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The map label for this gene is bcrB [H]

Identifier: 197117801

GI number: 197117801

Start: 1628347

End: 1629594

Strand: Direct

Name: bcrB [H]

Synonym: Gbem_1413

Alternate gene names: 197117801

Gene position: 1628347-1629594 (Clockwise)

Preceding gene: 197117800

Following gene: 308535238

Centisome position: 35.28

GC content: 63.78

Gene sequence:

>1248_bases
ATGAAAGAAGAAACCAAGCTGGCGAGGAAGAAGATAGAGGCCACTAGCCTAATGAACAGGATCATGGCCGACTATTTTCT
GGACCTGAACCAGGCGTCCGCCAGCAACAGCCGCAAGGTCGCCTGGTGCACGAGCGTAGGCCCCGCCGAACTCTTGAGGG
CCATGGGCTTTGCGGTGCACTTCCCGGAAAACCACGCCGCCATGCTGGGGGCGACGCGTCTTGCCACCGACCTGATCCCG
GAGGCGAACGCCATAGGGTATTCGCCCGACATCTGCTCCTACCTCACCTCCGATCTCGGCGCCTACCTCAAAGGCTTCAC
CCCGCTCGCCAAGGCCTACCCCGGCATAGCGGCGGTCCCCAAGCCCGACGTGCTGGTCTACAACACCAACCAGTGCCGCG
ACGTACAGGACTGGTTCGCCTGGTACGCCCGGGAGCTGGGGGTGCCGTTGATCGGTATCACCTCGCCTAAGAACGTGAAC
GAGGTGACCGAGGCCCACGTGGAGGACGTGACGAGGCAGTTGGAGGCGCTGGTCCCGGTACTGGAGGGGATCGCCGGCGC
GCCGCTCGACCTCGCGCGGCTTAAGGAAGTGGTCGCTCTCTCGCGCGACTGCACCGAACTCTGGAAAGAGGTCCTGGAGA
CTGCCACGGCGGTCCCAGCGCCCCTTACCTTCTTCGACGGGACCATCCACATGGGGCCGGCCGTGGTGCTCCGGGGGACG
CCGCAGGCGGTCGAGTACTACCGGGTGCTCCTGGCCGAGTTGGAGCAGAGAAAGGCTACGCGGGAAGCTGCGGTTGCCGG
CGAGGAATACCGCATCTACTGGGACGGCATGCCGGTGTGGGGGCGCCTCAGGCCGCACTCCGAGCTCTTCGCGGGGCTTA
AGACCAACGTGGTCGCCTCCACCTACTGCTCCAGCTGGATCTTCCCGGCCTTCGACGCCGAAGAGCCGCTGCGCAGCATG
GCCAAGGCGTACCTGGAACTCTTCATCGTCCGCTCCGACGCCTACAAGGAGCGCTACCTGGCCGATATGACGAAGAAATT
CCGCATCGACGGGATCGTCTACCACGACGCCAAAACCTGCCCCTACAACTCCAACAGCCGCTACGGCATGCCGCAGCGCC
TGGAGGCGGAGACGGGGCTGCCGTACCTGGTCATCTCCGGCGATCTCAACGACATGCGCTGCGTCTCCGACGAACAGACC
AAGACCAACGTGGAAGCATTCATCGAACAACTCGAGGAGGGGAAATGA

Upstream 100 bases:

>100_bases
TCCCCAAACTCCCGCAACTGGCAGGGGCCGTCGGCGCCGCCCTCTACGCCAGGGCGGGAGAAGCCGCCGCCGTACCGCAA
CCGCTGCTAAGGAGAGTGAA

Downstream 100 bases:

>100_bases
CCATGCTGGACTCACTTTTCAAGCCCAAGGCCGTCGCCATCGTCGGCGCCTCCACCAAGGAACTCTCCATAGGGAACGTC
ATCATTCGCAACCTGCAGCG

Product: hydroxyacyl/enoyl-CoA dehydratase/reductase

Products: NA

Alternate protein names: 3-hydroxybenzoyl-CoA reductase subunit beta [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MKEETKLARKKIEATSLMNRIMADYFLDLNQASASNSRKVAWCTSVGPAELLRAMGFAVHFPENHAAMLGATRLATDLIP
EANAIGYSPDICSYLTSDLGAYLKGFTPLAKAYPGIAAVPKPDVLVYNTNQCRDVQDWFAWYARELGVPLIGITSPKNVN
EVTEAHVEDVTRQLEALVPVLEGIAGAPLDLARLKEVVALSRDCTELWKEVLETATAVPAPLTFFDGTIHMGPAVVLRGT
PQAVEYYRVLLAELEQRKATREAAVAGEEYRIYWDGMPVWGRLRPHSELFAGLKTNVVASTYCSSWIFPAFDAEEPLRSM
AKAYLELFIVRSDAYKERYLADMTKKFRIDGIVYHDAKTCPYNSNSRYGMPQRLEAETGLPYLVISGDLNDMRCVSDEQT
KTNVEAFIEQLEEGK

Sequences:

>Translated_415_residues
MKEETKLARKKIEATSLMNRIMADYFLDLNQASASNSRKVAWCTSVGPAELLRAMGFAVHFPENHAAMLGATRLATDLIP
EANAIGYSPDICSYLTSDLGAYLKGFTPLAKAYPGIAAVPKPDVLVYNTNQCRDVQDWFAWYARELGVPLIGITSPKNVN
EVTEAHVEDVTRQLEALVPVLEGIAGAPLDLARLKEVVALSRDCTELWKEVLETATAVPAPLTFFDGTIHMGPAVVLRGT
PQAVEYYRVLLAELEQRKATREAAVAGEEYRIYWDGMPVWGRLRPHSELFAGLKTNVVASTYCSSWIFPAFDAEEPLRSM
AKAYLELFIVRSDAYKERYLADMTKKFRIDGIVYHDAKTCPYNSNSRYGMPQRLEAETGLPYLVISGDLNDMRCVSDEQT
KTNVEAFIEQLEEGK
>Mature_415_residues
MKEETKLARKKIEATSLMNRIMADYFLDLNQASASNSRKVAWCTSVGPAELLRAMGFAVHFPENHAAMLGATRLATDLIP
EANAIGYSPDICSYLTSDLGAYLKGFTPLAKAYPGIAAVPKPDVLVYNTNQCRDVQDWFAWYARELGVPLIGITSPKNVN
EVTEAHVEDVTRQLEALVPVLEGIAGAPLDLARLKEVVALSRDCTELWKEVLETATAVPAPLTFFDGTIHMGPAVVLRGT
PQAVEYYRVLLAELEQRKATREAAVAGEEYRIYWDGMPVWGRLRPHSELFAGLKTNVVASTYCSSWIFPAFDAEEPLRSM
AKAYLELFIVRSDAYKERYLADMTKKFRIDGIVYHDAKTCPYNSNSRYGMPQRLEAETGLPYLVISGDLNDMRCVSDEQT
KTNVEAFIEQLEEGK

Specific function: Catalyzes the anaerobic reduction of benzoyl-CoA and 3- hydroxybenzoyl-CoA to form cyclohexa-1,5-diene-1-carbonyl-CoA and 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA, respectively. The enzyme also reduces other benzoyl-CoA analogs with small substituents

COG id: COG1775

COG function: function code E; Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011955
- InterPro:   IPR010327 [H]

Pfam domain/function: PF06050 HGD-D [H]

EC number: =1.3.99.15 [H]

Molecular weight: Translated: 46240; Mature: 46240

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEETKLARKKIEATSLMNRIMADYFLDLNQASASNSRKVAWCTSVGPAELLRAMGFAVH
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEECCCCHHHHHHHCCCEEE
FPENHAAMLGATRLATDLIPEANAIGYSPDICSYLTSDLGAYLKGFTPLAKAYPGIAAVP
CCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
KPDVLVYNTNQCRDVQDWFAWYARELGVPLIGITSPKNVNEVTEAHVEDVTRQLEALVPV
CCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LEGIAGAPLDLARLKEVVALSRDCTELWKEVLETATAVPAPLTFFDGTIHMGPAVVLRGT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEECCCEEEEECC
PQAVEYYRVLLAELEQRKATREAAVAGEEYRIYWDGMPVWGRLRPHSELFAGLKTNVVAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
TYCSSWIFPAFDAEEPLRSMAKAYLELFIVRSDAYKERYLADMTKKFRIDGIVYHDAKTC
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECEEEEECCCCC
PYNSNSRYGMPQRLEAETGLPYLVISGDLNDMRCVSDEQTKTNVEAFIEQLEEGK
CCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEETKLARKKIEATSLMNRIMADYFLDLNQASASNSRKVAWCTSVGPAELLRAMGFAVH
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCEEEEECCCCHHHHHHHCCCEEE
FPENHAAMLGATRLATDLIPEANAIGYSPDICSYLTSDLGAYLKGFTPLAKAYPGIAAVP
CCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
KPDVLVYNTNQCRDVQDWFAWYARELGVPLIGITSPKNVNEVTEAHVEDVTRQLEALVPV
CCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LEGIAGAPLDLARLKEVVALSRDCTELWKEVLETATAVPAPLTFFDGTIHMGPAVVLRGT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEECCCEEEEECC
PQAVEYYRVLLAELEQRKATREAAVAGEEYRIYWDGMPVWGRLRPHSELFAGLKTNVVAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
TYCSSWIFPAFDAEEPLRSMAKAYLELFIVRSDAYKERYLADMTKKFRIDGIVYHDAKTC
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECEEEEECCCCC
PYNSNSRYGMPQRLEAETGLPYLVISGDLNDMRCVSDEQTKTNVEAFIEQLEEGK
CCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9746358; 11208796 [H]