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The map label for this gene is cyaA [H]

Identifier: 197116696

GI number: 197116696

Start: 362205

End: 364223

Strand: Direct

Name: cyaA [H]

Synonym: Gbem_0296

Alternate gene names: 197116696

Gene position: 362205-364223 (Clockwise)

Preceding gene: 197116689

Following gene: 308535155

Centisome position: 7.85

GC content: 64.78

Gene sequence:

>2019_bases
ATGCAAAACCCGTTCAACGTTCGGCGTTCAAGGTTCGCTGCCCCATCGCGTCGTCATCTCAGCTCAGCCACAATCCGCTT
CCTTATCGGCTGCGCCGTGACCGCGCTCTTTTGCCTGTTGCTGGTTGAGAATCCGCTCCCGCTGGAGATCACCGAGGCGA
AGCTCTACGACCTCCGTTTCCATCTGCGCGGCCCGGTGAAGGCGCCGGACCAGGTGGTGATAGCGGTCATCGACGAGAAA
AGCCTGGCGAGGCTGGGGCGCTGGCCCTGGAGCCGCGAGGTGATGGCGGGGCTGGTGGACAAGCTGGCCCGGGCCGAGGC
GGCGGTGATCGCCTTCGACGTGATCTTTCCCGAAAGCGACGAGGACGACCGGATTCTCTCCCGCGCCATAGCCGACGCCG
GCAACGTCGTTCTTCCCATCGTCTTCGACTTCGAGACCGCCTCCAAACGGCGCGCCAACCCGGACCTGGAGCCGTCGGCG
CTTACCGCGATCCTGGAACCTGAGCTGTACCGGAACTTCCCCCCCATAACCTCGGGCGGGGTACCGATCATGCCGGTGAA
GCCGCTTAGGGATAGCGCCATGTCGCTGGCGCACATCAGCATGCTGCCCGATTACTTCGACGGGACGCTCCGCTGGGAGG
CCCTTGTGGTCGCCTACGACGGCCTCCTCTACCCCTCCCTGGGACTCAAGAGCGCCGCCTTCTTCAAGGGGGTCTCCGCA
GACAAGCTGCAGGTGCACGCCGCCAGTTCCATCGCGGTCGGCAATACGGTGATCCCCACCGACCGCTGGGGGCGCATGCC
GATCAACTACTACGGGCCGGGGCGGACGCTGCGCCACATCTCCATCGCGGACATCGTCGACGGCAAGGTGGGCGCGAAAG
AGCTCGGCAACCGGATCGTCTTCATCGGCGCCTCCGCCGTCGGCATGCTGGATCTAAGGGTCACCCCATTCACGGCGGTC
ATGCCCGGGGTGGAGAAGCAGGCGACCATCGCCGCTTCCATCCTGGAGAACCGGTTCCTGGTGAAAGCGACAAAGGGGGA
GGACCTTCTCTTCCTGCTCCTGACGGGGTTGGCCATGGCGCTGGTCTTGAGCCGCTTGCGGCTTTTGTGGGGGGCGGTGG
CGGTAGCGGCCGGCGGTGCGGCCATCGCTGCCGCCGGGGTCGTCCTCTTCAGCCGCTTCGGCGTGTGGGTGAACCTCGCC
TGCCCGATGGGGAACGTCCTTTGCCTCTTCATGTCGGTGACCGGCTGGAACTACACGGTCGAGGAGCGCCGCGCCCGCAG
GATACGCGCCATGTTCTCAAGCTACGTCACCACGACCATCGTCAACGAGCTGATCGAGAACCCGGCCCTGGCGAGGCTCG
GCGGCGAGAAGCGCGAGATAAGCATCCTCTTCTCCGACGTGAGGGGGTTCACCACCTTTTCCGAGCAGCACGCGCCGGAG
GAAGTGGTCGCCCTCCTGAACGAGTACCTGGGGGAGATGACCGACGTCATCCTCAAGTGGGGGGGGACCCTCGATAAGTT
CATCGGCGACGCCATCATGGTCTTTTGGAACGCGCCGCTTCCCTGCGCCGACCACGCCGAGCGAGCGGTGCGCTGCGCGC
TGGAGTTACAGGCGCGGCTTGCGGAACTCCACGGGAAGTGGGACCGGGAGGGGAAACCGAAGCTTAGCTGCGGCATCGGC
ATCAACACCGGCGAGGTCATCGTCGGGAACATCGGCGCCGAGGGGAAGAAGATGGACTACACCGTCATTGGCGACGAGGT
GAACCTGGCGAGCCGGGTCGAGTCGCTGACCCGCCGCTTCGATGCGGGGATCCTCATCACCGAGAAGACGGTGGAGAAGC
TGCGAGGCGCCATCGAGGCGGGGACGCTCTCCGGCATCGAGTTGAGCGGCATCAGCCGGGTGATCGTCAAAGGGAAGGAG
CAGCCGGTGACGCTCTACACCGCAGTTACCAATGGAACCGCTCCCGCCGTCATCATCGAGTGCGAGGAGATGGAACCTGT
GAGACTGACGGAAAAATAA

