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The map label for this gene is pdhR [H]

Identifier: 197106023

GI number: 197106023

Start: 2943333

End: 2944100

Strand: Direct

Name: pdhR [H]

Synonym: PHZ_c2562

Alternate gene names: 197106023

Gene position: 2943333-2944100 (Clockwise)

Preceding gene: 197106021

Following gene: 197106026

Centisome position: 73.65

GC content: 68.36

Gene sequence:

>768_bases
GTGTCTGAAAGTCTTCTCGGCGGTCACGTCCGCATCCCAAAGACCGCGGAGGTGCTCGCCAGCCGGATACGGAAGCGGAT
CATCAACGGGGAACTCAAGGCCGGGGACAAGCTCCCCCCCGAGGCGAACCTCATCACCGAGTTCGAGGTCTCCCGACCCA
CCATCCGGGAGGCGATCCGCATCCTTGAGTCGGAGGGGTTGATCAGCGTCTCCCGCGGCGCCCGCGGCGGCGCCCGGGTC
AACGCCGCCTCCACCGAGCTGGTCACCCGCGCCGCCGGTCTCGCCCTGCAAGCGCGGAACGCGACCTTGAAGGACATCTA
CGAGGCGCGCGCGCTCATCGAACCGCCCGCCGCGCGCCTGGCAGCCGAGCGGAGAAGCAAGCAGGCGTCCGCAGCCCTCC
GCGCCCACATCGCCGTCGAGTGGGCCGCCGGGGAGGACGACGTGCTCCGGGCGAAGGCCGTCGCCGAGTTCCACCGCATC
CTCCTGGAGGAATGCGGCAACGTCGCCTTGGGCATGGTCGGCACCGCCCTGCAAGCCGTAGTTGAGCAACACATGGAACT
GGCCTACCGGCGTGACCGCAGCCGGCAGAGGCAGAACACCTTGAAGCTCATCCAAGTGGGTCTGCGTTCACATGAGAAGC
TGGCGGACCTGATCGAGCAGGGCGATGGCCCCGGCGCCGAGGCCCACTGGGTCGACCACATGGCCAAGGCGGGCTCGTTC
TGGGTCGGCGCCGTCGGAAAGGCCACAGTCCTAGACGTTCTCGAGTAG

Upstream 100 bases:

>100_bases
CCATATCGTCCTCAGGCCGCCTCGACAACACGTCGGATCACTTGTCTGACTCAGCTGCCTCAATCTAAGGTAAGGCCGAA
CCTGGGGGTCAAGAACGCAA

Downstream 100 bases:

>100_bases
GACCGGCGGGCGCCGCGGCGCCCCCGCACCCCCTTCTGGGTCAATGCCTCCCGGACGTTGCGGGCGCCGCATCGCTGCTC
CAGACGATCTCCGCCTCCTG

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSESLLGGHVRIPKTAEVLASRIRKRIINGELKAGDKLPPEANLITEFEVSRPTIREAIRILESEGLISVSRGARGGARV
NAASTELVTRAAGLALQARNATLKDIYEARALIEPPAARLAAERRSKQASAALRAHIAVEWAAGEDDVLRAKAVAEFHRI
LLEECGNVALGMVGTALQAVVEQHMELAYRRDRSRQRQNTLKLIQVGLRSHEKLADLIEQGDGPGAEAHWVDHMAKAGSF
WVGAVGKATVLDVLE

Sequences:

>Translated_255_residues
MSESLLGGHVRIPKTAEVLASRIRKRIINGELKAGDKLPPEANLITEFEVSRPTIREAIRILESEGLISVSRGARGGARV
NAASTELVTRAAGLALQARNATLKDIYEARALIEPPAARLAAERRSKQASAALRAHIAVEWAAGEDDVLRAKAVAEFHRI
LLEECGNVALGMVGTALQAVVEQHMELAYRRDRSRQRQNTLKLIQVGLRSHEKLADLIEQGDGPGAEAHWVDHMAKAGSF
WVGAVGKATVLDVLE
>Mature_254_residues
SESLLGGHVRIPKTAEVLASRIRKRIINGELKAGDKLPPEANLITEFEVSRPTIREAIRILESEGLISVSRGARGGARVN
AASTELVTRAAGLALQARNATLKDIYEARALIEPPAARLAAERRSKQASAALRAHIAVEWAAGEDDVLRAKAVAEFHRIL
LEECGNVALGMVGTALQAVVEQHMELAYRRDRSRQRQNTLKLIQVGLRSHEKLADLIEQGDGPGAEAHWVDHMAKAGSFW
VGAVGKATVLDVLE

Specific function: Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786303, Length=188, Percent_Identity=31.3829787234043, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994955, Length=207, Percent_Identity=28.5024154589372, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI87082208, Length=165, Percent_Identity=33.9393939393939, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27618; Mature: 27487

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESLLGGHVRIPKTAEVLASRIRKRIINGELKAGDKLPPEANLITEFEVSRPTIREAIR
CCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
ILESEGLISVSRGARGGARVNAASTELVTRAAGLALQARNATLKDIYEARALIEPPAARL
HHHCCCCEEECCCCCCCCEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHH
AAERRSKQASAALRAHIAVEWAAGEDDVLRAKAVAEFHRILLEECGNVALGMVGTALQAV
HHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VEQHMELAYRRDRSRQRQNTLKLIQVGLRSHEKLADLIEQGDGPGAEAHWVDHMAKAGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCE
WVGAVGKATVLDVLE
EECCCCHHHHHHHCC
>Mature Secondary Structure 
SESLLGGHVRIPKTAEVLASRIRKRIINGELKAGDKLPPEANLITEFEVSRPTIREAIR
CCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
ILESEGLISVSRGARGGARVNAASTELVTRAAGLALQARNATLKDIYEARALIEPPAARL
HHHCCCCEEECCCCCCCCEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHH
AAERRSKQASAALRAHIAVEWAAGEDDVLRAKAVAEFHRILLEECGNVALGMVGTALQAV
HHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
VEQHMELAYRRDRSRQRQNTLKLIQVGLRSHEKLADLIEQGDGPGAEAHWVDHMAKAGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCE
WVGAVGKATVLDVLE
EECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]