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The map label for this gene is mcp046 [H]

Identifier: 197117869

GI number: 197117869

Start: 1717220

End: 1719427

Strand: Reverse

Name: mcp046 [H]

Synonym: Gbem_1482

Alternate gene names: 197117869

Gene position: 1719427-1717220 (Counterclockwise)

Preceding gene: 197117870

Following gene: 197117866

Centisome position: 37.26

GC content: 59.65

Gene sequence:

>2208_bases
ATGTTCGGCAAATTGAAAATCGGGCAGAGAGTGAGTTTGGCGTTCGGCGCGTTACTGCTGCTGATGATTGCTTTGGCGGC
AACGGCCTATTGGGGCATTACCAGTGTCGACCATGAAGTCGTCAAAGCCCTCGACAGTGACGGGGTGATAGCCCAGCATG
CCGGGCGGGCACGCGCCAACATACTGGGGCTGCGCCGTTTTGAGAAGGACATGATACTCAATGTCGCCTCCCCCGAAAAA
GTCGATGAGTACTTCAAAAAATGGCAAGGGCAGGAGGAAAATCTTCAGCAGCGACTGAAGACCCTGGAGCAGGCCGCCAC
CGGGCCGAAGGACCGGCAAGTTGTAAAGGCGATCAGAACCGAAGCGGCCACCTACCGAGACGGCCTCCTCAAGGTGCATG
AAGCGATGGCGAAAGGCGAGATCCGTACCCCTGCACAAGGTAACGCCGCAATCAGCCAGTACAAGGATGCCACCCACAAG
ATGGAAGGCCAAGCGTCGGACTTTGCCACGGACGGGTATGCCCGTCTGGACGGCATCAAAGCGACCATCGGTCAAAAACT
GCAGAAAATAGTGAAGTTACTGGTCATTTTGGTGGCTGTGATCCTGGTGATCGGCGTAGGCACCACCCTCTATCTCTCCA
GAAAGATCGGAAATATCCTGAAATCGCTGATTAAGGAGACGGAAGGACTCACCGAGGCGGCGGTGAGCGGAAATCTCGCC
AGCCGCGGCAATGCGGATAAGATAGATTTCGAGTTCCGCGGGATCATCGTCGGACTGAACCAGACGATGGACGCGGTGAT
AGGGCCACTGAACATGGCGGCCGAGTACGTGGACCGGATCTCCAAGGGGGACATTCCCGCCAAGATAACCGACGACTACA
AGGGTGACTTCAACGAGATAAAACTCAACCTCAACAACTGCATCGACAACGTGAACGCACTGGTCACCGATGCAAACCTG
CTCGCCGAGGCCGCGGTCGCCGGGAGACTCGCCACGCGTGCCGATGCCACCAGGCATAGCGGGGACTTCCGGAAGGTCGT
GGATGGCGTGAACAACACGCTGGACGCGGTTATCGGCCCCCTGAACATGGCCGCCGAGTACGTGGACCGGATCTCCAAAG
GGGACATGCCTCCCGAAATAACCGAAGAGTACCGGGGAGACTTCAACTCGATCAAGCACAACCTGAATGTGCTGATCCAG
GCGACCAACAGCATCACGATCGCAGCGAAGGAGGTTGCGGACGGAAACCTTACCGTACAACTCGCGGAGCGCTCCGGCAG
CGACGAGCTGATGCACGCCCTTTCGAGCATGGTTGCCAAGCTTTCCGAGGTGGTGACCCAGGTGAAGACCGCCTCCGATA
ACGTGGCCGCCGGAAGCCGGCAGATGTCGTCAGGTTCCGAAGAGCTCTCCCAAGGCGCCAGCGAACAGGCTGCCGCCGCC
GAAGAGGCGTCCGCAGCAATGGAGCAGATGACCGCCAACGTCAGGCAGAACGCGGACAACGCCCTGCAGACCGAGAAGAT
CGCGACCAAGTCCGCAACGGACGCACAGCAGGGTGGGGAGGCCGTCGCCGAGACGGTGACGGCGATGAAGGATATTGCCG
GTAAAATCTCCATTATCGAAGAGATCGCCAGGCAGACCAACCTTCTCGCCTTGAACGCCGCCATAGAAGCGGCACGGGCG
GGCGAGCACGGCAAAGGGTTCGCCGTTGTGGCAAGCGAAGTGAGAAAGCTGGCTGAGCGCTCCCAGAAAGCCGCCGCCGA
GATATCGGAGCGCTCCTCCTCCAGCGTCCAGATCGCGGAAAAGGCAGGAGATATGCTGAGCAGGATGCTCCCGGACATCC
AGCGCACGGCCGAACTGGTCCAGGAGATCTCCGCCGCGTGCCGGGAGCAGGACAGCGGAGCCGAACAGATCAACAAGGCG
ATCCAGCAGCTCGACCTGGTGATCCAACAAAACGCCTCAGCAGCCGAAGAGATGTCGTCCACCGCCGAGGAGCTTTCCTC
CCAGTCCGAGCAACTGCAAAGCACCATCGGCTTCTTCAACATCGGTGCAGATCGCACGGCGGGTTCGTTGAAGCAGAACG
TAAAGGCGGGCTCAAAGCCTGCGGCCCCAAAAGCACCTCGGGCCCAAAGCCCTCGCTTGACCCATGCCGGCCCAGCGGGT
GCTGCCTTGGAAATGCACCCGACCGACGCGGAGTACGAGCGTTACTGA

Upstream 100 bases:

>100_bases
GGGCCACCTGGATGATTCGGGAGCTAAATATTCTTCAGTCGATGCATACCGTTGTCAGCTAAGTGCGGGGGTAAGACACC
AAGAAAAAGGGAGACCACAC

Downstream 100 bases:

>100_bases
TCGACACGGATCAGGACACTTCTCATTCAGGCCAGGTTAAAGACAGCCCTTGGCTAAGAAATGCCAGTTCAGAAGGCCTC
CCCCCCTGGGAGGCCTTCTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-II; Aspartate chemoreceptor protein [H]

Number of amino acids: Translated: 735; Mature: 735

Protein sequence:

>735_residues
MFGKLKIGQRVSLAFGALLLLMIALAATAYWGITSVDHEVVKALDSDGVIAQHAGRARANILGLRRFEKDMILNVASPEK
VDEYFKKWQGQEENLQQRLKTLEQAATGPKDRQVVKAIRTEAATYRDGLLKVHEAMAKGEIRTPAQGNAAISQYKDATHK
MEGQASDFATDGYARLDGIKATIGQKLQKIVKLLVILVAVILVIGVGTTLYLSRKIGNILKSLIKETEGLTEAAVSGNLA
SRGNADKIDFEFRGIIVGLNQTMDAVIGPLNMAAEYVDRISKGDIPAKITDDYKGDFNEIKLNLNNCIDNVNALVTDANL
LAEAAVAGRLATRADATRHSGDFRKVVDGVNNTLDAVIGPLNMAAEYVDRISKGDMPPEITEEYRGDFNSIKHNLNVLIQ
ATNSITIAAKEVADGNLTVQLAERSGSDELMHALSSMVAKLSEVVTQVKTASDNVAAGSRQMSSGSEELSQGASEQAAAA
EEASAAMEQMTANVRQNADNALQTEKIATKSATDAQQGGEAVAETVTAMKDIAGKISIIEEIARQTNLLALNAAIEAARA
GEHGKGFAVVASEVRKLAERSQKAAAEISERSSSSVQIAEKAGDMLSRMLPDIQRTAELVQEISAACREQDSGAEQINKA
IQQLDLVIQQNASAAEEMSSTAEELSSQSEQLQSTIGFFNIGADRTAGSLKQNVKAGSKPAAPKAPRAQSPRLTHAGPAG
AALEMHPTDAEYERY

Sequences:

>Translated_735_residues
MFGKLKIGQRVSLAFGALLLLMIALAATAYWGITSVDHEVVKALDSDGVIAQHAGRARANILGLRRFEKDMILNVASPEK
VDEYFKKWQGQEENLQQRLKTLEQAATGPKDRQVVKAIRTEAATYRDGLLKVHEAMAKGEIRTPAQGNAAISQYKDATHK
MEGQASDFATDGYARLDGIKATIGQKLQKIVKLLVILVAVILVIGVGTTLYLSRKIGNILKSLIKETEGLTEAAVSGNLA
SRGNADKIDFEFRGIIVGLNQTMDAVIGPLNMAAEYVDRISKGDIPAKITDDYKGDFNEIKLNLNNCIDNVNALVTDANL
LAEAAVAGRLATRADATRHSGDFRKVVDGVNNTLDAVIGPLNMAAEYVDRISKGDMPPEITEEYRGDFNSIKHNLNVLIQ
ATNSITIAAKEVADGNLTVQLAERSGSDELMHALSSMVAKLSEVVTQVKTASDNVAAGSRQMSSGSEELSQGASEQAAAA
EEASAAMEQMTANVRQNADNALQTEKIATKSATDAQQGGEAVAETVTAMKDIAGKISIIEEIARQTNLLALNAAIEAARA
GEHGKGFAVVASEVRKLAERSQKAAAEISERSSSSVQIAEKAGDMLSRMLPDIQRTAELVQEISAACREQDSGAEQINKA
IQQLDLVIQQNASAAEEMSSTAEELSSQSEQLQSTIGFFNIGADRTAGSLKQNVKAGSKPAAPKAPRAQSPRLTHAGPAG
AALEMHPTDAEYERY
>Mature_735_residues
MFGKLKIGQRVSLAFGALLLLMIALAATAYWGITSVDHEVVKALDSDGVIAQHAGRARANILGLRRFEKDMILNVASPEK
VDEYFKKWQGQEENLQQRLKTLEQAATGPKDRQVVKAIRTEAATYRDGLLKVHEAMAKGEIRTPAQGNAAISQYKDATHK
MEGQASDFATDGYARLDGIKATIGQKLQKIVKLLVILVAVILVIGVGTTLYLSRKIGNILKSLIKETEGLTEAAVSGNLA
SRGNADKIDFEFRGIIVGLNQTMDAVIGPLNMAAEYVDRISKGDIPAKITDDYKGDFNEIKLNLNNCIDNVNALVTDANL
LAEAAVAGRLATRADATRHSGDFRKVVDGVNNTLDAVIGPLNMAAEYVDRISKGDMPPEITEEYRGDFNSIKHNLNVLIQ
ATNSITIAAKEVADGNLTVQLAERSGSDELMHALSSMVAKLSEVVTQVKTASDNVAAGSRQMSSGSEELSQGASEQAAAA
EEASAAMEQMTANVRQNADNALQTEKIATKSATDAQQGGEAVAETVTAMKDIAGKISIIEEIARQTNLLALNAAIEAARA
GEHGKGFAVVASEVRKLAERSQKAAAEISERSSSSVQIAEKAGDMLSRMLPDIQRTAELVQEISAACREQDSGAEQINKA
IQQLDLVIQQNASAAEEMSSTAEELSSQSEQLQSTIGFFNIGADRTAGSLKQNVKAGSKPAAPKAPRAQSPRLTHAGPAG
AALEMHPTDAEYERY

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=342, Percent_Identity=38.5964912280702, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1787690, Length=289, Percent_Identity=40.4844290657439, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI2367378, Length=327, Percent_Identity=37.3088685015291, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1788194, Length=286, Percent_Identity=39.8601398601399, Blast_Score=169, Evalue=7e-43,
Organism=Escherichia coli, GI1789453, Length=294, Percent_Identity=32.9931972789116, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 78493; Mature: 78493

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGKLKIGQRVSLAFGALLLLMIALAATAYWGITSVDHEVVKALDSDGVIAQHAGRARAN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHCCCHHHH
ILGLRRFEKDMILNVASPEKVDEYFKKWQGQEENLQQRLKTLEQAATGPKDRQVVKAIRT
HHHHHHHHHHHHEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EAATYRDGLLKVHEAMAKGEIRTPAQGNAAISQYKDATHKMEGQASDFATDGYARLDGIK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ATIGQKLQKIVKLLVILVAVILVIGVGTTLYLSRKIGNILKSLIKETEGLTEAAVSGNLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
SRGNADKIDFEFRGIIVGLNQTMDAVIGPLNMAAEYVDRISKGDIPAKITDDYKGDFNEI
CCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHE
KLNLNNCIDNVNALVTDANLLAEAAVAGRLATRADATRHSGDFRKVVDGVNNTLDAVIGP
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LNMAAEYVDRISKGDMPPEITEEYRGDFNSIKHNLNVLIQATNSITIAAKEVADGNLTVQ
HHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHCCEEEEEECCCEEEEEHHHCCCCEEEE
LAERSGSDELMHALSSMVAKLSEVVTQVKTASDNVAAGSRQMSSGSEELSQGASEQAAAA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHCCCHHHHHCCCCHHHHHH
EEASAAMEQMTANVRQNADNALQTEKIATKSATDAQQGGEAVAETVTAMKDIAGKISIIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAERSQKAAAEISERSSSSVQIAE
HHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KAGDMLSRMLPDIQRTAELVQEISAACREQDSGAEQINKAIQQLDLVIQQNASAAEEMSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
TAEELSSQSEQLQSTIGFFNIGADRTAGSLKQNVKAGSKPAAPKAPRAQSPRLTHAGPAG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
AALEMHPTDAEYERY
CEEEECCCCCCCCCC
>Mature Secondary Structure
MFGKLKIGQRVSLAFGALLLLMIALAATAYWGITSVDHEVVKALDSDGVIAQHAGRARAN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHCCCHHHH
ILGLRRFEKDMILNVASPEKVDEYFKKWQGQEENLQQRLKTLEQAATGPKDRQVVKAIRT
HHHHHHHHHHHHEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EAATYRDGLLKVHEAMAKGEIRTPAQGNAAISQYKDATHKMEGQASDFATDGYARLDGIK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ATIGQKLQKIVKLLVILVAVILVIGVGTTLYLSRKIGNILKSLIKETEGLTEAAVSGNLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
SRGNADKIDFEFRGIIVGLNQTMDAVIGPLNMAAEYVDRISKGDIPAKITDDYKGDFNEI
CCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHE
KLNLNNCIDNVNALVTDANLLAEAAVAGRLATRADATRHSGDFRKVVDGVNNTLDAVIGP
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LNMAAEYVDRISKGDMPPEITEEYRGDFNSIKHNLNVLIQATNSITIAAKEVADGNLTVQ
HHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHCCEEEEEECCCEEEEEHHHCCCCEEEE
LAERSGSDELMHALSSMVAKLSEVVTQVKTASDNVAAGSRQMSSGSEELSQGASEQAAAA
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHCCCHHHHHCCCCHHHHHH
EEASAAMEQMTANVRQNADNALQTEKIATKSATDAQQGGEAVAETVTAMKDIAGKISIIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAERSQKAAAEISERSSSSVQIAE
HHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KAGDMLSRMLPDIQRTAELVQEISAACREQDSGAEQINKAIQQLDLVIQQNASAAEEMSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
TAEELSSQSEQLQSTIGFFNIGADRTAGSLKQNVKAGSKPAAPKAPRAQSPRLTHAGPAG
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
AALEMHPTDAEYERY
CEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6305515; 9097040; 9278503; 9315712 [H]