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The map label for this gene is cat2 [H]

Identifier: 197117826

GI number: 197117826

Start: 1662826

End: 1664139

Strand: Direct

Name: cat2 [H]

Synonym: Gbem_1439

Alternate gene names: 197117826

Gene position: 1662826-1664139 (Clockwise)

Preceding gene: 197117825

Following gene: 197117829

Centisome position: 36.03

GC content: 62.63

Gene sequence:

>1314_bases
GTGAATACTATCGCCCTTGCAAAAAGCAACTTCGAACAGGAATACCGGCAAAAACTCTGCTCGGCTGCCGAAGCTGCCAC
CATTGTCAAATCGGGAGATCACCTCTGCTTTCCACTGGGCGTAGGCGAGCCGACCTTGTTCGTCAAGGCGCTCGCGGCAC
GAAAGCGTGAGCTCGAAGGTGTGGTGGTGAACCAGCAGCATCATCTCTGCCCCGACTACTTCACCGAGGACTCCACCCCG
CACATCAAGGTCAACGCGTGGTTCACCAGCCACGTGTCGCGCGAAGCGGTGCAGAAGGGTTGGGCGGACTTCGTCCCCAA
CCACTTCCACGAAGTGCCCAAGCTGCTGCGCGAGTACTGGCCGGTCGACGTCGCCGGAACCGTGGTCTCCCCGATGGACG
AGTACGGCTACTTCACCTGCAGCCTCTCGGTCGGCTACACCATGGAGGCGGTGAAGAAGGCGGAGAAGGTGGTGGTTCAG
GTCAACCCCAACGCGCCGCGCACCCACGGCAACTGTCACATCCACATCTCCGAGGTGGACCACATCATCGAGTGCCATGA
GCCGCTCAAGGAACTGGAAATCCCCAAGATTTCACCGATCGAGGAAGCCATCGGCGCTTACCTCGCCGAGATGGTTCCCG
ACGGCTCCTGTCTGCAGCTAGGCTGGGGCGGCATCCCCAACGCGGTCACCCGCGCGCTCATGACCAAGAAGGACCTGGGC
GTCCACACCGAACTCATGTCCGACGGGATCGTGGACCTGATGCTGTCCGGCGCGGTCAACAACTCCAGGAAGACCATCCA
CCGCGGCAAGGCCTTGGCGACCTTTGCGCTCGGGACCAAGCGCCTGTTCGACTTCATGCACGAGAACCCGATGATCGAGA
TGCACCCGGTCGACTACGTGAACGACCCGGCCGTGATCGGGAGCATCGACAACGTGGTCGCCATCAACGCCACCATCCAG
GTCGATCTCTTGGGGCAGTGCTGTTCCGAGTCCTTCGGGCACCTGCAGTGGAGCGGGACCGGCGGACAGGCCGACTTCGC
GCGCGGCGCCAACAGGTCGCGCGGCGGCAAGGCCTTCATCACCACCGCCTCCACCGCGAAAAACGGCACCATCTCCTGCA
TCGTGCCGACGCTCACCGCGGGTGCCTCCGTCACCACCAGCAAGAACGACGTGGACCACGTCGTGACCGAGTTCGGCGTC
GCTAAGCTCAGGGGGCAGACCGCGAAGCAGCGCGCCATGAACCTGATCAACGTGGCGCACCCGGACTTCCGCGGCGAGCT
GATGGAAGCGGCTCGCAGGATGAATAGGATTTAG

Upstream 100 bases:

>100_bases
AGGAAATCCGGATTTTGGTACCCAAGTTGCTATTAACCTTCTCCAGAAGCAGCCCGCAGGCAAGGCCGCACACAACAACC
ACAAACAGGAGGAAGCACCC

Downstream 100 bases:

>100_bases
CTGGAAAAGGGGGGGGGTAGGGAAGCAGGCGCCTTTCAGTTCCCCCTCCACCTGCGGGAGGGGGGACTGAGGAGGAGATG
AGAGCGGTTGAGGGGGCGGG

Product: acyl-CoA--carboxylate CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNTIALAKSNFEQEYRQKLCSAAEAATIVKSGDHLCFPLGVGEPTLFVKALAARKRELEGVVVNQQHHLCPDYFTEDSTP
HIKVNAWFTSHVSREAVQKGWADFVPNHFHEVPKLLREYWPVDVAGTVVSPMDEYGYFTCSLSVGYTMEAVKKAEKVVVQ
VNPNAPRTHGNCHIHISEVDHIIECHEPLKELEIPKISPIEEAIGAYLAEMVPDGSCLQLGWGGIPNAVTRALMTKKDLG
VHTELMSDGIVDLMLSGAVNNSRKTIHRGKALATFALGTKRLFDFMHENPMIEMHPVDYVNDPAVIGSIDNVVAINATIQ
VDLLGQCCSESFGHLQWSGTGGQADFARGANRSRGGKAFITTASTAKNGTISCIVPTLTAGASVTTSKNDVDHVVTEFGV
AKLRGQTAKQRAMNLINVAHPDFRGELMEAARRMNRI

Sequences:

>Translated_437_residues
MNTIALAKSNFEQEYRQKLCSAAEAATIVKSGDHLCFPLGVGEPTLFVKALAARKRELEGVVVNQQHHLCPDYFTEDSTP
HIKVNAWFTSHVSREAVQKGWADFVPNHFHEVPKLLREYWPVDVAGTVVSPMDEYGYFTCSLSVGYTMEAVKKAEKVVVQ
VNPNAPRTHGNCHIHISEVDHIIECHEPLKELEIPKISPIEEAIGAYLAEMVPDGSCLQLGWGGIPNAVTRALMTKKDLG
VHTELMSDGIVDLMLSGAVNNSRKTIHRGKALATFALGTKRLFDFMHENPMIEMHPVDYVNDPAVIGSIDNVVAINATIQ
VDLLGQCCSESFGHLQWSGTGGQADFARGANRSRGGKAFITTASTAKNGTISCIVPTLTAGASVTTSKNDVDHVVTEFGV
AKLRGQTAKQRAMNLINVAHPDFRGELMEAARRMNRI
>Mature_437_residues
MNTIALAKSNFEQEYRQKLCSAAEAATIVKSGDHLCFPLGVGEPTLFVKALAARKRELEGVVVNQQHHLCPDYFTEDSTP
HIKVNAWFTSHVSREAVQKGWADFVPNHFHEVPKLLREYWPVDVAGTVVSPMDEYGYFTCSLSVGYTMEAVKKAEKVVVQ
VNPNAPRTHGNCHIHISEVDHIIECHEPLKELEIPKISPIEEAIGAYLAEMVPDGSCLQLGWGGIPNAVTRALMTKKDLG
VHTELMSDGIVDLMLSGAVNNSRKTIHRGKALATFALGTKRLFDFMHENPMIEMHPVDYVNDPAVIGSIDNVVAINATIQ
VDLLGQCCSESFGHLQWSGTGGQADFARGANRSRGGKAFITTASTAKNGTISCIVPTLTAGASVTTSKNDVDHVVTEFGV
AKLRGQTAKQRAMNLINVAHPDFRGELMEAARRMNRI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=464, Percent_Identity=24.1379310344828, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32563853, Length=427, Percent_Identity=38.4074941451991, Blast_Score=269, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17538151, Length=426, Percent_Identity=34.5070422535211, Blast_Score=233, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6319456, Length=399, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21358615, Length=415, Percent_Identity=40, Blast_Score=281, Evalue=7e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 47767; Mature: 47767

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIALAKSNFEQEYRQKLCSAAEAATIVKSGDHLCFPLGVGEPTLFVKALAARKRELEG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
VVVNQQHHLCPDYFTEDSTPHIKVNAWFTSHVSREAVQKGWADFVPNHFHEVPKLLREYW
EEECCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHC
PVDVAGTVVSPMDEYGYFTCSLSVGYTMEAVKKAEKVVVQVNPNAPRTHGNCHIHISEVD
CCCCCCHHHCCHHHCCEEEEEEECCCHHHHHHHHHEEEEEECCCCCCCCCCEEEEHHHHH
HIIECHEPLKELEIPKISPIEEAIGAYLAEMVPDGSCLQLGWGGIPNAVTRALMTKKDLG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCC
VHTELMSDGIVDLMLSGAVNNSRKTIHRGKALATFALGTKRLFDFMHENPMIEMHPVDYV
CHHHHHHCCHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
NDPAVIGSIDNVVAINATIQVDLLGQCCSESFGHLQWSGTGGQADFARGANRSRGGKAFI
CCCCEEECCCCEEEEEEEEEEEHHHHHHHHHCCCEEECCCCCCCHHHCCCCCCCCCEEEE
TTASTAKNGTISCIVPTLTAGASVTTSKNDVDHVVTEFGVAKLRGQTAKQRAMNLINVAH
EECCCCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
PDFRGELMEAARRMNRI
CCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTIALAKSNFEQEYRQKLCSAAEAATIVKSGDHLCFPLGVGEPTLFVKALAARKRELEG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
VVVNQQHHLCPDYFTEDSTPHIKVNAWFTSHVSREAVQKGWADFVPNHFHEVPKLLREYW
EEECCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHC
PVDVAGTVVSPMDEYGYFTCSLSVGYTMEAVKKAEKVVVQVNPNAPRTHGNCHIHISEVD
CCCCCCHHHCCHHHCCEEEEEEECCCHHHHHHHHHEEEEEECCCCCCCCCCEEEEHHHHH
HIIECHEPLKELEIPKISPIEEAIGAYLAEMVPDGSCLQLGWGGIPNAVTRALMTKKDLG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCC
VHTELMSDGIVDLMLSGAVNNSRKTIHRGKALATFALGTKRLFDFMHENPMIEMHPVDYV
CHHHHHHCCHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
NDPAVIGSIDNVVAINATIQVDLLGQCCSESFGHLQWSGTGGQADFARGANRSRGGKAFI
CCCCEEECCCCEEEEEEEEEEEHHHHHHHHHCCCEEECCCCCCCHHHCCCCCCCCCEEEE
TTASTAKNGTISCIVPTLTAGASVTTSKNDVDHVVTEFGVAKLRGQTAKQRAMNLINVAH
EECCCCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
PDFRGELMEAARRMNRI
CCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]