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The map label for this gene is virA [H]

Identifier: 197116418

GI number: 197116418

Start: 25221

End: 26090

Strand: Direct

Name: virA [H]

Synonym: Gbem_0018

Alternate gene names: 197116418

Gene position: 25221-26090 (Clockwise)

Preceding gene: 197116417

Following gene: 197116419

Centisome position: 0.55

GC content: 63.33

Gene sequence:

>870_bases
ATGATGTCGCTTCGCGATTGGTGCCGCGACATATTAGCCAGCCACACCGAAGGCTCGTGTCCCGCCGGGGCAGGAAAGGA
CCCCCCCTCCCCTGCCGCCGAGGCTAAGCCGAATGAAGCCTTGCTCGCGCCCGACGAACTGGAAAAGCAGCTGCTGCAAG
TCCAGAAGCTTGCCGCGGTAGGCGTCCTGGCGGGGAGCATCGCGCACGACCTGAACAACCTCATGATGGGGATCAGCGGC
AACCTTGAACTCTTGCGCCAGGCAAAAGAACCGGACGCCGCCTCGCAAAAATACATGGACAACGCACTCGATGCCTCCAG
GCGCGCGGCGAACCTGAGCCGCCAGATGCTCGCCTTCTCCAGGAAAGGGAGTCAGGAGGTGAAGTCGGTCGATCTCAACC
GGCTGGTTGCCGAAAACCTGGAGCTGATGAAGGGGTCGATGCGCAAGGGCATCTCCCTCTCGGTTCGGTTGGAACCGGAG
CTTCCCCCTATAGAGGCGGAACCGGGCAAGATGCAGCAGCTGATCGTGAACCTGGTAACCAACGCGGCCGAGGCGCTAGG
GGAAACGGGCGCCATCGGCGTGTCGACGGGTGTGGGGGAGCTGCCTGCAGCGGAATTCACCTGGAGCCGAGTCGAGCCGA
AGCCGGCTTCCGGGCGCTTCGTGTTCATCGAGGTGTCAGACAGTGGCTGCGGGATGGACGGGGAAACCAGTGACCGTATG
TTCGACCCCTTATTCTCCACCAAGGCGGCCGGCAGAGGGTTGGGGCTTACCGCGGTGCACGCGATCGTGAAAGCGAGCGG
CGGCGCCATCCTCGCAGATACTGCCCCAGGGGAAGGGACCACGATCAGAGCCTTCCTTCCGGCCCCTTGA

Upstream 100 bases:

>100_bases
GTGGTGACTGCGAGACTGCAGCTTCACACTCAGTAAAGAGGCCGTTCGTCCCGTCGCAGCCCCCCAAGGGACGGCAGCGT
CAGCACGAGAAGGAAGGAAG

Downstream 100 bases:

>100_bases
TGAATAAAAAAAAGGGGACAGGCTACTTTTTGATTTGAAAAAGTAGCCTGTCCCCCTTTCCTGGATTTAAGAGAAAACTC
AAATGAATTGGCAGGTTTAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MMSLRDWCRDILASHTEGSCPAGAGKDPPSPAAEAKPNEALLAPDELEKQLLQVQKLAAVGVLAGSIAHDLNNLMMGISG
NLELLRQAKEPDAASQKYMDNALDASRRAANLSRQMLAFSRKGSQEVKSVDLNRLVAENLELMKGSMRKGISLSVRLEPE
LPPIEAEPGKMQQLIVNLVTNAAEALGETGAIGVSTGVGELPAAEFTWSRVEPKPASGRFVFIEVSDSGCGMDGETSDRM
FDPLFSTKAAGRGLGLTAVHAIVKASGGAILADTAPGEGTTIRAFLPAP

Sequences:

>Translated_289_residues
MMSLRDWCRDILASHTEGSCPAGAGKDPPSPAAEAKPNEALLAPDELEKQLLQVQKLAAVGVLAGSIAHDLNNLMMGISG
NLELLRQAKEPDAASQKYMDNALDASRRAANLSRQMLAFSRKGSQEVKSVDLNRLVAENLELMKGSMRKGISLSVRLEPE
LPPIEAEPGKMQQLIVNLVTNAAEALGETGAIGVSTGVGELPAAEFTWSRVEPKPASGRFVFIEVSDSGCGMDGETSDRM
FDPLFSTKAAGRGLGLTAVHAIVKASGGAILADTAPGEGTTIRAFLPAP
>Mature_289_residues
MMSLRDWCRDILASHTEGSCPAGAGKDPPSPAAEAKPNEALLAPDELEKQLLQVQKLAAVGVLAGSIAHDLNNLMMGISG
NLELLRQAKEPDAASQKYMDNALDASRRAANLSRQMLAFSRKGSQEVKSVDLNRLVAENLELMKGSMRKGISLSVRLEPE
LPPIEAEPGKMQQLIVNLVTNAAEALGETGAIGVSTGVGELPAAEFTWSRVEPKPASGRFVFIEVSDSGCGMDGETSDRM
FDPLFSTKAAGRGLGLTAVHAIVKASGGAILADTAPGEGTTIRAFLPAP

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=31.0483870967742, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=30.241935483871, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=26.9709543568465, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=26.1410788381743, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 30372; Mature: 30372

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSLRDWCRDILASHTEGSCPAGAGKDPPSPAAEAKPNEALLAPDELEKQLLQVQKLAAV
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHH
GVLAGSIAHDLNNLMMGISGNLELLRQAKEPDAASQKYMDNALDASRRAANLSRQMLAFS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKGSQEVKSVDLNRLVAENLELMKGSMRKGISLSVRLEPELPPIEAEPGKMQQLIVNLVT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
NAAEALGETGAIGVSTGVGELPAAEFTWSRVEPKPASGRFVFIEVSDSGCGMDGETSDRM
HHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHH
FDPLFSTKAAGRGLGLTAVHAIVKASGGAILADTAPGEGTTIRAFLPAP
HHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure
MMSLRDWCRDILASHTEGSCPAGAGKDPPSPAAEAKPNEALLAPDELEKQLLQVQKLAAV
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHH
GVLAGSIAHDLNNLMMGISGNLELLRQAKEPDAASQKYMDNALDASRRAANLSRQMLAFS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKGSQEVKSVDLNRLVAENLELMKGSMRKGISLSVRLEPELPPIEAEPGKMQQLIVNLVT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
NAAEALGETGAIGVSTGVGELPAAEFTWSRVEPKPASGRFVFIEVSDSGCGMDGETSDRM
HHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHH
FDPLFSTKAAGRGLGLTAVHAIVKASGGAILADTAPGEGTTIRAFLPAP
HHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3595559 [H]