGTTCCACAATCGACAGCGATGGCGTTTTTTCGCCCCAAGCGAGTCGGGGCGAGTTTAAAAAAAATAAAAAT
GGGACGCGGATGAATCTGAA

Product: phosphoglucomutase/phosphomannomutase family protein

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MQRITFGTSGWRGIMCEDFIFENVKVVTQAIADNVKASGEARKGIIVGYDSRFMGESFAREAARVLTGAGITTYLCIRDT
PTPVIAFEILRRGTAGAINFTASHNPPEYNGIKFSPSWGGPALPQTTTDIENRANEMAGEICYTECSIDEAMQKGLLVEI
DPMQAYLEDLATKVDFAAIAKLGTIAVNPLYGTARGYLAEPLKAHGVKVVQMNANRDPYFGGFPPEPSEKYIQDFIRLVQ
QDPSISLGIATDGDADRFGIVDSDGSFIEPNYIIALLLDYLVRVKGMTGGVGRSVATSHLVDAVAKLHGIEVFETPVGFK
FIGELISQDKIIIGGEESAGLTIKGHVPEKDGILACLLVAEMVAREGKPVRALLEQLYEKVGRYLTKRVNITLSPELEEV
FPERIAATPAGFAGVSVKQKVTVDGNKFILEDGSWLLFRKSGTEPVVRLYAEASNEARLQALLEAGREFIVGKA

Sequences:

>Translated_474_residues
MQRITFGTSGWRGIMCEDFIFENVKVVTQAIADNVKASGEARKGIIVGYDSRFMGESFAREAARVLTGAGITTYLCIRDT
PTPVIAFEILRRGTAGAINFTASHNPPEYNGIKFSPSWGGPALPQTTTDIENRANEMAGEICYTECSIDEAMQKGLLVEI
DPMQAYLEDLATKVDFAAIAKLGTIAVNPLYGTARGYLAEPLKAHGVKVVQMNANRDPYFGGFPPEPSEKYIQDFIRLVQ
QDPSISLGIATDGDADRFGIVDSDGSFIEPNYIIALLLDYLVRVKGMTGGVGRSVATSHLVDAVAKLHGIEVFETPVGFK
FIGELISQDKIIIGGEESAGLTIKGHVPEKDGILACLLVAEMVAREGKPVRALLEQLYEKVGRYLTKRVNITLSPELEEV
FPERIAATPAGFAGVSVKQKVTVDGNKFILEDGSWLLFRKSGTEPVVRLYAEASNEARLQALLEAGREFIVGKA
>Mature_474_residues
MQRITFGTSGWRGIMCEDFIFENVKVVTQAIADNVKASGEARKGIIVGYDSRFMGESFAREAARVLTGAGITTYLCIRDT
PTPVIAFEILRRGTAGAINFTASHNPPEYNGIKFSPSWGGPALPQTTTDIENRANEMAGEICYTECSIDEAMQKGLLVEI
DPMQAYLEDLATKVDFAAIAKLGTIAVNPLYGTARGYLAEPLKAHGVKVVQMNANRDPYFGGFPPEPSEKYIQDFIRLVQ
QDPSISLGIATDGDADRFGIVDSDGSFIEPNYIIALLLDYLVRVKGMTGGVGRSVATSHLVDAVAKLHGIEVFETPVGFK
FIGELISQDKIIIGGEESAGLTIKGHVPEKDGILACLLVAEMVAREGKPVRALLEQLYEKVGRYLTKRVNITLSPELEEV
FPERIAATPAGFAGVSVKQKVTVDGNKFILEDGSWLLFRKSGTEPVVRLYAEASNEARLQALLEAGREFIVGKA

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=494, Percent_Identity=29.3522267206478, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI290463102, Length=520, Percent_Identity=28.6538461538462, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI133922562, Length=473, Percent_Identity=29.3868921775898, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI31377548, Length=542, Percent_Identity=26.1992619926199, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI290463104, Length=332, Percent_Identity=28.9156626506024, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1786904, Length=504, Percent_Identity=30.7539682539683, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1788361, Length=435, Percent_Identity=28.0459770114943, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1789566, Length=460, Percent_Identity=25.8695652173913, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17535441, Length=513, Percent_Identity=27.6803118908382, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71993870, Length=516, Percent_Identity=25.3875968992248, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71993878, Length=115, Percent_Identity=33.0434782608696, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323752, Length=521, Percent_Identity=27.447216890595, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322722, Length=432, Percent_Identity=27.0833333333333, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6323934, Length=407, Percent_Identity=25.3071253071253, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864244, Length=515, Percent_Identity=29.5145631067961, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20129809, Length=554, Percent_Identity=25.2707581227437, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24651977, Length=460, Percent_Identity=26.5217391304348, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 51449; Mature: 51449

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRITFGTSGWRGIMCEDFIFENVKVVTQAIADNVKASGEARKGIIVGYDSRFMGESFAR
CCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHH
EAARVLTGAGITTYLCIRDTPTPVIAFEILRRGTAGAINFTASHNPPEYNGIKFSPSWGG
HHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCCCC
PALPQTTTDIENRANEMAGEICYTECSIDEAMQKGLLVEIDPMQAYLEDLATKVDFAAIA
CCCCCCCHHHHHHHHHHHHHHEEEECCHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHH
KLGTIAVNPLYGTARGYLAEPLKAHGVKVVQMNANRDPYFGGFPPEPSEKYIQDFIRLVQ
HHCCEEECCCCCCCCCHHHCCHHHCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
QDPSISLGIATDGDADRFGIVDSDGSFIEPNYIIALLLDYLVRVKGMTGGVGRSVATSHL
CCCCEEEEEECCCCCCCCCEECCCCCEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VDAVAKLHGIEVFETPVGFKFIGELISQDKIIIGGEESAGLTIKGHVPEKDGILACLLVA
HHHHHHHHCCEEEECCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHH
EMVAREGKPVRALLEQLYEKVGRYLTKRVNITLSPELEEVFPERIAATPAGFAGVSVKQK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEE
VTVDGNKFILEDGSWLLFRKSGTEPVVRLYAEASNEARLQALLEAGREFIVGKA
EEECCCEEEEECCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCHHCCCCC
>Mature Secondary Structure
MQRITFGTSGWRGIMCEDFIFENVKVVTQAIADNVKASGEARKGIIVGYDSRFMGESFAR
CCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHH
EAARVLTGAGITTYLCIRDTPTPVIAFEILRRGTAGAINFTASHNPPEYNGIKFSPSWGG
HHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCCCC
PALPQTTTDIENRANEMAGEICYTECSIDEAMQKGLLVEIDPMQAYLEDLATKVDFAAIA
CCCCCCCHHHHHHHHHHHHHHEEEECCHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHH
KLGTIAVNPLYGTARGYLAEPLKAHGVKVVQMNANRDPYFGGFPPEPSEKYIQDFIRLVQ
HHCCEEECCCCCCCCCHHHCCHHHCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
QDPSISLGIATDGDADRFGIVDSDGSFIEPNYIIALLLDYLVRVKGMTGGVGRSVATSHL
CCCCEEEEEECCCCCCCCCEECCCCCEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VDAVAKLHGIEVFETPVGFKFIGELISQDKIIIGGEESAGLTIKGHVPEKDGILACLLVA
HHHHHHHHCCEEEECCCCHHHHHHHHCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHH
EMVAREGKPVRALLEQLYEKVGRYLTKRVNITLSPELEEVFPERIAATPAGFAGVSVKQK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEE
VTVDGNKFILEDGSWLLFRKSGTEPVVRLYAEASNEARLQALLEAGREFIVGKA
EEECCCEEEEECCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]