| Definition | Phenylobacterium zucineum HLK1, complete genome. |
|---|---|
| Accession | NC_011144 |
| Length | 3,996,255 |
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The map label for this gene is kduD [H]
Identifier: 197105911
GI number: 197105911
Start: 2801919
End: 2802680
Strand: Reverse
Name: kduD [H]
Synonym: PHZ_c2450
Alternate gene names: 197105911
Gene position: 2802680-2801919 (Counterclockwise)
Preceding gene: 197105912
Following gene: 197105909
Centisome position: 70.13
GC content: 72.31
Gene sequence:
>762_bases ATGAATCCTGGCCTCTTCAGCCTTCAGGGCAAGGTCGCCCTGGTCACCGGCGCCAACACCGGGCTCGGCCAGGGGATCGC CGTGGGCCTGGCGCAGGCGGGGGCGGACATCGTCGCCGTCGGCCGCAGCGCGCCCGACGAGACCGCCGAGATGGTGCGCA AGGCCGGCCGCGAGCTGCATGCCATCCGCGCCGACCTCGGCTCCACCGGGCCGCTCGCCGGCGTGGTGGAGGAGGCCTTC GCCGCCGCCGGCCAGGTGGACATCCTGGTCAACAACGCCGGCGTCATCCGCCGGGCCGACAGCCTCGACTTCACCGAAGA GGACTGGGACGCGGTGATGGACACCAACCTGAAGACGGTCTTCTTCCTGTCGCAGGCGGTGGCCCGGCGCTGGGTCGCCG CCGGCCGCGGCGGCAAGATCATCAACGTGGTCTCGATGCTGTCCTTCCAGGGCGGCATCCGGGTGCCGTCCTACACCGCC TCGAAGAGCGGCCTGGCGGGCCTGACCAAGCTGCTCTGCAACGAGTGGGCGGGGAAGGGCATCAACGTCAACGCCATCGC CCCCGGCTACTTCGCCACCAACAACACCGAGGCGCTGCGGGCCGACGAGGGCCGCTCCAGGGAGATCCTGGGCCGCATCC CGGCGGGCCGCTGGGGCGATCCCTCGGACCTCGCGGGCGCCGCCGTGTTCCTGGCGAGCGGCGCGTCCGACTACATGCAC GGCGCGATCGTCCCCGTGGACGGCGGCTGGCTGGCGCGGTGA
Upstream 100 bases:
>100_bases GCACCTCGAACTACGCCTTCATCTGGGCGATGGGCGGGGAGAACCTCGACTACACCGACATGCGCGTCCTCGACATCTGC CAGCTGAAGTGAGCCCCGAG
Downstream 100 bases:
>100_bases CTTACGTCCCCGGCTGCACGTAGGGGACCTTCGCGAAGAACCGCCGCTCGGCGCCGCGGGGGTCGTCCTCCAGGCGCGAG GGGACGTCGAAGACCATCGT
Product: 2-deoxy-D-gluconate 3-dehydrogenase
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 253; Mature: 253
Protein sequence:
>253_residues MNPGLFSLQGKVALVTGANTGLGQGIAVGLAQAGADIVAVGRSAPDETAEMVRKAGRELHAIRADLGSTGPLAGVVEEAF AAAGQVDILVNNAGVIRRADSLDFTEEDWDAVMDTNLKTVFFLSQAVARRWVAAGRGGKIINVVSMLSFQGGIRVPSYTA SKSGLAGLTKLLCNEWAGKGINVNAIAPGYFATNNTEALRADEGRSREILGRIPAGRWGDPSDLAGAAVFLASGASDYMH GAIVPVDGGWLAR
Sequences:
>Translated_253_residues MNPGLFSLQGKVALVTGANTGLGQGIAVGLAQAGADIVAVGRSAPDETAEMVRKAGRELHAIRADLGSTGPLAGVVEEAF AAAGQVDILVNNAGVIRRADSLDFTEEDWDAVMDTNLKTVFFLSQAVARRWVAAGRGGKIINVVSMLSFQGGIRVPSYTA SKSGLAGLTKLLCNEWAGKGINVNAIAPGYFATNNTEALRADEGRSREILGRIPAGRWGDPSDLAGAAVFLASGASDYMH GAIVPVDGGWLAR >Mature_253_residues MNPGLFSLQGKVALVTGANTGLGQGIAVGLAQAGADIVAVGRSAPDETAEMVRKAGRELHAIRADLGSTGPLAGVVEEAF AAAGQVDILVNNAGVIRRADSLDFTEEDWDAVMDTNLKTVFFLSQAVARRWVAAGRGGKIINVVSMLSFQGGIRVPSYTA SKSGLAGLTKLLCNEWAGKGINVNAIAPGYFATNNTEALRADEGRSREILGRIPAGRWGDPSDLAGAAVFLASGASDYMH GAIVPVDGGWLAR
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=34.6456692913386, Blast_Score=125, Evalue=5e-29, Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=34.6938775510204, Blast_Score=122, Evalue=2e-28, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=34.136546184739, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=30.3030303030303, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=31.6666666666667, Blast_Score=104, Evalue=9e-23, Organism=Homo sapiens, GI4503301, Length=248, Percent_Identity=31.4516129032258, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=31.0204081632653, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=30.2788844621514, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=28.740157480315, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=29.7619047619048, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=32.48730964467, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=30.1960784313725, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI20149619, Length=210, Percent_Identity=31.9047619047619, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI31542939, Length=261, Percent_Identity=29.1187739463602, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=33.5164835164835, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=27.319587628866, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI40254986, Length=199, Percent_Identity=27.1356783919598, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI142976729, Length=195, Percent_Identity=25.1282051282051, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI210032110, Length=196, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI7706318, Length=203, Percent_Identity=29.064039408867, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=64.1129032258064, Blast_Score=326, Evalue=1e-90, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=45.2, Blast_Score=213, Evalue=1e-56, Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=42.9133858267717, Blast_Score=178, Evalue=3e-46, Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=38.1526104417671, Blast_Score=145, Evalue=3e-36, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=35.4330708661417, Blast_Score=127, Evalue=9e-31, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=33.6065573770492, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=34.0163934426229, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=29.8804780876494, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=31.6, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=27.6, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=26.8, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=27.3076923076923, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=34.6938775510204, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=31.7647058823529, Blast_Score=127, Evalue=4e-30, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=33.469387755102, Blast_Score=121, Evalue=3e-28, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=27.4193548387097, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=32.0158102766798, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=32.2222222222222, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=31.3725490196078, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562910, Length=257, Percent_Identity=30.7392996108949, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=30.3501945525292, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=32.6923076923077, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=31.9391634980989, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=28, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=30.0751879699248, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=29.4573643410853, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.957528957529, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=28.1746031746032, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=31.25, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=30.3703703703704, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=30.6513409961686, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=27.34375, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=29.2307692307692, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=27.5862068965517, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=28.2945736434109, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=30.1158301158301, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=30.3030303030303, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=29.8449612403101, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=27.6041666666667, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=28.2945736434109, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=30.6878306878307, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538182, Length=267, Percent_Identity=30.3370786516854, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17508651, Length=259, Percent_Identity=28.957528957529, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=27.3684210526316, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI86565303, Length=266, Percent_Identity=27.8195488721804, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17555612, Length=259, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=25.9067357512953, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=34.010152284264, Blast_Score=96, Evalue=8e-21, Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=6e-14, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=35.0597609561753, Blast_Score=133, Evalue=1e-31, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=34.9593495934959, Blast_Score=128, Evalue=3e-30, Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=31.3725490196078, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=32.4110671936759, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=32.156862745098, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=32.5102880658436, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=30.5882352941176, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI18859837, Length=218, Percent_Identity=36.2385321100917, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=30.1587301587302, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=27.734375, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=32.1608040201005, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21357673, Length=192, Percent_Identity=28.125, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=31.0526315789474, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=31.0526315789474, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24584752, Length=198, Percent_Identity=29.7979797979798, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 26134; Mature: 26134
Theoretical pI: Translated: 5.84; Mature: 5.84
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNPGLFSLQGKVALVTGANTGLGQGIAVGLAQAGADIVAVGRSAPDETAEMVRKAGRELH CCCCEEEECCCEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH AIRADLGSTGPLAGVVEEAFAAAGQVDILVNNAGVIRRADSLDFTEEDWDAVMDTNLKTV HHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCHHHHHHHHCCCCHHH FFLSQAVARRWVAAGRGGKIINVVSMLSFQGGIRVPSYTASKSGLAGLTKLLCNEWAGKG HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC INVNAIAPGYFATNNTEALRADEGRSREILGRIPAGRWGDPSDLAGAAVFLASGASDYMH EEEEEECCCEEECCCCCEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHHC GAIVPVDGGWLAR CEEEEECCCCCCC >Mature Secondary Structure MNPGLFSLQGKVALVTGANTGLGQGIAVGLAQAGADIVAVGRSAPDETAEMVRKAGRELH CCCCEEEECCCEEEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH AIRADLGSTGPLAGVVEEAFAAAGQVDILVNNAGVIRRADSLDFTEEDWDAVMDTNLKTV HHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCHHHHHHHHCCCCHHH FFLSQAVARRWVAAGRGGKIINVVSMLSFQGGIRVPSYTASKSGLAGLTKLLCNEWAGKG HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC INVNAIAPGYFATNNTEALRADEGRSREILGRIPAGRWGDPSDLAGAAVFLASGASDYMH EEEEEECCCEEECCCCCEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHEECCCCHHHC GAIVPVDGGWLAR CEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 1766386 [H]