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The map label for this gene is xseA [H]

Identifier: 197106405

GI number: 197106405

Start: 3365840

End: 3367303

Strand: Direct

Name: xseA [H]

Synonym: PHZ_c2944

Alternate gene names: 197106405

Gene position: 3365840-3367303 (Clockwise)

Preceding gene: 197106404

Following gene: 197106406

Centisome position: 84.22

GC content: 74.04

Gene sequence:

>1464_bases
ATGAGCGAAGCGCACGCCACCACCGACGCCGCCGGCCCCACGGATGGGAACGCCCGGCCCTACTCCGTCTCGGAGCTGGC
GTTCGCGCTGAAGCGGACGCTGGAGGACGCCTACGGCTTCGTGCGCCTGCGCGGCGAGCTGTCGAAGGTGACCCACCACT
CCAACGGTCACGTCTATCTGACGCTCAAGGACGACAAGGCGGCGATCGACGGCGTCGTCTGGAAGGGCCAGGTCCGCAAC
CTCTCCATCCGCCCCGAGCAGGGGATGGAGGTCGTGGTGACGGGCAAGATCACCGCCTATCCGCAGGGCTCGCGCTACCA
GATCGTCATCGAGACGATGGAAGCGGCCGGCGTCGGCGCCCTGCTGGCCCAGCTCGAGCGGCTGAAGGCGCGGCTGGCGG
GCGAGGGCCTGTTCGCGGCCGAGCGCAAGAAGCCGCTCCCCACCATGCCGTCCGTGGTGGGGGTGATCACCAGCCCGACG
GGCGCCGTCATCCGCGACATCCTGCACCGCATCCGCGACCGCTGGCCCTGCCACGTGGTGGTCTGGCCGGTGGTGGTGCA
GGGCGACGCGGCGGCCGGCCAGGTCTGCGCCGCGATCCGCGGCTTCTGCGCCCTGGATCCGGCGGGCCCGGTACCGCGCC
CCGACGTGCTGATCGTCGCGCGCGGCGGCGGCTCGGTGGAGGACCTGTGGCCCTTCAACGACGAGACCCTCGCGCGCACG
GTCGCCGGCTGCACCATCCCGCTGATCAGCGCGGTGGGCCATGAGACCGACACCACCCTGATCGACTTCGTCTCGGACCG
CCGCGCGCCGACGCCGACCGCCGCCGCCGAGATGGCGACGCCCGTGCTGTCCGAGCTGAAGGCCGCCGTCGGCGACCACG
GCGCGCGCCTGCACCGCTGCGCCGGGCGCGTGGTCGAGGACCGCCGCGGGCGCGTGCAGCACGCGGACCGGGCGCTGAAG
CGCGTCCCCGACCTCGTGGAGCTGGCGGCCCAGCGGTTCGGGATCGTCTCGGGCCGGCTGGCGGCGGGGCTGTCGCGCAA
CGCCGCCGCCCATGAGCGCGACCTGGTGCGAGTGGCTTCGCGCCTGTCGCCGCTGCTGCTCCAGCGGCCGCAGGCGGTGC
AGCGCGAGCGGCTCGAGGCCCTGTCGGTGCGGCTGAAGCCCTGCATGGACCGGCGGCTGGAGCGGCTGTCCGAACGGCTG
GACGCGCTCGCCAAGCTGTACGCCAGCGTCGATCCCGACCGGCCGCTGCAGCGCGGCTTCGCGCGGGTGACCCGCGCGGA
CGGCTCGATCGTCCATGCCGGCGCCTCGCTCGCCAGCGGCGAGGAGGTGGCGATCAAGTTCGGAGACGCGGTGACCCGGC
AGGCGGTGATCGACGGCGCCGACGGCGCGCCGCCGGCGCCCCCGACGCCCGCGGCGGCGAAGAAGCCGAAAATGACGCCG
CCCCTGCAGGGCGACCTGTTCTGA

Upstream 100 bases:

>100_bases
CGTTGGGGATGGGGGGCGCGTCCGGCGCCGGGGCGGCCTCCGCCTCCGGCGCCGGACGCGCCCCTTTCCCATTCCGCCCC
CGGCTCGCTACCTTCCGACG

Downstream 100 bases:

>100_bases
GGCCCGAAGGCGGACTAAATAGGCGGCCATGAACGCCCACGACAGCGACTTCGCCGGCGCCGAGATCGCCAAGCTGCACT
ACGGGGACGGCGACTTCGCC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSEAHATTDAAGPTDGNARPYSVSELAFALKRTLEDAYGFVRLRGELSKVTHHSNGHVYLTLKDDKAAIDGVVWKGQVRN
LSIRPEQGMEVVVTGKITAYPQGSRYQIVIETMEAAGVGALLAQLERLKARLAGEGLFAAERKKPLPTMPSVVGVITSPT
GAVIRDILHRIRDRWPCHVVVWPVVVQGDAAAGQVCAAIRGFCALDPAGPVPRPDVLIVARGGGSVEDLWPFNDETLART
VAGCTIPLISAVGHETDTTLIDFVSDRRAPTPTAAAEMATPVLSELKAAVGDHGARLHRCAGRVVEDRRGRVQHADRALK
RVPDLVELAAQRFGIVSGRLAAGLSRNAAAHERDLVRVASRLSPLLLQRPQAVQRERLEALSVRLKPCMDRRLERLSERL
DALAKLYASVDPDRPLQRGFARVTRADGSIVHAGASLASGEEVAIKFGDAVTRQAVIDGADGAPPAPPTPAAAKKPKMTP
PLQGDLF

