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The map label for this gene is crt [H]

Identifier: 197117844

GI number: 197117844

Start: 1687643

End: 1688506

Strand: Direct

Name: crt [H]

Synonym: Gbem_1457

Alternate gene names: 197117844

Gene position: 1687643-1688506 (Clockwise)

Preceding gene: 197117843

Following gene: 308535240

Centisome position: 36.57

GC content: 63.43

Gene sequence:

>864_bases
ATGAAAAGTAGCGCGAGGAATCTGTCGTTGATACCGAATCCCAAGGAGGGTCCGGTCATGCCAAAGCTCAAAGATTGCAC
CCTGACCCTTGAGGATAGGGTCGCCGTACTCACCTTCCAGCGTGACGACGTCCGCAACGCCCTGACCGGAACCGCCCTCA
CCGAAGACATCATCACCACCGTCAACTGGGTCAACAGCGAGGACCGCGTCTCCGTGCTGGTCCTGACCGGCGCAGGGTCC
GCCTTCTCCTCCGGCGGCAACGTGAAGGAGATGCAGTCCCAAAGCGGCACCTTCGAGGGGTCGCCGGTGCAGGTCCAGGA
CAAGTACCGCCGCGGCATCCAGCAGATCCCGCTCGTGCTGCACAAGGCCGAGATCCCGGTCATCGCCGCCGTTAACGGCC
CGGCGATAGGCGCCGGCTTCGACCTCGCCAACATGTGCGACATCCGCCTCGCCTCGACCCGCGCCAAGGTGGGGGAGACC
TTCATCAACCTGGGCATCACCCCCGGTGACGGTGGCGCCTGGTTCATGCAGCGGCTGATGGGTTACCAAAGGGCCGCGGA
GCTCACCTTCACCGGCCGCGTCGTCGAGGCCGCCGAGGCGCTAAAGCTCGGCATCTTCCTGGAGGTTTTGGAGCCGGAAG
AGCTGATGCCGCGCACCATGGAACTCGCGCGCCAGATCGCCTCCAAGCCCCCGGTCACCCTGAGGCTCACCAAGCGGATG
ATGAAACTGGCCCAGAGAAGCGACCTTCCCGACTTCCTCGACCTTTGCGCCTGCTTCCAGTCCCTGGCGCACCACACAGA
CGATCACATCGAGGCGGTGAACGCCTTTTTGGACAAGAGAGATCCGCACTACAAGGGGGAATGA

Upstream 100 bases:

>100_bases
GCCGCCCGATAACTGAGATAGTGCCGGGGGACTGGCTCCGCAGGTGCCTGTCCCCCTTAGCGGTACCCCTCGGATTCACC
AGCAGGTCAGGAGGTTCACC

Downstream 100 bases:

>100_bases
TCTTGTTGACCAGATCGGGAGTCGAACAAGGGAGCGCTCCGGCCCAGGGGGCCGGTTTCATCGACGTGCACACGCACTGC
TTCACCGGCAGCGCCCGGGC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKSSARNLSLIPNPKEGPVMPKLKDCTLTLEDRVAVLTFQRDDVRNALTGTALTEDIITTVNWVNSEDRVSVLVLTGAGS
AFSSGGNVKEMQSQSGTFEGSPVQVQDKYRRGIQQIPLVLHKAEIPVIAAVNGPAIGAGFDLANMCDIRLASTRAKVGET
FINLGITPGDGGAWFMQRLMGYQRAAELTFTGRVVEAAEALKLGIFLEVLEPEELMPRTMELARQIASKPPVTLRLTKRM
MKLAQRSDLPDFLDLCACFQSLAHHTDDHIEAVNAFLDKRDPHYKGE

Sequences:

>Translated_287_residues
MKSSARNLSLIPNPKEGPVMPKLKDCTLTLEDRVAVLTFQRDDVRNALTGTALTEDIITTVNWVNSEDRVSVLVLTGAGS
AFSSGGNVKEMQSQSGTFEGSPVQVQDKYRRGIQQIPLVLHKAEIPVIAAVNGPAIGAGFDLANMCDIRLASTRAKVGET
FINLGITPGDGGAWFMQRLMGYQRAAELTFTGRVVEAAEALKLGIFLEVLEPEELMPRTMELARQIASKPPVTLRLTKRM
MKLAQRSDLPDFLDLCACFQSLAHHTDDHIEAVNAFLDKRDPHYKGE
>Mature_287_residues
MKSSARNLSLIPNPKEGPVMPKLKDCTLTLEDRVAVLTFQRDDVRNALTGTALTEDIITTVNWVNSEDRVSVLVLTGAGS
AFSSGGNVKEMQSQSGTFEGSPVQVQDKYRRGIQQIPLVLHKAEIPVIAAVNGPAIGAGFDLANMCDIRLASTRAKVGET
FINLGITPGDGGAWFMQRLMGYQRAAELTFTGRVVEAAEALKLGIFLEVLEPEELMPRTMELARQIASKPPVTLRLTKRM
MKLAQRSDLPDFLDLCACFQSLAHHTDDHIEAVNAFLDKRDPHYKGE

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=254, Percent_Identity=29.9212598425197, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI4502327, Length=266, Percent_Identity=30.4511278195489, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI31542718, Length=249, Percent_Identity=31.7269076305221, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI70995211, Length=251, Percent_Identity=27.8884462151394, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI68989263, Length=213, Percent_Identity=29.5774647887324, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI45643119, Length=225, Percent_Identity=25.7777777777778, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI260275230, Length=225, Percent_Identity=25.7777777777778, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI260274832, Length=225, Percent_Identity=25.7777777777778, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI116235487, Length=216, Percent_Identity=25.9259259259259, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI20127408, Length=172, Percent_Identity=28.4883720930233, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI221307494, Length=124, Percent_Identity=29.8387096774194, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI213417737, Length=217, Percent_Identity=24.8847926267281, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI221136756, Length=124, Percent_Identity=29.8387096774194, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI221136753, Length=124, Percent_Identity=29.8387096774194, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI157694516, Length=217, Percent_Identity=24.8847926267281, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI25453481, Length=206, Percent_Identity=24.7572815533981, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI51538573, Length=206, Percent_Identity=24.7572815533981, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4757966, Length=206, Percent_Identity=24.7572815533981, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI51538581, Length=206, Percent_Identity=24.7572815533981, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787659, Length=266, Percent_Identity=29.3233082706767, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788597, Length=274, Percent_Identity=29.9270072992701, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=32.9501915708812, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082183, Length=259, Percent_Identity=26.6409266409266, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI221142681, Length=223, Percent_Identity=30.0448430493274, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790281, Length=196, Percent_Identity=29.5918367346939, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788682, Length=132, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=263, Percent_Identity=29.6577946768061, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25145438, Length=257, Percent_Identity=31.1284046692607, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17540714, Length=242, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17535521, Length=282, Percent_Identity=24.468085106383, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=260, Percent_Identity=25, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17558304, Length=182, Percent_Identity=28.021978021978, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=222, Percent_Identity=25.2252252252252, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=207, Percent_Identity=29.4685990338164, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=182, Percent_Identity=27.4725274725275, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=182, Percent_Identity=27.4725274725275, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=182, Percent_Identity=27.4725274725275, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=221, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=262, Percent_Identity=31.6793893129771, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24653477, Length=262, Percent_Identity=31.6793893129771, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24653139, Length=260, Percent_Identity=31.1538461538462, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24654903, Length=219, Percent_Identity=23.7442922374429, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920382, Length=220, Percent_Identity=28.6363636363636, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24650670, Length=249, Percent_Identity=23.6947791164659, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357171, Length=232, Percent_Identity=26.2931034482759, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 31450; Mature: 31450

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSARNLSLIPNPKEGPVMPKLKDCTLTLEDRVAVLTFQRDDVRNALTGTALTEDIITT
CCCCCCCCEECCCCCCCCCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHH
VNWVNSEDRVSVLVLTGAGSAFSSGGNVKEMQSQSGTFEGSPVQVQDKYRRGIQQIPLVL
HHCCCCCCCEEEEEEECCCCHHCCCCCHHHHHHCCCCCCCCCCEEHHHHHCCHHHHHHHE
HKAEIPVIAAVNGPAIGAGFDLANMCDIRLASTRAKVGETFINLGITPGDGGAWFMQRLM
EECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
GYQRAAELTFTGRVVEAAEALKLGIFLEVLEPEELMPRTMELARQIASKPPVTLRLTKRM
HHHHHHHEEECHHHHHHHHHHHHHHHEEECCCHHHCHHHHHHHHHHHCCCCEEHHHHHHH
MKLAQRSDLPDFLDLCACFQSLAHHTDDHIEAVNAFLDKRDPHYKGE
HHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKSSARNLSLIPNPKEGPVMPKLKDCTLTLEDRVAVLTFQRDDVRNALTGTALTEDIITT
CCCCCCCCEECCCCCCCCCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHH
VNWVNSEDRVSVLVLTGAGSAFSSGGNVKEMQSQSGTFEGSPVQVQDKYRRGIQQIPLVL
HHCCCCCCCEEEEEEECCCCHHCCCCCHHHHHHCCCCCCCCCCEEHHHHHCCHHHHHHHE
HKAEIPVIAAVNGPAIGAGFDLANMCDIRLASTRAKVGETFINLGITPGDGGAWFMQRLM
EECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
GYQRAAELTFTGRVVEAAEALKLGIFLEVLEPEELMPRTMELARQIASKPPVTLRLTKRM
HHHHHHHEEECHHHHHHHHHHHHHHHEEECCCHHHCHHHHHHHHHHHCCCCEEHHHHHHH
MKLAQRSDLPDFLDLCACFQSLAHHTDDHIEAVNAFLDKRDPHYKGE
HHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]