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The map label for this gene is cirA [H]

Identifier: 197105981

GI number: 197105981

Start: 2893030

End: 2895264

Strand: Reverse

Name: cirA [H]

Synonym: PHZ_c2520

Alternate gene names: 197105981

Gene position: 2895264-2893030 (Counterclockwise)

Preceding gene: 197105984

Following gene: 197105980

Centisome position: 72.45

GC content: 66.44

Gene sequence:

>2235_bases
ATGCACATCGTAAAATCCGGCGGCGCGCGCGCGCGCCTGGCGCTGCTCATTGGCACGGCGGTCGGTCTGGCCGCGCCGTC
GCTCGCATACGGACAGGACGCCGCCTCGGCGCAGGTCGCCGCGGTCGAGGAGGTGATCGTCACGGCTCAGCGGCGCGAGG
AGCGTCTCCAGGACGTTCCGGCCGCCGTGAGCGCCTACACGGGGAACCAACTGGAGCGGCTGGGCATCGAGGGCTCGAAG
GAGCTCTCGCAGGTCACCCCGGGACTGAACTTCACCCAGTCGGTGTTTTCGCCGCAGCCGACCATCCGCGGCATCGGCGT
CCGCGGCGTGGGCGCTGGGGATGAATCGGTGGTGCCCGTCTACATCGACGGCGTCTACGTCTCGTTCATCGCCGCCTCGG
ACCTGCAGTTCAACAACATCGAGCGGATCGAGGTGCTGAAGGGGCCGCAAGGGGCGCTCCTCGGCCGCAACGCCACGGGC
GGGGCGATCAACGTCATCACCAAGACGCCTCGGGAGGGCTTCGAGGGCCGCGCGTCGGTCAGCTACGGCAGCTTCGACGA
GATCATCGGCAAGGCCTATGTTTCGGGCGGCACCGATACGATCGCCGGCGACCTCGCGTTCTACGGGGTCAAGGACGACG
GCTATATCGACGACCCGCTGCGGAACGACACCTACGGCGCGGTGGAGAACTACTCGGTACGCAGCAAGCTCGTGGTGCGG
CCGACCGACGTCGTCGAGCTGCGCCTCTCGGCGGGTTACACCAACAACGTCGAGTCGACCGGCGAGGCCTACCGGCTTCC
CAACGGCAACACCGTGGGAGCCCGGGTTCCCGGTAACACGGTGACCACGCGCGCCTTCGACTCCACGCTCTCCTACCACC
CCTACAACAAGCTGCGGAGCGCCACCGCGTCGGTGACAGGTATCTTCCGGCTTGAGCCGTTCACGATCACATCGGTCACC
GGCTTTGCGGACAACAAGCTGCGCATCAAGGCCGACTCCGACGGCACGCCGCTGGAGATCGCCACGCTCACCTACGTCCA
GGTGTCGGACAACATCTATCAGGAGGTGTACGCCACCTCGAACAACGACGGCCCCTTCAGCTGGATCGCCGGCGCCGTCT
ACTTCCGCGACACCTCGGGAATGAGCCCCCAGTCCACCACCTACAGCCGGCCGGTCTCGCTGGCCGGCGTGGTAGGCAAC
CAGGCGATCAGCGTGACCCGGCCGCGGATCGATACCGACGCCTTCGCTCTCTACATGCAGGGATCGCTGAAGCTCGGTGA
GGCCTGGACGGTCACGCTCGGCGGCCGCTACAGCCACGAGACCAAGAAGTACCGGAGCCGGGTCGGCGCGACGACGATCA
CCACCCTGAGCGGCGAGAAGACCTTCGAGGACTTCAGCCCGACGGCGGTGATCCAGTACCAGCCAGATCCGCGGCTCAAC
CTCTATGCGAAGGCCGGCCGCGCCTTCAAGAGCGGCGTCTTCAACGCCAGCGCCTCGAACCCGGCGGCGGCCGTGCCGGT
CGATCCCGAGAAGGTCACTCAGTACGAGGTCGGCGTGAAATCCGATCCCACCCGCTGGCTGCGCCTGAACGCGGCGGCCT
ACTACACCGACTACAACGGGCTGCAGTCGAACGTCCGCGATCCGGTCACCCTGTCGTCCGCGCTGCAGAACGCCGGCGGC
GCCGACATCTACGGCCTGGAGGGCGAGGCCTTCGTCCGGGCCAGCGACAACTTGAACGTCCGCCTCGGACTGTCGTGGAT
CAAGGGCGAGTACAAGGACTTCCCGTCCTCGCTCGTCTACCTGCCGCAGACGGCGGTCAATCCGCCGGCGTCGACGCCCT
GCGTGCTCGGCTCTGGCGCGCTGGCCGGCGGCAACCGGTCCGCGTTCTGCAACGTGTCCGGTAACGACATCATCCGCACG
CCGTTCCTGACCGCCAACGTGGGTTTCGACTACACCCTCGACACCGAGGCCGGCGAAATCGTCTTCACCGGCAACGCCTA
CTACAAGGGCAAGTCCTACTGGGACACGCTGAACTACTTCAAGGAAGACGCCATCTGGCTGGTGAATGGGGACATCACCT
GGAACCTGCCGGGCGACCGGATTTCGCTCTCGGTCTGGGGTGAGAACCTCCTCGACGAAACCTACAGCCTCACCCGCGTG
ATCTCGCCTTCGGGCGAAACCCAGGTGCTGGCCAAACCCCGCACAACCGGGGTGAAGGTGTCCTACGCCTGGTAG

Upstream 100 bases:

>100_bases
TCTATTATATAAATATATTTGATCATCAGCCGGCGCCGGGCCATCCTTCGCTCGTCGAGAAGAAAAAGGGCTCAAGGCCC
CACGACGTAGGGAGGGTCAG

Downstream 100 bases:

>100_bases
ACTGATCCTCCCCCCTGGGCGCGGCGGTTCCGGCCGTCGCGCCCGTCTTCGTTGCTGACATACGGTTCGCCCGATCATGC
CCAACCGCCTGGACGCGCCC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 744; Mature: 744

Protein sequence:

>744_residues
MHIVKSGGARARLALLIGTAVGLAAPSLAYGQDAASAQVAAVEEVIVTAQRREERLQDVPAAVSAYTGNQLERLGIEGSK
ELSQVTPGLNFTQSVFSPQPTIRGIGVRGVGAGDESVVPVYIDGVYVSFIAASDLQFNNIERIEVLKGPQGALLGRNATG
GAINVITKTPREGFEGRASVSYGSFDEIIGKAYVSGGTDTIAGDLAFYGVKDDGYIDDPLRNDTYGAVENYSVRSKLVVR
PTDVVELRLSAGYTNNVESTGEAYRLPNGNTVGARVPGNTVTTRAFDSTLSYHPYNKLRSATASVTGIFRLEPFTITSVT
GFADNKLRIKADSDGTPLEIATLTYVQVSDNIYQEVYATSNNDGPFSWIAGAVYFRDTSGMSPQSTTYSRPVSLAGVVGN
QAISVTRPRIDTDAFALYMQGSLKLGEAWTVTLGGRYSHETKKYRSRVGATTITTLSGEKTFEDFSPTAVIQYQPDPRLN
LYAKAGRAFKSGVFNASASNPAAAVPVDPEKVTQYEVGVKSDPTRWLRLNAAAYYTDYNGLQSNVRDPVTLSSALQNAGG
ADIYGLEGEAFVRASDNLNVRLGLSWIKGEYKDFPSSLVYLPQTAVNPPASTPCVLGSGALAGGNRSAFCNVSGNDIIRT
PFLTANVGFDYTLDTEAGEIVFTGNAYYKGKSYWDTLNYFKEDAIWLVNGDITWNLPGDRISLSVWGENLLDETYSLTRV
ISPSGETQVLAKPRTTGVKVSYAW

Sequences:

>Translated_744_residues
MHIVKSGGARARLALLIGTAVGLAAPSLAYGQDAASAQVAAVEEVIVTAQRREERLQDVPAAVSAYTGNQLERLGIEGSK
ELSQVTPGLNFTQSVFSPQPTIRGIGVRGVGAGDESVVPVYIDGVYVSFIAASDLQFNNIERIEVLKGPQGALLGRNATG
GAINVITKTPREGFEGRASVSYGSFDEIIGKAYVSGGTDTIAGDLAFYGVKDDGYIDDPLRNDTYGAVENYSVRSKLVVR
PTDVVELRLSAGYTNNVESTGEAYRLPNGNTVGARVPGNTVTTRAFDSTLSYHPYNKLRSATASVTGIFRLEPFTITSVT
GFADNKLRIKADSDGTPLEIATLTYVQVSDNIYQEVYATSNNDGPFSWIAGAVYFRDTSGMSPQSTTYSRPVSLAGVVGN
QAISVTRPRIDTDAFALYMQGSLKLGEAWTVTLGGRYSHETKKYRSRVGATTITTLSGEKTFEDFSPTAVIQYQPDPRLN
LYAKAGRAFKSGVFNASASNPAAAVPVDPEKVTQYEVGVKSDPTRWLRLNAAAYYTDYNGLQSNVRDPVTLSSALQNAGG
ADIYGLEGEAFVRASDNLNVRLGLSWIKGEYKDFPSSLVYLPQTAVNPPASTPCVLGSGALAGGNRSAFCNVSGNDIIRT
PFLTANVGFDYTLDTEAGEIVFTGNAYYKGKSYWDTLNYFKEDAIWLVNGDITWNLPGDRISLSVWGENLLDETYSLTRV
ISPSGETQVLAKPRTTGVKVSYAW
>Mature_744_residues
MHIVKSGGARARLALLIGTAVGLAAPSLAYGQDAASAQVAAVEEVIVTAQRREERLQDVPAAVSAYTGNQLERLGIEGSK
ELSQVTPGLNFTQSVFSPQPTIRGIGVRGVGAGDESVVPVYIDGVYVSFIAASDLQFNNIERIEVLKGPQGALLGRNATG
GAINVITKTPREGFEGRASVSYGSFDEIIGKAYVSGGTDTIAGDLAFYGVKDDGYIDDPLRNDTYGAVENYSVRSKLVVR
PTDVVELRLSAGYTNNVESTGEAYRLPNGNTVGARVPGNTVTTRAFDSTLSYHPYNKLRSATASVTGIFRLEPFTITSVT
GFADNKLRIKADSDGTPLEIATLTYVQVSDNIYQEVYATSNNDGPFSWIAGAVYFRDTSGMSPQSTTYSRPVSLAGVVGN
QAISVTRPRIDTDAFALYMQGSLKLGEAWTVTLGGRYSHETKKYRSRVGATTITTLSGEKTFEDFSPTAVIQYQPDPRLN
LYAKAGRAFKSGVFNASASNPAAAVPVDPEKVTQYEVGVKSDPTRWLRLNAAAYYTDYNGLQSNVRDPVTLSSALQNAGG
ADIYGLEGEAFVRASDNLNVRLGLSWIKGEYKDFPSSLVYLPQTAVNPPASTPCVLGSGALAGGNRSAFCNVSGNDIIRT
PFLTANVGFDYTLDTEAGEIVFTGNAYYKGKSYWDTLNYFKEDAIWLVNGDITWNLPGDRISLSVWGENLLDETYSLTRV
ISPSGETQVLAKPRTTGVKVSYAW

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=178, Percent_Identity=30.3370786516854, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79853; Mature: 79853

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIVKSGGARARLALLIGTAVGLAAPSLAYGQDAASAQVAAVEEVIVTAQRREERLQDVP
CEEECCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AAVSAYTGNQLERLGIEGSKELSQVTPGLNFTQSVFSPQPTIRGIGVRGVGAGDESVVPV
HHHHHCCCCCCEECCCCCCHHHHHHCCCCCHHHHHCCCCCCEEEEEEEEECCCCCCEEEE
YIDGVYVSFIAASDLQFNNIERIEVLKGPQGALLGRNATGGAINVITKTPREGFEGRASV
EECCEEEEEEEECCCCCCCCCEEEEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCEEE
SYGSFDEIIGKAYVSGGTDTIAGDLAFYGVKDDGYIDDPLRNDTYGAVENYSVRSKLVVR
CCCCHHHHHHHHEECCCCCEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
PTDVVELRLSAGYTNNVESTGEAYRLPNGNTVGARVPGNTVTTRAFDSTLSYHPYNKLRS
CCCEEEEEEECCCCCCCCCCCCEEECCCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHH
ATASVTGIFRLEPFTITSVTGFADNKLRIKADSDGTPLEIATLTYVQVSDNIYQEVYATS
HHCCEEEEEEECCEEEEEEECCCCCEEEEEECCCCCCEEEEEEEEEEECCHHHHHHEECC
NNDGPFSWIAGAVYFRDTSGMSPQSTTYSRPVSLAGVVGNQAISVTRPRIDTDAFALYMQ
CCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCEEEEECCCCCCCEEEEEEE
GSLKLGEAWTVTLGGRYSHETKKYRSRVGATTITTLSGEKTFEDFSPTAVIQYQPDPRLN
CCEEECCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEECCCCCEE
LYAKAGRAFKSGVFNASASNPAAAVPVDPEKVTQYEVGVKSDPTRWLRLNAAAYYTDYNG
EEEECCCHHHCCCCCCCCCCCCEECCCCHHHHEEEECCCCCCCCEEEEEEEEEEEECCCC
LQSNVRDPVTLSSALQNAGGADIYGLEGEAFVRASDNLNVRLGLSWIKGEYKDFPSSLVY
HHHCCCCCEEHHHHHHCCCCCEEEECCCCEEEEECCCCEEEEEEHHHCCCHHCCCCCEEE
LPQTAVNPPASTPCVLGSGALAGGNRSAFCNVSGNDIIRTPFLTANVGFDYTLDTEAGEI
CCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCEEECCEEEEECCCCEEECCCCCEE
VFTGNAYYKGKSYWDTLNYFKEDAIWLVNGDITWNLPGDRISLSVWGENLLDETYSLTRV
EECCCEEECCCHHHHHHHHHCCCEEEEEECCEEECCCCCEEEEEECCCHHHHHHHEEEEE
ISPSGETQVLAKPRTTGVKVSYAW
ECCCCCEEEEECCCCCCEEEEEEC
>Mature Secondary Structure
MHIVKSGGARARLALLIGTAVGLAAPSLAYGQDAASAQVAAVEEVIVTAQRREERLQDVP
CEEECCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AAVSAYTGNQLERLGIEGSKELSQVTPGLNFTQSVFSPQPTIRGIGVRGVGAGDESVVPV
HHHHHCCCCCCEECCCCCCHHHHHHCCCCCHHHHHCCCCCCEEEEEEEEECCCCCCEEEE
YIDGVYVSFIAASDLQFNNIERIEVLKGPQGALLGRNATGGAINVITKTPREGFEGRASV
EECCEEEEEEEECCCCCCCCCEEEEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCEEE
SYGSFDEIIGKAYVSGGTDTIAGDLAFYGVKDDGYIDDPLRNDTYGAVENYSVRSKLVVR
CCCCHHHHHHHHEECCCCCEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
PTDVVELRLSAGYTNNVESTGEAYRLPNGNTVGARVPGNTVTTRAFDSTLSYHPYNKLRS
CCCEEEEEEECCCCCCCCCCCCEEECCCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHH
ATASVTGIFRLEPFTITSVTGFADNKLRIKADSDGTPLEIATLTYVQVSDNIYQEVYATS
HHCCEEEEEEECCEEEEEEECCCCCEEEEEECCCCCCEEEEEEEEEEECCHHHHHHEECC
NNDGPFSWIAGAVYFRDTSGMSPQSTTYSRPVSLAGVVGNQAISVTRPRIDTDAFALYMQ
CCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCEEEEECCCCCCCEEEEEEE
GSLKLGEAWTVTLGGRYSHETKKYRSRVGATTITTLSGEKTFEDFSPTAVIQYQPDPRLN
CCEEECCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEECCCCCEE
LYAKAGRAFKSGVFNASASNPAAAVPVDPEKVTQYEVGVKSDPTRWLRLNAAAYYTDYNG
EEEECCCHHHCCCCCCCCCCCCEECCCCHHHHEEEECCCCCCCCEEEEEEEEEEEECCCC
LQSNVRDPVTLSSALQNAGGADIYGLEGEAFVRASDNLNVRLGLSWIKGEYKDFPSSLVY
HHHCCCCCEEHHHHHHCCCCCEEEECCCCEEEEECCCCEEEEEEHHHCCCHHCCCCCEEE
LPQTAVNPPASTPCVLGSGALAGGNRSAFCNVSGNDIIRTPFLTANVGFDYTLDTEAGEI
CCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCEEECCEEEEECCCCEEECCCCCEE
VFTGNAYYKGKSYWDTLNYFKEDAIWLVNGDITWNLPGDRISLSVWGENLLDETYSLTRV
EECCCEEECCCHHHHHHHHHCCCEEEEEECCEEECCCCCEEEEEECCCHHHHHHHEEEEE
ISPSGETQVLAKPRTTGVKVSYAW
ECCCCCEEEEECCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]