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The map label for this gene is trxB [H]

Identifier: 197106064

GI number: 197106064

Start: 2991869

End: 2992888

Strand: Direct

Name: trxB [H]

Synonym: PHZ_c2603

Alternate gene names: 197106064

Gene position: 2991869-2992888 (Clockwise)

Preceding gene: 197106060

Following gene: 197106065

Centisome position: 74.87

GC content: 69.12

Gene sequence:

>1020_bases
ATGTCCGAGAACGCTCCCCGCCCCGAACCCCGTTCCGTCCGCTGCCTGATCGTGGGCTCCGGCCCCGCGGGCTACACCGC
CGCCATCTACGCCGCCCGGGCGCTGCTGAAGCCCGTGCTGATCCAGGGCATCCAGCCCGGCGGCCAGCTCACCATCACCA
CCGACGTGGAGAACTATCCGGGCTTCGCCGACGTCATCCAGGGGCCCTGGCTGATGGAGCAGATGCAGGCCCAGGCCGAG
CACGTGGGCACCGAGATCGTCAACGACATCGTCGTGAAGGCCGACCTGTCGCAGCGGCCCTTCCGGCTGGAGACCGACAG
CGGCCAGACCTGGCTCGCCGAGACCCTGATCATCGCCACCGGCGCCCAGGCCAAGTGGCTGGGGCTGGAGTCCGAGCAGA
AGTTCCAGGGCTTCGGCGTCTCGGCCTGCGCCACCTGCGACGGCTTCTTCTATCGCGGCAAGAACGTCGTGGTGGTCGGC
GGCGGCAACACGGCGGTGGAGGAGGCCCTGTTCCTCACCAACTTCGCCGCCAAGGTGACGCTGGTGCATCGCCGCGACGA
GCTGCGCGCCGAACGGATCCTGCAGGAGCGCCTGTTCAACCACGAGAAGATCGAGGTGATCTGGGACAGCGCCATCGACG
AGGTGGTGGGCCAGACCGATCCGCTCGGCGTCACCGGCGTGCGGCTGAAGAACGTCAAGACGGGCGAGACCCGCGAGATC
CCCTGCGACGGCGTGTTCATCGCCATCGGCCATGCGCCCGCCTCCGAGCTGTTCAAGGGCCAGCTCGAGATGGACGCCTC
CGGCTATCTGAAGGTGAAGCCGGGCACGGCCTCGACGGCGATCCAGGGCGTCTACGCGGCGGGCGACGTCACCGACGACG
TCTACCGCCAGGCGGTCACGGCGGCCGGAATGGGCTGCATGGCGGCGCTGGAGGCGGTCCGCTTCCTCGCCGAGGAGGAC
CACCGCAAGGCCCACCATCCGATCAGCCACGGCGAGGCTCAGAAGATCGGGGCCTGGTAG

Upstream 100 bases:

>100_bases
CGCGCCGATCCCCGCGCCGAGGGCGATGCCGATCGCGATCCACAGGGCCATGACATCGCTCCTTGTCGCAACGGGCCAGA
ATCCAACTTACATAGGGGCG

Downstream 100 bases:

>100_bases
CCGCGCAACCGCAAATTGTACGGCCGCGCTGAAACCCGACCCCCTTTTGGCGGGTTGGGCGAGGCCATGCGGAACAGCGA
ACGCTACGCAGAACAGGCCG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSENAPRPEPRSVRCLIVGSGPAGYTAAIYAARALLKPVLIQGIQPGGQLTITTDVENYPGFADVIQGPWLMEQMQAQAE
HVGTEIVNDIVVKADLSQRPFRLETDSGQTWLAETLIIATGAQAKWLGLESEQKFQGFGVSACATCDGFFYRGKNVVVVG
GGNTAVEEALFLTNFAAKVTLVHRRDELRAERILQERLFNHEKIEVIWDSAIDEVVGQTDPLGVTGVRLKNVKTGETREI
PCDGVFIAIGHAPASELFKGQLEMDASGYLKVKPGTASTAIQGVYAAGDVTDDVYRQAVTAAGMGCMAALEAVRFLAEED
HRKAHHPISHGEAQKIGAW

Sequences:

>Translated_339_residues
MSENAPRPEPRSVRCLIVGSGPAGYTAAIYAARALLKPVLIQGIQPGGQLTITTDVENYPGFADVIQGPWLMEQMQAQAE
HVGTEIVNDIVVKADLSQRPFRLETDSGQTWLAETLIIATGAQAKWLGLESEQKFQGFGVSACATCDGFFYRGKNVVVVG
GGNTAVEEALFLTNFAAKVTLVHRRDELRAERILQERLFNHEKIEVIWDSAIDEVVGQTDPLGVTGVRLKNVKTGETREI
PCDGVFIAIGHAPASELFKGQLEMDASGYLKVKPGTASTAIQGVYAAGDVTDDVYRQAVTAAGMGCMAALEAVRFLAEED
HRKAHHPISHGEAQKIGAW
>Mature_338_residues
SENAPRPEPRSVRCLIVGSGPAGYTAAIYAARALLKPVLIQGIQPGGQLTITTDVENYPGFADVIQGPWLMEQMQAQAEH
VGTEIVNDIVVKADLSQRPFRLETDSGQTWLAETLIIATGAQAKWLGLESEQKFQGFGVSACATCDGFFYRGKNVVVVGG
GNTAVEEALFLTNFAAKVTLVHRRDELRAERILQERLFNHEKIEVIWDSAIDEVVGQTDPLGVTGVRLKNVKTGETREIP
CDGVFIAIGHAPASELFKGQLEMDASGYLKVKPGTASTAIQGVYAAGDVTDDVYRQAVTAAGMGCMAALEAVRFLAEEDH
RKAHHPISHGEAQKIGAW

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=314, Percent_Identity=54.4585987261147, Blast_Score=333, Evalue=8e-93,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=32.4590163934426, Blast_Score=142, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=45.3674121405751, Blast_Score=283, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=44.1640378548896, Blast_Score=274, Evalue=2e-74,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 36573; Mature: 36442

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENAPRPEPRSVRCLIVGSGPAGYTAAIYAARALLKPVLIQGIQPGGQLTITTDVENYP
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
GFADVIQGPWLMEQMQAQAEHVGTEIVNDIVVKADLSQRPFRLETDSGQTWLAETLIIAT
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCEEEEEEEEEEC
GAQAKWLGLESEQKFQGFGVSACATCDGFFYRGKNVVVVGGGNTAVEEALFLTNFAAKVT
CCCEEEECCCCCCHHCCCCCHHHHHCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHEEE
LVHRRDELRAERILQERLFNHEKIEVIWDSAIDEVVGQTDPLGVTGVRLKNVKTGETREI
EEECHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCEECEEEECCCCCCCCCC
PCDGVFIAIGHAPASELFKGQLEMDASGYLKVKPGTASTAIQGVYAAGDVTDDVYRQAVT
CCCCEEEEECCCCHHHHHCCCEEECCCCEEEECCCCCHHHHHEEEECCCCCHHHHHHHHH
AAGMGCMAALEAVRFLAEEDHRKAHHPISHGEAQKIGAW
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCC
>Mature Secondary Structure 
SENAPRPEPRSVRCLIVGSGPAGYTAAIYAARALLKPVLIQGIQPGGQLTITTDVENYP
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
GFADVIQGPWLMEQMQAQAEHVGTEIVNDIVVKADLSQRPFRLETDSGQTWLAETLIIAT
CHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCCCCEEEEEEEEEEC
GAQAKWLGLESEQKFQGFGVSACATCDGFFYRGKNVVVVGGGNTAVEEALFLTNFAAKVT
CCCEEEECCCCCCHHCCCCCHHHHHCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHEEE
LVHRRDELRAERILQERLFNHEKIEVIWDSAIDEVVGQTDPLGVTGVRLKNVKTGETREI
EEECHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCEECEEEECCCCCCCCCC
PCDGVFIAIGHAPASELFKGQLEMDASGYLKVKPGTASTAIQGVYAAGDVTDDVYRQAVT
CCCCEEEEECCCCHHHHHCCCEEECCCCEEEECCCCCHHHHHEEEECCCCCHHHHHHHHH
AAGMGCMAALEAVRFLAEEDHRKAHHPISHGEAQKIGAW
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]