Click here to switch to the map view.

The map label for this gene is arcB [H]

Identifier: 197116465

GI number: 197116465

Start: 79674

End: 81410

Strand: Reverse

Name: arcB [H]

Synonym: Gbem_0065

Alternate gene names: 197116465

Gene position: 81410-79674 (Counterclockwise)

Preceding gene: 197116482

Following gene: 197116464

Centisome position: 1.76

GC content: 61.66

Gene sequence:

>1737_bases
ATGGGAAAGGAACGAGATATTCTGATCGTCGACGACAACCAGGTGGTCTGCGATGTTCTGACTGAACTATTCCGCAACGA
GGGGTTCGACAGTTGGGGTGTTGCCACGGGCGAGGCGTGCCTCGATGAAGTGACCCGCGCTTCCTGCAAGCTGGTGATGC
TGGATGTGCGCCTCCCCGGGATCAGCGGCATCGAGGTTCTCGAAGCCATCCGGCGTGACCACCCTAGGACGGAAGTGATC
ATCATGACCAGCCATGTATCGCTGGAGACGGCGGTCCAGGCCCTGCGCCTGGGAGCCCAGGATTACCTTTTCAAGCCCTT
CGACGACCTGGAGATGGTGATCGCCACCGTTAACAAGGCGCTGGAGCGCCGCCGCCTCGTCGAGGAGCGCGACAAGCTGG
TGCGCACCCTGACCGACCTGGCCATCGAGAACGGCCGCATCCTCGCCGAATGCCGCCGGGTAAACAGCAGCCTTGAGGAA
AAGGTGGCGCAGCGGACCGCCGAACTTTCCAAGTCGAACCTGCAGCAAAAGGCCATCATCGCCGAACTGCACGAAGCGAA
GGAAGCCGCCGAAGCAGCCAACCGGGCCAAGTCGCAATTTCTCGCCAACATGAGCCACGAGATCCGCACGCCGATGAACG
GTGTCCTCGGCATGGCCGAACTCCTGCTGCACTCAGAGCTCGACGAGAAGCAGAAGAGCTACGTCAAGATACTGCACCAA
TCCGGCGAATCGCTCCTCGGCATCATCAACGACATCCTCAACATCTCCAAGATCGAGGCGGGAAGGCTGGAGATAGAGAG
GATTCCTTTCGATCTGCACGAAACTGCGCGCGGCGCGGTGGAACTCTACCGGGAAGTCGGCCGGCGCAAGGGCGTAGCGG
TGGAGCTGCAGATCGAGGAGGACGTTCCGCGCTGCGTCGTCGGTGACCCGAGCCGCCTGCGGCAGGTCCTGATCAACGTC
GTCAACAACGGCTTGAAATTCACCGATAAGGGGTCGGTACAGGTTCGCGTCACCCTGGTGGAGCAGTACCAAAACGGGCA
GTACGTAGCCTTTGAGGTGAAGGACACGGGGATTGGGATACCCGCTGACTGCATCGGCGACATCTTCGGCTTATTCGCCC
AAGTGGACGGCTCGACCACGCGGAAGTACGGAGGGACCGGGTTGGGACTGGCGATAGCGAAGCAACTGGTTGAGCTGATG
GGGGGCGCAATAGGGGTAGAGAGCGAGCCGGGACAGGGCTCCACCTTCACTTTCATCGTCTTCCTGCACCGGCACGCCGA
CCAGACTACATGCGACGAGGACACGCCGGCCGAGCTGGATAATCCCATGGCAGCGGCTCGTGAGGTGCGGAAGTTCAACG
CCCGCGTGCTGCTGGCCGAAGACAACCCGGTCAATTGCGAGGTGGCCTTCGCCATGATCGCCGCGCTGGGGTGCCAGGTT
GACGTGGCCCAGGACGGAAGAGAAGCCGTCGAGGCCTTTACGCGCCAGCCGTACGACCTGATCTTCATGGATTGCCAGAT
GCCGGAGATGGACGGCTACCAGGCCACCCGAGCCATCCGCCAGCGGGAACTCGGCTCCGGCAGGCACACCACCGTGATCG
CACTAACCGCCCACGCCATGGCGGGAGCCAGGGAACATTGCCTCAGTGCAGGAATGGACGACTACCTCAGCAAACCTTTC
AACCTCGAACAGCTCCAGGAGCTGATCGTCAAATGGACCACCCCCCACCTCGCCTGA

Upstream 100 bases:

>100_bases
GTTTCATCTCCACTTCCCGCAGCGGGCAACCGGCAAGGGGTTGTTATCATCGTTCTTTTTGTTAGTATTTTCCAATGATA
TTTTAGCGAGGGAGACTTTC

Downstream 100 bases:

>100_bases
TCGACCTGTGCGCCGACTTTTAGTGCAAAAGCATCTCCTCGCTTTTGGGAAAAAGGTGCCATCACGTCCCCCCCTTTGCG
AAGGGGGGGCAGGGGGGATT

Product: response receiver histidine kinase response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MGKERDILIVDDNQVVCDVLTELFRNEGFDSWGVATGEACLDEVTRASCKLVMLDVRLPGISGIEVLEAIRRDHPRTEVI
IMTSHVSLETAVQALRLGAQDYLFKPFDDLEMVIATVNKALERRRLVEERDKLVRTLTDLAIENGRILAECRRVNSSLEE
KVAQRTAELSKSNLQQKAIIAELHEAKEAAEAANRAKSQFLANMSHEIRTPMNGVLGMAELLLHSELDEKQKSYVKILHQ
SGESLLGIINDILNISKIEAGRLEIERIPFDLHETARGAVELYREVGRRKGVAVELQIEEDVPRCVVGDPSRLRQVLINV
VNNGLKFTDKGSVQVRVTLVEQYQNGQYVAFEVKDTGIGIPADCIGDIFGLFAQVDGSTTRKYGGTGLGLAIAKQLVELM
GGAIGVESEPGQGSTFTFIVFLHRHADQTTCDEDTPAELDNPMAAAREVRKFNARVLLAEDNPVNCEVAFAMIAALGCQV
DVAQDGREAVEAFTRQPYDLIFMDCQMPEMDGYQATRAIRQRELGSGRHTTVIALTAHAMAGAREHCLSAGMDDYLSKPF
NLEQLQELIVKWTTPHLA

Sequences:

>Translated_578_residues
MGKERDILIVDDNQVVCDVLTELFRNEGFDSWGVATGEACLDEVTRASCKLVMLDVRLPGISGIEVLEAIRRDHPRTEVI
IMTSHVSLETAVQALRLGAQDYLFKPFDDLEMVIATVNKALERRRLVEERDKLVRTLTDLAIENGRILAECRRVNSSLEE
KVAQRTAELSKSNLQQKAIIAELHEAKEAAEAANRAKSQFLANMSHEIRTPMNGVLGMAELLLHSELDEKQKSYVKILHQ
SGESLLGIINDILNISKIEAGRLEIERIPFDLHETARGAVELYREVGRRKGVAVELQIEEDVPRCVVGDPSRLRQVLINV
VNNGLKFTDKGSVQVRVTLVEQYQNGQYVAFEVKDTGIGIPADCIGDIFGLFAQVDGSTTRKYGGTGLGLAIAKQLVELM
GGAIGVESEPGQGSTFTFIVFLHRHADQTTCDEDTPAELDNPMAAAREVRKFNARVLLAEDNPVNCEVAFAMIAALGCQV
DVAQDGREAVEAFTRQPYDLIFMDCQMPEMDGYQATRAIRQRELGSGRHTTVIALTAHAMAGAREHCLSAGMDDYLSKPF
NLEQLQELIVKWTTPHLA
>Mature_577_residues
GKERDILIVDDNQVVCDVLTELFRNEGFDSWGVATGEACLDEVTRASCKLVMLDVRLPGISGIEVLEAIRRDHPRTEVII
MTSHVSLETAVQALRLGAQDYLFKPFDDLEMVIATVNKALERRRLVEERDKLVRTLTDLAIENGRILAECRRVNSSLEEK
VAQRTAELSKSNLQQKAIIAELHEAKEAAEAANRAKSQFLANMSHEIRTPMNGVLGMAELLLHSELDEKQKSYVKILHQS
GESLLGIINDILNISKIEAGRLEIERIPFDLHETARGAVELYREVGRRKGVAVELQIEEDVPRCVVGDPSRLRQVLINVV
NNGLKFTDKGSVQVRVTLVEQYQNGQYVAFEVKDTGIGIPADCIGDIFGLFAQVDGSTTRKYGGTGLGLAIAKQLVELMG
GAIGVESEPGQGSTFTFIVFLHRHADQTTCDEDTPAELDNPMAAAREVRKFNARVLLAEDNPVNCEVAFAMIAALGCQVD
VAQDGREAVEAFTRQPYDLIFMDCQMPEMDGYQATRAIRQRELGSGRHTTVIALTAHAMAGAREHCLSAGMDDYLSKPFN
LEQLQELIVKWTTPHLA

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=397, Percent_Identity=37.27959697733, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI1789149, Length=265, Percent_Identity=42.2641509433962, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1788713, Length=393, Percent_Identity=32.5699745547074, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI87081816, Length=425, Percent_Identity=32.9411764705882, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=41.9087136929461, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=28.9473684210526, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=27.0491803278689, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=42.3728813559322, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=29.3333333333333, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=166, Percent_Identity=34.3373493975904, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=27.6785714285714, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=232, Percent_Identity=25, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786912, Length=252, Percent_Identity=25.3968253968254, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790299, Length=115, Percent_Identity=33.9130434782609, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=28.6343612334802, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082012, Length=111, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=27.3858921161826, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=135, Percent_Identity=32.5925925925926, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789402, Length=108, Percent_Identity=35.1851851851852, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=124, Percent_Identity=36.2903225806452, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322000, Length=118, Percent_Identity=33.0508474576271, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63963; Mature: 63832

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKERDILIVDDNQVVCDVLTELFRNEGFDSWGVATGEACLDEVTRASCKLVMLDVRLPG
CCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCC
ISGIEVLEAIRRDHPRTEVIIMTSHVSLETAVQALRLGAQDYLFKPFDDLEMVIATVNKA
CCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHH
LERRRLVEERDKLVRTLTDLAIENGRILAECRRVNSSLEEKVAQRTAELSKSNLQQKAII
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELHEAKEAAEAANRAKSQFLANMSHEIRTPMNGVLGMAELLLHSELDEKQKSYVKILHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGESLLGIINDILNISKIEAGRLEIERIPFDLHETARGAVELYREVGRRKGVAVELQIEE
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
DVPRCVVGDPSRLRQVLINVVNNGLKFTDKGSVQVRVTLVEQYQNGQYVAFEVKDTGIGI
CCCCEECCCHHHHHHHHHHHHHCCCEEECCCCEEEEEEEEEHHCCCCEEEEEEECCCCCC
PADCIGDIFGLFAQVDGSTTRKYGGTGLGLAIAKQLVELMGGAIGVESEPGQGSTFTFIV
CHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
FLHRHADQTTCDEDTPAELDNPMAAAREVRKFNARVLLAEDNPVNCEVAFAMIAALGCQV
EEECCCCCCCCCCCCCHHCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCE
DVAQDGREAVEAFTRQPYDLIFMDCQMPEMDGYQATRAIRQRELGSGRHTTVIALTAHAM
EECCCHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHH
AGAREHCLSAGMDDYLSKPFNLEQLQELIVKWTTPHLA
HHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GKERDILIVDDNQVVCDVLTELFRNEGFDSWGVATGEACLDEVTRASCKLVMLDVRLPG
CCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCC
ISGIEVLEAIRRDHPRTEVIIMTSHVSLETAVQALRLGAQDYLFKPFDDLEMVIATVNKA
CCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHH
LERRRLVEERDKLVRTLTDLAIENGRILAECRRVNSSLEEKVAQRTAELSKSNLQQKAII
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELHEAKEAAEAANRAKSQFLANMSHEIRTPMNGVLGMAELLLHSELDEKQKSYVKILHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGESLLGIINDILNISKIEAGRLEIERIPFDLHETARGAVELYREVGRRKGVAVELQIEE
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
DVPRCVVGDPSRLRQVLINVVNNGLKFTDKGSVQVRVTLVEQYQNGQYVAFEVKDTGIGI
CCCCEECCCHHHHHHHHHHHHHCCCEEECCCCEEEEEEEEEHHCCCCEEEEEEECCCCCC
PADCIGDIFGLFAQVDGSTTRKYGGTGLGLAIAKQLVELMGGAIGVESEPGQGSTFTFIV
CHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
FLHRHADQTTCDEDTPAELDNPMAAAREVRKFNARVLLAEDNPVNCEVAFAMIAALGCQV
EEECCCCCCCCCCCCCHHCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCE
DVAQDGREAVEAFTRQPYDLIFMDCQMPEMDGYQATRAIRQRELGSGRHTTVIALTAHAM
EECCCHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEHHHH
AGAREHCLSAGMDDYLSKPFNLEQLQELIVKWTTPHLA
HHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]