Sequences:

>Translated_487_residues
MSEAHATTDAAGPTDGNARPYSVSELAFALKRTLEDAYGFVRLRGELSKVTHHSNGHVYLTLKDDKAAIDGVVWKGQVRN
LSIRPEQGMEVVVTGKITAYPQGSRYQIVIETMEAAGVGALLAQLERLKARLAGEGLFAAERKKPLPTMPSVVGVITSPT
GAVIRDILHRIRDRWPCHVVVWPVVVQGDAAAGQVCAAIRGFCALDPAGPVPRPDVLIVARGGGSVEDLWPFNDETLART
VAGCTIPLISAVGHETDTTLIDFVSDRRAPTPTAAAEMATPVLSELKAAVGDHGARLHRCAGRVVEDRRGRVQHADRALK
RVPDLVELAAQRFGIVSGRLAAGLSRNAAAHERDLVRVASRLSPLLLQRPQAVQRERLEALSVRLKPCMDRRLERLSERL
DALAKLYASVDPDRPLQRGFARVTRADGSIVHAGASLASGEEVAIKFGDAVTRQAVIDGADGAPPAPPTPAAAKKPKMTP
PLQGDLF
>Mature_486_residues
SEAHATTDAAGPTDGNARPYSVSELAFALKRTLEDAYGFVRLRGELSKVTHHSNGHVYLTLKDDKAAIDGVVWKGQVRNL
SIRPEQGMEVVVTGKITAYPQGSRYQIVIETMEAAGVGALLAQLERLKARLAGEGLFAAERKKPLPTMPSVVGVITSPTG
AVIRDILHRIRDRWPCHVVVWPVVVQGDAAAGQVCAAIRGFCALDPAGPVPRPDVLIVARGGGSVEDLWPFNDETLARTV
AGCTIPLISAVGHETDTTLIDFVSDRRAPTPTAAAEMATPVLSELKAAVGDHGARLHRCAGRVVEDRRGRVQHADRALKR
VPDLVELAAQRFGIVSGRLAAGLSRNAAAHERDLVRVASRLSPLLLQRPQAVQRERLEALSVRLKPCMDRRLERLSERLD
ALAKLYASVDPDRPLQRGFARVTRADGSIVHAGASLASGEEVAIKFGDAVTRQAVIDGADGAPPAPPTPAAAKKPKMTPP
LQGDLF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=435, Percent_Identity=36.7816091954023, Blast_Score=254, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 52125; Mature: 51994

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAHATTDAAGPTDGNARPYSVSELAFALKRTLEDAYGFVRLRGELSKVTHHSNGHVYL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEHHHHHHHEECCCCEEEE
TLKDDKAAIDGVVWKGQVRNLSIRPEQGMEVVVTGKITAYPQGSRYQIVIETMEAAGVGA
EECCCCHHHCCEEEECCCCCEEECCCCCCEEEEEEEEEECCCCCEEEEEEEEHHHCCHHH
LLAQLERLKARLAGEGLFAAERKKPLPTMPSVVGVITSPTGAVIRDILHRIRDRWPCHVV
HHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHEECCCHHHHHHHHHHHHHCCCCCEEE
VWPVVVQGDAAAGQVCAAIRGFCALDPAGPVPRPDVLIVARGGGSVEDLWPFNDETLART
EEEEEEECCCHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
VAGCTIPLISAVGHETDTTLIDFVSDRRAPTPTAAAEMATPVLSELKAAVGDHGARLHRC
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AGRVVEDRRGRVQHADRALKRVPDLVELAAQRFGIVSGRLAAGLSRNAAAHERDLVRVAS
HHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHH
RLSPLLLQRPQAVQRERLEALSVRLKPCMDRRLERLSERLDALAKLYASVDPDRPLQRGF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ARVTRADGSIVHAGASLASGEEVAIKFGDAVTRQAVIDGADGAPPAPPTPAAAKKPKMTP
HHHHHCCCCEEECCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
PLQGDLF
CCCCCCC
>Mature Secondary Structure 
SEAHATTDAAGPTDGNARPYSVSELAFALKRTLEDAYGFVRLRGELSKVTHHSNGHVYL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEHHHHHHHEECCCCEEEE
TLKDDKAAIDGVVWKGQVRNLSIRPEQGMEVVVTGKITAYPQGSRYQIVIETMEAAGVGA
EECCCCHHHCCEEEECCCCCEEECCCCCCEEEEEEEEEECCCCCEEEEEEEEHHHCCHHH
LLAQLERLKARLAGEGLFAAERKKPLPTMPSVVGVITSPTGAVIRDILHRIRDRWPCHVV
HHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHEECCCHHHHHHHHHHHHHCCCCCEEE
VWPVVVQGDAAAGQVCAAIRGFCALDPAGPVPRPDVLIVARGGGSVEDLWPFNDETLART
EEEEEEECCCHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
VAGCTIPLISAVGHETDTTLIDFVSDRRAPTPTAAAEMATPVLSELKAAVGDHGARLHRC
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AGRVVEDRRGRVQHADRALKRVPDLVELAAQRFGIVSGRLAAGLSRNAAAHERDLVRVAS
HHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHH
RLSPLLLQRPQAVQRERLEALSVRLKPCMDRRLERLSERLDALAKLYASVDPDRPLQRGF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ARVTRADGSIVHAGASLASGEEVAIKFGDAVTRQAVIDGADGAPPAPPTPAAAKKPKMTP
HHHHHCCCCEEECCCCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
PLQGDLF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA