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The map label for this gene is efp

Identifier: 197106132

GI number: 197106132

Start: 3061142

End: 3061708

Strand: Direct

Name: efp

Synonym: PHZ_c2671

Alternate gene names: 197106132

Gene position: 3061142-3061708 (Clockwise)

Preceding gene: 197106127

Following gene: 197106133

Centisome position: 76.6

GC content: 66.14

Gene sequence:

>567_bases
TTGAAGGTCTCCGCCAGCTCCCTCCGCAAGGGCAACGTCGTCGACCTCGACGGCAAGCTCTACGTCGTGCTCAGCGCCCA
GAACATCCACCCCGGCAAGGGCACGCCGGTCACCCAGCTCGACATGCGCCGCATCTCCGACGGCGTGAAGGTGTCGGAAC
GCTACCGCACCACCGAGACCGTCGAGCGGGCCACCGTGGACGACCGCGACTACACCTTCCTCTACGAGGACGGCGAAGGG
TTCCACTTCATGAATCCCGAGTCGTACGAGCAGGTCACCGCCTCGGCCGAGATGATCGGCGACGCCAAGTACTACCTGAC
GGACGGCTGCACGGTGAAGCTCTCCACCCACGAGGGCGTGCCGATCGCCATCGAGCTGCCGCGCCTGGCGACCTTCGAGG
TCGTGGACACCGAGCCGACCGTGAAGGGCCAGACGGCCTCCTCGTCGTACAAGCCGGCGGTCCTCTCGAACGGCCTGCGC
ACCATGATCCCGCCGTACATCACCGTCGGCACCAAGATCGTCGTCCTGACCGAGGACGGCTCGTACCAGGAACGCGCCAA
GGACTGA

Upstream 100 bases:

>100_bases
GATTTCGGCGACAGCCGCTATAGGGGCGCGGAAACCAATTGATTAGCGGAATCGTGCAGGTGTTCGCCCGCCGCCTCCGC
AGCATCCTCGAGGACAGAAC

Downstream 100 bases:

>100_bases
TCGGCCTTCGGCGGCCCTCTCCTTCATCCTCTCCCTCTCGCTTCGCGGGGGAGAGGATCGAGGCGAGGGCGAGCGCCGCG
AGGCGCGCCCCCCACCTCTT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKVSASSLRKGNVVDLDGKLYVVLSAQNIHPGKGTPVTQLDMRRISDGVKVSERYRTTETVERATVDDRDYTFLYEDGEG
FHFMNPESYEQVTASAEMIGDAKYYLTDGCTVKLSTHEGVPIAIELPRLATFEVVDTEPTVKGQTASSSYKPAVLSNGLR
TMIPPYITVGTKIVVLTEDGSYQERAKD

Sequences:

>Translated_188_residues
MKVSASSLRKGNVVDLDGKLYVVLSAQNIHPGKGTPVTQLDMRRISDGVKVSERYRTTETVERATVDDRDYTFLYEDGEG
FHFMNPESYEQVTASAEMIGDAKYYLTDGCTVKLSTHEGVPIAIELPRLATFEVVDTEPTVKGQTASSSYKPAVLSNGLR
TMIPPYITVGTKIVVLTEDGSYQERAKD
>Mature_188_residues
MKVSASSLRKGNVVDLDGKLYVVLSAQNIHPGKGTPVTQLDMRRISDGVKVSERYRTTETVERATVDDRDYTFLYEDGEG
FHFMNPESYEQVTASAEMIGDAKYYLTDGCTVKLSTHEGVPIAIELPRLATFEVVDTEPTVKGQTASSSYKPAVLSNGLR
TMIPPYITVGTKIVVLTEDGSYQERAKD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=37.1584699453552, Blast_Score=139, Evalue=8e-35,
Organism=Escherichia coli, GI87082061, Length=186, Percent_Identity=32.7956989247312, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_PHEZH (B4RHN9)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002131509.1
- GeneID:   6792193
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c2671
- HOGENOM:   HBG303311
- OMA:   TENGDYK
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20736; Mature: 20736

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSASSLRKGNVVDLDGKLYVVLSAQNIHPGKGTPVTQLDMRRISDGVKVSERYRTTET
CCCCHHHCCCCCEEEECCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEHHHHCCHHH
VERATVDDRDYTFLYEDGEGFHFMNPESYEQVTASAEMIGDAKYYLTDGCTVKLSTHEGV
HHHCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHCCEEEEEECCEEEEEECCCCC
PIAIELPRLATFEVVDTEPTVKGQTASSSYKPAVLSNGLRTMIPPYITVGTKIVVLTEDG
EEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCHHHCCCEEECCCEEEEEECCC
SYQERAKD
CHHHHCCC
>Mature Secondary Structure
MKVSASSLRKGNVVDLDGKLYVVLSAQNIHPGKGTPVTQLDMRRISDGVKVSERYRTTET
CCCCHHHCCCCCEEEECCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEHHHHCCHHH
VERATVDDRDYTFLYEDGEGFHFMNPESYEQVTASAEMIGDAKYYLTDGCTVKLSTHEGV
HHHCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHCCEEEEEECCEEEEEECCCCC
PIAIELPRLATFEVVDTEPTVKGQTASSSYKPAVLSNGLRTMIPPYITVGTKIVVLTEDG
EEEEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCHHHCCCEEECCCEEEEEECCC
SYQERAKD
CHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA