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The map label for this gene is atoS [C]

Identifier: 197117295

GI number: 197117295

Start: 1064579

End: 1066708

Strand: Reverse

Name: atoS [C]

Synonym: Gbem_0905

Alternate gene names: 197117295

Gene position: 1066708-1064579 (Counterclockwise)

Preceding gene: 197117296

Following gene: 197117293

Centisome position: 23.11

GC content: 62.44

Gene sequence:

>2130_bases
ATGGGAAGCGAATCCAAAAAGAGAGCGGCACGGGAGATAGGGAAGATAGTCGGGATCTACGCGCTTTTCGGAAGCGCCTG
GATCTACCTCTCCGGGTATGCCCTCGTCTGGCTGGTAACGGACCCGCACCTGGCGAACCAGATAGAGGTGTACAAGGGGC
TCCTCTTCATCCTAGTCACCTCCGCGCTTTTGTACCAGTTGATCACCCGCTTCGCCAAAAGGCTCGCGGAATCGGTAGAA
AAGCTGGAGGAGAGCGAGGCGCGCTTCCAGGCCATCTACCACAACGTGAACGACGCCCTGCTGATTCACGAGCCGGGCGG
ACGGGTAACCGACGTGAACCGCACCATGTGCAGCATGTTCGGCTACAGCAGGGAAGAAGCGCTGCAACTTGGCGTCGGGC
AGTTAAGCCAGGGGGAGCCACCCTACTCCGAGCAAGAGGCGCGACACCTGCTCACGCTTGCGGCGCAAGGGGTCCCGCAG
ACGGCCCAGTGGCGCAGCAAAAAGAAGAACGGGACCTTGTTCTGGTCCGAGGTCAGCCTGCGCCGGGCCACCATCAACGA
CGAAGAGCGGATCATCGTCATGGTGCGGGACATCGCTGCCCGAAAGGAAGTCGAGGAGGCGCTTAGGCAAAACGAGGAAA
TTCTCAAGCTATTGATGGAGGAGATGCCGGCGGGGGTGGGATGGTCGGACGAAGGGAGGGTAATCCAGTACCTGAACGGC
CTGCTCAGCGAATGGCTGGGCCTTGCCTGTTCCGGGAAGCCAACCCTGGAAGACCTGCTGCAACGCGCCCTGCCCGACCC
TGAGTATCGCGCCCGGGTCCAGCGGCTGTGGGACGCCGGCATCGGCGAAACCCTGAAAAACGGCACCCCCATCCCCCCCA
TCGAAGCGAAGCTGACCTGCAGCGACGGCTCCATCAAGCACGTCATACTCAACACCCGCCTGATCCACCACCGCATACTC
TTCATCTTCACCGACATCACCAAATGGGAAGCGCTGCAAACCGAGATCCTCAAGGCGCAGAAGCTGGAATCGCTGGGGAT
CCTGGCCGGCGGCATAGCCCACGATTTCAACAACATCCTCACCGGCATCCTGGGCAACATCTCCTTTGCCGGTCTGTTGA
CGGCAAGCGATCACCCGGCGCGCAGGCCCCTGGAGCACGCGGAAAAGGCGTCCCAGCGCGCGGCGGAACTGGCGCACCAG
CTCCTTACCTTCTCCCGGGGAGGGGAGCCGCTGAAGAAGGTGGTTTCCGCGGCGCAACTGGTACGGGAATCGCTCGCCCT
GTCGCTGCACGGGTCCAAGGTGCAGACCGAGGTGGAGATCCCCGAGTCCCTGCACGCGATAGAGGCGGACGAAGGGCAGA
TGAGCCAGTCCTTCAACAACGTGATCATCAACGCCTGCCAGGCCATGCCGGATGGGGGGGTATTGAAGGTGAAGGCGGGA
AACGTCTCGCTAGATGCGCAAAACGAGTTGGGGCTGGCAGCGGGGGAGTACATTTGGATCTCGTTCATCGATGAGGGGTG
CGGCATACCGTTCGAGGAACAGAAGATGATCTTCGACCCCTATTTCACCACCAAGGCAGACGGCACCGGGCTGGGGCTGG
CCTCCGTGCACTCCATTGTTTCCAGGCATGCGGGGAAGGTGGAGGTGATCAGCGCGCCCGGGAAGGGCACCACCCTCACC
TTCTACCTCCCCTCGACGGGAGGAGTCATGCCCGAACAGGAGAAGAAGTCTGCAGTGCCCTGTCCCGCGGAGGGCGGCGA
GGGTCCCGTGCTGGTCATGGATGACGAGGAGGCGATCAGGACGCTGGCCGAAGATCTGCTGACCCATCTGGGGCACGCTA
CGGTCACCTGCGGCACAGGGGAAGAGGCGGTCCGGCTCTACAGGGAGGCAAGCGAGGCAGGGCACCCGTTTTTCGCCGCC
ATCATGGATCTGACCGTACCGGCTGGCATGGGGGGGCGGGAAGCCGCCCGGGAGATCCTGGCCTTCGATCCCCAGGCCCG
GCTCATCGTCTCCAGCGGCTATTCCAACGACCCGGTCATGTCGCGGTACGCCGATTACGGGTTCTGTTGCGCCGTGGTGA
AGCCGTACCGTTGGGCGGACCTGCAACAGGCACTGCAAAAAAAGAGCTAG

Upstream 100 bases:

>100_bases
GGGTACCGGGTGACCGAATCGGGGATCGTCGTGGTGTCGAACCCCGACGCGAGGTAAGCCCCCGCCCGCGGGGTAAAAAT
CGCAGGCGACCGGAGCGCTG

Downstream 100 bases:

>100_bases
CCGCGCCTGTCCGACCCCTGGCCGGCCAGCGCCCTACCCCGTGACTGCAATCACCTCTTCGTAAGTGGAGATCCCCTCCA
GCATCTTGCGGATGGCCTGC

Product: PAS domain-containing sensor histidine kinase response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 709; Mature: 708

Protein sequence:

>709_residues
MGSESKKRAAREIGKIVGIYALFGSAWIYLSGYALVWLVTDPHLANQIEVYKGLLFILVTSALLYQLITRFAKRLAESVE
KLEESEARFQAIYHNVNDALLIHEPGGRVTDVNRTMCSMFGYSREEALQLGVGQLSQGEPPYSEQEARHLLTLAAQGVPQ
TAQWRSKKKNGTLFWSEVSLRRATINDEERIIVMVRDIAARKEVEEALRQNEEILKLLMEEMPAGVGWSDEGRVIQYLNG
LLSEWLGLACSGKPTLEDLLQRALPDPEYRARVQRLWDAGIGETLKNGTPIPPIEAKLTCSDGSIKHVILNTRLIHHRIL
FIFTDITKWEALQTEILKAQKLESLGILAGGIAHDFNNILTGILGNISFAGLLTASDHPARRPLEHAEKASQRAAELAHQ
LLTFSRGGEPLKKVVSAAQLVRESLALSLHGSKVQTEVEIPESLHAIEADEGQMSQSFNNVIINACQAMPDGGVLKVKAG
NVSLDAQNELGLAAGEYIWISFIDEGCGIPFEEQKMIFDPYFTTKADGTGLGLASVHSIVSRHAGKVEVISAPGKGTTLT
FYLPSTGGVMPEQEKKSAVPCPAEGGEGPVLVMDDEEAIRTLAEDLLTHLGHATVTCGTGEEAVRLYREASEAGHPFFAA
IMDLTVPAGMGGREAAREILAFDPQARLIVSSGYSNDPVMSRYADYGFCCAVVKPYRWADLQQALQKKS

Sequences:

>Translated_709_residues
MGSESKKRAAREIGKIVGIYALFGSAWIYLSGYALVWLVTDPHLANQIEVYKGLLFILVTSALLYQLITRFAKRLAESVE
KLEESEARFQAIYHNVNDALLIHEPGGRVTDVNRTMCSMFGYSREEALQLGVGQLSQGEPPYSEQEARHLLTLAAQGVPQ
TAQWRSKKKNGTLFWSEVSLRRATINDEERIIVMVRDIAARKEVEEALRQNEEILKLLMEEMPAGVGWSDEGRVIQYLNG
LLSEWLGLACSGKPTLEDLLQRALPDPEYRARVQRLWDAGIGETLKNGTPIPPIEAKLTCSDGSIKHVILNTRLIHHRIL
FIFTDITKWEALQTEILKAQKLESLGILAGGIAHDFNNILTGILGNISFAGLLTASDHPARRPLEHAEKASQRAAELAHQ
LLTFSRGGEPLKKVVSAAQLVRESLALSLHGSKVQTEVEIPESLHAIEADEGQMSQSFNNVIINACQAMPDGGVLKVKAG
NVSLDAQNELGLAAGEYIWISFIDEGCGIPFEEQKMIFDPYFTTKADGTGLGLASVHSIVSRHAGKVEVISAPGKGTTLT
FYLPSTGGVMPEQEKKSAVPCPAEGGEGPVLVMDDEEAIRTLAEDLLTHLGHATVTCGTGEEAVRLYREASEAGHPFFAA
IMDLTVPAGMGGREAAREILAFDPQARLIVSSGYSNDPVMSRYADYGFCCAVVKPYRWADLQQALQKKS
>Mature_708_residues
GSESKKRAAREIGKIVGIYALFGSAWIYLSGYALVWLVTDPHLANQIEVYKGLLFILVTSALLYQLITRFAKRLAESVEK
LEESEARFQAIYHNVNDALLIHEPGGRVTDVNRTMCSMFGYSREEALQLGVGQLSQGEPPYSEQEARHLLTLAAQGVPQT
AQWRSKKKNGTLFWSEVSLRRATINDEERIIVMVRDIAARKEVEEALRQNEEILKLLMEEMPAGVGWSDEGRVIQYLNGL
LSEWLGLACSGKPTLEDLLQRALPDPEYRARVQRLWDAGIGETLKNGTPIPPIEAKLTCSDGSIKHVILNTRLIHHRILF
IFTDITKWEALQTEILKAQKLESLGILAGGIAHDFNNILTGILGNISFAGLLTASDHPARRPLEHAEKASQRAAELAHQL
LTFSRGGEPLKKVVSAAQLVRESLALSLHGSKVQTEVEIPESLHAIEADEGQMSQSFNNVIINACQAMPDGGVLKVKAGN
VSLDAQNELGLAAGEYIWISFIDEGCGIPFEEQKMIFDPYFTTKADGTGLGLASVHSIVSRHAGKVEVISAPGKGTTLTF
YLPSTGGVMPEQEKKSAVPCPAEGGEGPVLVMDDEEAIRTLAEDLLTHLGHATVTCGTGEEAVRLYREASEAGHPFFAAI
MDLTVPAGMGGREAAREILAFDPQARLIVSSGYSNDPVMSRYADYGFCCAVVKPYRWADLQQALQKKS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=292, Percent_Identity=35.2739726027397, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=33.1932773109244, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI48994928, Length=503, Percent_Identity=22.4652087475149, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI145693157, Length=308, Percent_Identity=25, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790300, Length=228, Percent_Identity=30.2631578947368, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77622; Mature: 77490

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSESKKRAAREIGKIVGIYALFGSAWIYLSGYALVWLVTDPHLANQIEVYKGLLFILVT
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEEEEECCCHHHHHHHHHHHHHHHHH
SALLYQLITRFAKRLAESVEKLEESEARFQAIYHNVNDALLIHEPGGRVTDVNRTMCSMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHH
GYSREEALQLGVGQLSQGEPPYSEQEARHLLTLAAQGVPQTAQWRSKKKNGTLFWSEVSL
CCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEHHH
RRATINDEERIIVMVRDIAARKEVEEALRQNEEILKLLMEEMPAGVGWSDEGRVIQYLNG
EEECCCCCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LLSEWLGLACSGKPTLEDLLQRALPDPEYRARVQRLWDAGIGETLKNGTPIPPIEAKLTC
HHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEE
SDGSIKHVILNTRLIHHRILFIFTDITKWEALQTEILKAQKLESLGILAGGIAHDFNNIL
CCCCEEEEEEHHHHHHHEEEHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGILGNISFAGLLTASDHPARRPLEHAEKASQRAAELAHQLLTFSRGGEPLKKVVSAAQL
HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VRESLALSLHGSKVQTEVEIPESLHAIEADEGQMSQSFNNVIINACQAMPDGGVLKVKAG
HHHHHHHEECCCEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
NVSLDAQNELGLAAGEYIWISFIDEGCGIPFEEQKMIFDPYFTTKADGTGLGLASVHSIV
CEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHH
SRHAGKVEVISAPGKGTTLTFYLPSTGGVMPEQEKKSAVPCPAEGGEGPVLVMDDEEAIR
HHCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCEEEECCHHHHH
TLAEDLLTHLGHATVTCGTGEEAVRLYREASEAGHPFFAAIMDLTVPAGMGGREAAREIL
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
AFDPQARLIVSSGYSNDPVMSRYADYGFCCAVVKPYRWADLQQALQKKS
HCCCCCEEEEECCCCCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GSESKKRAAREIGKIVGIYALFGSAWIYLSGYALVWLVTDPHLANQIEVYKGLLFILVT
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEEEEECCCHHHHHHHHHHHHHHHHH
SALLYQLITRFAKRLAESVEKLEESEARFQAIYHNVNDALLIHEPGGRVTDVNRTMCSMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHH
GYSREEALQLGVGQLSQGEPPYSEQEARHLLTLAAQGVPQTAQWRSKKKNGTLFWSEVSL
CCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEHHH
RRATINDEERIIVMVRDIAARKEVEEALRQNEEILKLLMEEMPAGVGWSDEGRVIQYLNG
EEECCCCCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
LLSEWLGLACSGKPTLEDLLQRALPDPEYRARVQRLWDAGIGETLKNGTPIPPIEAKLTC
HHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEE
SDGSIKHVILNTRLIHHRILFIFTDITKWEALQTEILKAQKLESLGILAGGIAHDFNNIL
CCCCEEEEEEHHHHHHHEEEHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGILGNISFAGLLTASDHPARRPLEHAEKASQRAAELAHQLLTFSRGGEPLKKVVSAAQL
HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VRESLALSLHGSKVQTEVEIPESLHAIEADEGQMSQSFNNVIINACQAMPDGGVLKVKAG
HHHHHHHEECCCEEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECC
NVSLDAQNELGLAAGEYIWISFIDEGCGIPFEEQKMIFDPYFTTKADGTGLGLASVHSIV
CEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHH
SRHAGKVEVISAPGKGTTLTFYLPSTGGVMPEQEKKSAVPCPAEGGEGPVLVMDDEEAIR
HHCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCEEEECCHHHHH
TLAEDLLTHLGHATVTCGTGEEAVRLYREASEAGHPFFAAIMDLTVPAGMGGREAAREIL
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
AFDPQARLIVSSGYSNDPVMSRYADYGFCCAVVKPYRWADLQQALQKKS
HCCCCCEEEEECCCCCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA