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The map label for this gene is ntrY [H]

Identifier: 197117290

GI number: 197117290

Start: 1057075

End: 1059345

Strand: Reverse

Name: ntrY [H]

Synonym: Gbem_0900

Alternate gene names: 197117290

Gene position: 1059345-1057075 (Counterclockwise)

Preceding gene: 197117291

Following gene: 197117289

Centisome position: 22.95

GC content: 61.25

Gene sequence:

>2271_bases
ATGCCGATTTCAGCCGAAAAAGGGGGAACGCCCCCGCAATACCAGGGGCCGGAACTTTCCGCCGGTGAAGTAAGGAAAAG
AAAGCGCGAGGCCATAATCGTCTGCCTCTCGCTGTTAACCATCTGCCTCCTCACCTACCTGGAGATCCACCTCTCCCGCC
TAAGCGAGCAGGTGCCGATGGGCAGCAACATCGCCATCTTCGGCATGGTAAACCTGATCATCCTCCTCATCATCCTGCTG
GTCTACCTGGTCTTCAGAAACATAGCCAAACTGGTCCTGGAGCGGCGCAAGAACACGCCGGGGGCGAAGCTGCGCACGAA
GCTGGTGCTTGCCTTCGTCACCCTCTCGCTGGTCCCGACCATGCTGCTGTTCTTCGTCTCCGCCGGCTTCATCAAGAACA
GCATCTCGAACTGGTTCAACAAGCAGGTGGAGACCTCGCTCAACGAGTCGATGGAGGTGGCCCAGGTCTATTACCAGACC
TCCGCGGCCAACGCCCTCTACTACGGCGAGCAGATCAGCACCGCCATCAAGGAACGTAAGCTTCTGAACGAGGAGAACCT
CCCCAAGCTGAAGGCCCTGGTGCGCCAGAAACAGACCGAATATAACCTGGGGGTGGTCGAGGTCTTCTCGGCGCAGCGCG
AGGAGCTGTTCCGGGCGGGCAATGCCAAGCTGCCGCTGGGTGAATTCACCAACCCCTCGTCAGAGGATATCCAACGCGTC
CTCTCCGGGGCCAGGCTTACCCGCGTCAACGCCATCGGCAAGGCCGACCTGATCCGCGGCATAGTCCCCATCCACAGCAA
CTTCAACGAGAACGACGTGGTCGGGGTGGTGGTGGTCAACTACTACGTTCCCTACTCGCTGGTGTCCAAGATGCGGGAGA
TCTCCTCCTCCTACCAGGAGTTCCGCCAGCTGAAGATCCTGAAAAACCCGATCAGGACCGGATACATACTCACCCTGTTC
CTGATCACCATGGTGATCCTATTCCTGGCCGTGTGGTTCGGGATGTACCTCGCCCGAAGCCTCACCATCCCGATTCAGGA
ACTGGCGGAGGCGACCCGGCAGGTGGCCGAGGGGAACCTGGACGTACACCTGGGCCAAAGCGGGGGGGACGAGATAGGGA
TGCTGATCTCCTCCTTCAACCGGATGACCGAGGACCTCCGGGCGAACCAGCTCGCGCTGCAGCACACCAACGAGGAACTG
CAAAAGAGCAACCTCGAGTTGGAGCAGCGCCGCCGCTACATGGAGGCGGTGCTCGCCAACGTCACCGCCGGCATCATCTC
GGTGGACAAGAACGGCCTGCTCACCACGGTGAACAAATCGGCCGAAAAGCTGCTCCTCATCGACACGGACAGGGTCACCG
GGCAGAACTTCCGCGAGGTGCTGCGCCCGGAGCACCTGGACATCGTCAAGGGGCTCCTGCGGGACATGGTGCTTGCCAAG
CACGACTCCATCGTGCGGCAGGTGGTGATCCCGATGCGCGACGCGGAGCTCACCCTGCTCACCAACCTCACCGTCCTGAA
GGACGAAAATGACGCCTTCATGGGAATGGTGGTGGTGCTGGACGACATGACCTCGCTGATCAAGGCGCAGCGCATGGCCG
CCTGGCGCGAAGTGGCCCGAAGGATCGCCCACGAGATCAAGAACCCGCTCACCCCGATCCAGCTCTCCGCCCAGCGGCTG
AGGAAGCGCTACCTCACCCGGTTCGAGGGGGAGGAGGAGGTGTTCGACCAGTGCACCGCCATGATCATCAAGTCCGTGGA
CGAGCTGAAGGGGCTGGTGAACGAGTTCTCCAACTTCGCCCGGATGCCGGCCGCGGTGCTGAAGCCAAACGACCTGAACG
GGATACTCAAGGAGGCGCTCACCCTCTACGACGAGGCGCACCGGCACATACGCTTCGTGCTGAACGCCGACGAGGCAATC
CCCCCTATCCTTTTGGACCGCGACCAGATCAAGCGGGTAGTGATCAACCTCTTGGACAACGCCGTCGCCGCCATAGAGGG
GGAGGGGGAGGGAGTGGTCGAGCTCAGCACCAGCTACGACAGCCAGTTGAAGATGGTCACTTTCACCGTTTCCGACACCG
GTCACGGCATATCCGCCGAAGACCGCCCGCGGCTCTTCGAGCCGTACTTCTCCCGCAAGAAGAGCGGCACGGGGCTCGGG
CTTGCCATCGTCAACACCATCATCACCGACCACCACGGCTTCATCAGAGCCAAGGAAAACTACCCCAAGGGGAGCAGGTT
CGTCATCGAGCTCCCCGCTGACGCGGCATAA

Upstream 100 bases:

>100_bases
TAAGCGAATCGGAGCAGCCACCAGACAGGGGCTGCTCTTTTCGTTTACAGCTCCTTTTGCACTACTTGAAATCCCGCAAC
CTTTCGTATAGAGTGCCCAA

Downstream 100 bases:

>100_bases
CAGAAGCAGATAGAGATAAAGATAAAGATTGAGAAAACGAATAAAAAGCAGATTGACTTAAGATTGAGATTTAAGAAAGT
TTTTGACTCTCCTTTATCTT

Product: nitrogen regulation sensor histidine kinase NtrY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 756; Mature: 755

Protein sequence:

>756_residues
MPISAEKGGTPPQYQGPELSAGEVRKRKREAIIVCLSLLTICLLTYLEIHLSRLSEQVPMGSNIAIFGMVNLIILLIILL
VYLVFRNIAKLVLERRKNTPGAKLRTKLVLAFVTLSLVPTMLLFFVSAGFIKNSISNWFNKQVETSLNESMEVAQVYYQT
SAANALYYGEQISTAIKERKLLNEENLPKLKALVRQKQTEYNLGVVEVFSAQREELFRAGNAKLPLGEFTNPSSEDIQRV
LSGARLTRVNAIGKADLIRGIVPIHSNFNENDVVGVVVVNYYVPYSLVSKMREISSSYQEFRQLKILKNPIRTGYILTLF
LITMVILFLAVWFGMYLARSLTIPIQELAEATRQVAEGNLDVHLGQSGGDEIGMLISSFNRMTEDLRANQLALQHTNEEL
QKSNLELEQRRRYMEAVLANVTAGIISVDKNGLLTTVNKSAEKLLLIDTDRVTGQNFREVLRPEHLDIVKGLLRDMVLAK
HDSIVRQVVIPMRDAELTLLTNLTVLKDENDAFMGMVVVLDDMTSLIKAQRMAAWREVARRIAHEIKNPLTPIQLSAQRL
RKRYLTRFEGEEEVFDQCTAMIIKSVDELKGLVNEFSNFARMPAAVLKPNDLNGILKEALTLYDEAHRHIRFVLNADEAI
PPILLDRDQIKRVVINLLDNAVAAIEGEGEGVVELSTSYDSQLKMVTFTVSDTGHGISAEDRPRLFEPYFSRKKSGTGLG
LAIVNTIITDHHGFIRAKENYPKGSRFVIELPADAA

Sequences:

>Translated_756_residues
MPISAEKGGTPPQYQGPELSAGEVRKRKREAIIVCLSLLTICLLTYLEIHLSRLSEQVPMGSNIAIFGMVNLIILLIILL
VYLVFRNIAKLVLERRKNTPGAKLRTKLVLAFVTLSLVPTMLLFFVSAGFIKNSISNWFNKQVETSLNESMEVAQVYYQT
SAANALYYGEQISTAIKERKLLNEENLPKLKALVRQKQTEYNLGVVEVFSAQREELFRAGNAKLPLGEFTNPSSEDIQRV
LSGARLTRVNAIGKADLIRGIVPIHSNFNENDVVGVVVVNYYVPYSLVSKMREISSSYQEFRQLKILKNPIRTGYILTLF
LITMVILFLAVWFGMYLARSLTIPIQELAEATRQVAEGNLDVHLGQSGGDEIGMLISSFNRMTEDLRANQLALQHTNEEL
QKSNLELEQRRRYMEAVLANVTAGIISVDKNGLLTTVNKSAEKLLLIDTDRVTGQNFREVLRPEHLDIVKGLLRDMVLAK
HDSIVRQVVIPMRDAELTLLTNLTVLKDENDAFMGMVVVLDDMTSLIKAQRMAAWREVARRIAHEIKNPLTPIQLSAQRL
RKRYLTRFEGEEEVFDQCTAMIIKSVDELKGLVNEFSNFARMPAAVLKPNDLNGILKEALTLYDEAHRHIRFVLNADEAI
PPILLDRDQIKRVVINLLDNAVAAIEGEGEGVVELSTSYDSQLKMVTFTVSDTGHGISAEDRPRLFEPYFSRKKSGTGLG
LAIVNTIITDHHGFIRAKENYPKGSRFVIELPADAA
>Mature_755_residues
PISAEKGGTPPQYQGPELSAGEVRKRKREAIIVCLSLLTICLLTYLEIHLSRLSEQVPMGSNIAIFGMVNLIILLIILLV
YLVFRNIAKLVLERRKNTPGAKLRTKLVLAFVTLSLVPTMLLFFVSAGFIKNSISNWFNKQVETSLNESMEVAQVYYQTS
AANALYYGEQISTAIKERKLLNEENLPKLKALVRQKQTEYNLGVVEVFSAQREELFRAGNAKLPLGEFTNPSSEDIQRVL
SGARLTRVNAIGKADLIRGIVPIHSNFNENDVVGVVVVNYYVPYSLVSKMREISSSYQEFRQLKILKNPIRTGYILTLFL
ITMVILFLAVWFGMYLARSLTIPIQELAEATRQVAEGNLDVHLGQSGGDEIGMLISSFNRMTEDLRANQLALQHTNEELQ
KSNLELEQRRRYMEAVLANVTAGIISVDKNGLLTTVNKSAEKLLLIDTDRVTGQNFREVLRPEHLDIVKGLLRDMVLAKH
DSIVRQVVIPMRDAELTLLTNLTVLKDENDAFMGMVVVLDDMTSLIKAQRMAAWREVARRIAHEIKNPLTPIQLSAQRLR
KRYLTRFEGEEEVFDQCTAMIIKSVDELKGLVNEFSNFARMPAAVLKPNDLNGILKEALTLYDEAHRHIRFVLNADEAIP
PILLDRDQIKRVVINLLDNAVAAIEGEGEGVVELSTSYDSQLKMVTFTVSDTGHGISAEDRPRLFEPYFSRKKSGTGLGL
AIVNTIITDHHGFIRAKENYPKGSRFVIELPADAA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=355, Percent_Identity=26.7605633802817, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=32.3144104803493, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1790300, Length=236, Percent_Identity=30.9322033898305, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=255, Percent_Identity=28.6274509803922, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1789808, Length=198, Percent_Identity=28.7878787878788, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=375, Percent_Identity=24.2666666666667, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=265, Percent_Identity=26.7924528301887, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788393, Length=241, Percent_Identity=25.7261410788382, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84891; Mature: 84760

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISAEKGGTPPQYQGPELSAGEVRKRKREAIIVCLSLLTICLLTYLEIHLSRLSEQVPM
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GSNIAIFGMVNLIILLIILLVYLVFRNIAKLVLERRKNTPGAKLRTKLVLAFVTLSLVPT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
MLLFFVSAGFIKNSISNWFNKQVETSLNESMEVAQVYYQTSAANALYYGEQISTAIKERK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LLNEENLPKLKALVRQKQTEYNLGVVEVFSAQREELFRAGNAKLPLGEFTNPSSEDIQRV
HCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
LSGARLTRVNAIGKADLIRGIVPIHSNFNENDVVGVVVVNYYVPYSLVSKMREISSSYQE
HCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHH
FRQLKILKNPIRTGYILTLFLITMVILFLAVWFGMYLARSLTIPIQELAEATRQVAEGNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
DVHLGQSGGDEIGMLISSFNRMTEDLRANQLALQHTNEELQKSNLELEQRRRYMEAVLAN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VTAGIISVDKNGLLTTVNKSAEKLLLIDTDRVTGQNFREVLRPEHLDIVKGLLRDMVLAK
HHHHHEEECCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
HDSIVRQVVIPMRDAELTLLTNLTVLKDENDAFMGMVVVLDDMTSLIKAQRMAAWREVAR
HHHHHHHHHHCCCCCCEEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAHEIKNPLTPIQLSAQRLRKRYLTRFEGEEEVFDQCTAMIIKSVDELKGLVNEFSNFA
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMPAAVLKPNDLNGILKEALTLYDEAHRHIRFVLNADEAIPPILLDRDQIKRVVINLLDN
HCCHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
AVAAIEGEGEGVVELSTSYDSQLKMVTFTVSDTGHGISAEDRPRLFEPYFSRKKSGTGLG
HHHEEECCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCHH
LAIVNTIITDHHGFIRAKENYPKGSRFVIELPADAA
HHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
PISAEKGGTPPQYQGPELSAGEVRKRKREAIIVCLSLLTICLLTYLEIHLSRLSEQVPM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GSNIAIFGMVNLIILLIILLVYLVFRNIAKLVLERRKNTPGAKLRTKLVLAFVTLSLVPT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
MLLFFVSAGFIKNSISNWFNKQVETSLNESMEVAQVYYQTSAANALYYGEQISTAIKERK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LLNEENLPKLKALVRQKQTEYNLGVVEVFSAQREELFRAGNAKLPLGEFTNPSSEDIQRV
HCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
LSGARLTRVNAIGKADLIRGIVPIHSNFNENDVVGVVVVNYYVPYSLVSKMREISSSYQE
HCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHH
FRQLKILKNPIRTGYILTLFLITMVILFLAVWFGMYLARSLTIPIQELAEATRQVAEGNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
DVHLGQSGGDEIGMLISSFNRMTEDLRANQLALQHTNEELQKSNLELEQRRRYMEAVLAN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VTAGIISVDKNGLLTTVNKSAEKLLLIDTDRVTGQNFREVLRPEHLDIVKGLLRDMVLAK
HHHHHEEECCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
HDSIVRQVVIPMRDAELTLLTNLTVLKDENDAFMGMVVVLDDMTSLIKAQRMAAWREVAR
HHHHHHHHHHCCCCCCEEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAHEIKNPLTPIQLSAQRLRKRYLTRFEGEEEVFDQCTAMIIKSVDELKGLVNEFSNFA
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMPAAVLKPNDLNGILKEALTLYDEAHRHIRFVLNADEAIPPILLDRDQIKRVVINLLDN
HCCHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
AVAAIEGEGEGVVELSTSYDSQLKMVTFTVSDTGHGISAEDRPRLFEPYFSRKKSGTGLG
HHHEEECCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCHH
LAIVNTIITDHHGFIRAKENYPKGSRFVIELPADAA
HHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]