Upstream 100 bases:

>100_bases
ATGTCGAAACGTTACAGGTATAGCTCATCGGCAGATAGATTCATGAACTGAAGGAATTGCTCGCAGACAAGAGGCGACTC
CTTCCCGGGGCGCTCCCCTT

Downstream 100 bases:

>100_bases
AAGCCCAACCCCAAAACCATTAGCAAGGAGAAAATCTGAGGACTTCTGAGAACTGCCTTGACGGAGAACTGTCTTAACCT
TCCGTTTCGGTTCTCTCAGA

Product: CHASE2 sensor adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MQNPFNVRRSRFAAPSRRHLSSATIRFLIGCAVTALFCLLLVENPLPLEITEAKLYDLRFHLRGPVKAPDQVVIAVIDEK
SLARLGRWPWSREVMAGLVDKLARAEAAVIAFDVIFPESDEDDRILSRAIADAGNVVLPIVFDFETASKRRANPDLEPSA
LTAILEPELYRNFPPITSGGVPIMPVKPLRDSAMSLAHISMLPDYFDGTLRWEALVVAYDGLLYPSLGLKSAAFFKGVSA
DKLQVHAASSIAVGNTVIPTDRWGRMPINYYGPGRTLRHISIADIVDGKVGAKELGNRIVFIGASAVGMLDLRVTPFTAV
MPGVEKQATIAASILENRFLVKATKGEDLLFLLLTGLAMALVLSRLRLLWGAVAVAAGGAAIAAAGVVLFSRFGVWVNLA
CPMGNVLCLFMSVTGWNYTVEERRARRIRAMFSSYVTTTIVNELIENPALARLGGEKREISILFSDVRGFTTFSEQHAPE
EVVALLNEYLGEMTDVILKWGGTLDKFIGDAIMVFWNAPLPCADHAERAVRCALELQARLAELHGKWDREGKPKLSCGIG
INTGEVIVGNIGAEGKKMDYTVIGDEVNLASRVESLTRRFDAGILITEKTVEKLRGAIEAGTLSGIELSGISRVIVKGKE
QPVTLYTAVTNGTAPAVIIECEEMEPVRLTEK

Sequences:

>Translated_672_residues
MQNPFNVRRSRFAAPSRRHLSSATIRFLIGCAVTALFCLLLVENPLPLEITEAKLYDLRFHLRGPVKAPDQVVIAVIDEK
SLARLGRWPWSREVMAGLVDKLARAEAAVIAFDVIFPESDEDDRILSRAIADAGNVVLPIVFDFETASKRRANPDLEPSA
LTAILEPELYRNFPPITSGGVPIMPVKPLRDSAMSLAHISMLPDYFDGTLRWEALVVAYDGLLYPSLGLKSAAFFKGVSA
DKLQVHAASSIAVGNTVIPTDRWGRMPINYYGPGRTLRHISIADIVDGKVGAKELGNRIVFIGASAVGMLDLRVTPFTAV
MPGVEKQATIAASILENRFLVKATKGEDLLFLLLTGLAMALVLSRLRLLWGAVAVAAGGAAIAAAGVVLFSRFGVWVNLA
CPMGNVLCLFMSVTGWNYTVEERRARRIRAMFSSYVTTTIVNELIENPALARLGGEKREISILFSDVRGFTTFSEQHAPE
EVVALLNEYLGEMTDVILKWGGTLDKFIGDAIMVFWNAPLPCADHAERAVRCALELQARLAELHGKWDREGKPKLSCGIG
INTGEVIVGNIGAEGKKMDYTVIGDEVNLASRVESLTRRFDAGILITEKTVEKLRGAIEAGTLSGIELSGISRVIVKGKE
QPVTLYTAVTNGTAPAVIIECEEMEPVRLTEK
>Mature_672_residues
MQNPFNVRRSRFAAPSRRHLSSATIRFLIGCAVTALFCLLLVENPLPLEITEAKLYDLRFHLRGPVKAPDQVVIAVIDEK
SLARLGRWPWSREVMAGLVDKLARAEAAVIAFDVIFPESDEDDRILSRAIADAGNVVLPIVFDFETASKRRANPDLEPSA
LTAILEPELYRNFPPITSGGVPIMPVKPLRDSAMSLAHISMLPDYFDGTLRWEALVVAYDGLLYPSLGLKSAAFFKGVSA
DKLQVHAASSIAVGNTVIPTDRWGRMPINYYGPGRTLRHISIADIVDGKVGAKELGNRIVFIGASAVGMLDLRVTPFTAV
MPGVEKQATIAASILENRFLVKATKGEDLLFLLLTGLAMALVLSRLRLLWGAVAVAAGGAAIAAAGVVLFSRFGVWVNLA
CPMGNVLCLFMSVTGWNYTVEERRARRIRAMFSSYVTTTIVNELIENPALARLGGEKREISILFSDVRGFTTFSEQHAPE
EVVALLNEYLGEMTDVILKWGGTLDKFIGDAIMVFWNAPLPCADHAERAVRCALELQARLAELHGKWDREGKPKLSCGIG
INTGEVIVGNIGAEGKKMDYTVIGDEVNLASRVESLTRRFDAGILITEKTVEKLRGAIEAGTLSGIELSGISRVIVKGKE
QPVTLYTAVTNGTAPAVIIECEEMEPVRLTEK

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17551720, Length=187, Percent_Identity=30.4812834224599, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71989822, Length=194, Percent_Identity=31.9587628865979, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71989805, Length=177, Percent_Identity=30.5084745762712, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508769, Length=143, Percent_Identity=34.2657342657343, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193206632, Length=138, Percent_Identity=35.5072463768116, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17534659, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI161078020, Length=275, Percent_Identity=28, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24642014, Length=215, Percent_Identity=28.8372093023256, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62484298, Length=138, Percent_Identity=34.0579710144928, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI62484477, Length=138, Percent_Identity=34.0579710144928, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116008008, Length=138, Percent_Identity=34.0579710144928, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 73194; Mature: 73194

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNPFNVRRSRFAAPSRRHLSSATIRFLIGCAVTALFCLLLVENPLPLEITEAKLYDLRF
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEEE
HLRGPVKAPDQVVIAVIDEKSLARLGRWPWSREVMAGLVDKLARAEAAVIAFDVIFPESD
EECCCCCCCCCEEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEEEEEEEECCCC
EDDRILSRAIADAGNVVLPIVFDFETASKRRANPDLEPSALTAILEPELYRNFPPITSGG
CHHHHHHHHHHCCCCEEEEEEEECCCCHHCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCC
VPIMPVKPLRDSAMSLAHISMLPDYFDGTLRWEALVVAYDGLLYPSLGLKSAAFFKGVSA
CCEEECCCCHHHHHHHHHHHHCHHHCCCCEEEEEEEEEECCEECCCCCCCHHHHHCCCCC
DKLQVHAASSIAVGNTVIPTDRWGRMPINYYGPGRTLRHISIADIVDGKVGAKELGNRIV
CCEEEEECCEEEECCEECCCCCCCCCCEEEECCCCEEEEEEHHHHHCCCCCHHHHCCEEE
FIGASAVGMLDLRVTPFTAVMPGVEKQATIAASILENRFLVKATKGEDLLFLLLTGLAMA
EEECCCEEEEEEEECCHHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHH
LVLSRLRLLWGAVAVAAGGAAIAAAGVVLFSRFGVWVNLACPMGNVLCLFMSVTGWNYTV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCHHHEEHEEECCCCCEEH
EERRARRIRAMFSSYVTTTIVNELIENPALARLGGEKREISILFSDVRGFTTFSEQHAPE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEEEEHHCCCCCCHHCCCHH
EVVALLNEYLGEMTDVILKWGGTLDKFIGDAIMVFWNAPLPCADHAERAVRCALELQARL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AELHGKWDREGKPKLSCGIGINTGEVIVGNIGAEGKKMDYTVIGDEVNLASRVESLTRRF
HHHCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
DAGILITEKTVEKLRGAIEAGTLSGIELSGISRVIVKGKEQPVTLYTAVTNGTAPAVIIE
CCCEEEEHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCCCEEEEEEEECCCCCEEEEE
CEEMEPVRLTEK
ECCCCCEECCCC
>Mature Secondary Structure
MQNPFNVRRSRFAAPSRRHLSSATIRFLIGCAVTALFCLLLVENPLPLEITEAKLYDLRF
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEEE
HLRGPVKAPDQVVIAVIDEKSLARLGRWPWSREVMAGLVDKLARAEAAVIAFDVIFPESD
EECCCCCCCCCEEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHCEEEEEEEEEECCCC
EDDRILSRAIADAGNVVLPIVFDFETASKRRANPDLEPSALTAILEPELYRNFPPITSGG
CHHHHHHHHHHCCCCEEEEEEEECCCCHHCCCCCCCCHHHHHHHCCHHHHHCCCCCCCCC
VPIMPVKPLRDSAMSLAHISMLPDYFDGTLRWEALVVAYDGLLYPSLGLKSAAFFKGVSA
CCEEECCCCHHHHHHHHHHHHCHHHCCCCEEEEEEEEEECCEECCCCCCCHHHHHCCCCC
DKLQVHAASSIAVGNTVIPTDRWGRMPINYYGPGRTLRHISIADIVDGKVGAKELGNRIV
CCEEEEECCEEEECCEECCCCCCCCCCEEEECCCCEEEEEEHHHHHCCCCCHHHHCCEEE
FIGASAVGMLDLRVTPFTAVMPGVEKQATIAASILENRFLVKATKGEDLLFLLLTGLAMA
EEECCCEEEEEEEECCHHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHH
LVLSRLRLLWGAVAVAAGGAAIAAAGVVLFSRFGVWVNLACPMGNVLCLFMSVTGWNYTV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCHHHEEHEEECCCCCEEH
EERRARRIRAMFSSYVTTTIVNELIENPALARLGGEKREISILFSDVRGFTTFSEQHAPE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEEEEHHCCCCCCHHCCCHH
EVVALLNEYLGEMTDVILKWGGTLDKFIGDAIMVFWNAPLPCADHAERAVRCALELQARL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AELHGKWDREGKPKLSCGIGINTGEVIVGNIGAEGKKMDYTVIGDEVNLASRVESLTRRF
HHHCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
DAGILITEKTVEKLRGAIEAGTLSGIELSGISRVIVKGKEQPVTLYTAVTNGTAPAVIIE
CCCEEEEHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCCCEEEEEEEECCCCCEEEEE
CEEMEPVRLTEK
ECCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]