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The map label for this gene is pckG [H]

Identifier: 197105694

GI number: 197105694

Start: 2524706

End: 2526556

Strand: Reverse

Name: pckG [H]

Synonym: PHZ_c2232

Alternate gene names: 197105694

Gene position: 2526556-2524706 (Counterclockwise)

Preceding gene: 197105701

Following gene: 197105690

Centisome position: 63.22

GC content: 68.45

Gene sequence:

>1851_bases
ATGAGCCAACCCACCGTCCCGGGACTTGCGCCCGCGCCGACGAAGCACGCCAAGCTGGTCCAATGGGTCGGCGAGATCGC
CGAGCTGACCCAGCCCGACCGCGTGGTCTGGTGCGACGGGTCGGAAGAGGAGTGGAACCGGCTGACCGAAGAGCTGGTCG
CCGCAGGCACCCTCAAGCGCCTCAATCCGGACAAGCGTCCGAACTCGTTCTACGCCGCCTCGGACCCGCGCGACGTCGCC
CGCGTCGAGAGCCGCACGTTCATCTGCTCGGAGAAGCAGGAGGACGCCGGTCCGACCAACAACTGGCTCGACCCCACCGA
GATGCGGGCCGACCTGAAGGACCTGTTCAAGGGCGTGATGCGCGGCCGCACCATGTACGTGGTGCCCTTCTGCATGGGCC
CGCTCGGCTCGAAGATCAGCGCCATCGGCGTCGAGATCACCGATTCCGCCTACGTGGCCGTATCGATGCGGATCATGACG
CGGATGGGCCAGGCCGCCCTCGACCAGCTCGGCGAGGACGGCTTTTTCGTTCCTGCGGTCCACTCGGTGGGCATGCCGCT
GGTCGACGGGGCCAAGGACGTCGCCTGGCCGTGCAACGAGATCAAGTACATCGTCCACTTCCCCGAGACCCGCGAGATCT
GGTCCTACGGCTCGGGCTACGGCGGCAACGCGCTGCTGGGCAAGAAGTGCTTCGCGCTGCGCATCGCCTCGGTCATGGCC
CGTGACGAGGGCTGGTTCGCCGAGCACATGCTGATCCTGAAGCTGACCTCGCCCGAGGGGCAGGTCCGCTACATCGCCGC
GGCCTTCCCCAGCGCCTGCGGCAAGACCAACATGGCCATGCTGCAGCCGACGCTGGCCGGCTGGAAGGCCGAGACGATCG
GCGACGACATCTGCTGGATGCGCTTCGGCGACGACGGACGCCTCTATGCGGTCAACCCCGAGGCGGGCTTCTTCGGCGTG
GCGCCGGGCACGGGCGTCAACACCAACCAGAACGCCATCGCCACGCTGCATTCGAACTGCATCTTCACCAACGTCGCGCT
CACCGAGGACGGCGACGTCTGGTGGGAAGGCCTGACCGACGAGCCGCCGGCGCGCCTGATCGACTGGAAGGGCCGTCCGT
GGACGCCCGACAGCGACGAGCCCGCCGCGCACCCGAACGCCCGCTTCACGGTTCCGGCCTCGCAGTGCCCGGTCGCCGCG
CCCGAGTGGGAGGACCCGGCGGGCGTGCCGATCTCGGCCATCCTGTTCGGCGGCCGTCGGGCGTCGGCCGTGCCGCTGGT
CACCGAGGCGCGCGACTGGACCCACGGCGTATTCATGGCCTCGAACGTCGCCTCGGAAGGCACCGCCGCCGCCGAGAACA
AGATCGGCGAACTGCGCCGCGATCCCTTCGCCATGCTGCCCTTCTGCGGCTACAACATGGGCGACTACTTCGGCCACTGG
CTGGCCATGGGCGAGCAGGCCGATCCGGCCAAGCTGCCGCGGATCTACTTCGTGAACTGGTTCCGCAAGGACGAGCGGGG
CAAGTTCGTCTGGCCGGGCTTCGGCGACAACTCGCGGGTCCTGAAGTGGATCGTCGAGCGGCTGGAGGGCAAGGCCGACG
CCGTGGACACCCCGATCGGTCGCGTGCCGTCGAAGACGAGCCTGGACCTGTCGGGTCTGACCCTCAGCGACCAGCAGCTC
GACCTGCTGCTGACGGTGGATCCCGCGATCTGGGGCCAGGAAGCGGCCCTCATCCCCGATTTCTACCAGCGGTTCGGCGA
GCATTTGCCGAAGGCGCTGTGGGGCGAGTACGAGGCGCTGGTGAAGCGCCTCGAGGAAGCTGCGCCCAAGCAGGTCGTCG
CCGCCGAATAG

Upstream 100 bases:

>100_bases
TAGGCAGACGCGCTTTCCGCCGTTAAGGAGTTGCTCACGTGTAAGGAGCGTGCGGGGCGTCTGCCGCACGCGCCGAGTTG
GGGCCAGGGAGTTTTCGTCT

Downstream 100 bases:

>100_bases
GCGCGGCGGCCACCCTCCGGACGACGAAGGCCGCGGGTCACCCCGCGGCCTTTTCGTTTCAGGCCTTCCCGTCGCCGGGC
GGCTCGACCTGGCTGGAGAA

Product: phosphoenolpyruvate carboxykinase

Products: NA

Alternate protein names: PEP carboxykinase; PEPCK; Phosphoenolpyruvate carboxylase [H]

Number of amino acids: Translated: 616; Mature: 615

Protein sequence:

>616_residues
MSQPTVPGLAPAPTKHAKLVQWVGEIAELTQPDRVVWCDGSEEEWNRLTEELVAAGTLKRLNPDKRPNSFYAASDPRDVA
RVESRTFICSEKQEDAGPTNNWLDPTEMRADLKDLFKGVMRGRTMYVVPFCMGPLGSKISAIGVEITDSAYVAVSMRIMT
RMGQAALDQLGEDGFFVPAVHSVGMPLVDGAKDVAWPCNEIKYIVHFPETREIWSYGSGYGGNALLGKKCFALRIASVMA
RDEGWFAEHMLILKLTSPEGQVRYIAAAFPSACGKTNMAMLQPTLAGWKAETIGDDICWMRFGDDGRLYAVNPEAGFFGV
APGTGVNTNQNAIATLHSNCIFTNVALTEDGDVWWEGLTDEPPARLIDWKGRPWTPDSDEPAAHPNARFTVPASQCPVAA
PEWEDPAGVPISAILFGGRRASAVPLVTEARDWTHGVFMASNVASEGTAAAENKIGELRRDPFAMLPFCGYNMGDYFGHW
LAMGEQADPAKLPRIYFVNWFRKDERGKFVWPGFGDNSRVLKWIVERLEGKADAVDTPIGRVPSKTSLDLSGLTLSDQQL
DLLLTVDPAIWGQEAALIPDFYQRFGEHLPKALWGEYEALVKRLEEAAPKQVVAAE

Sequences:

