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The map label for this gene is murA [H]

Identifier: 197105664

GI number: 197105664

Start: 2485552

End: 2486850

Strand: Reverse

Name: murA [H]

Synonym: PHZ_c2201

Alternate gene names: 197105664

Gene position: 2486850-2485552 (Counterclockwise)

Preceding gene: 197105667

Following gene: 197105663

Centisome position: 62.23

GC content: 68.75

Gene sequence:

>1299_bases
TTGCGATTGGACCGCATCGCCATTGTCGGCGGCGCGCGGCTGAAGGGGGAGATCCCGATCAGCGGCGCCAAGAACTCCGC
GATCAAGCTGATGGCGGCGAGTCTCCTCACCGAGGAGCCGCTGCGGCTGACCAACATGCCGAGGCTCGCCGACACGCGGT
TTCTGGGCAAGCTGCTGCAGAGGCTCGGCGCCGAGGTCGTGGAGTCCGACGGGCCGGAGGGATCCGAGACCCTGCTCACG
ACCCGCGAGATCGTCAGTGGGTTCGCGCCCTACGACCTGGTCCGCCAGATGCGGGCCTCGTTCAACGTGCTGGGGCCGCT
TTTGGCGCGCTCGGGGCAGGCCAAGGTGTCGCTACCCGGCGGATGCACGATCGGCGCGCGGCCGGTGGATCTGCACTTGC
AGGCGCTCGAGGCGCTCGGCGCTCGGATCGACCTGCACGAAGGCTATGTCTACGCCCAGGCCCCCCGCGGGCTTAGGGGC
GCCGAGATCGAGTTTCCCTTCGTATCCGTGGGCGCCACGGAGCACACACTGCTCGCGGCGGTGCTGGCTAAAGGCGATAC
CGAGATCCGCAACGCGGCGTGCGAGCCCGAGATCGAGGATCTCGCCGACTGCCTCAACAAGATGGGGGCCAAGGTTTCCG
GCGCGGGCACCTCGGTGATCCAGATCGAAGGCGTCGCGCGGTTGTCGGGAGCGACGCACGCGGTGCTCGCCGACCGAATC
GAGACCGGCACCTATGCGCTGGCGGCGGCGATGGCCGGCGGCGAGGTGCGCCTGACCCGCACCCGGAGCGACTTCATTCA
GGCGCTGGTCGACAAGATGGTCGAGGCCGGCGTCGAGGTGACGGCCCACAACGACGGGCTGACCGTGAAGCGGAACGGCG
GACGGCTGAAGGCCGTGGACGTGGAGACCGATCCCTATCCGGGCTTCGCCACGGACTTGCAGGCGCAGTTCATGGCGCTG
ATGACGCTGGCCGAAGGCGAAAGCGTCATCAAGGAGACCATCTTCGAGAACCGGTTCATGCATGCGCCCGAGCTGCGACG
GCTCGGCGCCGACATCACCGTCCATGGCGGCGAGGCGCGCGTGCGGGGCGTCGAGGCTCTCGAAGGCGCCCAGGTGATGG
CCACGGACCTGCGCGCGTCGGTGAGCCTGGTGATCGCCGGCCTTGCGGCCCGAGGCGAAACGGTCGTCAACCGCGTTTAC
CACCTCGACCGCGGTTTCGAGCGCCTGGAAGAGAAGCTTGGCGCGTGCGGGGCGCAGATCCGCCGCATCAAGGGCGACGG
AACGGGCGAGGAGGACTGA

Upstream 100 bases:

>100_bases
GCACCGGACGTCGACTGACGGCCATTGCGCCAGCCGGCGCGCACGTTAGATATCGCGAAAGGCGTCCGCGGCTCCGCGCG
GCCCCACGTGCTGCAAAGGA

Downstream 100 bases:

>100_bases
GACGCATGGGCGAGACCGGCCCCCTGAGACTTCTGGCGCAGGACGCCGACGATCTGGCGGTGCTGTCCGCCGCGCTCCAA
GACGCGGTCGGGAAGGTTGG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRLDRIAIVGGARLKGEIPISGAKNSAIKLMAASLLTEEPLRLTNMPRLADTRFLGKLLQRLGAEVVESDGPEGSETLLT
TREIVSGFAPYDLVRQMRASFNVLGPLLARSGQAKVSLPGGCTIGARPVDLHLQALEALGARIDLHEGYVYAQAPRGLRG
AEIEFPFVSVGATEHTLLAAVLAKGDTEIRNAACEPEIEDLADCLNKMGAKVSGAGTSVIQIEGVARLSGATHAVLADRI
ETGTYALAAAMAGGEVRLTRTRSDFIQALVDKMVEAGVEVTAHNDGLTVKRNGGRLKAVDVETDPYPGFATDLQAQFMAL
MTLAEGESVIKETIFENRFMHAPELRRLGADITVHGGEARVRGVEALEGAQVMATDLRASVSLVIAGLAARGETVVNRVY
HLDRGFERLEEKLGACGAQIRRIKGDGTGEED

Sequences:

>Translated_432_residues
MRLDRIAIVGGARLKGEIPISGAKNSAIKLMAASLLTEEPLRLTNMPRLADTRFLGKLLQRLGAEVVESDGPEGSETLLT
TREIVSGFAPYDLVRQMRASFNVLGPLLARSGQAKVSLPGGCTIGARPVDLHLQALEALGARIDLHEGYVYAQAPRGLRG
AEIEFPFVSVGATEHTLLAAVLAKGDTEIRNAACEPEIEDLADCLNKMGAKVSGAGTSVIQIEGVARLSGATHAVLADRI
ETGTYALAAAMAGGEVRLTRTRSDFIQALVDKMVEAGVEVTAHNDGLTVKRNGGRLKAVDVETDPYPGFATDLQAQFMAL
MTLAEGESVIKETIFENRFMHAPELRRLGADITVHGGEARVRGVEALEGAQVMATDLRASVSLVIAGLAARGETVVNRVY
HLDRGFERLEEKLGACGAQIRRIKGDGTGEED
>Mature_432_residues
MRLDRIAIVGGARLKGEIPISGAKNSAIKLMAASLLTEEPLRLTNMPRLADTRFLGKLLQRLGAEVVESDGPEGSETLLT
TREIVSGFAPYDLVRQMRASFNVLGPLLARSGQAKVSLPGGCTIGARPVDLHLQALEALGARIDLHEGYVYAQAPRGLRG
AEIEFPFVSVGATEHTLLAAVLAKGDTEIRNAACEPEIEDLADCLNKMGAKVSGAGTSVIQIEGVARLSGATHAVLADRI
ETGTYALAAAMAGGEVRLTRTRSDFIQALVDKMVEAGVEVTAHNDGLTVKRNGGRLKAVDVETDPYPGFATDLQAQFMAL
MTLAEGESVIKETIFENRFMHAPELRRLGADITVHGGEARVRGVEALEGAQVMATDLRASVSLVIAGLAARGETVVNRVY
HLDRGFERLEEKLGACGAQIRRIKGDGTGEED

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=424, Percent_Identity=51.8867924528302, Blast_Score=410, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45954; Mature: 45954

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDRIAIVGGARLKGEIPISGAKNSAIKLMAASLLTEEPLRLTNMPRLADTRFLGKLLQ
CCCCEEEEEECCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHH
RLGAEVVESDGPEGSETLLTTREIVSGFAPYDLVRQMRASFNVLGPLLARSGQAKVSLPG
HHCHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GCTIGARPVDLHLQALEALGARIDLHEGYVYAQAPRGLRGAEIEFPFVSVGATEHTLLAA
CCEECCCCHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCEEECCEEECCCCHHHHHHH
VLAKGDTEIRNAACEPEIEDLADCLNKMGAKVSGAGTSVIQIEGVARLSGATHAVLADRI
HHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCEEEEEECHHHHCCCHHHHHHHHH
ETGTYALAAAMAGGEVRLTRTRSDFIQALVDKMVEAGVEVTAHNDGLTVKRNGGRLKAVD
CCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEEEEEE
VETDPYPGFATDLQAQFMALMTLAEGESVIKETIFENRFMHAPELRRLGADITVHGGEAR
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCHH
VRGVEALEGAQVMATDLRASVSLVIAGLAARGETVVNRVYHLDRGFERLEEKLGACGAQI
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RRIKGDGTGEED
EEECCCCCCCCC
>Mature Secondary Structure
MRLDRIAIVGGARLKGEIPISGAKNSAIKLMAASLLTEEPLRLTNMPRLADTRFLGKLLQ
CCCCEEEEEECCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHH
RLGAEVVESDGPEGSETLLTTREIVSGFAPYDLVRQMRASFNVLGPLLARSGQAKVSLPG
HHCHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GCTIGARPVDLHLQALEALGARIDLHEGYVYAQAPRGLRGAEIEFPFVSVGATEHTLLAA
CCEECCCCHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCEEECCEEECCCCHHHHHHH
VLAKGDTEIRNAACEPEIEDLADCLNKMGAKVSGAGTSVIQIEGVARLSGATHAVLADRI
HHHCCCHHHHHCCCCCCHHHHHHHHHHHCCEECCCCCEEEEEECHHHHCCCHHHHHHHHH
ETGTYALAAAMAGGEVRLTRTRSDFIQALVDKMVEAGVEVTAHNDGLTVKRNGGRLKAVD
CCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCEEEEEE
VETDPYPGFATDLQAQFMALMTLAEGESVIKETIFENRFMHAPELRRLGADITVHGGEAR
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCHH
VRGVEALEGAQVMATDLRASVSLVIAGLAARGETVVNRVYHLDRGFERLEEKLGACGAQI
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RRIKGDGTGEED
EEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA