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The map label for this gene is mcp035 [H]

Identifier: 197117434

GI number: 197117434

Start: 1216067

End: 1217821

Strand: Reverse

Name: mcp035 [H]

Synonym: Gbem_1044

Alternate gene names: 197117434

Gene position: 1217821-1216067 (Counterclockwise)

Preceding gene: 197117435

Following gene: 197117433

Centisome position: 26.39

GC content: 64.27

Gene sequence:

>1755_bases
ATGAAAGCGACCGCGTTCAGGGACTGGAAAATTTTGACCAAGATTCTCAGCATTTCCGTGGCGACCATCGTGATGATGGT
GCTGGGGGTGATGTTCTACGTGCTCCCCTTCGTGCAGAACAAGCTGATGAACGAGAAGATCGGCGCCACGAAGGCCGTGG
TGGACGTAGCCTACGACGTCCTGACCGAAAACTACAACTCCTACAAGGCGGGGGCCAAGACCCTGCAGCAGGCGCAGGCC
GACGCCCTGAAGCAGATCGCCGAGATGCGCTATCAGGGGAACGAGTACTTCTGGGTCAACGACCTCGACACCAAGGTGCT
GATGCACCCCATCAAGCCGGAGATGGTCGGCAAGACCCAGTACGACAACAAGGACCCCAACGGCAAGAAGCTCTACGTCG
AGTTCGTCAACGTCTGCAAGGAGAAGGGCGAAGGGGTGGTGGACTACATGTGGGCCAAGCCCGGCTCCACGGTCCCGGTC
CCGAAGATCTCCTACGTGATGCTGATGAAGGAGTGGGGCTGGATCGTGGGAAGCGGCATCTACGTCGACAACGTGACCGC
CGAGATGAACAAGATGAAGTGGCAGATCATCGGCGCGACCTTCGGGCTGTCGCTCGTCATCTTCGCCTTCGCCTGGTTCG
TGGCGAGGAAGATCAAGGAGGCGCTGGACCTGGCCATCGCCGCTTCGAAGCGGATCGCCGCGGGCGACCTCACCGCCCAC
ATCGAGGTGAAGAGCAAGGACGAGACCGGGGAACTTCTCGGTTCGCTCGCCGAGATGAACGAGGGTCTCGCCCGCATCGT
GGGTGAGGTGAGAAACGGCGCCGAATCGATCGCCACTGCGACCGAGGAGATAGCGGCAGGCAACGCCGACCTCTCTCAAC
GCACCGAGGAGCAGGCAAGCGCCCTGGAGGAGACCGCCTCCAGCATGGAAGAGCTCACCTCCACGGTGAAGCAGAACGCT
GACAACGCCCAGGCCGCGAACCAGCTCGCCATCAACGCCAGCGGCGTCGCGGTCAAGGGGGGCGAGGTGATCAACCGGGT
GGTCACCACCATGGAGTCGATCACGGACAGCTCCAAGAAGATCTCCGACATCATAGGGGTCATCGACGGCATCGCCTTCC
AGACCAACATCCTGGCCTTGAACGCCGCCGTCGAGGCGGCGCGCGCGGGAGAGCAGGGGAGAGGCTTCGCCGTGGTCGCG
GCCGAGGTGAGGAGCCTGGCGCAGCGAAGCGCCGCTGCGGCCAAGGAGATCAAGGCCCTGATCGAGGACTCGGTGGGGAA
GGTCCAGGACGGCAGCCGCCTGGTCGAGGAGGCCGGGCGCACCACCCAGGACATCGTCACCAGCATCAAGCGGGTGACCG
ACATCATGGCGGAGATCTCCGCCGCCTCGCTGGAGCAGTCCAGCGGCATCGAGCAGGTGAACACGGCCATCACCCAGATG
GACGACGTGACCCAGCAGAACGCGGCGCTGGTCGAGGAGGCCGCTGCCGCCGCGGAATCGCTCGAAGAGCAGGCCCAGCA
GCTGGTGCAGGTGGTGGCCCGCTTCACCCTGGAAAGCTCGCCCAAGGCCCAGGCGCCCGCGGAGAAGCGCAAGGCCGCTG
CCGGCCTTGCGGCCAGGCAGAAGGCCCCCGAGAAAAAAGGAAGGGCGCTCACCGCGGCGGGGGTAAAGCCGCGGGAACAG
CGGCCGGTCAAGGCGGCTGCGGCTGCCGCGACGGCCGAGGTAGCCGAGCTTGACGACGATTGGAAGGAATTCTGA

Upstream 100 bases:

>100_bases
AGATGCTCATCCTGGTGGATATCGAGAAGCTGATCGGCAGCGAGGAGCTGCAGATCGTGGACCATAGCACGGAAAACATT
CAAAAAGAGGTGGTGAACAT

Downstream 100 bases:

>100_bases
GAACGCAGCAGGAAAAAAGCGTGGAGCGGCGCTTTTCGGGAGGGGGGTTCGCCTCCCTCCCGGATGCGTTCCACTACACG
CTTACCGATGACGACTTCGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-II; Aspartate chemoreceptor protein [H]

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MKATAFRDWKILTKILSISVATIVMMVLGVMFYVLPFVQNKLMNEKIGATKAVVDVAYDVLTENYNSYKAGAKTLQQAQA
DALKQIAEMRYQGNEYFWVNDLDTKVLMHPIKPEMVGKTQYDNKDPNGKKLYVEFVNVCKEKGEGVVDYMWAKPGSTVPV
PKISYVMLMKEWGWIVGSGIYVDNVTAEMNKMKWQIIGATFGLSLVIFAFAWFVARKIKEALDLAIAASKRIAAGDLTAH
IEVKSKDETGELLGSLAEMNEGLARIVGEVRNGAESIATATEEIAAGNADLSQRTEEQASALEETASSMEELTSTVKQNA
DNAQAANQLAINASGVAVKGGEVINRVVTTMESITDSSKKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
AEVRSLAQRSAAAAKEIKALIEDSVGKVQDGSRLVEEAGRTTQDIVTSIKRVTDIMAEISAASLEQSSGIEQVNTAITQM
DDVTQQNAALVEEAAAAAESLEEQAQQLVQVVARFTLESSPKAQAPAEKRKAAAGLAARQKAPEKKGRALTAAGVKPREQ
RPVKAAAAAATAEVAELDDDWKEF

Sequences:

>Translated_584_residues
MKATAFRDWKILTKILSISVATIVMMVLGVMFYVLPFVQNKLMNEKIGATKAVVDVAYDVLTENYNSYKAGAKTLQQAQA
DALKQIAEMRYQGNEYFWVNDLDTKVLMHPIKPEMVGKTQYDNKDPNGKKLYVEFVNVCKEKGEGVVDYMWAKPGSTVPV
PKISYVMLMKEWGWIVGSGIYVDNVTAEMNKMKWQIIGATFGLSLVIFAFAWFVARKIKEALDLAIAASKRIAAGDLTAH
IEVKSKDETGELLGSLAEMNEGLARIVGEVRNGAESIATATEEIAAGNADLSQRTEEQASALEETASSMEELTSTVKQNA
DNAQAANQLAINASGVAVKGGEVINRVVTTMESITDSSKKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
AEVRSLAQRSAAAAKEIKALIEDSVGKVQDGSRLVEEAGRTTQDIVTSIKRVTDIMAEISAASLEQSSGIEQVNTAITQM
DDVTQQNAALVEEAAAAAESLEEQAQQLVQVVARFTLESSPKAQAPAEKRKAAAGLAARQKAPEKKGRALTAAGVKPREQ
RPVKAAAAAATAEVAELDDDWKEF
>Mature_584_residues
MKATAFRDWKILTKILSISVATIVMMVLGVMFYVLPFVQNKLMNEKIGATKAVVDVAYDVLTENYNSYKAGAKTLQQAQA
DALKQIAEMRYQGNEYFWVNDLDTKVLMHPIKPEMVGKTQYDNKDPNGKKLYVEFVNVCKEKGEGVVDYMWAKPGSTVPV
PKISYVMLMKEWGWIVGSGIYVDNVTAEMNKMKWQIIGATFGLSLVIFAFAWFVARKIKEALDLAIAASKRIAAGDLTAH
IEVKSKDETGELLGSLAEMNEGLARIVGEVRNGAESIATATEEIAAGNADLSQRTEEQASALEETASSMEELTSTVKQNA
DNAQAANQLAINASGVAVKGGEVINRVVTTMESITDSSKKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
AEVRSLAQRSAAAAKEIKALIEDSVGKVQDGSRLVEEAGRTTQDIVTSIKRVTDIMAEISAASLEQSSGIEQVNTAITQM
DDVTQQNAALVEEAAAAAESLEEQAQQLVQVVARFTLESSPKAQAPAEKRKAAAGLAARQKAPEKKGRALTAAGVKPREQ
RPVKAAAAAATAEVAELDDDWKEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=541, Percent_Identity=43.6229205175601, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI2367378, Length=362, Percent_Identity=56.6298342541437, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1787690, Length=338, Percent_Identity=57.1005917159763, Blast_Score=316, Evalue=3e-87,
Organism=Escherichia coli, GI1788194, Length=335, Percent_Identity=54.0298507462687, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1789453, Length=300, Percent_Identity=41, Blast_Score=228, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62786; Mature: 62786

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATAFRDWKILTKILSISVATIVMMVLGVMFYVLPFVQNKLMNEKIGATKAVVDVAYDV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LTENYNSYKAGAKTLQQAQADALKQIAEMRYQGNEYFWVNDLDTKVLMHPIKPEMVGKTQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCHHHCCCCC
YDNKDPNGKKLYVEFVNVCKEKGEGVVDYMWAKPGSTVPVPKISYVMLMKEWGWIVGSGI
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHEECCE
YVDNVTAEMNKMKWQIIGATFGLSLVIFAFAWFVARKIKEALDLAIAASKRIAAGDLTAH
EEECCHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEE
IEVKSKDETGELLGSLAEMNEGLARIVGEVRNGAESIATATEEIAAGNADLSQRTEEQAS
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ALEETASSMEELTSTVKQNADNAQAANQLAINASGVAVKGGEVINRVVTTMESITDSSKK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCEECCHHHHHHHHHHHHHHHCHHHH
ISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRSLAQRSAAAAKEIKAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IEDSVGKVQDGSRLVEEAGRTTQDIVTSIKRVTDIMAEISAASLEQSSGIEQVNTAITQM
HHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DDVTQQNAALVEEAAAAAESLEEQAQQLVQVVARFTLESSPKAQAPAEKRKAAAGLAARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KAPEKKGRALTAAGVKPREQRPVKAAAAAATAEVAELDDDWKEF
CCCHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MKATAFRDWKILTKILSISVATIVMMVLGVMFYVLPFVQNKLMNEKIGATKAVVDVAYDV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LTENYNSYKAGAKTLQQAQADALKQIAEMRYQGNEYFWVNDLDTKVLMHPIKPEMVGKTQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCHHHCCCCC
YDNKDPNGKKLYVEFVNVCKEKGEGVVDYMWAKPGSTVPVPKISYVMLMKEWGWIVGSGI
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCHHEECCE
YVDNVTAEMNKMKWQIIGATFGLSLVIFAFAWFVARKIKEALDLAIAASKRIAAGDLTAH
EEECCHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCEEE
IEVKSKDETGELLGSLAEMNEGLARIVGEVRNGAESIATATEEIAAGNADLSQRTEEQAS
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ALEETASSMEELTSTVKQNADNAQAANQLAINASGVAVKGGEVINRVVTTMESITDSSKK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEECCCCEECCHHHHHHHHHHHHHHHCHHHH
ISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRSLAQRSAAAAKEIKAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IEDSVGKVQDGSRLVEEAGRTTQDIVTSIKRVTDIMAEISAASLEQSSGIEQVNTAITQM
HHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DDVTQQNAALVEEAAAAAESLEEQAQQLVQVVARFTLESSPKAQAPAEKRKAAAGLAARQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KAPEKKGRALTAAGVKPREQRPVKAAAAAATAEVAELDDDWKEF
CCCHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6302843; 11677609; 1660187; 8486661; 8831788 [H]