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The map label for this gene is tadA [H]

Identifier: 197117867

GI number: 197117867

Start: 1715608

End: 1716045

Strand: Direct

Name: tadA [H]

Synonym: Gbem_1480

Alternate gene names: 197117867

Gene position: 1715608-1716045 (Clockwise)

Preceding gene: 197117864

Following gene: 197117868

Centisome position: 37.17

GC content: 53.65

Gene sequence:

>438_bases
ATGGACATCTATATGCAGTCAGCCATTGAAGAGGCAAAAAAAGGACTTGGGGAAGGGGGTATTCCGATCGGATCGGTGCT
TGTGCATAAAGGGCTCATCCTTGGGCGAGGACACAACCGGCGTGTGCAAAAGGGCAGTTCGATTCTTCACGGAGAAATGG
ACGCGCTGGAAAACGCCGGACGGCTACCGGCGCAGGTCTACCGGGAATCGGTGCTCTATACGACCCTGTCCCCCTGCTCC
ATGTGCAGTGGAGCAATCCTTTTGTATGGGATTCCGCGAGTTGTTATTGGTGAAAACAGCACGTTCACAGGAGAGGAAGA
GTTGCTCCGCTCTCATGGTGTGCAGGTCGATGTGCTGCAGGATCAGGAATGCATCAGCCTGATGCGCACTTTTATCGAGG
AAAAACCTGAGCTGTGGAACGAGGATATCGGGGTGTAG

Upstream 100 bases:

>100_bases
ACAGTGAAAAAGTTAGCTGCCTTGCCTTCAGAAACCCTTCCCTCTCCCGAAAAGGTGAGGAAGGGCGCGCTGAAATATCT
TTAATTGGGAAGGGGGGAGA

Downstream 100 bases:

>100_bases
TGGCATAAGGTGAATATGGCAAGGCAGGACTGGACAATGGCCTTCCTCTGACACTCCCCAATCTGACTTCCACAAACGTC
TTTCCTCTTCTTTTCTGCCG

Product: zinc-dependent cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDIYMQSAIEEAKKGLGEGGIPIGSVLVHKGLILGRGHNRRVQKGSSILHGEMDALENAGRLPAQVYRESVLYTTLSPCS
MCSGAILLYGIPRVVIGENSTFTGEEELLRSHGVQVDVLQDQECISLMRTFIEEKPELWNEDIGV

Sequences:

>Translated_145_residues
MDIYMQSAIEEAKKGLGEGGIPIGSVLVHKGLILGRGHNRRVQKGSSILHGEMDALENAGRLPAQVYRESVLYTTLSPCS
MCSGAILLYGIPRVVIGENSTFTGEEELLRSHGVQVDVLQDQECISLMRTFIEEKPELWNEDIGV
>Mature_145_residues
MDIYMQSAIEEAKKGLGEGGIPIGSVLVHKGLILGRGHNRRVQKGSSILHGEMDALENAGRLPAQVYRESVLYTTLSPCS
MCSGAILLYGIPRVVIGENSTFTGEEELLRSHGVQVDVLQDQECISLMRTFIEEKPELWNEDIGV

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=109, Percent_Identity=33.9449541284404, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=34.2465753424658, Blast_Score=78, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17541138, Length=143, Percent_Identity=31.4685314685315, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=143, Percent_Identity=53.8461538461538, Blast_Score=163, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15898; Mature: 15898

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIYMQSAIEEAKKGLGEGGIPIGSVLVHKGLILGRGHNRRVQKGSSILHGEMDALENAG
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHEECCCCCHHHCCCHHHHHHHHHHHCCC
RLPAQVYRESVLYTTLSPCSMCSGAILLYGIPRVVIGENSTFTGEEELLRSHGVQVDVLQ
CCHHHHHHHHHHHHHCCHHHHHHCHHHHHCCCEEEECCCCCCCCHHHHHHHCCCEEEEEC
DQECISLMRTFIEEKPELWNEDIGV
CHHHHHHHHHHHHHCHHHHCCCCCC
>Mature Secondary Structure
MDIYMQSAIEEAKKGLGEGGIPIGSVLVHKGLILGRGHNRRVQKGSSILHGEMDALENAG
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHEECCCCCHHHCCCHHHHHHHHHHHCCC
RLPAQVYRESVLYTTLSPCSMCSGAILLYGIPRVVIGENSTFTGEEELLRSHGVQVDVLQ
CCHHHHHHHHHHHHHCCHHHHHHCHHHHHCCCEEEECCCCCCCCHHHHHHHCCCEEEEEC
DQECISLMRTFIEEKPELWNEDIGV
CHHHHHHHHHHHHHCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]