Click here to switch to the map view.

The map label for this gene is 197106062

Identifier: 197106062

GI number: 197106062

Start: 2990546

End: 2991604

Strand: Reverse

Name: 197106062

Synonym: PHZ_c2601

Alternate gene names: NA

Gene position: 2991604-2990546 (Counterclockwise)

Preceding gene: 197106063

Following gene: 197106061

Centisome position: 74.86

GC content: 72.05

Gene sequence:

>1059_bases
ATGTCGACTCATCCGCAGGTCGAGATCGCCGGGCGCAAGGTGGGGGCCGGTCACGAGCCGTTCGTGATCTGCGAGCTGTC
GGGCAACCACAACGGCAGCCTGGAGCGGGCGCTGGCGATGATCGACGCGGCGGCGGCGACTGGCTGCGACGCGGTCAAGA
TCCAGACCTACACCGCCGACACCATCACCATGGACGTGGACCGGCCGGAATTCCGGATCCGCGGGGGCCTGTGGGACGGC
CGCAGCCTCTACGAGCTCTACCGCGAGGCCCAGACGCCCTACGAGTGGCACGCGGCGCTGTTCCGGCGGGCGCGCGAGCT
GGGCGTGATCCTGTTCTCCAGCCCGTTCGACGAGACGGCGGTGGACCTGCTCGCCGGGCTGGACGCTCCCGCCTACAAGA
TCGCCTCCTTCGAGGCCGTGGACCTGCCGCTGATCCGCTACGCCGCGTCCAAGGGCAAGCCGCTGATCATCTCGACCGGC
ATGGCCAACCTCGCCGAGATCGAGGCGGCGCGCGATGCGGCGCTGTCGGCGGGCGCGCCGGGGGTGGTGCTGCTGCACTG
CGTCTCCAGCTATCCGGCGCCGCTCGAGGACGCCAACGTCCGCACGGTCGCCGACATGGCGCAGCGCTTCGCCTGTCCGG
TCGGGCTTTCGGACCACACGCCCGGAACGGCGGCCGCAGTCGCGGCCGTGGCCCTGGGCGCCTCGGTGATCGAGAAGCAC
TTCACCCTCGCCCGGGCTGACGGCGGACCCGACGCGGCCTTCAGCCTGGAGCCGGCCGAGTTCGCGGCCCTGGTGCGCGA
CTGCAAGGCCGCCTGGCGGGCCCTGGGCCGGGCCCAGTACGATCTGGTAGGGGCCGAGCGGGGGAACGTGCAGTTCCGTC
GTTCGCTCTACGTGGCGGCCGACGTGAAGGCCGGCGAGCCGTTGACCAGGCTCAATGTGCGCTCGATCCGGCCGGGCGAC
GGTCTGCCTCCGGCTGAGCTGGAGGCGGTGCTGGGCCGCCCCGCGACGCGGGACCTGAGGCGGGGGGAGCCCCTGGCGTG
GGATATGGTGAGCCGATGA

Upstream 100 bases:

>100_bases
CGGGCGGACGCAAGGGCCCGCCGAAGACATGACCCGCCCTTCAAGGGCGGCCCTCGTGCTTAACGCGCCCTTCAGGGCGC
AGGTGGCGTAGAATGGCGCC

Downstream 100 bases:

>100_bases
GCGTCCGGCTGCGCAAGGTCGAGCACGAGGACAGCGCCCGCCTGCTGGAGTGGCGCAACTCGCCCGACGTGTCGGCCTTC
ATGTACACCGACCACCGCAT

Product: N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSTHPQVEIAGRKVGAGHEPFVICELSGNHNGSLERALAMIDAAAATGCDAVKIQTYTADTITMDVDRPEFRIRGGLWDG
RSLYELYREAQTPYEWHAALFRRARELGVILFSSPFDETAVDLLAGLDAPAYKIASFEAVDLPLIRYAASKGKPLIISTG
MANLAEIEAARDAALSAGAPGVVLLHCVSSYPAPLEDANVRTVADMAQRFACPVGLSDHTPGTAAAVAAVALGASVIEKH
FTLARADGGPDAAFSLEPAEFAALVRDCKAAWRALGRAQYDLVGAERGNVQFRRSLYVAADVKAGEPLTRLNVRSIRPGD
GLPPAELEAVLGRPATRDLRRGEPLAWDMVSR

Sequences:

>Translated_352_residues
MSTHPQVEIAGRKVGAGHEPFVICELSGNHNGSLERALAMIDAAAATGCDAVKIQTYTADTITMDVDRPEFRIRGGLWDG
RSLYELYREAQTPYEWHAALFRRARELGVILFSSPFDETAVDLLAGLDAPAYKIASFEAVDLPLIRYAASKGKPLIISTG
MANLAEIEAARDAALSAGAPGVVLLHCVSSYPAPLEDANVRTVADMAQRFACPVGLSDHTPGTAAAVAAVALGASVIEKH
FTLARADGGPDAAFSLEPAEFAALVRDCKAAWRALGRAQYDLVGAERGNVQFRRSLYVAADVKAGEPLTRLNVRSIRPGD
GLPPAELEAVLGRPATRDLRRGEPLAWDMVSR
>Mature_351_residues
STHPQVEIAGRKVGAGHEPFVICELSGNHNGSLERALAMIDAAAATGCDAVKIQTYTADTITMDVDRPEFRIRGGLWDGR
SLYELYREAQTPYEWHAALFRRARELGVILFSSPFDETAVDLLAGLDAPAYKIASFEAVDLPLIRYAASKGKPLIISTGM
ANLAEIEAARDAALSAGAPGVVLLHCVSSYPAPLEDANVRTVADMAQRFACPVGLSDHTPGTAAAVAAVALGASVIEKHF
TLARADGGPDAAFSLEPAEFAALVRDCKAAWRALGRAQYDLVGAERGNVQFRRSLYVAADVKAGEPLTRLNVRSIRPGDG
LPPAELEAVLGRPATRDLRRGEPLAWDMVSR

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=346, Percent_Identity=31.2138728323699, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI21357081, Length=260, Percent_Identity=33.8461538461538, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 37574; Mature: 37443

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHPQVEIAGRKVGAGHEPFVICELSGNHNGSLERALAMIDAAAATGCDAVKIQTYTAD
CCCCCCEEECCEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECC
TITMDVDRPEFRIRGGLWDGRSLYELYREAQTPYEWHAALFRRARELGVILFSSPFDETA
EEEEECCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCHHH
VDLLAGLDAPAYKIASFEAVDLPLIRYAASKGKPLIISTGMANLAEIEAARDAALSAGAP
HHHHHCCCCCCEEECCCCCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
GVVLLHCVSSYPAPLEDANVRTVADMAQRFACPVGLSDHTPGTAAAVAAVALGASVIEKH
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FTLARADGGPDAAFSLEPAEFAALVRDCKAAWRALGRAQYDLVGAERGNVQFRRSLYVAA
HHEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEEE
DVKAGEPLTRLNVRSIRPGDGLPPAELEAVLGRPATRDLRRGEPLAWDMVSR
ECCCCCCHHCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHCCCCCCHHHCCC
>Mature Secondary Structure 
STHPQVEIAGRKVGAGHEPFVICELSGNHNGSLERALAMIDAAAATGCDAVKIQTYTAD
CCCCCEEECCEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECC
TITMDVDRPEFRIRGGLWDGRSLYELYREAQTPYEWHAALFRRARELGVILFSSPFDETA
EEEEECCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCHHH
VDLLAGLDAPAYKIASFEAVDLPLIRYAASKGKPLIISTGMANLAEIEAARDAALSAGAP
HHHHHCCCCCCEEECCCCCCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCC
GVVLLHCVSSYPAPLEDANVRTVADMAQRFACPVGLSDHTPGTAAAVAAVALGASVIEKH
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
FTLARADGGPDAAFSLEPAEFAALVRDCKAAWRALGRAQYDLVGAERGNVQFRRSLYVAA
HHEEECCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEEEE
DVKAGEPLTRLNVRSIRPGDGLPPAELEAVLGRPATRDLRRGEPLAWDMVSR
ECCCCCCHHCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]