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The map label for this gene is paaG [H]

Identifier: 197106005

GI number: 197106005

Start: 2920132

End: 2920950

Strand: Reverse

Name: paaG [H]

Synonym: PHZ_c2544

Alternate gene names: 197106005

Gene position: 2920950-2920132 (Counterclockwise)

Preceding gene: 197106007

Following gene: 197106004

Centisome position: 73.09

GC content: 69.72

Gene sequence:

>819_bases
ATGAGCCGAAGCGTTCTGGAGGCCGTGCAGGACGGGGTGATGACCATCACGCTGAACCGTCCCGAGCGGCTGAACGCCAT
GAACGGCGAACTGATGGAGCAACTGCTCGAGGCCGTGCAGCGGGCCGCCGCCGACCCCAAGGTCGCTTGCGTCGTGCTGA
CGGGCGCCGGCCGCGGCTTCTGCTCCGGAGGCGACCTGAAGAACAAGGACGCGGAGATCGCCGCGGACGCCCTGTTGCCG
CCGGAGCAGCGGAAGCGGCCGCAGACCATCGAGGCCAAGATCGCCAGGTTGCGGCGGCTGACGGAGGCGGCGCGCCTGCT
GCACGACATGCCAAAGCCCACCGTCGCGATGATCAACGGCGCCTGTGCAGGGGCCGGACTGTCGCTGGCCGGAGCCTGCG
ACCTGCGGATCGCCGCTCAGTCAGCCGTGATCACGAGCGCCTTCGGCAAGGCCGGCCTGTCGGGGGACTTCGGCGGCAGC
TGGTTCTGGTCGCGGATACTCGGGGCCGCGAAGGTTCGGGAGCTGTACCTGCTCTCGGAGCGGCGCACCGCGGCGGAGGC
GCTGGCGTTCGGCCTGGTGCACCGTGTGGTTCCGGACGAGGAGCTGCTGACGCACGTGCAGGCCCTGACCCTGAGCATCG
CCACGGGTCCGACGCACGCCTACGGCTTCATGAAGCGCAACCTGGCCGCGGCCGAGGATGGCGCCCTCGAGGAGGTGTTG
GATCTGGAAGCGACCACCATGACCCTGTGCAGCTACGAGATCGAGGAGCGTCGCCTCTTGGAAGCGGCCCAGGCCGCGAC
GCGTGGCCCGCCTTCCTGA

Upstream 100 bases:

>100_bases
CAGCGCCAGTTTCATCCCTGTTCCCCTTTTAATTAGTATGATGAGTTATACGATACGGCGCGGCGCGGTTGAAGACGCCG
CATTGGCGTGGGAGGGACCG

Downstream 100 bases:

>100_bases
GGGCCGCGCCTTGTACGGTCTCGCGGAATGGGTATACGTAGTTAGCTAATAAAAAGAATTGGAGGCGCGACTGATCTCGT
GGTCGCGGACAGGGATGAAG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSRSVLEAVQDGVMTITLNRPERLNAMNGELMEQLLEAVQRAAADPKVACVVLTGAGRGFCSGGDLKNKDAEIAADALLP
PEQRKRPQTIEAKIARLRRLTEAARLLHDMPKPTVAMINGACAGAGLSLAGACDLRIAAQSAVITSAFGKAGLSGDFGGS
WFWSRILGAAKVRELYLLSERRTAAEALAFGLVHRVVPDEELLTHVQALTLSIATGPTHAYGFMKRNLAAAEDGALEEVL
DLEATTMTLCSYEIEERRLLEAAQAATRGPPS

Sequences:

>Translated_272_residues
MSRSVLEAVQDGVMTITLNRPERLNAMNGELMEQLLEAVQRAAADPKVACVVLTGAGRGFCSGGDLKNKDAEIAADALLP
PEQRKRPQTIEAKIARLRRLTEAARLLHDMPKPTVAMINGACAGAGLSLAGACDLRIAAQSAVITSAFGKAGLSGDFGGS
WFWSRILGAAKVRELYLLSERRTAAEALAFGLVHRVVPDEELLTHVQALTLSIATGPTHAYGFMKRNLAAAEDGALEEVL
DLEATTMTLCSYEIEERRLLEAAQAATRGPPS
>Mature_271_residues
SRSVLEAVQDGVMTITLNRPERLNAMNGELMEQLLEAVQRAAADPKVACVVLTGAGRGFCSGGDLKNKDAEIAADALLPP
EQRKRPQTIEAKIARLRRLTEAARLLHDMPKPTVAMINGACAGAGLSLAGACDLRIAAQSAVITSAFGKAGLSGDFGGSW
FWSRILGAAKVRELYLLSERRTAAEALAFGLVHRVVPDEELLTHVQALTLSIATGPTHAYGFMKRNLAAAEDGALEEVLD
LEATTMTLCSYEIEERRLLEAAQAATRGPPS

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=262, Percent_Identity=31.2977099236641, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI45643119, Length=214, Percent_Identity=29.9065420560748, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI260275230, Length=214, Percent_Identity=29.9065420560748, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI260274832, Length=214, Percent_Identity=29.9065420560748, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=25.7028112449799, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI37594469, Length=155, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI37594471, Length=155, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI25453481, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI51538573, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI4757966, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI51538581, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI157694516, Length=242, Percent_Identity=26.0330578512397, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI213417737, Length=242, Percent_Identity=26.0330578512397, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI4757968, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI49355787, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221136756, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221136753, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221307494, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787660, Length=243, Percent_Identity=38.6831275720165, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788597, Length=199, Percent_Identity=35.1758793969849, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787659, Length=240, Percent_Identity=30.8333333333333, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI221142681, Length=210, Percent_Identity=31.4285714285714, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790281, Length=204, Percent_Identity=26.9607843137255, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17534483, Length=246, Percent_Identity=29.6747967479675, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536985, Length=241, Percent_Identity=28.2157676348548, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17535521, Length=232, Percent_Identity=27.1551724137931, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=191, Percent_Identity=34.0314136125654, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25145438, Length=260, Percent_Identity=29.2307692307692, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=195, Percent_Identity=28.2051282051282, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=213, Percent_Identity=27.2300469483568, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=235, Percent_Identity=31.063829787234, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653477, Length=235, Percent_Identity=31.063829787234, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357171, Length=222, Percent_Identity=29.2792792792793, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24654903, Length=238, Percent_Identity=26.0504201680672, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920382, Length=231, Percent_Identity=26.8398268398268, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24650670, Length=216, Percent_Identity=30.5555555555556, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653139, Length=227, Percent_Identity=28.6343612334802, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19922422, Length=209, Percent_Identity=26.7942583732057, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28978; Mature: 28846

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSVLEAVQDGVMTITLNRPERLNAMNGELMEQLLEAVQRAAADPKVACVVLTGAGRGF
CCHHHHHHHHCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
CSGGDLKNKDAEIAADALLPPEQRKRPQTIEAKIARLRRLTEAARLLHDMPKPTVAMING
CCCCCCCCCCHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHCCC
ACAGAGLSLAGACDLRIAAQSAVITSAFGKAGLSGDFGGSWFWSRILGAAKVRELYLLSE
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRTAAEALAFGLVHRVVPDEELLTHVQALTLSIATGPTHAYGFMKRNLAAAEDGALEEVL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHHH
DLEATTMTLCSYEIEERRLLEAAQAATRGPPS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRSVLEAVQDGVMTITLNRPERLNAMNGELMEQLLEAVQRAAADPKVACVVLTGAGRGF
CHHHHHHHHCCEEEEEECCCHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
CSGGDLKNKDAEIAADALLPPEQRKRPQTIEAKIARLRRLTEAARLLHDMPKPTVAMING
CCCCCCCCCCHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHCCC
ACAGAGLSLAGACDLRIAAQSAVITSAFGKAGLSGDFGGSWFWSRILGAAKVRELYLLSE
CCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRTAAEALAFGLVHRVVPDEELLTHVQALTLSIATGPTHAYGFMKRNLAAAEDGALEEVL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHHH
DLEATTMTLCSYEIEERRLLEAAQAATRGPPS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]