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The map label for this gene is hipA [C]

Identifier: 197105848

GI number: 197105848

Start: 2708063

End: 2709274

Strand: Direct

Name: hipA [C]

Synonym: PHZ_c2387

Alternate gene names: 197105848

Gene position: 2708063-2709274 (Clockwise)

Preceding gene: 197105847

Following gene: 197105852

Centisome position: 67.77

GC content: 68.81

Gene sequence:

>1212_bases
ATGCCCGGCCTCGACGTCTGGATCGGCGCCCGCCGGGTCGGCGCCATCACCTATCTTGGCGGGGACCGTTCCGTCTTCGC
CTTCGACGACGCCTACGCCGACGATCCCCGGCGGCCGACGCTCAGCCTGGTCTTCAAGAGCGCGGCTGGCGGCCTGCTCC
GCGAGGTTCGCCCGACCCGGGCGCGGGCCCATCCCTACTTTTCCAACCTGCTGCCGGAAGGCCCCCTGCGCGACTATCTT
GCGAAGCGCGCTGGCGTGAACCCGACCCGCGAACTGCACCTCCTGGCCATGCTCGGCGATGACCTGCCAGGGGCCGTCGT
CCTCACCGTCCAGGAGGAGGCGCCCCTGCCCCGCGACGCCGAGCCACGTCGCTTCTACGGCGGCGGCGAGCCGACCGCGC
TGCGCTTCTCCCTGGCCGGTGTTCAGCTGAAATTCTCGGCGGCTGAAAAGGCGCAGGGCGGTCTCACAATCCCGGCCCAC
GGCGTGGGCGGCGACTGGATCGTCAAGCTCCCTTCCTCCCGCTTCAACGGCGTCTCGGAGAACGAATTCTCCATGATGAC
CCTCGCGGCCGCCATTGGCATCGAGGTCCCGCAGGTGCGCCTGCTGTCGCTCGAAGATATCGAAGGCCTGCCCGAGGACA
TCGGCCGTCTTAAGGGGGCCGCCTACGCGGTTTCCCGTTTCGACCGCTCCCCGGAGGGTGAGCGCATTCACATCGAGGAC
TTCGCACAGGTGTTCGGCGTCTTTCCAGAAGCCAAGTACCAGCGCGCCTCCTATCGCAACATCGGTCAGGTCCTGTGGCG
GGAAACGGGCGAGCCGGGCTATGCGGAGTTCGTCCGACGCCTGGTGTTCAGCGCGCTGATCGGCAACGCCGACATGCACC
TCAAGAACTGGTCGCTCATCTATCGGGATGGACGAACGCCGAGCCTGGCGCCGGCATACGACCTCCTGTCCACAATAGCC
TATCTGCCGGACGACAACGCGGCGCTGAAGGTGGCGCGCAGCAAGGCCTGGACCGACTTCGACGCCGATGAACTCGCCGC
CCTCGCCGACGGCTCCGGCGCCCCGCAGCGACTGACGCTGCGGCTGGCGCGGGAGACCGTCGACGCCTTCCGGTCGGCCT
GGGCCAGCGAGGCGGCCCACCTGCCGATGGGCGACGACGTGCGCCAGGTGGTCGAGGCGCAGCTCGACCGGGTTCCGATC
GCCCGCGGCTGA

Upstream 100 bases:

>100_bases
ATGCGCTGACGCACCTGCGCCCGCTCCTGACTGACGCCGTGGTCCGCGGCAGCCGCAACAGGGCGCGGCCCGCCTACACT
CTGGACGACGAGGCCTGACC

Downstream 100 bases:

>100_bases
CGGAGCGCCGCCGACAGGCGCCCCAGACGACAGTCGCGGACAGGCCCGACAGCGTCATCCCAGCGCGCAGACAGCCTCGT
CGGCATGCCGGTCAAGGAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MPGLDVWIGARRVGAITYLGGDRSVFAFDDAYADDPRRPTLSLVFKSAAGGLLREVRPTRARAHPYFSNLLPEGPLRDYL
AKRAGVNPTRELHLLAMLGDDLPGAVVLTVQEEAPLPRDAEPRRFYGGGEPTALRFSLAGVQLKFSAAEKAQGGLTIPAH
GVGGDWIVKLPSSRFNGVSENEFSMMTLAAAIGIEVPQVRLLSLEDIEGLPEDIGRLKGAAYAVSRFDRSPEGERIHIED
FAQVFGVFPEAKYQRASYRNIGQVLWRETGEPGYAEFVRRLVFSALIGNADMHLKNWSLIYRDGRTPSLAPAYDLLSTIA
YLPDDNAALKVARSKAWTDFDADELAALADGSGAPQRLTLRLARETVDAFRSAWASEAAHLPMGDDVRQVVEAQLDRVPI
ARG

Sequences:

>Translated_403_residues
MPGLDVWIGARRVGAITYLGGDRSVFAFDDAYADDPRRPTLSLVFKSAAGGLLREVRPTRARAHPYFSNLLPEGPLRDYL
AKRAGVNPTRELHLLAMLGDDLPGAVVLTVQEEAPLPRDAEPRRFYGGGEPTALRFSLAGVQLKFSAAEKAQGGLTIPAH
GVGGDWIVKLPSSRFNGVSENEFSMMTLAAAIGIEVPQVRLLSLEDIEGLPEDIGRLKGAAYAVSRFDRSPEGERIHIED
FAQVFGVFPEAKYQRASYRNIGQVLWRETGEPGYAEFVRRLVFSALIGNADMHLKNWSLIYRDGRTPSLAPAYDLLSTIA
YLPDDNAALKVARSKAWTDFDADELAALADGSGAPQRLTLRLARETVDAFRSAWASEAAHLPMGDDVRQVVEAQLDRVPI
ARG
>Mature_402_residues
PGLDVWIGARRVGAITYLGGDRSVFAFDDAYADDPRRPTLSLVFKSAAGGLLREVRPTRARAHPYFSNLLPEGPLRDYLA
KRAGVNPTRELHLLAMLGDDLPGAVVLTVQEEAPLPRDAEPRRFYGGGEPTALRFSLAGVQLKFSAAEKAQGGLTIPAHG
VGGDWIVKLPSSRFNGVSENEFSMMTLAAAIGIEVPQVRLLSLEDIEGLPEDIGRLKGAAYAVSRFDRSPEGERIHIEDF
AQVFGVFPEAKYQRASYRNIGQVLWRETGEPGYAEFVRRLVFSALIGNADMHLKNWSLIYRDGRTPSLAPAYDLLSTIAY
LPDDNAALKVARSKAWTDFDADELAALADGSGAPQRLTLRLARETVDAFRSAWASEAAHLPMGDDVRQVVEAQLDRVPIA
RG

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=359, Percent_Identity=26.4623955431755, Blast_Score=92, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 44054; Mature: 43923

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGLDVWIGARRVGAITYLGGDRSVFAFDDAYADDPRRPTLSLVFKSAAGGLLREVRPTR
CCCCEEEECCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
ARAHPYFSNLLPEGPLRDYLAKRAGVNPTRELHLLAMLGDDLPGAVVLTVQEEAPLPRDA
HHCCCHHHHCCCCCHHHHHHHHHCCCCCCHHEEEEEEECCCCCCEEEEEEECCCCCCCCC
EPRRFYGGGEPTALRFSLAGVQLKFSAAEKAQGGLTIPAHGVGGDWIVKLPSSRFNGVSE
CCCCCCCCCCCCEEEEEEECEEEEECCHHHCCCCEEECCCCCCCCEEEECCCHHCCCCCC
NEFSMMTLAAAIGIEVPQVRLLSLEDIEGLPEDIGRLKGAAYAVSRFDRSPEGERIHIED
CCHHHHHHHHHHCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHH
FAQVFGVFPEAKYQRASYRNIGQVLWRETGEPGYAEFVRRLVFSALIGNADMHLKNWSLI
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCEEE
YRDGRTPSLAPAYDLLSTIAYLPDDNAALKVARSKAWTDFDADELAALADGSGAPQRLTL
EECCCCCCCCHHHHHHHHHHHCCCCCHHEEEEHHCCCCCCCHHHHHHHHCCCCCCHHHHH
RLARETVDAFRSAWASEAAHLPMGDDVRQVVEAQLDRVPIARG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PGLDVWIGARRVGAITYLGGDRSVFAFDDAYADDPRRPTLSLVFKSAAGGLLREVRPTR
CCCEEEECCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHH
ARAHPYFSNLLPEGPLRDYLAKRAGVNPTRELHLLAMLGDDLPGAVVLTVQEEAPLPRDA
HHCCCHHHHCCCCCHHHHHHHHHCCCCCCHHEEEEEEECCCCCCEEEEEEECCCCCCCCC
EPRRFYGGGEPTALRFSLAGVQLKFSAAEKAQGGLTIPAHGVGGDWIVKLPSSRFNGVSE
CCCCCCCCCCCCEEEEEEECEEEEECCHHHCCCCEEECCCCCCCCEEEECCCHHCCCCCC
NEFSMMTLAAAIGIEVPQVRLLSLEDIEGLPEDIGRLKGAAYAVSRFDRSPEGERIHIED
CCHHHHHHHHHHCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHH
FAQVFGVFPEAKYQRASYRNIGQVLWRETGEPGYAEFVRRLVFSALIGNADMHLKNWSLI
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCEEE
YRDGRTPSLAPAYDLLSTIAYLPDDNAALKVARSKAWTDFDADELAALADGSGAPQRLTL
EECCCCCCCCHHHHHHHHHHHCCCCCHHEEEEHHCCCCCCCHHHHHHHHCCCCCCHHHHH
RLARETVDAFRSAWASEAAHLPMGDDVRQVVEAQLDRVPIARG
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]