>Translated_616_residues
MSQPTVPGLAPAPTKHAKLVQWVGEIAELTQPDRVVWCDGSEEEWNRLTEELVAAGTLKRLNPDKRPNSFYAASDPRDVA
RVESRTFICSEKQEDAGPTNNWLDPTEMRADLKDLFKGVMRGRTMYVVPFCMGPLGSKISAIGVEITDSAYVAVSMRIMT
RMGQAALDQLGEDGFFVPAVHSVGMPLVDGAKDVAWPCNEIKYIVHFPETREIWSYGSGYGGNALLGKKCFALRIASVMA
RDEGWFAEHMLILKLTSPEGQVRYIAAAFPSACGKTNMAMLQPTLAGWKAETIGDDICWMRFGDDGRLYAVNPEAGFFGV
APGTGVNTNQNAIATLHSNCIFTNVALTEDGDVWWEGLTDEPPARLIDWKGRPWTPDSDEPAAHPNARFTVPASQCPVAA
PEWEDPAGVPISAILFGGRRASAVPLVTEARDWTHGVFMASNVASEGTAAAENKIGELRRDPFAMLPFCGYNMGDYFGHW
LAMGEQADPAKLPRIYFVNWFRKDERGKFVWPGFGDNSRVLKWIVERLEGKADAVDTPIGRVPSKTSLDLSGLTLSDQQL
DLLLTVDPAIWGQEAALIPDFYQRFGEHLPKALWGEYEALVKRLEEAAPKQVVAAE
>Mature_615_residues
SQPTVPGLAPAPTKHAKLVQWVGEIAELTQPDRVVWCDGSEEEWNRLTEELVAAGTLKRLNPDKRPNSFYAASDPRDVAR
VESRTFICSEKQEDAGPTNNWLDPTEMRADLKDLFKGVMRGRTMYVVPFCMGPLGSKISAIGVEITDSAYVAVSMRIMTR
MGQAALDQLGEDGFFVPAVHSVGMPLVDGAKDVAWPCNEIKYIVHFPETREIWSYGSGYGGNALLGKKCFALRIASVMAR
DEGWFAEHMLILKLTSPEGQVRYIAAAFPSACGKTNMAMLQPTLAGWKAETIGDDICWMRFGDDGRLYAVNPEAGFFGVA
PGTGVNTNQNAIATLHSNCIFTNVALTEDGDVWWEGLTDEPPARLIDWKGRPWTPDSDEPAAHPNARFTVPASQCPVAAP
EWEDPAGVPISAILFGGRRASAVPLVTEARDWTHGVFMASNVASEGTAAAENKIGELRRDPFAMLPFCGYNMGDYFGHWL
AMGEQADPAKLPRIYFVNWFRKDERGKFVWPGFGDNSRVLKWIVERLEGKADAVDTPIGRVPSKTSLDLSGLTLSDQQLD
LLLTVDPAIWGQEAALIPDFYQRFGEHLPKALWGEYEALVKRLEEAAPKQVVAAE

Specific function: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle [H]

COG id: COG1274

COG function: function code C; Phosphoenolpyruvate carboxykinase (GTP)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family [H]

Homologues:

Organism=Homo sapiens, GI66346721, Length=599, Percent_Identity=53.9232053422371, Blast_Score=624, Evalue=1e-179,
Organism=Homo sapiens, GI187281517, Length=594, Percent_Identity=52.8619528619529, Blast_Score=616, Evalue=1e-176,
Organism=Homo sapiens, GI66346723, Length=368, Percent_Identity=54.8913043478261, Blast_Score=394, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71989645, Length=605, Percent_Identity=50.5785123966942, Blast_Score=597, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71989658, Length=605, Percent_Identity=50.5785123966942, Blast_Score=595, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71989653, Length=591, Percent_Identity=50.761421319797, Blast_Score=584, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI17555492, Length=614, Percent_Identity=47.8827361563518, Blast_Score=553, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI32564411, Length=541, Percent_Identity=50.6469500924214, Blast_Score=534, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI32564407, Length=522, Percent_Identity=50.5747126436782, Blast_Score=507, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI71989649, Length=545, Percent_Identity=48.0733944954128, Blast_Score=502, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI32564409, Length=368, Percent_Identity=48.6413043478261, Blast_Score=342, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17540956, Length=523, Percent_Identity=25.2390057361377, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24655085, Length=597, Percent_Identity=52.5963149078727, Blast_Score=631, Evalue=0.0,
Organism=Drosophila melanogaster, GI24655082, Length=600, Percent_Identity=52.3333333333333, Blast_Score=609, Evalue=1e-174,
Organism=Drosophila melanogaster, GI161077226, Length=556, Percent_Identity=53.4172661870504, Blast_Score=584, Evalue=1e-167,
Organism=Drosophila melanogaster, GI24655088, Length=503, Percent_Identity=54.0755467196819, Blast_Score=561, Evalue=1e-160,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018091
- InterPro:   IPR013035
- InterPro:   IPR008209
- InterPro:   IPR008210 [H]

Pfam domain/function: PF00821 PEPCK [H]

EC number: =4.1.1.32 [H]

Molecular weight: Translated: 67787; Mature: 67655

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00505 PEPCK_GTP ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPTVPGLAPAPTKHAKLVQWVGEIAELTQPDRVVWCDGSEEEWNRLTEELVAAGTLKR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
LNPDKRPNSFYAASDPRDVARVESRTFICSEKQEDAGPTNNWLDPTEMRADLKDLFKGVM
CCCCCCCCCEECCCCCHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RGRTMYVVPFCMGPLGSKISAIGVEITDSAYVAVSMRIMTRMGQAALDQLGEDGFFVPAV
CCCEEEEEEEECCCCCCCEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEHHH
HSVGMPLVDGAKDVAWPCNEIKYIVHFPETREIWSYGSGYGGNALLGKKCFALRIASVMA
HHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RDEGWFAEHMLILKLTSPEGQVRYIAAAFPSACGKTNMAMLQPTLAGWKAETIGDDICWM
CCCCCCEEEEEEEEEECCCCCEEEEEECCCHHCCCCCHHHCCHHHCCCCCCCCCCCEEEE
RFGDDGRLYAVNPEAGFFGVAPGTGVNTNQNAIATLHSNCIFTNVALTEDGDVWWEGLTD
EECCCCEEEEECCCCCEEECCCCCCCCCCCCEEEEEECCEEEEEEEEECCCCEEECCCCC
EPPARLIDWKGRPWTPDSDEPAAHPNARFTVPASQCPVAAPEWEDPAGVPISAILFGGRR
CCCCCEEECCCCCCCCCCCCCCCCCCCEEEECHHHCCCCCCCCCCCCCCCEEEEEECCCC
ASAVPLVTEARDWTHGVFMASNVASEGTAAAENKIGELRRDPFAMLPFCGYNMGDYFGHW
CCCCCEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHH
LAMGEQADPAKLPRIYFVNWFRKDERGKFVWPGFGDNSRVLKWIVERLEGKADAVDTPIG
HHCCCCCCCCCCCEEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
RVPSKTSLDLSGLTLSDQQLDLLLTVDPAIWGQEAALIPDFYQRFGEHLPKALWGEYEAL
CCCCCCCCEECCEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VKRLEEAAPKQVVAAE
HHHHHHHCCCCEECCC
>Mature Secondary Structure 
SQPTVPGLAPAPTKHAKLVQWVGEIAELTQPDRVVWCDGSEEEWNRLTEELVAAGTLKR
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
LNPDKRPNSFYAASDPRDVARVESRTFICSEKQEDAGPTNNWLDPTEMRADLKDLFKGVM
CCCCCCCCCEECCCCCHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RGRTMYVVPFCMGPLGSKISAIGVEITDSAYVAVSMRIMTRMGQAALDQLGEDGFFVPAV
CCCEEEEEEEECCCCCCCEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEHHH
HSVGMPLVDGAKDVAWPCNEIKYIVHFPETREIWSYGSGYGGNALLGKKCFALRIASVMA
HHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
RDEGWFAEHMLILKLTSPEGQVRYIAAAFPSACGKTNMAMLQPTLAGWKAETIGDDICWM
CCCCCCEEEEEEEEEECCCCCEEEEEECCCHHCCCCCHHHCCHHHCCCCCCCCCCCEEEE
RFGDDGRLYAVNPEAGFFGVAPGTGVNTNQNAIATLHSNCIFTNVALTEDGDVWWEGLTD
EECCCCEEEEECCCCCEEECCCCCCCCCCCCEEEEEECCEEEEEEEEECCCCEEECCCCC
EPPARLIDWKGRPWTPDSDEPAAHPNARFTVPASQCPVAAPEWEDPAGVPISAILFGGRR
CCCCCEEECCCCCCCCCCCCCCCCCCCEEEECHHHCCCCCCCCCCCCCCCEEEEEECCCC
ASAVPLVTEARDWTHGVFMASNVASEGTAAAENKIGELRRDPFAMLPFCGYNMGDYFGHW
CCCCCEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHH
LAMGEQADPAKLPRIYFVNWFRKDERGKFVWPGFGDNSRVLKWIVERLEGKADAVDTPIG
HHCCCCCCCCCCCEEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
RVPSKTSLDLSGLTLSDQQLDLLLTVDPAIWGQEAALIPDFYQRFGEHLPKALWGEYEAL
CCCCCCCCEECCEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VKRLEEAAPKQVVAAE
HHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA