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The map label for this gene is prx-4 [H]

Identifier: 197116621

GI number: 197116621

Start: 261384

End: 261860

Strand: Direct

Name: prx-4 [H]

Synonym: Gbem_0221

Alternate gene names: 197116621

Gene position: 261384-261860 (Clockwise)

Preceding gene: 197116619

Following gene: 197116623

Centisome position: 5.66

GC content: 57.23

Gene sequence:

>477_bases
ATGTTTTTGGAAGGACAACCCGCACCTAATTTCTCCCTGCAGGGAAGCGATGCGAAAACCCACACTCTCAAGGATTACGC
CGGAAGAATCCTGGTCCTCTTCTTCTATCCGAGGGACAACACGCCCGGCTGCACCGCAGAGGCGGTCGGATTCGCCAAAC
TGCAGCCGCTGTTCGAGCAACTGGGCGCGGTGCTGGTAGGGGTGAGCAAGGATTCACTCAAATCACACGCGAAATTCAGC
GCCGACTTCAAACTCCCCTTCACCCTGCTCTCCGACCCAGATGCTTCCGTGATGAAGGCCTACGGCGCCTATGGGGAGAA
GCAGCAGTACGGCAAGACCACCATAGGCAGCATCCGCTCGACCGTGGTCATCTCCCCCGACGGGATGGTGATCAAGCACT
GGCCCAAGATTCCCAAGGCATCGGAACATCCGGACAAGGTGCTGGATTTTTTCAAGATGCTGGCCAAGGGAAGGTAG

Upstream 100 bases:

>100_bases
CTCTGCTATGGTTTACCCGTTCATGAAAGGCGGGACCCGCAGTCGTTCATGCTGCGCCAATTCGCCCCAATCTATAAAGC
AGAAGCAGACAGGAGGACGC

Downstream 100 bases:

>100_bases
CGTCAGGGCCTAGGCCAAAGTAAGGGCGAAGCGTCGAAGGCTCCCGGGGATGAACCTCGGGGGCCTTTCCCGTGTTGAGA
GCCCCCCCTCTTGCCCCATC

Product: peroxiredoxin

Products: NA

Alternate protein names: Bacterioferritin comigratory protein homolog; Thioredoxin reductase [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MFLEGQPAPNFSLQGSDAKTHTLKDYAGRILVLFFYPRDNTPGCTAEAVGFAKLQPLFEQLGAVLVGVSKDSLKSHAKFS
ADFKLPFTLLSDPDASVMKAYGAYGEKQQYGKTTIGSIRSTVVISPDGMVIKHWPKIPKASEHPDKVLDFFKMLAKGR

Sequences:

>Translated_158_residues
MFLEGQPAPNFSLQGSDAKTHTLKDYAGRILVLFFYPRDNTPGCTAEAVGFAKLQPLFEQLGAVLVGVSKDSLKSHAKFS
ADFKLPFTLLSDPDASVMKAYGAYGEKQQYGKTTIGSIRSTVVISPDGMVIKHWPKIPKASEHPDKVLDFFKMLAKGR
>Mature_158_residues
MFLEGQPAPNFSLQGSDAKTHTLKDYAGRILVLFFYPRDNTPGCTAEAVGFAKLQPLFEQLGAVLVGVSKDSLKSHAKFS
ADFKLPFTLLSDPDASVMKAYGAYGEKQQYGKTTIGSIRSTVVISPDGMVIKHWPKIPKASEHPDKVLDFFKMLAKGR

Specific function: Unknown

COG id: COG1225

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788825, Length=148, Percent_Identity=37.1621621621622, Blast_Score=97, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25153706, Length=135, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322180, Length=119, Percent_Identity=39.4957983193277, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 17311; Mature: 17311

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLEGQPAPNFSLQGSDAKTHTLKDYAGRILVLFFYPRDNTPGCTAEAVGFAKLQPLFEQ
CCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LGAVLVGVSKDSLKSHAKFSADFKLPFTLLSDPDASVMKAYGAYGEKQQYGKTTIGSIRS
HHHHEECCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHCCCCCCHHHCCCHHCCCCE
TVVISPDGMVIKHWPKIPKASEHPDKVLDFFKMLAKGR
EEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFLEGQPAPNFSLQGSDAKTHTLKDYAGRILVLFFYPRDNTPGCTAEAVGFAKLQPLFEQ
CCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LGAVLVGVSKDSLKSHAKFSADFKLPFTLLSDPDASVMKAYGAYGEKQQYGKTTIGSIRS
HHHHEECCCHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHCCCCCCHHHCCCHHCCCCE
TVVISPDGMVIKHWPKIPKASEHPDKVLDFFKMLAKGR
EEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]