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The map label for this gene is mdtA [H]

Identifier: 197116464

GI number: 197116464

Start: 78069

End: 79202

Strand: Reverse

Name: mdtA [H]

Synonym: Gbem_0064

Alternate gene names: 197116464

Gene position: 79202-78069 (Counterclockwise)

Preceding gene: 197116465

Following gene: 197116463

Centisome position: 1.72

GC content: 62.08

Gene sequence:

>1134_bases
ATGTTTCCAGCAACAAGCCGCAGGTTCGTACAAGCAGTCAGCCTCGTAACAGTTCTTCTTTCCTTGTCCGCATGCTCCAC
CCAAAAAGAGAAACCGAAGGCCAAGCCCCCGGTGCCGGTGGCCGTCGCTACAGCGGCAAGAAAAGACGTCCCGGTGCAAT
TGAAGGCGATAGGGAACATCGAGCCATTTAACTCGGTCGCCATCAAGTCGCAGGTGAACGGCCAGATAGCGAAGGTCCAT
TTCCAGGACGGCTGCGACGTGCAGAAGGGGGCCTTGCTCGTCACCCTGCAACCGGAGTCGTTCCAGGCGGCTCTGAACCA
AAGCGAGGCGGCTCTCACGCGGGATCTCGCCCAAGCCAAGTTCGCCAAGGAGCAGGCGGAACGCTACCGGCAGTTGGTCG
CGGAAGGTATCGTCACCAAGGATCAGTACGATCAGCTGCGCACCAACGCCGAATCGGCCGCCGCGGCCGTGGCCGCGGAC
CGCGCCGCCATCGCCAACGCCAAAATCCAGCGCAACTATTGCTACATCCGCTCGCCCATCTCCGGCAGGACCGGAAACCT
TGCGCTGCAACTCGGCAACCTGGTCAAGGCGAACGACCTGACTCTCGTCACGATCAATCAGATCAGCCCTATCTACGCGA
CTTTCTCCATCCCCGAGAAGAGCCTTCCCGAGGTGAAAAAAGCGATGGCGGGGCGCGCCCTGAAGATAGAGGCCGTCGTC
CCCAACGATCCGAACGGCAAGGAGACCGGCACCATCAGCTTCCTGGACAATGCCGTGAATAGCGCCACAGGGACCATCCG
ACTCAAAGGGGTCTTCGCCAACGCCGACCGCAAACTCTGGCCGGGGCAGTTCGTCGATGTGGTGATGACGCTCGGCGTGA
GGCGCGATGCGGTGGTCGTCCCGACTCAGGCGGTGCAGGTCGGCCAGCAGGGGCAGTACGTCTACGTCGTGAAGCCCGAC
AAGACGGCGGAGATGAGGTCGGTCACGGTAGCCGCGGAGCAGGCGGGGGAAAGCGTTATCGAGAAAGGCGTGGCCCCTGG
TGAAACCGTGGTGGTCAGCGGCCAGCTGCGACTGACGCCGGGCGCGAAGGTCGAGCTTCCCTCCAGCCAGCCTACAGCGG
TAAAAAGGCCATGA

Upstream 100 bases:

>100_bases
TCTTTCCCCGAGGATTTTAGTCGTATACTGGCGCCAATTTCAAAGCTTCCTCATTTAATTAAAATTACATCCGCTCAACG
CGGGAGTAAGGCGGGGGATA

Downstream 100 bases:

>100_bases
ACATAGCGGAGCTTTTCATCCGCCGGCCGATCATGACCTCGCTCGTCATGATCGCCATCCTCATCTTCGGGATCGCCGCC
TACCGGCTGCTGCCGGTGAA

Product: RND family efflux pump membrane fusion lipoprotein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MFPATSRRFVQAVSLVTVLLSLSACSTQKEKPKAKPPVPVAVATAARKDVPVQLKAIGNIEPFNSVAIKSQVNGQIAKVH
FQDGCDVQKGALLVTLQPESFQAALNQSEAALTRDLAQAKFAKEQAERYRQLVAEGIVTKDQYDQLRTNAESAAAAVAAD
RAAIANAKIQRNYCYIRSPISGRTGNLALQLGNLVKANDLTLVTINQISPIYATFSIPEKSLPEVKKAMAGRALKIEAVV
PNDPNGKETGTISFLDNAVNSATGTIRLKGVFANADRKLWPGQFVDVVMTLGVRRDAVVVPTQAVQVGQQGQYVYVVKPD
KTAEMRSVTVAAEQAGESVIEKGVAPGETVVVSGQLRLTPGAKVELPSSQPTAVKRP

Sequences:

