Click here to switch to the map view.

The map label for this gene is flmH [C]

Identifier: 197106061

GI number: 197106061

Start: 2989974

End: 2990549

Strand: Reverse

Name: flmH [C]

Synonym: PHZ_c2600

Alternate gene names: 197106061

Gene position: 2990549-2989974 (Counterclockwise)

Preceding gene: 197106062

Following gene: 197106059

Centisome position: 74.83

GC content: 70.49

Gene sequence:

>576_bases
ATGAGCGTCCGGCTGCGCAAGGTCGAGCACGAGGACAGCGCCCGCCTGCTGGAGTGGCGCAACTCGCCCGACGTGTCGGC
CTTCATGTACACCGACCACCGCATCGGGCAGGCCGAGCACGACCGCTGGTTCGCCGCGGCGCTGACGGCCGAGGACCGCC
GGTACTGGATCATCGAGATGGACGGCCGGCCGGTGGGCCTGGCGAACCTGACCAGGATCGATCCCATCGTGCGCCGCTGC
GACTGGGCCTACTATCTGGCCGACCCGTCCACCCGCGGGCGGGGCGTCGGCGCGCAGGTCGAGTACATCGTCCTGCGCCA
CGTCTTCGAGACGATGAACTTCAACAAGCTGTGGTGCGAGGTCCTCAAGGAGAACGAGGCCGTCTGGAAGCTGCACGAGA
GCTTCGGCTTCCGGCGCGAGGCCGAGTACCGCGAGCACGTCTGCAAGGGCGGGCGGTTCCAGGACGTGGTGGGCCTGGGC
ATGCTCAAGGCCGACTGGGCGGGGGCCAGGCCCGCCGTCGAGGCGCGGCTGCGCGAGAAGGGGATCGACCCCGCCGCCCT
GCCGGACGCGCCCTAG

Upstream 100 bases:

>100_bases
GCGACGGTCTGCCTCCGGCTGAGCTGGAGGCGGTGCTGGGCCGCCCCGCGACGCGGGACCTGAGGCGGGGGGAGCCCCTG
GCGTGGGATATGGTGAGCCG

Downstream 100 bases:

>100_bases
ACGCGGGGCTCGCCGCCCCAGCCAGCCAGGTCCGGGCGGCTGCTCACGAAGGCGCGCACGTCGTCCGAGGTGAAGGCGGG
GTTGCGCGGATACAGCGCCT

Product: flagellin modification protein FlmH

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: Pseudaminic Acid Biosynthesis N-Acetyl Transferase; Acetyltransferase; Flagellin Protein FlmH; Spermidine N1-Acetyltransferase; GNAT Family Acetyltransferase; GCN5-Like N-Acetyltransferase; MaoC-Like Dehydratase; Gcn5-Like N-Acetyltransferase; Flagellar Protein FlaG; Flagellar Protein G FLAG; Flagellar Biosynthesis Protein G; Spermidine N(1)-Acetyltransferase; Spermidine Acetyltransferase; Diamine Acetyltransferase; Acetyltransferase FlmH; Acetyltransferase-Like Protein

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSVRLRKVEHEDSARLLEWRNSPDVSAFMYTDHRIGQAEHDRWFAAALTAEDRRYWIIEMDGRPVGLANLTRIDPIVRRC
DWAYYLADPSTRGRGVGAQVEYIVLRHVFETMNFNKLWCEVLKENEAVWKLHESFGFRREAEYREHVCKGGRFQDVVGLG
MLKADWAGARPAVEARLREKGIDPAALPDAP

Sequences:

>Translated_191_residues
MSVRLRKVEHEDSARLLEWRNSPDVSAFMYTDHRIGQAEHDRWFAAALTAEDRRYWIIEMDGRPVGLANLTRIDPIVRRC
DWAYYLADPSTRGRGVGAQVEYIVLRHVFETMNFNKLWCEVLKENEAVWKLHESFGFRREAEYREHVCKGGRFQDVVGLG
MLKADWAGARPAVEARLREKGIDPAALPDAP
>Mature_190_residues
SVRLRKVEHEDSARLLEWRNSPDVSAFMYTDHRIGQAEHDRWFAAALTAEDRRYWIIEMDGRPVGLANLTRIDPIVRRCD
WAYYLADPSTRGRGVGAQVEYIVLRHVFETMNFNKLWCEVLKENEAVWKLHESFGFRREAEYREHVCKGGRFQDVVGLGM
LKADWAGARPAVEARLREKGIDPAALPDAP

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787867, Length=165, Percent_Identity=22.4242424242424, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 22114; Mature: 21983

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRLRKVEHEDSARLLEWRNSPDVSAFMYTDHRIGQAEHDRWFAAALTAEDRRYWIIEM
CCCEECCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCEEEEEEE
DGRPVGLANLTRIDPIVRRCDWAYYLADPSTRGRGVGAQVEYIVLRHVFETMNFNKLWCE
CCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHH
VLKENEAVWKLHESFGFRREAEYREHVCKGGRFQDVVGLGMLKADWAGARPAVEARLREK
HHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHCCCEECCCCCCCHHHHHHHHHC
GIDPAALPDAP
CCCCCCCCCCC
>Mature Secondary Structure 
SVRLRKVEHEDSARLLEWRNSPDVSAFMYTDHRIGQAEHDRWFAAALTAEDRRYWIIEM
CCEECCCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCEEEEEEE
DGRPVGLANLTRIDPIVRRCDWAYYLADPSTRGRGVGAQVEYIVLRHVFETMNFNKLWCE
CCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHH
VLKENEAVWKLHESFGFRREAEYREHVCKGGRFQDVVGLGMLKADWAGARPAVEARLREK
HHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHCCCEECCCCCCCHHHHHHHHHC
GIDPAALPDAP
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA