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The map label for this gene is pepN [H]

Identifier: 197116668

GI number: 197116668

Start: 316609

End: 319251

Strand: Reverse

Name: pepN [H]

Synonym: Gbem_0268

Alternate gene names: 197116668

Gene position: 319251-316609 (Counterclockwise)

Preceding gene: 197116672

Following gene: 197116662

Centisome position: 6.92

GC content: 64.7

Gene sequence:

>2643_bases
ATGCATACCTGCCAGCACCAGACCGTTTACCAGAAAGATTATTCCGCGCCTGACTACCTCGTTGAGACAGTTGAATTGTC
CTTCGACCTGGACCCAGAACTGACCTGGGTTGCGTCCCGGCTCAAGATCCGCTCCAACTACGACCGGGCGCAAGGCTTGC
GGCCGCTGGTTTTGGACGGAGAGGAGCTGACCCTGGTGTCGCTCAAGCTGGACGGGGTCGAACTGGAGCCGGCGCGATAT
ACGGCAGGGGACGGCGCGCTCACCGTGACCGATCCGCCGGAGAGCTTCCTTTTGGAGGTGACCACGCAGATAAGCCCCAA
GGCGAACAGCGCGCTCTCCGGGCTCTATGCCTCCGGCCCCATGCTCTGCACCCAGTGCGAGGCCGAGGGGTTCCGCCGCA
TCACCTACTTCACCGACCGCCCCGACGTCATGGCGGTCTACACCGTCATCTTGAAAGCGGACAAGGGGTCCTGCCCGGTG
CTCTTGGCCAACGGCAACCTGGTGGAAAAGGGGGATCTCCCGGACGGGCGGCATTTCGCCACCTGGCACGACCCGTTTAA
AAAGCCGAGCTACCTCTTCGCCGTGGTGGCGGGGGACCTGGTCCACATCTCGGACCGCTTCACCACCATGAGCGGCCGGC
AGGTCAACCTGGAGATTTACGTCGAAGAGAAGAACCAGGGGAAGTGCGACCACGCGCTCAGGTCGCTCATTGAGGCGATG
CGCTGGGACGAGGAGCAGTTCGGCCGCGAGTACGATCTGGACACCTACATGGTCGTCGCCGTGGACGACTTCAACATGGG
AGCGATGGAGAACAAGGGGTTGAACGTCTTCAACTCGCGCTATGTCCTCGCCAGCCCCGAGACCGCTACCGATGACGACT
ACCAGGCCATCGAAGAGGTGATCGGGCACGAATACTTCCACAACTGGACCGGCAACCGGATTACCTGCCGCGACTGGTTC
CAGCTCTCCTTAAAGGAAGGGCTCACCATCTTCCGGGACCAGGAATTCTCCGCCGACATGCAGTCGCGCCCGGTGAAGAG
GATCGCCGACGTGAGGCTATTGCGCTCCTCCCAGTTCCCCGAGGATGCGAGTCCCCTGGCCCACCCGGTCCGCCCCGACT
CCTACGTGGAGATCAACAACTTCTACAGCATGACGGTCTACCACAAGGGTGGCGAGGTGATCAGGATGCTGCAGACCCTC
CTGGGGCGGGAGGCCTTCCGCGCGGGAATGGACCTGTACTTCGAACGGCACGACGGCCAGGCGGTCCGGGTAGACGAATT
CGTCCAGGCCATGGCGGACGCGGGAAAGCGCGACCTCTCCCAGTTCATGCGCTGGTACAACCAGTCCGGCACCCCGGTCC
TTACCGTGAGTGACGATTTCGATCAGGCAAGCGGCGTCTACACGCTGACCGTGACGCAGAGCTGCCCCCCCACCCCGGGG
CAGGCCGAGAAGGAGCCGTTCCACATACCGCTCTCCATCGGGCTTTTGAACCGGCAGGGGCGCGAGCTGCCGCTGCAGCT
TGAGGGAGAGAAGAGCCAGGGAGCGATCACCAGGGTGCTGGAGCTGCGCCAAGAGACGCAAAGCTTCCGGTTCACCGGGA
TAGCCTCCAAGCCGGTGCCGTCTCTCTTGCGGAACTTCTCCGCCCCGGTGAAGCTCGTGTACCCCTACAGCCAAGACGAC
CTCACCTTGCTGATGACCAGCGACAGCGATCCCTTCGTGCGCTGGGAGGCGGGGCAGGTGCAGGCGGTGCAGGTGATCAT
GGGGCTGGTGCGCGAGATACAGGCGGGGGGGACTCCGACGGTGCCGGAAGCCTTCATCGGCTCCTTCGGCACGCTCCTTA
CCGACCAGCGGCAGGACCGCGCCTTCCTAGCCGAGGCGCTCACCCTCCCCGCCGAGGGCTATCTCGCCGAGCAGATGAAG
GTAATCGACCCGGCCGCCATTCATGAGGCGCGGGAACTGGTGCGCGCGACGGTGGGCGAGCGGCTGCGGGCGCAGTTGGT
GGGGGCGCGCGCGGCGTGCGCCCCCAAGTCCCCTTACCACCCCGACGACGGCCTCGCCGGTTGCCGCAGGCTCAAGAACC
TCTGCCTCTCCTACCTGATGGCGCCCGGATCCAGGGAGGCGATAGGCATGGCGATGGAACAGTTTAAGAACGCCGACAAC
ATGACCGACAGCCTTGGCGCGCTCGCCACGCTGGCCGGCTGCGACTGCCCCGAGCGCGAGGAGGCGCTGGAGGCCTTCTA
CCGGAAATGGCGCGACGACCGCGGCGTCATCGACAAGTGGTTCAGCCTGCAGGCGACTTCCCGTCTGCCGCAGACGCTCG
ACCGGGTCCTCGAGCTTTTGGACCACCCCGACTTCGACATCCGGAACCCCAACCGGGTCCGCTCTTTGGTCGGCGCCTTC
AGCCAGGCGAACCAGGTCCGCTTCCACGACGCCGAAGGAAGGGGGTACCGCTTCTTGGGCGACCAGATCCTGCGCCTGAA
CGGCATCAACCCGCAGATCGCGGCCCGCATGCTGACCCCCTTCAGCCGCTGGCGGCGCTTCGACGCGGGGCGGCAGGAGT
TGATGAAAAAGGAGCTGGAGAGGATCTTAGCCGAACCGGGCTTGGCGCGGGACGTCTACGAGCTCGCGGCGAAGAGCTTG
TAG

Upstream 100 bases:

>100_bases
GCTGAAAACCAACCCCTCGACGTGCTAAGACATTGAAAACAATTGCTCGCGCCGGTACAATACTTCCTTTGCCATTCCTA
CATCCTTTGAGAGGGAGCCT

Downstream 100 bases:

>100_bases
ATAGGGTTACATCGCAGACGCAAAGAGGGCCGGAGATTTCCCCGGTCCTCTTTGCTTTTGTGGAGAGCGTTCCTAGATCC
ACCGTCTCTTTTTGAAATAG

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 880; Mature: 880

Protein sequence:

>880_residues
MHTCQHQTVYQKDYSAPDYLVETVELSFDLDPELTWVASRLKIRSNYDRAQGLRPLVLDGEELTLVSLKLDGVELEPARY
TAGDGALTVTDPPESFLLEVTTQISPKANSALSGLYASGPMLCTQCEAEGFRRITYFTDRPDVMAVYTVILKADKGSCPV
LLANGNLVEKGDLPDGRHFATWHDPFKKPSYLFAVVAGDLVHISDRFTTMSGRQVNLEIYVEEKNQGKCDHALRSLIEAM
RWDEEQFGREYDLDTYMVVAVDDFNMGAMENKGLNVFNSRYVLASPETATDDDYQAIEEVIGHEYFHNWTGNRITCRDWF
QLSLKEGLTIFRDQEFSADMQSRPVKRIADVRLLRSSQFPEDASPLAHPVRPDSYVEINNFYSMTVYHKGGEVIRMLQTL
LGREAFRAGMDLYFERHDGQAVRVDEFVQAMADAGKRDLSQFMRWYNQSGTPVLTVSDDFDQASGVYTLTVTQSCPPTPG
QAEKEPFHIPLSIGLLNRQGRELPLQLEGEKSQGAITRVLELRQETQSFRFTGIASKPVPSLLRNFSAPVKLVYPYSQDD
LTLLMTSDSDPFVRWEAGQVQAVQVIMGLVREIQAGGTPTVPEAFIGSFGTLLTDQRQDRAFLAEALTLPAEGYLAEQMK
VIDPAAIHEARELVRATVGERLRAQLVGARAACAPKSPYHPDDGLAGCRRLKNLCLSYLMAPGSREAIGMAMEQFKNADN
MTDSLGALATLAGCDCPEREEALEAFYRKWRDDRGVIDKWFSLQATSRLPQTLDRVLELLDHPDFDIRNPNRVRSLVGAF
SQANQVRFHDAEGRGYRFLGDQILRLNGINPQIAARMLTPFSRWRRFDAGRQELMKKELERILAEPGLARDVYELAAKSL

Sequences:

>Translated_880_residues
MHTCQHQTVYQKDYSAPDYLVETVELSFDLDPELTWVASRLKIRSNYDRAQGLRPLVLDGEELTLVSLKLDGVELEPARY
TAGDGALTVTDPPESFLLEVTTQISPKANSALSGLYASGPMLCTQCEAEGFRRITYFTDRPDVMAVYTVILKADKGSCPV
LLANGNLVEKGDLPDGRHFATWHDPFKKPSYLFAVVAGDLVHISDRFTTMSGRQVNLEIYVEEKNQGKCDHALRSLIEAM
RWDEEQFGREYDLDTYMVVAVDDFNMGAMENKGLNVFNSRYVLASPETATDDDYQAIEEVIGHEYFHNWTGNRITCRDWF
QLSLKEGLTIFRDQEFSADMQSRPVKRIADVRLLRSSQFPEDASPLAHPVRPDSYVEINNFYSMTVYHKGGEVIRMLQTL
LGREAFRAGMDLYFERHDGQAVRVDEFVQAMADAGKRDLSQFMRWYNQSGTPVLTVSDDFDQASGVYTLTVTQSCPPTPG
QAEKEPFHIPLSIGLLNRQGRELPLQLEGEKSQGAITRVLELRQETQSFRFTGIASKPVPSLLRNFSAPVKLVYPYSQDD
LTLLMTSDSDPFVRWEAGQVQAVQVIMGLVREIQAGGTPTVPEAFIGSFGTLLTDQRQDRAFLAEALTLPAEGYLAEQMK
VIDPAAIHEARELVRATVGERLRAQLVGARAACAPKSPYHPDDGLAGCRRLKNLCLSYLMAPGSREAIGMAMEQFKNADN
MTDSLGALATLAGCDCPEREEALEAFYRKWRDDRGVIDKWFSLQATSRLPQTLDRVLELLDHPDFDIRNPNRVRSLVGAF
SQANQVRFHDAEGRGYRFLGDQILRLNGINPQIAARMLTPFSRWRRFDAGRQELMKKELERILAEPGLARDVYELAAKSL
>Mature_880_residues
MHTCQHQTVYQKDYSAPDYLVETVELSFDLDPELTWVASRLKIRSNYDRAQGLRPLVLDGEELTLVSLKLDGVELEPARY
TAGDGALTVTDPPESFLLEVTTQISPKANSALSGLYASGPMLCTQCEAEGFRRITYFTDRPDVMAVYTVILKADKGSCPV
LLANGNLVEKGDLPDGRHFATWHDPFKKPSYLFAVVAGDLVHISDRFTTMSGRQVNLEIYVEEKNQGKCDHALRSLIEAM
RWDEEQFGREYDLDTYMVVAVDDFNMGAMENKGLNVFNSRYVLASPETATDDDYQAIEEVIGHEYFHNWTGNRITCRDWF
QLSLKEGLTIFRDQEFSADMQSRPVKRIADVRLLRSSQFPEDASPLAHPVRPDSYVEINNFYSMTVYHKGGEVIRMLQTL
LGREAFRAGMDLYFERHDGQAVRVDEFVQAMADAGKRDLSQFMRWYNQSGTPVLTVSDDFDQASGVYTLTVTQSCPPTPG
QAEKEPFHIPLSIGLLNRQGRELPLQLEGEKSQGAITRVLELRQETQSFRFTGIASKPVPSLLRNFSAPVKLVYPYSQDD
LTLLMTSDSDPFVRWEAGQVQAVQVIMGLVREIQAGGTPTVPEAFIGSFGTLLTDQRQDRAFLAEALTLPAEGYLAEQMK
VIDPAAIHEARELVRATVGERLRAQLVGARAACAPKSPYHPDDGLAGCRRLKNLCLSYLMAPGSREAIGMAMEQFKNADN
MTDSLGALATLAGCDCPEREEALEAFYRKWRDDRGVIDKWFSLQATSRLPQTLDRVLELLDHPDFDIRNPNRVRSLVGAF
SQANQVRFHDAEGRGYRFLGDQILRLNGINPQIAARMLTPFSRWRRFDAGRQELMKKELERILAEPGLARDVYELAAKSL

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI132814467, Length=379, Percent_Identity=25.3298153034301, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI158937236, Length=386, Percent_Identity=25.3886010362694, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI61742777, Length=325, Percent_Identity=25.8461538461538, Blast_Score=113, Evalue=9e-25,
Organism=Homo sapiens, GI61742775, Length=323, Percent_Identity=26.3157894736842, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI310123622, Length=307, Percent_Identity=27.0358306188925, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI94818891, Length=321, Percent_Identity=25.8566978193146, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI94818901, Length=324, Percent_Identity=25.6172839506173, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI310133497, Length=307, Percent_Identity=27.3615635179153, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI194306629, Length=304, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI11641261, Length=304, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI4505029, Length=412, Percent_Identity=25.9708737864078, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI157266300, Length=375, Percent_Identity=25.0666666666667, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI194239713, Length=356, Percent_Identity=23.876404494382, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI7019561, Length=309, Percent_Identity=26.2135922330097, Blast_Score=86, Evalue=2e-16,
Organism=Escherichia coli, GI1787163, Length=880, Percent_Identity=49.7727272727273, Blast_Score=842, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989076, Length=404, Percent_Identity=26.7326732673267, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71989071, Length=404, Percent_Identity=26.7326732673267, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17569225, Length=421, Percent_Identity=27.0783847980998, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115533278, Length=378, Percent_Identity=26.7195767195767, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115533276, Length=378, Percent_Identity=26.7195767195767, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17569221, Length=344, Percent_Identity=26.453488372093, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI133903840, Length=383, Percent_Identity=24.8041775456919, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17544504, Length=428, Percent_Identity=26.6355140186916, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193206928, Length=356, Percent_Identity=27.247191011236, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193206926, Length=356, Percent_Identity=27.247191011236, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565628, Length=298, Percent_Identity=26.1744966442953, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71990873, Length=431, Percent_Identity=22.969837587007, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321837, Length=426, Percent_Identity=27.2300469483568, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI9755335, Length=351, Percent_Identity=27.0655270655271, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6324283, Length=323, Percent_Identity=22.9102167182663, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24655257, Length=413, Percent_Identity=27.6029055690073, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24655252, Length=413, Percent_Identity=27.6029055690073, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24655274, Length=413, Percent_Identity=27.6029055690073, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24655260, Length=413, Percent_Identity=27.6029055690073, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24655265, Length=413, Percent_Identity=27.6029055690073, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24655268, Length=413, Percent_Identity=27.6029055690073, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24646514, Length=381, Percent_Identity=26.7716535433071, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646516, Length=363, Percent_Identity=26.4462809917355, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646518, Length=363, Percent_Identity=26.4462809917355, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24651025, Length=341, Percent_Identity=25.5131964809384, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24651023, Length=341, Percent_Identity=25.5131964809384, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24651021, Length=341, Percent_Identity=25.5131964809384, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21358341, Length=256, Percent_Identity=29.6875, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646510, Length=361, Percent_Identity=26.5927977839335, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24646512, Length=361, Percent_Identity=26.5927977839335, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24651016, Length=192, Percent_Identity=33.8541666666667, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24648786, Length=398, Percent_Identity=25.1256281407035, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550850, Length=352, Percent_Identity=25.5681818181818, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24650973, Length=352, Percent_Identity=25.5681818181818, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI161078673, Length=409, Percent_Identity=25.9168704156479, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571901, Length=410, Percent_Identity=25.8536585365854, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221379089, Length=331, Percent_Identity=24.773413897281, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28571792, Length=370, Percent_Identity=25.9459459459459, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24648790, Length=313, Percent_Identity=22.6837060702875, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 99007; Mature: 99007

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTCQHQTVYQKDYSAPDYLVETVELSFDLDPELTWVASRLKIRSNYDRAQGLRPLVLDG
CCCCCCCHHHHCCCCCHHHEEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHCCCCEEECC
EELTLVSLKLDGVELEPARYTAGDGALTVTDPPESFLLEVTTQISPKANSALSGLYASGP
CCEEEEEEEECCEEECCCEEECCCCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHCCCC
MLCTQCEAEGFRRITYFTDRPDVMAVYTVILKADKGSCPVLLANGNLVEKGDLPDGRHFA
EEEEECCCCCCEEEEEECCCCCHHEEEEEHEECCCCCCCEEEECCCEEECCCCCCCCEEC
TWHDPFKKPSYLFAVVAGDLVHISDRFTTMSGRQVNLEIYVEEKNQGKCDHALRSLIEAM
CCCCCCCCCCEEEEEECCCEEEECCCEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHH
RWDEEQFGREYDLDTYMVVAVDDFNMGAMENKGLNVFNSRYVLASPETATDDDYQAIEEV
CCCHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCEECCEEEEECCCCCCCCHHHHHHHH
IGHEYFHNWTGNRITCRDWFQLSLKEGLTIFRDQEFSADMQSRPVKRIADVRLLRSSQFP
HHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCHHHCCHHHHHHHHHHHCCCCC
EDASPLAHPVRPDSYVEINNFYSMTVYHKGGEVIRMLQTLLGREAFRAGMDLYFERHDGQ
CCCCCCCCCCCCCCEEEECCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
AVRVDEFVQAMADAGKRDLSQFMRWYNQSGTPVLTVSDDFDQASGVYTLTVTQSCPPTPG
EEEHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCC
QAEKEPFHIPLSIGLLNRQGRELPLQLEGEKSQGAITRVLELRQETQSFRFTGIASKPVP
CCCCCCEEEEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCHH
SLLRNFSAPVKLVYPYSQDDLTLLMTSDSDPFVRWEAGQVQAVQVIMGLVREIQAGGTPT
HHHHCCCCCEEEEECCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCC
VPEAFIGSFGTLLTDQRQDRAFLAEALTLPAEGYLAEQMKVIDPAAIHEARELVRATVGE
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLRAQLVGARAACAPKSPYHPDDGLAGCRRLKNLCLSYLMAPGSREAIGMAMEQFKNADN
HHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
MTDSLGALATLAGCDCPEREEALEAFYRKWRDDRGVIDKWFSLQATSRLPQTLDRVLELL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DHPDFDIRNPNRVRSLVGAFSQANQVRFHDAEGRGYRFLGDQILRLNGINPQIAARMLTP
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCEEEEECCCCHHHHHHHHHH
FSRWRRFDAGRQELMKKELERILAEPGLARDVYELAAKSL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MHTCQHQTVYQKDYSAPDYLVETVELSFDLDPELTWVASRLKIRSNYDRAQGLRPLVLDG
CCCCCCCHHHHCCCCCHHHEEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHCCCCEEECC
EELTLVSLKLDGVELEPARYTAGDGALTVTDPPESFLLEVTTQISPKANSALSGLYASGP
CCEEEEEEEECCEEECCCEEECCCCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHCCCC
MLCTQCEAEGFRRITYFTDRPDVMAVYTVILKADKGSCPVLLANGNLVEKGDLPDGRHFA
EEEEECCCCCCEEEEEECCCCCHHEEEEEHEECCCCCCCEEEECCCEEECCCCCCCCEEC
TWHDPFKKPSYLFAVVAGDLVHISDRFTTMSGRQVNLEIYVEEKNQGKCDHALRSLIEAM
CCCCCCCCCCEEEEEECCCEEEECCCEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHH
RWDEEQFGREYDLDTYMVVAVDDFNMGAMENKGLNVFNSRYVLASPETATDDDYQAIEEV
CCCHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCEECCEEEEECCCCCCCCHHHHHHHH
IGHEYFHNWTGNRITCRDWFQLSLKEGLTIFRDQEFSADMQSRPVKRIADVRLLRSSQFP
HHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCCHHHCCHHHHHHHHHHHCCCCC
EDASPLAHPVRPDSYVEINNFYSMTVYHKGGEVIRMLQTLLGREAFRAGMDLYFERHDGQ
CCCCCCCCCCCCCCEEEECCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
AVRVDEFVQAMADAGKRDLSQFMRWYNQSGTPVLTVSDDFDQASGVYTLTVTQSCPPTPG
EEEHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCC
QAEKEPFHIPLSIGLLNRQGRELPLQLEGEKSQGAITRVLELRQETQSFRFTGIASKPVP
CCCCCCEEEEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCCCHH
SLLRNFSAPVKLVYPYSQDDLTLLMTSDSDPFVRWEAGQVQAVQVIMGLVREIQAGGTPT
HHHHCCCCCEEEEECCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCC
VPEAFIGSFGTLLTDQRQDRAFLAEALTLPAEGYLAEQMKVIDPAAIHEARELVRATVGE
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
RLRAQLVGARAACAPKSPYHPDDGLAGCRRLKNLCLSYLMAPGSREAIGMAMEQFKNADN
HHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
MTDSLGALATLAGCDCPEREEALEAFYRKWRDDRGVIDKWFSLQATSRLPQTLDRVLELL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DHPDFDIRNPNRVRSLVGAFSQANQVRFHDAEGRGYRFLGDQILRLNGINPQIAARMLTP
CCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCEEEEECCCCHHHHHHHHHH
FSRWRRFDAGRQELMKKELERILAEPGLARDVYELAAKSL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]