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The map label for this gene is yybO [H]

Identifier: 197105741

GI number: 197105741

Start: 2581978

End: 2583411

Strand: Direct

Name: yybO [H]

Synonym: PHZ_c2279

Alternate gene names: 197105741

Gene position: 2581978-2583411 (Clockwise)

Preceding gene: 197105740

Following gene: 197105753

Centisome position: 64.61

GC content: 70.22

Gene sequence:

>1434_bases
ATGAGTGCGACCACGACCGCCGCGGGTGCGGACGGCCACATCACCGGCTTCGGCTCCAAGCCCTACCGAAGCTACGTCCT
CAACGCGCTCCTGCTGATCTACATCCTGAACTTCGTGGACCGCGGCCTGCTGTCGGTGGTCGCGCCGCAGATGAAGCCCG
AGCTGGGAATCTCGGACACCGCGTTCGGCCTGCTGACCGGCTTCGGCTTCGCCCTGCTCTACACCTTCGTCGGCATCCCC
CTCGCCCAGTTCGCCGAGACGCGGCACCGGGTGTGGATCATGACCGTCTGCGTGGCCCTGTGGTCGCTGATGACGGCGCT
GTGCGGCCTGGCGGCGCCGATCACCATCGGCGGCATGGTCATCGGCGGCTTCTGGATCCTGCTGGCCTGCCGGGTCGGCG
TCGGCATCGGCGAGGCGGGCTGCACGCCGCCGGCCAACTCGCTGATCGCGGACTACTACCCGCCCCAGCGGCGCTCGACG
GCCCTCGGCTACTACGCCATGGGCGTGACCCTGGGCGGGCTGCTCGCCAATCTCATCGGCGGCCCGATCACCGACGCCTT
CGGCTGGCGCATGGCGTTCTTCGTGGTCGGCCTGCCGGGCCTGCTCGTCGCGGTGGTCTTCAAGATGACCGTCAAGGAGC
CGCCGCGCGGCTACACCGACCCGCCCGGCACGGTGCGCAAGGCCCGGCCCAAGTTCGCCGACGGCATGCGCGAACTCGCC
TCCAAGCCGTCGTTCTGGTGGATGACCGCGGGCGCGACCATCGCCTCCTTCTGCGGCTACGGCATCGCCTCGTTCCAGTC
GCTGTTCATCAACCGCTCGTTCGACCTCAGCGCGGGCCAGGCGGCGGTCTACATCAACGCGCCCGTGGCGCTGGCCGCCG
CGATCGGCACCCTGGCCACCGGCTGGCTGGCCGAGCGTCTGGGCAAGCGCTCGCCCAACGCCATCGCCTGGCTGCCCGGC
GTGGGCCTGACGCTCAGCGTGCCGTTCTACTTCGTGGCCTTCACGACCCAGAACCTGACGCTGTGCCTGATCGCCCTGAT
CATCGGCGGCGGCATCAAGTACGGCTACCTGGCGGCCCAGTACACCATCGGCCAGGGCGTGGTGACCGCCCAGGTCCGCG
CCGTCGCCACGGCCGTGCTGCTGTTCGTGATCAACCTGCTGGGCTACGGCCTCGGCCCGCTGTTCATCGGGGCGCTCAGC
GACATGCTGTTCCGGATGAAGGTGGCGAACCTCGGCGCCGCCGAGCTCACCCGCCAGGCCTGCGAAGGCGCCGCGCGGGC
GGCCCTGCCCGCCGCCGAGCAGGCGGTCTGCGCCGTCGCCCACCCCGAGAGCCTGCAGCACTCGATGCTGATCACCTCGG
CGCTCTACGCCGTCGCGGGCCTGTGCTTCTTCATGACCATGCGCTGGCTGAAGCGGGACATGGTCGCCCGGTAG

Upstream 100 bases:

>100_bases
CGGCGAACGCGCATACCGGACTTTCGGACTTTCCCGCTCCCCGTGAGGCCGCTACTTTCGCGCCCAAAGGCGAACACCGC
CAAAGGGGAAACGATCCAGC

Downstream 100 bases:

>100_bases
GCGGCCCCTCCTCCGGCGGAGGAATAGAGGGCTCCGGGGCGAGGCCGCCTCGGGGCCCTTCCTGCATCCGGCCTGCGCCC
GCTAGAGGAGGCCCGAGCCC

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MSATTTAAGADGHITGFGSKPYRSYVLNALLLIYILNFVDRGLLSVVAPQMKPELGISDTAFGLLTGFGFALLYTFVGIP
LAQFAETRHRVWIMTVCVALWSLMTALCGLAAPITIGGMVIGGFWILLACRVGVGIGEAGCTPPANSLIADYYPPQRRST
ALGYYAMGVTLGGLLANLIGGPITDAFGWRMAFFVVGLPGLLVAVVFKMTVKEPPRGYTDPPGTVRKARPKFADGMRELA
SKPSFWWMTAGATIASFCGYGIASFQSLFINRSFDLSAGQAAVYINAPVALAAAIGTLATGWLAERLGKRSPNAIAWLPG
VGLTLSVPFYFVAFTTQNLTLCLIALIIGGGIKYGYLAAQYTIGQGVVTAQVRAVATAVLLFVINLLGYGLGPLFIGALS
DMLFRMKVANLGAAELTRQACEGAARAALPAAEQAVCAVAHPESLQHSMLITSALYAVAGLCFFMTMRWLKRDMVAR

Sequences:

>Translated_477_residues
MSATTTAAGADGHITGFGSKPYRSYVLNALLLIYILNFVDRGLLSVVAPQMKPELGISDTAFGLLTGFGFALLYTFVGIP
LAQFAETRHRVWIMTVCVALWSLMTALCGLAAPITIGGMVIGGFWILLACRVGVGIGEAGCTPPANSLIADYYPPQRRST
ALGYYAMGVTLGGLLANLIGGPITDAFGWRMAFFVVGLPGLLVAVVFKMTVKEPPRGYTDPPGTVRKARPKFADGMRELA
SKPSFWWMTAGATIASFCGYGIASFQSLFINRSFDLSAGQAAVYINAPVALAAAIGTLATGWLAERLGKRSPNAIAWLPG
VGLTLSVPFYFVAFTTQNLTLCLIALIIGGGIKYGYLAAQYTIGQGVVTAQVRAVATAVLLFVINLLGYGLGPLFIGALS
DMLFRMKVANLGAAELTRQACEGAARAALPAAEQAVCAVAHPESLQHSMLITSALYAVAGLCFFMTMRWLKRDMVAR
>Mature_476_residues
SATTTAAGADGHITGFGSKPYRSYVLNALLLIYILNFVDRGLLSVVAPQMKPELGISDTAFGLLTGFGFALLYTFVGIPL
AQFAETRHRVWIMTVCVALWSLMTALCGLAAPITIGGMVIGGFWILLACRVGVGIGEAGCTPPANSLIADYYPPQRRSTA
LGYYAMGVTLGGLLANLIGGPITDAFGWRMAFFVVGLPGLLVAVVFKMTVKEPPRGYTDPPGTVRKARPKFADGMRELAS
KPSFWWMTAGATIASFCGYGIASFQSLFINRSFDLSAGQAAVYINAPVALAAAIGTLATGWLAERLGKRSPNAIAWLPGV
GLTLSVPFYFVAFTTQNLTLCLIALIIGGGIKYGYLAAQYTIGQGVVTAQVRAVATAVLLFVINLLGYGLGPLFIGALSD
MLFRMKVANLGAAELTRQACEGAARAALPAAEQAVCAVAHPESLQHSMLITSALYAVAGLCFFMTMRWLKRDMVAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=408, Percent_Identity=27.2058823529412, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI14042968, Length=408, Percent_Identity=27.2058823529412, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI215490100, Length=386, Percent_Identity=26.4248704663212, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI215490102, Length=401, Percent_Identity=26.1845386533666, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI185136021, Length=391, Percent_Identity=23.7851662404092, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI194239645, Length=477, Percent_Identity=23.6897274633124, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367379, Length=292, Percent_Identity=22.2602739726027, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789152, Length=217, Percent_Identity=24.4239631336406, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082320, Length=314, Percent_Identity=24.203821656051, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539092, Length=406, Percent_Identity=25.615763546798, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71992409, Length=405, Percent_Identity=24.4444444444444, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193209775, Length=491, Percent_Identity=23.8289205702648, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557872, Length=407, Percent_Identity=23.5872235872236, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24654041, Length=480, Percent_Identity=24.375, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24654037, Length=480, Percent_Identity=24.375, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24654039, Length=481, Percent_Identity=23.9085239085239, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17864456, Length=481, Percent_Identity=23.9085239085239, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24654044, Length=260, Percent_Identity=25.7692307692308, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640209, Length=159, Percent_Identity=25.7861635220126, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50475; Mature: 50344

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATTTAAGADGHITGFGSKPYRSYVLNALLLIYILNFVDRGLLSVVAPQMKPELGISDT
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AFGLLTGFGFALLYTFVGIPLAQFAETRHRVWIMTVCVALWSLMTALCGLAAPITIGGMV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGFWILLACRVGVGIGEAGCTPPANSLIADYYPPQRRSTALGYYAMGVTLGGLLANLIG
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GPITDAFGWRMAFFVVGLPGLLVAVVFKMTVKEPPRGYTDPPGTVRKARPKFADGMRELA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHH
SKPSFWWMTAGATIASFCGYGIASFQSLFINRSFDLSAGQAAVYINAPVALAAAIGTLAT
CCCCEEEEECCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHH
GWLAERLGKRSPNAIAWLPGVGLTLSVPFYFVAFTTQNLTLCLIALIIGGGIKYGYLAAQ
HHHHHHHCCCCCCCEEECCCCCCEEECCCEEEEEECCCHHHHHHHHHHCCCCHHHHEEEE
YTIGQGVVTAQVRAVATAVLLFVINLLGYGLGPLFIGALSDMLFRMKVANLGAAELTRQA
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CEGAARAALPAAEQAVCAVAHPESLQHSMLITSALYAVAGLCFFMTMRWLKRDMVAR
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SATTTAAGADGHITGFGSKPYRSYVLNALLLIYILNFVDRGLLSVVAPQMKPELGISDT
CCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
AFGLLTGFGFALLYTFVGIPLAQFAETRHRVWIMTVCVALWSLMTALCGLAAPITIGGMV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGGFWILLACRVGVGIGEAGCTPPANSLIADYYPPQRRSTALGYYAMGVTLGGLLANLIG
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GPITDAFGWRMAFFVVGLPGLLVAVVFKMTVKEPPRGYTDPPGTVRKARPKFADGMRELA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHH
SKPSFWWMTAGATIASFCGYGIASFQSLFINRSFDLSAGQAAVYINAPVALAAAIGTLAT
CCCCEEEEECCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHH
GWLAERLGKRSPNAIAWLPGVGLTLSVPFYFVAFTTQNLTLCLIALIIGGGIKYGYLAAQ
HHHHHHHCCCCCCCEEECCCCCCEEECCCEEEEEECCCHHHHHHHHHHCCCCHHHHEEEE
YTIGQGVVTAQVRAVATAVLLFVINLLGYGLGPLFIGALSDMLFRMKVANLGAAELTRQA
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CEGAARAALPAAEQAVCAVAHPESLQHSMLITSALYAVAGLCFFMTMRWLKRDMVAR
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]