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The map label for this gene is pleC [H]

Identifier: 197106174

GI number: 197106174

Start: 3109065

End: 3109838

Strand: Direct

Name: pleC [H]

Synonym: PHZ_c2713

Alternate gene names: 197106174

Gene position: 3109065-3109838 (Clockwise)

Preceding gene: 197106172

Following gene: 197106175

Centisome position: 77.8

GC content: 70.03

Gene sequence:

>774_bases
ATGCCCCCAGCGGCCCCTCTCCGACACACGTCCGCAGACTCGAAGGCCGCCCAGACGGCGCCCGACCGCCGCGCAGCCGC
GACCGACGCCCAGAAGCGCTCGTTCCTGCGGATGGTCAGCCACGAACTGCGCACGCCGCTCAATTCGATCCTCGGCTTCT
CTGAGATTCTCACTTCAGAACTCTACGGCCCCTTGGGGGCTCCGCAGTACAAGGAATATGCCGGGATCATCCGCGAGAGC
GGGCAGAAACTCCTGAAACTTGTGAATCAGGTGTTGGAAATCGCACGGCTCGAGAACCAGAGCGTCGATTTCGATCCTCG
TCCCGAGCCGCTGGAGGCGGCGCTCGACGACGTCCTGGCCGGCCTCGCCGACGAGATCGAGGCCCGTCACGTGGCCGTCG
AGGTGACCGGAAGGGGCGATCTCCCCGTCGTCACCGCCGACCCGCGGGGCCTGCGGACCGTGCTCCATCACCTACTGCAC
AACGCCGTGGCCTTCTCGCCCGAGGGCGGGACGGTCTGGGTGGGGGCCCAGGCGCTGGCGGGGGGCGTCGAGATCGTGAT
CCGCGACGAGGGCGAGGGGATCGACCCGGCCGAGCTGCCGCGGCTGATGACCCCCTTCGAGCAGGGGGAGAACGCCCTGA
CCCGCCATACCGAGGGCGCGGGGCTGGGGCTGCCGATCGCCGACCTGACCTGCAAGGCCATGGGCGGGCGGCTCACGCTG
GCCTCCAAGCCCGGCAAGGGGCTGACGGCCGGCCTGCGCCTGCCGGCCGCCTGA

Upstream 100 bases:

>100_bases
AGGCCGCTCGCGCAGCGGGCGAATACGCCCCCGGATAAGGAAATCGTAAGCGCGATCGCGGACGCTCGCCCTATCAGACG
CGCAGGCCGAAGGCCTTTCC

Downstream 100 bases:

>100_bases
GAGACGTCGCGAGCAAGGTTGCGGCGCGAGGTTGCAGCGGGGGGCCCCGCCCCTTAAGTGGCCGCCATGTCCGCCATCGA
CGACGCGCTGACCGAGCTCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPPAAPLRHTSADSKAAQTAPDRRAAATDAQKRSFLRMVSHELRTPLNSILGFSEILTSELYGPLGAPQYKEYAGIIRES
GQKLLKLVNQVLEIARLENQSVDFDPRPEPLEAALDDVLAGLADEIEARHVAVEVTGRGDLPVVTADPRGLRTVLHHLLH
NAVAFSPEGGTVWVGAQALAGGVEIVIRDEGEGIDPAELPRLMTPFEQGENALTRHTEGAGLGLPIADLTCKAMGGRLTL
ASKPGKGLTAGLRLPAA

Sequences:

>Translated_257_residues
MPPAAPLRHTSADSKAAQTAPDRRAAATDAQKRSFLRMVSHELRTPLNSILGFSEILTSELYGPLGAPQYKEYAGIIRES
GQKLLKLVNQVLEIARLENQSVDFDPRPEPLEAALDDVLAGLADEIEARHVAVEVTGRGDLPVVTADPRGLRTVLHHLLH
NAVAFSPEGGTVWVGAQALAGGVEIVIRDEGEGIDPAELPRLMTPFEQGENALTRHTEGAGLGLPIADLTCKAMGGRLTL
ASKPGKGLTAGLRLPAA
>Mature_256_residues
PPAAPLRHTSADSKAAQTAPDRRAAATDAQKRSFLRMVSHELRTPLNSILGFSEILTSELYGPLGAPQYKEYAGIIRESG
QKLLKLVNQVLEIARLENQSVDFDPRPEPLEAALDDVLAGLADEIEARHVAVEVTGRGDLPVVTADPRGLRTVLHHLLHN
AVAFSPEGGTVWVGAQALAGGVEIVIRDEGEGIDPAELPRLMTPFEQGENALTRHTEGAGLGLPIADLTCKAMGGRLTLA
SKPGKGLTAGLRLPAA

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=31.9327731092437, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=31.4893617021277, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081816, Length=236, Percent_Identity=33.8983050847458, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082128, Length=240, Percent_Identity=30, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=239, Percent_Identity=28.4518828451883, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=30.3418803418803, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=30, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=32.1739130434783, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=28.448275862069, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=27.3504273504274, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=24.7787610619469, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790861, Length=228, Percent_Identity=30.2631578947368, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 27256; Mature: 27125

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAAPLRHTSADSKAAQTAPDRRAAATDAQKRSFLRMVSHELRTPLNSILGFSEILTSE
CCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGPLGAPQYKEYAGIIRESGQKLLKLVNQVLEIARLENQSVDFDPRPEPLEAALDDVLA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
GLADEIEARHVAVEVTGRGDLPVVTADPRGLRTVLHHLLHNAVAFSPEGGTVWVGAQALA
HHHHHHHHEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHEEECCCCCEEEEEHHHHC
GGVEIVIRDEGEGIDPAELPRLMTPFEQGENALTRHTEGAGLGLPIADLTCKAMGGRLTL
CCEEEEEECCCCCCCHHHHHHHHCCHHHCCHHHHHCCCCCCCCCCHHHHHHHHCCCEEEE
ASKPGKGLTAGLRLPAA
ECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPAAPLRHTSADSKAAQTAPDRRAAATDAQKRSFLRMVSHELRTPLNSILGFSEILTSE
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGPLGAPQYKEYAGIIRESGQKLLKLVNQVLEIARLENQSVDFDPRPEPLEAALDDVLA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
GLADEIEARHVAVEVTGRGDLPVVTADPRGLRTVLHHLLHNAVAFSPEGGTVWVGAQALA
HHHHHHHHEEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHEEECCCCCEEEEEHHHHC
GGVEIVIRDEGEGIDPAELPRLMTPFEQGENALTRHTEGAGLGLPIADLTCKAMGGRLTL
CCEEEEEECCCCCCCHHHHHHHHCCHHHCCHHHHHCCCCCCCCCCHHHHHHHHCCCEEEE
ASKPGKGLTAGLRLPAA
ECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]