>Translated_377_residues
MFPATSRRFVQAVSLVTVLLSLSACSTQKEKPKAKPPVPVAVATAARKDVPVQLKAIGNIEPFNSVAIKSQVNGQIAKVH
FQDGCDVQKGALLVTLQPESFQAALNQSEAALTRDLAQAKFAKEQAERYRQLVAEGIVTKDQYDQLRTNAESAAAAVAAD
RAAIANAKIQRNYCYIRSPISGRTGNLALQLGNLVKANDLTLVTINQISPIYATFSIPEKSLPEVKKAMAGRALKIEAVV
PNDPNGKETGTISFLDNAVNSATGTIRLKGVFANADRKLWPGQFVDVVMTLGVRRDAVVVPTQAVQVGQQGQYVYVVKPD
KTAEMRSVTVAAEQAGESVIEKGVAPGETVVVSGQLRLTPGAKVELPSSQPTAVKRP
>Mature_377_residues
MFPATSRRFVQAVSLVTVLLSLSACSTQKEKPKAKPPVPVAVATAARKDVPVQLKAIGNIEPFNSVAIKSQVNGQIAKVH
FQDGCDVQKGALLVTLQPESFQAALNQSEAALTRDLAQAKFAKEQAERYRQLVAEGIVTKDQYDQLRTNAESAAAAVAAD
RAAIANAKIQRNYCYIRSPISGRTGNLALQLGNLVKANDLTLVTINQISPIYATFSIPEKSLPEVKKAMAGRALKIEAVV
PNDPNGKETGTISFLDNAVNSATGTIRLKGVFANADRKLWPGQFVDVVMTLGVRRDAVVVPTQAVQVGQQGQYVYVVKPD
KTAEMRSVTVAAEQAGESVIEKGVAPGETVVVSGQLRLTPGAKVELPSSQPTAVKRP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=340, Percent_Identity=34.7058823529412, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1789929, Length=362, Percent_Identity=30.1104972375691, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786668, Length=369, Percent_Identity=28.9972899728997, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789665, Length=376, Percent_Identity=29.5212765957447, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40193; Mature: 40193

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPATSRRFVQAVSLVTVLLSLSACSTQKEKPKAKPPVPVAVATAARKDVPVQLKAIGNI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHCCCCCCEEEEEECCC
EPFNSVAIKSQVNGQIAKVHFQDGCDVQKGALLVTLQPESFQAALNQSEAALTRDLAQAK
CCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHH
FAKEQAERYRQLVAEGIVTKDQYDQLRTNAESAAAAVAADRAAIANAKIQRNYCYIRSPI
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCEEECCEEEEECCC
SGRTGNLALQLGNLVKANDLTLVTINQISPIYATFSIPEKSLPEVKKAMAGRALKIEAVV
CCCCCCEEEEECCEEEECCEEEEEECCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEEC
PNDPNGKETGTISFLDNAVNSATGTIRLKGVFANADRKLWPGQFVDVVMTLGVRRDAVVV
CCCCCCCCCEEEEEHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEE
PTQAVQVGQQGQYVYVVKPDKTAEMRSVTVAAEQAGESVIEKGVAPGETVVVSGQLRLTP
CHHHHHHCCCCCEEEEECCCCCCHHHEEEEHHHHHHHHHHHCCCCCCCEEEEECEEEECC
GAKVELPSSQPTAVKRP
CCEEECCCCCCCCCCCC
>Mature Secondary Structure
MFPATSRRFVQAVSLVTVLLSLSACSTQKEKPKAKPPVPVAVATAARKDVPVQLKAIGNI
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHCCCCCCEEEEEECCC
EPFNSVAIKSQVNGQIAKVHFQDGCDVQKGALLVTLQPESFQAALNQSEAALTRDLAQAK
CCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHH
FAKEQAERYRQLVAEGIVTKDQYDQLRTNAESAAAAVAADRAAIANAKIQRNYCYIRSPI
HHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCEEECCEEEEECCC
SGRTGNLALQLGNLVKANDLTLVTINQISPIYATFSIPEKSLPEVKKAMAGRALKIEAVV
CCCCCCEEEEECCEEEECCEEEEEECCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEEEC
PNDPNGKETGTISFLDNAVNSATGTIRLKGVFANADRKLWPGQFVDVVMTLGVRRDAVVV
CCCCCCCCCEEEEEHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEE
PTQAVQVGQQGQYVYVVKPDKTAEMRSVTVAAEQAGESVIEKGVAPGETVVVSGQLRLTP
CHHHHHHCCCCCEEEEECCCCCCHHHEEEEHHHHHHHHHHHCCCCCCCEEEEECEEEECC
GAKVELPSSQPTAVKRP
CCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA