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The map label for this gene is lhr [C]

Identifier: 197106222

GI number: 197106222

Start: 3166714

End: 3169215

Strand: Direct

Name: lhr [C]

Synonym: PHZ_c2761

Alternate gene names: 197106222

Gene position: 3166714-3169215 (Clockwise)

Preceding gene: 197106218

Following gene: 197106223

Centisome position: 79.24

GC content: 71.38

Gene sequence:

>2502_bases
ATGGCCGACGCCGCCGACCCCGCCCTGCCCTCGGGCCTGCTGCCGCCAAGGTTCCAGGCCTGGTTCGAGGCGCGCGGCTG
GCGCCCCCGACCCCACCAGCTCGAGATGGTGGAGAAGGGCCGGCAGGGCCGCCACGCGCTGCTGATCGCCCCCACCGGCG
GCGGCAAGACCCTGGCCGGGTTCCTCCCCAGCCTGATCGAGCTCGCCGAGCGGCCGCCGGCGAACACCCCGCGCGGCCTG
CACACCCTCTACATCTCGCCGCTGAAGGCCCTGGCGGTGGACGTGGAGCGGAACCTCAACGCCCCGATCCTGCAGATGGG
TCTGCCGGTCGTCGCCGAGAGCCGGACGGGCGACACCGGGGTCGCGCGCCGCCAGCGCCAGCGCGTCAAGCCGCCCGACA
TCCTGCTGACCACGCCGGAGCAGCTGGCCCTGCTCTGCGCCTGGGAGGGCGCGCGACTGTTCTTCGAGGACCTGCGCTGC
GTGATCCTCGACGAGATCCACACCCTGCATTCGTCCAAGCGCGGCGACCTCCTGGCCCTGGACCTCGCCCGCCTGCAGCA
GCTCGCCCCGAACATGCGCCGCGTGGGGCTGAGCGCGACGGTGGACGATCCGGAGGTGATCAAGGCGTGGATGGGGGTGC
ATGCGGCGGACGTCGTCAGTCCTCCTCCCGTTGCTACAGAGAGGGGCGTCGACCTCGTGCTCGGTCCGGCGGGAGCCGAG
CCGGTGGTGGACATCCTGCTGTCCGAGGGGCGGGTCCCGTGGGCCGGCCACACGGCCCAGCACGCCATGGCCGAGGTCTA
CGACGCCATCCGCAAGGCGCGCACGGCGCTGGTGTTCGTCAACACCCGCTTCCAGGCGGAGTTCGCGTTCCAGGAGCTGT
GGCGGCTGAACGACGACGCCCTGCCGATCGCCCTGCACCACGGGAGCCTGGCGGCCGAGCAGCGGCGCAAGGTCGAGGCG
GCGATGGCGCGCGGCGAACTGCGGGCCGTGGTCTGCACCTCCACCCTCGACCTCGGCATCGACTGGGGGGACGTCGACCT
CGTCATCCAGCTCGCCAGCCCCAAGGGCGCCTCGCGGATGGTCCAGCGGATCGGCCGGGCCAACCACCGGCTGGACGAGC
CCTCGCGGGCGCTGTTCGTGCCCGCGAACCGGTTCGAGATGCTGGAGTGCCAGGCCGCCCGCGAGGCGATCGCAGAGAAC
CGGCTGGACGGCGACCCGCCGCGGGTCGGCGCGCTGGACGTGCTGGCCCAGCACGTCATGGGCTGCGCCTGTTCCGAGCC
GTTCGACATGCTGGCGCTCTACGACGAGGTGCGCACGGCCGGCCCCTACCGGGACCTGTCCTGGGAGGACTTCGAGCAGG
TCGTGGATTTCGTCTCCACCGGCGGCTACGCCCTGAAGACCTACGACCGCTTCCGGCGGATCGTGCAGGGGCCGGACGGC
CGCTGGCGGGTCCGCAACGCCCAGATCGCCCAGCGGCACCGGCTGAACGTCGGGGCGATCGTCTCGCCGGCCATGCTGTC
GGTGCGCATCGCCGGGCGGGGCGGCCGTGGCGGGCGCAAGATCGGCGAGATCGAGGAAGGCATGCTCGAGATGCTGGACC
CGGGCGACACCTTCGTGTTCGCCGGCCAGGTCTGGGCGCTGGAGGCGGTGACCAACCTCGACGTCCTGGTGCGCCCGGCG
GGCGACAAGGACCCGAAGATGCCCTCGTGGGGCGGCTCGAAGTTCGCGCTGTCGACCTACCTCGCCAAGCGCGTGCGCCA
GCTGATGTTCGACGAGAGCCACTGGGGCGTCCTGCCGCTCGACACCCGTGAGTGGCTGGAGGCCCAGCGCGACCGCTCGA
TGATCGTCGGCGAGGACGAGATGCTGCTCGAGACCTTCCCGCACGGGAAGCGGCATTTCCTCGTCTGCTACCCCTTCGAC
GGTCGCCTGGCGCACACCACCCTGGCCATGCTGCTGACGCGGCGCCTGGAGCGGGCCGGCGTCGGGCCCCTGGGCTTCGT
CTGCAACGACTATGCGATGGCGGTCTGGGCGCTGAACCCGATGGACGGTCTCGACTTCGACGAGCTGTTCGCGCAGGACA
TGCTGGGCGACGACCTGGAGGCGTGGCTCGCCGAGAGCTTCATGATGAAGCGCGCCTTCAAGGGCTGTGCGATCATCGCG
GGCCTGATCGAGCGGCGCTTCCCCGGCGAGCAGCAGAAGACCGGGCGGCAGATCACCTTCTCCACCGACCTGATCTACGA
CGTGCTCAGGCGCCACGAGCCGGATCACCTGCTGCTGCGCTGCGCCCGAGCGGATGCGGCGACCGGCCTCATCGACGTGG
CGCGGCTGGCGCAGATGCTGGCGCGCATCCGCGGCCGCATCCGGCACGCGCCTCTCGACCACCTCTCGCCCTTCTCGGTC
CCCATCCTGCTGGAGATCGGCAAGGAGCGCTCGCCGGGCGGAGCCTCGGACCTGATGCTGGCGGAAGCCGAAGCCGAACT
GATATCGGAAGCCCTGTCGTGA

Upstream 100 bases:

>100_bases
AGCCAGTTCTAGCCTCAAGAACTTAGGATCGCGCGCGCCTTTTGCCACGCTCATCGACGGGGCTGCCGAAACGAACCGCG
AACATGCTATAGGGCCCGCG

Downstream 100 bases:

>100_bases
ACGCCCTTGCGCCCCTCTTCGCCTACGCCTTCGCCGCCAGCGGCTGCGGGGGCCTGCGGACCCATGTGGCGGGGACCGAA
GTCGTGATGCGCGCCTCGGG

Product: ATP-dependent RNA helicase, DEAD/DEAH family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 833; Mature: 832

Protein sequence:

>833_residues
MADAADPALPSGLLPPRFQAWFEARGWRPRPHQLEMVEKGRQGRHALLIAPTGGGKTLAGFLPSLIELAERPPANTPRGL
HTLYISPLKALAVDVERNLNAPILQMGLPVVAESRTGDTGVARRQRQRVKPPDILLTTPEQLALLCAWEGARLFFEDLRC
VILDEIHTLHSSKRGDLLALDLARLQQLAPNMRRVGLSATVDDPEVIKAWMGVHAADVVSPPPVATERGVDLVLGPAGAE
PVVDILLSEGRVPWAGHTAQHAMAEVYDAIRKARTALVFVNTRFQAEFAFQELWRLNDDALPIALHHGSLAAEQRRKVEA
AMARGELRAVVCTSTLDLGIDWGDVDLVIQLASPKGASRMVQRIGRANHRLDEPSRALFVPANRFEMLECQAAREAIAEN
RLDGDPPRVGALDVLAQHVMGCACSEPFDMLALYDEVRTAGPYRDLSWEDFEQVVDFVSTGGYALKTYDRFRRIVQGPDG
RWRVRNAQIAQRHRLNVGAIVSPAMLSVRIAGRGGRGGRKIGEIEEGMLEMLDPGDTFVFAGQVWALEAVTNLDVLVRPA
GDKDPKMPSWGGSKFALSTYLAKRVRQLMFDESHWGVLPLDTREWLEAQRDRSMIVGEDEMLLETFPHGKRHFLVCYPFD
GRLAHTTLAMLLTRRLERAGVGPLGFVCNDYAMAVWALNPMDGLDFDELFAQDMLGDDLEAWLAESFMMKRAFKGCAIIA
GLIERRFPGEQQKTGRQITFSTDLIYDVLRRHEPDHLLLRCARADAATGLIDVARLAQMLARIRGRIRHAPLDHLSPFSV
PILLEIGKERSPGGASDLMLAEAEAELISEALS

Sequences:

>Translated_833_residues
MADAADPALPSGLLPPRFQAWFEARGWRPRPHQLEMVEKGRQGRHALLIAPTGGGKTLAGFLPSLIELAERPPANTPRGL
HTLYISPLKALAVDVERNLNAPILQMGLPVVAESRTGDTGVARRQRQRVKPPDILLTTPEQLALLCAWEGARLFFEDLRC
VILDEIHTLHSSKRGDLLALDLARLQQLAPNMRRVGLSATVDDPEVIKAWMGVHAADVVSPPPVATERGVDLVLGPAGAE
PVVDILLSEGRVPWAGHTAQHAMAEVYDAIRKARTALVFVNTRFQAEFAFQELWRLNDDALPIALHHGSLAAEQRRKVEA
AMARGELRAVVCTSTLDLGIDWGDVDLVIQLASPKGASRMVQRIGRANHRLDEPSRALFVPANRFEMLECQAAREAIAEN
RLDGDPPRVGALDVLAQHVMGCACSEPFDMLALYDEVRTAGPYRDLSWEDFEQVVDFVSTGGYALKTYDRFRRIVQGPDG
RWRVRNAQIAQRHRLNVGAIVSPAMLSVRIAGRGGRGGRKIGEIEEGMLEMLDPGDTFVFAGQVWALEAVTNLDVLVRPA
GDKDPKMPSWGGSKFALSTYLAKRVRQLMFDESHWGVLPLDTREWLEAQRDRSMIVGEDEMLLETFPHGKRHFLVCYPFD
GRLAHTTLAMLLTRRLERAGVGPLGFVCNDYAMAVWALNPMDGLDFDELFAQDMLGDDLEAWLAESFMMKRAFKGCAIIA
GLIERRFPGEQQKTGRQITFSTDLIYDVLRRHEPDHLLLRCARADAATGLIDVARLAQMLARIRGRIRHAPLDHLSPFSV
PILLEIGKERSPGGASDLMLAEAEAELISEALS
>Mature_832_residues
ADAADPALPSGLLPPRFQAWFEARGWRPRPHQLEMVEKGRQGRHALLIAPTGGGKTLAGFLPSLIELAERPPANTPRGLH
TLYISPLKALAVDVERNLNAPILQMGLPVVAESRTGDTGVARRQRQRVKPPDILLTTPEQLALLCAWEGARLFFEDLRCV
ILDEIHTLHSSKRGDLLALDLARLQQLAPNMRRVGLSATVDDPEVIKAWMGVHAADVVSPPPVATERGVDLVLGPAGAEP
VVDILLSEGRVPWAGHTAQHAMAEVYDAIRKARTALVFVNTRFQAEFAFQELWRLNDDALPIALHHGSLAAEQRRKVEAA
MARGELRAVVCTSTLDLGIDWGDVDLVIQLASPKGASRMVQRIGRANHRLDEPSRALFVPANRFEMLECQAAREAIAENR
LDGDPPRVGALDVLAQHVMGCACSEPFDMLALYDEVRTAGPYRDLSWEDFEQVVDFVSTGGYALKTYDRFRRIVQGPDGR
WRVRNAQIAQRHRLNVGAIVSPAMLSVRIAGRGGRGGRKIGEIEEGMLEMLDPGDTFVFAGQVWALEAVTNLDVLVRPAG
DKDPKMPSWGGSKFALSTYLAKRVRQLMFDESHWGVLPLDTREWLEAQRDRSMIVGEDEMLLETFPHGKRHFLVCYPFDG
RLAHTTLAMLLTRRLERAGVGPLGFVCNDYAMAVWALNPMDGLDFDELFAQDMLGDDLEAWLAESFMMKRAFKGCAIIAG
LIERRFPGEQQKTGRQITFSTDLIYDVLRRHEPDHLLLRCARADAATGLIDVARLAQMLARIRGRIRHAPLDHLSPFSVP
ILLEIGKERSPGGASDLMLAEAEAELISEALS

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI38569503, Length=355, Percent_Identity=26.1971830985915, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI38569505, Length=349, Percent_Identity=26.3610315186246, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1787942, Length=917, Percent_Identity=28.7895310796074, Blast_Score=266, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17537127, Length=370, Percent_Identity=25.4054054054054, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI9755332, Length=397, Percent_Identity=24.9370277078086, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320497, Length=364, Percent_Identity=25.8241758241758, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28574898, Length=407, Percent_Identity=24.8157248157248, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 92206; Mature: 92075

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAADPALPSGLLPPRFQAWFEARGWRPRPHQLEMVEKGRQGRHALLIAPTGGGKTLAG
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCHHHH
FLPSLIELAERPPANTPRGLHTLYISPLKALAVDVERNLNAPILQMGLPVVAESRTGDTG
HHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHCCCEEECCCCCCHH
VARRQRQRVKPPDILLTTPEQLALLCAWEGARLFFEDLRCVILDEIHTLHSSKRGDLLAL
HHHHHHHCCCCCCEEEECHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEH
DLARLQQLAPNMRRVGLSATVDDPEVIKAWMGVHAADVVSPPPVATERGVDLVLGPAGAE
HHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHCCHHHHCCCCCCCCCCCCCEEEECCCCCH
PVVDILLSEGRVPWAGHTAQHAMAEVYDAIRKARTALVFVNTRFQAEFAFQELWRLNDDA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHCCCCC
LPIALHHGSLAAEQRRKVEAAMARGELRAVVCTSTLDLGIDWGDVDLVIQLASPKGASRM
EEEEEECCCHHHHHHHHHHHHHHHCCEEEEEEECHHCCCCCCCCEEEEEEECCCCCHHHH
VQRIGRANHRLDEPSRALFVPANRFEMLECQAAREAIAENRLDGDPPRVGALDVLAQHVM
HHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
GCACSEPFDMLALYDEVRTAGPYRDLSWEDFEQVVDFVSTGGYALKTYDRFRRIVQGPDG
HHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCC
RWRVRNAQIAQRHRLNVGAIVSPAMLSVRIAGRGGRGGRKIGEIEEGMLEMLDPGDTFVF
CEEECCHHHHHHHCCCCCCEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEE
AGQVWALEAVTNLDVLVRPAGDKDPKMPSWGGSKFALSTYLAKRVRQLMFDESHWGVLPL
ECCEEEEHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECC
DTREWLEAQRDRSMIVGEDEMLLETFPHGKRHFLVCYPFDGRLAHTTLAMLLTRRLERAG
CHHHHHHHHHCCCEEECCHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
VGPLGFVCNDYAMAVWALNPMDGLDFDELFAQDMLGDDLEAWLAESFMMKRAFKGCAIIA
CCCHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GLIERRFPGEQQKTGRQITFSTDLIYDVLRRHEPDHLLLRCARADAATGLIDVARLAQML
HHHHHCCCCCHHHCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARIRGRIRHAPLDHLSPFSVPILLEIGKERSPGGASDLMLAEAEAELISEALS
HHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHEEHHHHHHHHHHHCC
>Mature Secondary Structure 
ADAADPALPSGLLPPRFQAWFEARGWRPRPHQLEMVEKGRQGRHALLIAPTGGGKTLAG
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCHHHH
FLPSLIELAERPPANTPRGLHTLYISPLKALAVDVERNLNAPILQMGLPVVAESRTGDTG
HHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHCCCEEECCCCCCHH
VARRQRQRVKPPDILLTTPEQLALLCAWEGARLFFEDLRCVILDEIHTLHSSKRGDLLAL
HHHHHHHCCCCCCEEEECHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEH
DLARLQQLAPNMRRVGLSATVDDPEVIKAWMGVHAADVVSPPPVATERGVDLVLGPAGAE
HHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHCCHHHHCCCCCCCCCCCCCEEEECCCCCH
PVVDILLSEGRVPWAGHTAQHAMAEVYDAIRKARTALVFVNTRFQAEFAFQELWRLNDDA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHCCCCC
LPIALHHGSLAAEQRRKVEAAMARGELRAVVCTSTLDLGIDWGDVDLVIQLASPKGASRM
EEEEEECCCHHHHHHHHHHHHHHHCCEEEEEEECHHCCCCCCCCEEEEEEECCCCCHHHH
VQRIGRANHRLDEPSRALFVPANRFEMLECQAAREAIAENRLDGDPPRVGALDVLAQHVM
HHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
GCACSEPFDMLALYDEVRTAGPYRDLSWEDFEQVVDFVSTGGYALKTYDRFRRIVQGPDG
HHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCC
RWRVRNAQIAQRHRLNVGAIVSPAMLSVRIAGRGGRGGRKIGEIEEGMLEMLDPGDTFVF
CEEECCHHHHHHHCCCCCCEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEE
AGQVWALEAVTNLDVLVRPAGDKDPKMPSWGGSKFALSTYLAKRVRQLMFDESHWGVLPL
ECCEEEEHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECC
DTREWLEAQRDRSMIVGEDEMLLETFPHGKRHFLVCYPFDGRLAHTTLAMLLTRRLERAG
CHHHHHHHHHCCCEEECCHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCC
VGPLGFVCNDYAMAVWALNPMDGLDFDELFAQDMLGDDLEAWLAESFMMKRAFKGCAIIA
CCCHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GLIERRFPGEQQKTGRQITFSTDLIYDVLRRHEPDHLLLRCARADAATGLIDVARLAQML
HHHHHCCCCCHHHCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ARIRGRIRHAPLDHLSPFSVPILLEIGKERSPGGASDLMLAEAEAELISEALS
HHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]