Click here to switch to the map view.

The map label for this gene is napA [H]

Identifier: 197106362

GI number: 197106362

Start: 3315466

End: 3316785

Strand: Direct

Name: napA [H]

Synonym: PHZ_c2901

Alternate gene names: 197106362

Gene position: 3315466-3316785 (Clockwise)

Preceding gene: 197106361

Following gene: 197106364

Centisome position: 82.96

GC content: 76.44

Gene sequence:

>1320_bases
ATGGCGCCGGCGGAACTGAGCGTCGTCTTCTTCGCCGGGCTGGCGGTGATCGTGGCCACGGCCCGGCTCGTCGGCTGGCT
GGGCCGGCGCTTCCTGGGCCAGCCGCAGGTGATGGGCGAGATGGTCGCCGGCGTCCTGCTGGGTCCCTCTCTGCTCGGCC
TGCTGGCGCCCGGCGTGCAGGCGGCGCTGTTCCCGGACGAGGCCCGCGACAGCCTCTACGTCTGCGCGCAGCTGGGCGTC
GGTCTCTACATGTTCCTGGTCGGGCTGGACTTCGACCGCGACCGCTTCGGGGCCCACGCGGCGAGCGCGGGCGCGGTGGC
CCTCGCGGGCCTGGCCGTCCCCTTTGCGGCCGCCGCGGCCCTGACGCCCTGGCTGATGACGACGCCCGGCTTGTTCGCCC
CGCAACTGGGCGGGCTTCAGGCGACGCTGTTCCTGGGCGCCTGCATCTCGATCACCGCCTTCCCGATGCTGGCCCGGATC
GTCGAGGAGCGGGGCCTGTCGGGCTCGCCGCTCGGAACGCTCACGCTCTCGGCGGGGGCGATGAGCGACGCCTTCGCCTG
GGCGGTCCTGGCGCTGGTGCTGGCCGGCGCGGGCGCCGGCTCGGCGGTGAAGGCGCTGGCCGGCGGGGCGGCCTTCGCGG
CCCTGGTCCTGGGGCTGGGGCCCCGGCTGCTGCGGCCCCTGGGCCGCGCCGCCGAGCGGGGCGGCGGCGTGGACGCGGGC
CTCCTGTCGACGGCGCTGGCGCTGTTCCTGCTGGCCGCCGCCGCGGCGGACTGGCTGGGCCTCCACGCGGTGTTCGGCGG
CTTCGTGCTCGGCGTGGCGATGCCGCGCGGGGTCCTGGCGCGCGAGCTCCGCGCCCGGCTGGAGCCGTTCACCGTGGCCC
TGCTGGCGCCCCTGTTCTTCGCCTACTCGGGGCTGAGCACCCGGCTGGACCTGATCGCCGACCCGGGCCTGCTGGCCGCG
GGCGCGGCGATCCTGGCGGCCTCGATCCTGGCCAAGGGCGGGGCCTGCTGGGCCGCGGCGCGGCTGACGGGCCAGGACAA
CCCCGCCGCCCTCGCCATCGGCGCGCTGATGAACGCCCGCGGCATGATGGAGCTGATCGTCATCAACATCGGCCTGCAGC
GGGGCCTGATCGGACCGGGCCTGTTCTCGGTGCTGGTGCTGATGACCTTGGTCACGACCCTGATGGCCGCGCCGGTGCTC
GAGGCGGCGTACGGCCGCCGCGCGCGAGCCCGGGGCGAGTTGGGAAGGCTGCGCGATCCGGCGGCAGGGACGCCCCCGGC
CGGGGCCGACGCTCAGACGGGCGCGACCGCCCGGCGGTAG

Upstream 100 bases:

>100_bases
TAGGGATGCGGGCCCCGTTTCGCCCGTCCGGCGACGCCGCCGCTTCACACGCCCCGCCCCTCATGGTAGCGATAACATCG
TTGTCCGGACGGGGGCGTGC

Downstream 100 bases:

>100_bases
AGCCGCCAGCTCGCGTGGCCGAGGACGGGCAGGACCACGATCAGCCCGAGCAGCGCCGGCAGCGAGCCCAGGACCAGCAG
GCCGGCGACGATCAGGCCCC

Product: Kef-type K+ transport system, membrane component

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MAPAELSVVFFAGLAVIVATARLVGWLGRRFLGQPQVMGEMVAGVLLGPSLLGLLAPGVQAALFPDEARDSLYVCAQLGV
GLYMFLVGLDFDRDRFGAHAASAGAVALAGLAVPFAAAAALTPWLMTTPGLFAPQLGGLQATLFLGACISITAFPMLARI
VEERGLSGSPLGTLTLSAGAMSDAFAWAVLALVLAGAGAGSAVKALAGGAAFAALVLGLGPRLLRPLGRAAERGGGVDAG
LLSTALALFLLAAAAADWLGLHAVFGGFVLGVAMPRGVLARELRARLEPFTVALLAPLFFAYSGLSTRLDLIADPGLLAA
GAAILAASILAKGGACWAAARLTGQDNPAALAIGALMNARGMMELIVINIGLQRGLIGPGLFSVLVLMTLVTTLMAAPVL
EAAYGRRARARGELGRLRDPAAGTPPAGADAQTGATARR

Sequences:

>Translated_439_residues
MAPAELSVVFFAGLAVIVATARLVGWLGRRFLGQPQVMGEMVAGVLLGPSLLGLLAPGVQAALFPDEARDSLYVCAQLGV
GLYMFLVGLDFDRDRFGAHAASAGAVALAGLAVPFAAAAALTPWLMTTPGLFAPQLGGLQATLFLGACISITAFPMLARI
VEERGLSGSPLGTLTLSAGAMSDAFAWAVLALVLAGAGAGSAVKALAGGAAFAALVLGLGPRLLRPLGRAAERGGGVDAG
LLSTALALFLLAAAAADWLGLHAVFGGFVLGVAMPRGVLARELRARLEPFTVALLAPLFFAYSGLSTRLDLIADPGLLAA
GAAILAASILAKGGACWAAARLTGQDNPAALAIGALMNARGMMELIVINIGLQRGLIGPGLFSVLVLMTLVTTLMAAPVL
EAAYGRRARARGELGRLRDPAAGTPPAGADAQTGATARR
>Mature_438_residues
APAELSVVFFAGLAVIVATARLVGWLGRRFLGQPQVMGEMVAGVLLGPSLLGLLAPGVQAALFPDEARDSLYVCAQLGVG
LYMFLVGLDFDRDRFGAHAASAGAVALAGLAVPFAAAAALTPWLMTTPGLFAPQLGGLQATLFLGACISITAFPMLARIV
EERGLSGSPLGTLTLSAGAMSDAFAWAVLALVLAGAGAGSAVKALAGGAAFAALVLGLGPRLLRPLGRAAERGGGVDAGL
LSTALALFLLAAAAADWLGLHAVFGGFVLGVAMPRGVLARELRARLEPFTVALLAPLFFAYSGLSTRLDLIADPGLLAAG
AAILAASILAKGGACWAAARLTGQDNPAALAIGALMNARGMMELIVINIGLQRGLIGPGLFSVLVLMTLVTTLMAAPVLE
AAYGRRARARGELGRLRDPAAGTPPAGADAQTGATARR

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=390, Percent_Identity=31.025641025641, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 44201; Mature: 44070

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPAELSVVFFAGLAVIVATARLVGWLGRRFLGQPQVMGEMVAGVLLGPSLLGLLAPGVQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AALFPDEARDSLYVCAQLGVGLYMFLVGLDFDRDRFGAHAASAGAVALAGLAVPFAAAAA
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCHHHHHHHHHHHHHHHHH
LTPWLMTTPGLFAPQLGGLQATLFLGACISITAFPMLARIVEERGLSGSPLGTLTLSAGA
HCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
MSDAFAWAVLALVLAGAGAGSAVKALAGGAAFAALVLGLGPRLLRPLGRAAERGGGVDAG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHH
LLSTALALFLLAAAAADWLGLHAVFGGFVLGVAMPRGVLARELRARLEPFTVALLAPLFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHH
AYSGLSTRLDLIADPGLLAAGAAILAASILAKGGACWAAARLTGQDNPAALAIGALMNAR
HHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHHHHHHHC
GMMELIVINIGLQRGLIGPGLFSVLVLMTLVTTLMAAPVLEAAYGRRARARGELGRLRDP
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHCCCCC
AAGTPPAGADAQTGATARR
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
APAELSVVFFAGLAVIVATARLVGWLGRRFLGQPQVMGEMVAGVLLGPSLLGLLAPGVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
AALFPDEARDSLYVCAQLGVGLYMFLVGLDFDRDRFGAHAASAGAVALAGLAVPFAAAAA
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCHHHHHHHHHHHHHHHHH
LTPWLMTTPGLFAPQLGGLQATLFLGACISITAFPMLARIVEERGLSGSPLGTLTLSAGA
HCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
MSDAFAWAVLALVLAGAGAGSAVKALAGGAAFAALVLGLGPRLLRPLGRAAERGGGVDAG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHH
LLSTALALFLLAAAAADWLGLHAVFGGFVLGVAMPRGVLARELRARLEPFTVALLAPLFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHH
AYSGLSTRLDLIADPGLLAAGAAILAASILAKGGACWAAARLTGQDNPAALAIGALMNAR
HHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHHHHHHHC
GMMELIVINIGLQRGLIGPGLFSVLVLMTLVTTLMAAPVLEAAYGRRARARGELGRLRDP
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHCCCCC
AAGTPPAGADAQTGATARR
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]