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The map label for this gene is aroK-1 [H]

Identifier: 197117942

GI number: 197117942

Start: 1805468

End: 1805980

Strand: Direct

Name: aroK-1 [H]

Synonym: Gbem_1555

Alternate gene names: 197117942

Gene position: 1805468-1805980 (Clockwise)

Preceding gene: 197117941

Following gene: 197117943

Centisome position: 39.12

GC content: 61.4

Gene sequence:

>513_bases
TTGAAGAACAACATCTTTATCACCGGTTTCATGGGGTGCGGCAAGACCAGCGTCGGCCGCGTCCTCTCCCAAAGACTCGG
CTGGACCTTCGTCGATCTGGATCAGGTGATCGTGGACCGGGCGGGTACCAGTATCAAGGAAATCTTCGCTTCAAAGGGAG
AGCCGGCTTTCAGGGCAGTTGAGACCGCCGCACTGGCGGAAGTTGCTTCCCGCCAGTCACAGGTTGTTTCCACCGGCGGC
GGGGCGGTGATCGCGCCACAGAACCGGGAGGCCATGCGAGGCTCGGGCCGCATCGTCAACCTCACCGCGAGCGTCGAGAC
CATCGCCGCGCGCGTAACCGGCGACAGCGAACGCCCTCTTCTCGCCGCTGACGCATCGGTGGAACGGATCAGTTCCATGC
TGCAAGGGCGCGAAGAGTATTATGCCGACGCCGACCTGCGCATCGACACCACGGGCAAGACCATAGAGGCGGTGGCCTCG
GAAGTAATCGACTCTTTGAAGGGGTTTTTGTGA

Upstream 100 bases:

>100_bases
TGAAAGGCCTGTAGATGTAACCTTTAACCAGTTTTTCCTTTGTGACCTCCGTGGACCTCAGTGACCTCTGTGTTCCGATT
ATGGATTTTTTGGGGTTTCT

Downstream 100 bases:

>100_bases
TAGCTGAAAAGATCAGGGTCGCGCTTGACGAACGGAGTTACGACATCGAAATGGGCGCCGGCAATCTCGACAGAATCGGT
TCCCTTTGCCGCGAAGTCGG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MKNNIFITGFMGCGKTSVGRVLSQRLGWTFVDLDQVIVDRAGTSIKEIFASKGEPAFRAVETAALAEVASRQSQVVSTGG
GAVIAPQNREAMRGSGRIVNLTASVETIAARVTGDSERPLLAADASVERISSMLQGREEYYADADLRIDTTGKTIEAVAS
EVIDSLKGFL

Sequences:

>Translated_170_residues
MKNNIFITGFMGCGKTSVGRVLSQRLGWTFVDLDQVIVDRAGTSIKEIFASKGEPAFRAVETAALAEVASRQSQVVSTGG
GAVIAPQNREAMRGSGRIVNLTASVETIAARVTGDSERPLLAADASVERISSMLQGREEYYADADLRIDTTGKTIEAVAS
EVIDSLKGFL
>Mature_170_residues
MKNNIFITGFMGCGKTSVGRVLSQRLGWTFVDLDQVIVDRAGTSIKEIFASKGEPAFRAVETAALAEVASRQSQVVSTGG
GAVIAPQNREAMRGSGRIVNLTASVETIAARVTGDSERPLLAADASVERISSMLQGREEYYADADLRIDTTGKTIEAVAS
EVIDSLKGFL

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=168, Percent_Identity=34.5238095238095, Blast_Score=100, Evalue=4e-23,
Organism=Escherichia coli, GI1786587, Length=174, Percent_Identity=33.9080459770115, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18057; Mature: 18057

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNIFITGFMGCGKTSVGRVLSQRLGWTFVDLDQVIVDRAGTSIKEIFASKGEPAFRAV
CCCCEEEEEECCCCCHHHHHHHHHHHCCEEEHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
ETAALAEVASRQSQVVSTGGGAVIAPQNREAMRGSGRIVNLTASVETIAARVTGDSERPL
HHHHHHHHHHHHHHHEECCCCEEECCCCCHHHCCCCEEEEEEEHHHHHHHHCCCCCCCCE
LAADASVERISSMLQGREEYYADADLRIDTTGKTIEAVASEVIDSLKGFL
EECCCCHHHHHHHHHCHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNNIFITGFMGCGKTSVGRVLSQRLGWTFVDLDQVIVDRAGTSIKEIFASKGEPAFRAV
CCCCEEEEEECCCCCHHHHHHHHHHHCCEEEHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
ETAALAEVASRQSQVVSTGGGAVIAPQNREAMRGSGRIVNLTASVETIAARVTGDSERPL
HHHHHHHHHHHHHHHEECCCCEEECCCCCHHHCCCCEEEEEEEHHHHHHHHCCCCCCCCE
LAADASVERISSMLQGREEYYADADLRIDTTGKTIEAVASEVIDSLKGFL
EECCCCHHHHHHHHHCHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA