Click here to switch to the map view.

The map label for this gene is amiC [H]

Identifier: 197105958

GI number: 197105958

Start: 2861660

End: 2863147

Strand: Direct

Name: amiC [H]

Synonym: PHZ_c2497

Alternate gene names: 197105958

Gene position: 2861660-2863147 (Clockwise)

Preceding gene: 197105957

Following gene: 197105961

Centisome position: 71.61

GC content: 75.13

Gene sequence:

>1488_bases
ATGATCCGACTTTCTCGCCGCGCGTTCGCCGGCGCGCCGCTGGCGCTGGCCGCGTGCGCCACGGTTCCGGAGCGGGCGTT
CCGCCCAACGCCGGGCTGGCCCGACGCCACCGAGACCGCGGCCATGATCCGCCGCGGCGAGATCACGGCCGGACAGGCCG
TCCGCAGCGCGATCGACCGGACCCTCGCACTGCAGCCCAGGCTCAACTTCCTCGTCGCCTCCGATTTCGACCGGGCGCTC
GCCAGGGCCGCCACGGGACCCGGCGATGGCCCCTTCGCGGGCGTGCCCTTCCTCGTGAAGGACCTCGACGACTATCGCGG
CCTCCCGACCCGTTCGGGCTCGTTCTCGCAGCTGCCCCTGCCGCCCGCGCAGGGTCAGGGGCCGCTGATCGACGCCTTCG
AGCGCGCGGGCGTGGTCGTGATCGGCAAGTCCGCGACGCCCGAGTACGGCTTCCTGCCCACCACCGAGCCGGCGGCCTTC
GGACCCACGCGGAATCCGTGGGATCCGACCCGCTCCAGCGGCGGCTCGTCCGGCGGGGCGGCCGCCGCCGTGGCCGCAGG
CGCGGTCCCCTTCGCCCACGCCAGCGACGGCGGCGGTTCGATCCGCATCCCGGCCTCGTGCTGCGGTCTGTTCGGCCTGA
AGCCCTCCCGCGGCCGCATGGTCGGGGCCCGCGAGCAGACGAAGATCAGCGACCTGTCGGTGGACCACGTGCTGACCCGC
AGCGTCCGGGATTCCGCGGCCATGTTCGCCCTCACCGAGGACGCGGGCGAGGGCGCGCAGCACCCGCCCGTGGGCCTCGT
CACCGCCCCGCTCCGCCGCCGGCTGCGGGTGGGCCTCGTCATGGAGGGCATGGCCGGCAAGGCCCCCTCGCCCGAGGTCC
GGGCCGCCACCGAGGCCAGCGCGCGGCTGTTGGAGAGCCTCGGCCACACGGTGGTCCCGACCCGCTGGCCGACCGGTCCC
GAGTTCACCCAGGACTTCCTGCTGCTGTGGGCCTCGGGCGCCGCCCAGCTCGCCGGCGCCATCGGCAAGGCGGCCGGCCG
CCAGCCCGACACCACCCTCCTGGAGCCGTTCAGCCTGGGCATGGCCGAGATGTTCGCCAAGGCGCCGCCCGGCGCGCTGG
GCCAGGCAATGGAGCGGCTGCACGCCGCCGCCATGGCCTACGATCCCTGGTTCGTCGGCAACGGCCTCGACGTGGTGATG
TCCCCCGTCCTGTCTGCGCCGCCGCCGCCCCTGGGCTGGGTGGGGCCGGGCGTGCCCTTCGACACCCTGGTCGAGCGGCT
GACCGAGTACGTGGGCTACACGACCTATCACAACGTCACGGGCGCGCCGGCCATGAGCGTGCCGCTGAACTGGATCGGCG
CCGGCCTGCCGGTCGGCACGCAGTTCGCCGCCCGCGTCGGCCACGAGGCCCTGCTGTTCCAGCTCGCCTACCAGCTCGAG
GCGGCCCAGCCCTGGGCCGGCCGCCTGCCGCCGGTCCGCGCGCTCTAG

Upstream 100 bases:

>100_bases
CCGACCGCCGTTCCTGAGGCTTGGCGCCCGCCCCCCGATTGAGCCAAGCTCCGCCTTGACCGGCGCAAAGACCGGCTGAG
GAACTGCAGGGGGGCATCGC

Downstream 100 bases:

>100_bases
GCCGCCAGCCCCTGCAGGCGCGCGGCGGTCTCGCGCACCCGCTCGGGTCCGCCGAACAGCTGCCGGTTCAGGCCGATGCG
CTTGAACCAGTAGTGCAGGC

Product: 6-aminohexanoate-cyclic-dimer hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MIRLSRRAFAGAPLALAACATVPERAFRPTPGWPDATETAAMIRRGEITAGQAVRSAIDRTLALQPRLNFLVASDFDRAL
ARAATGPGDGPFAGVPFLVKDLDDYRGLPTRSGSFSQLPLPPAQGQGPLIDAFERAGVVVIGKSATPEYGFLPTTEPAAF
GPTRNPWDPTRSSGGSSGGAAAAVAAGAVPFAHASDGGGSIRIPASCCGLFGLKPSRGRMVGAREQTKISDLSVDHVLTR
SVRDSAAMFALTEDAGEGAQHPPVGLVTAPLRRRLRVGLVMEGMAGKAPSPEVRAATEASARLLESLGHTVVPTRWPTGP
EFTQDFLLLWASGAAQLAGAIGKAAGRQPDTTLLEPFSLGMAEMFAKAPPGALGQAMERLHAAAMAYDPWFVGNGLDVVM
SPVLSAPPPPLGWVGPGVPFDTLVERLTEYVGYTTYHNVTGAPAMSVPLNWIGAGLPVGTQFAARVGHEALLFQLAYQLE
AAQPWAGRLPPVRAL

Sequences:

>Translated_495_residues
MIRLSRRAFAGAPLALAACATVPERAFRPTPGWPDATETAAMIRRGEITAGQAVRSAIDRTLALQPRLNFLVASDFDRAL
ARAATGPGDGPFAGVPFLVKDLDDYRGLPTRSGSFSQLPLPPAQGQGPLIDAFERAGVVVIGKSATPEYGFLPTTEPAAF
GPTRNPWDPTRSSGGSSGGAAAAVAAGAVPFAHASDGGGSIRIPASCCGLFGLKPSRGRMVGAREQTKISDLSVDHVLTR
SVRDSAAMFALTEDAGEGAQHPPVGLVTAPLRRRLRVGLVMEGMAGKAPSPEVRAATEASARLLESLGHTVVPTRWPTGP
EFTQDFLLLWASGAAQLAGAIGKAAGRQPDTTLLEPFSLGMAEMFAKAPPGALGQAMERLHAAAMAYDPWFVGNGLDVVM
SPVLSAPPPPLGWVGPGVPFDTLVERLTEYVGYTTYHNVTGAPAMSVPLNWIGAGLPVGTQFAARVGHEALLFQLAYQLE
AAQPWAGRLPPVRAL
>Mature_495_residues
MIRLSRRAFAGAPLALAACATVPERAFRPTPGWPDATETAAMIRRGEITAGQAVRSAIDRTLALQPRLNFLVASDFDRAL
ARAATGPGDGPFAGVPFLVKDLDDYRGLPTRSGSFSQLPLPPAQGQGPLIDAFERAGVVVIGKSATPEYGFLPTTEPAAF
GPTRNPWDPTRSSGGSSGGAAAAVAAGAVPFAHASDGGGSIRIPASCCGLFGLKPSRGRMVGAREQTKISDLSVDHVLTR
SVRDSAAMFALTEDAGEGAQHPPVGLVTAPLRRRLRVGLVMEGMAGKAPSPEVRAATEASARLLESLGHTVVPTRWPTGP
EFTQDFLLLWASGAAQLAGAIGKAAGRQPDTTLLEPFSLGMAEMFAKAPPGALGQAMERLHAAAMAYDPWFVGNGLDVVM
SPVLSAPPPPLGWVGPGVPFDTLVERLTEYVGYTTYHNVTGAPAMSVPLNWIGAGLPVGTQFAARVGHEALLFQLAYQLE
AAQPWAGRLPPVRAL

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=195, Percent_Identity=29.7435897435897, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI222831590, Length=507, Percent_Identity=23.8658777120316, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538252, Length=460, Percent_Identity=24.3478260869565, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17537465, Length=297, Percent_Identity=27.9461279461279, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17556264, Length=232, Percent_Identity=30.6034482758621, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71990152, Length=413, Percent_Identity=24.9394673123487, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565337, Length=274, Percent_Identity=27.007299270073, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538254, Length=314, Percent_Identity=26.1146496815287, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556276, Length=246, Percent_Identity=29.2682926829268, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17556278, Length=246, Percent_Identity=29.2682926829268, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320448, Length=180, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI161078093, Length=492, Percent_Identity=26.8292682926829, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356731, Length=494, Percent_Identity=27.7327935222672, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45550774, Length=195, Percent_Identity=32.8205128205128, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24648435, Length=195, Percent_Identity=32.8205128205128, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24648437, Length=195, Percent_Identity=32.8205128205128, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644968, Length=199, Percent_Identity=35.1758793969849, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24652985, Length=196, Percent_Identity=32.6530612244898, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19922090, Length=196, Percent_Identity=32.6530612244898, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652981, Length=196, Percent_Identity=32.6530612244898, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24652983, Length=196, Percent_Identity=32.6530612244898, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648441, Length=126, Percent_Identity=37.3015873015873, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24648439, Length=126, Percent_Identity=37.3015873015873, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 51596; Mature: 51596

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLSRRAFAGAPLALAACATVPERAFRPTPGWPDATETAAMIRRGEITAGQAVRSAIDR
CCEECCHHHCCCCHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
TLALQPRLNFLVASDFDRALARAATGPGDGPFAGVPFLVKDLDDYRGLPTRSGSFSQLPL
HEECCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
PPAQGQGPLIDAFERAGVVVIGKSATPEYGFLPTTEPAAFGPTRNPWDPTRSSGGSSGGA
CCCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AAAVAAGAVPFAHASDGGGSIRIPASCCGLFGLKPSRGRMVGAREQTKISDLSVDHVLTR
HHHHHHCCCCCCCCCCCCCEEEECHHHHHHCCCCCCCCCEECCCCCCHHHHCCHHHHHHH
SVRDSAAMFALTEDAGEGAQHPPVGLVTAPLRRRLRVGLVMEGMAGKAPSPEVRAATEAS
HHHHHHEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHH
ARLLESLGHTVVPTRWPTGPEFTQDFLLLWASGAAQLAGAIGKAAGRQPDTTLLEPFSLG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCHHHHC
MAEMFAKAPPGALGQAMERLHAAAMAYDPWFVGNGLDVVMSPVLSAPPPPLGWVGPGVPF
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCCH
DTLVERLTEYVGYTTYHNVTGAPAMSVPLNWIGAGLPVGTQFAARVGHEALLFQLAYQLE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAQPWAGRLPPVRAL
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRLSRRAFAGAPLALAACATVPERAFRPTPGWPDATETAAMIRRGEITAGQAVRSAIDR
CCEECCHHHCCCCHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
TLALQPRLNFLVASDFDRALARAATGPGDGPFAGVPFLVKDLDDYRGLPTRSGSFSQLPL
HEECCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
PPAQGQGPLIDAFERAGVVVIGKSATPEYGFLPTTEPAAFGPTRNPWDPTRSSGGSSGGA
CCCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AAAVAAGAVPFAHASDGGGSIRIPASCCGLFGLKPSRGRMVGAREQTKISDLSVDHVLTR
HHHHHHCCCCCCCCCCCCCEEEECHHHHHHCCCCCCCCCEECCCCCCHHHHCCHHHHHHH
SVRDSAAMFALTEDAGEGAQHPPVGLVTAPLRRRLRVGLVMEGMAGKAPSPEVRAATEAS
HHHHHHEEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHH
ARLLESLGHTVVPTRWPTGPEFTQDFLLLWASGAAQLAGAIGKAAGRQPDTTLLEPFSLG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCHHHHC
MAEMFAKAPPGALGQAMERLHAAAMAYDPWFVGNGLDVVMSPVLSAPPPPLGWVGPGVPF
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCCCH
DTLVERLTEYVGYTTYHNVTGAPAMSVPLNWIGAGLPVGTQFAARVGHEALLFQLAYQLE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAQPWAGRLPPVRAL
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]