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The map label for this gene is 197105616

Identifier: 197105616

GI number: 197105616

Start: 2423321

End: 2425048

Strand: Reverse

Name: 197105616

Synonym: PHZ_c2153

Alternate gene names: NA

Gene position: 2425048-2423321 (Counterclockwise)

Preceding gene: 197105617

Following gene: 197105615

Centisome position: 60.68

GC content: 71.3

Gene sequence:

>1728_bases
ATGGCCAACCTGAACAACCGCGCGCGGGCCGAGCGAACCTACGACGCCATCGTGGTCGGCAGCGGGATCACCGGCGGCTG
GGCGGCCAAGGAGCTGACCGAGCGGGGGCTGAAGACCCTGGTGCTGGAGCGCGGCGGGCCGGTGCGGCACGTCCTCGACT
ACCCGACCGCCGCCGCCGATCCCTGGGACGCCCAATATCCCAGGGGCCGTCTGCCCGCCGCCGAGCTGAGGGCGAAGTAC
CCGGTGCAGCAGCGCACGGGCTACGCGCTCACCGAGCACACCCGGCATTTCTTCGTCCGGGACGACGAGAACCCCTACGC
CGAGACCCAGCGGTTCGACTGGATCCGCGGCTATCACGTCGGCGGCCGCTCGCTGACCTGGGGCCGCCAGAGCTACCGCT
GGTCCGACCTCGACTTCGAGGCCAATGCGCGCGAGGGGATCGCGGTCGACTGGCCCATCCGCTACGCCGACCTCGCCCCC
TGGTACGACCATGTGGAGCGGTTCATCGGGGTCTCGGGCCAGGCCGAGGGCCTGCCGCAGCTTCCGGACGGCGTCTTCCA
GCCGCCGATGGAGATGAACTGCGTCGAGAAGGCCTTCAAGGAACGGTCCGAGGCGCGCTTTCCCGACCGGCGGATCACCA
TCGGCCGCACGGCGCACCTGACGGCGCCCACGCAGGAACAGCTCGCGCTCGGGCGCGGCCAGTGCCAGTACCGCAACCTC
TGCATCCGCGGCTGCCCGTTCGGGGCCTACTTCAGCTCCAATGCGGCGACGCTGGTGGCGGCCGAGCGGACTGGCCGCCT
GCAGGTGCGTCCGAATTCCATCGTCACCACCCTGGTCTACGACGAGCGGCGGCAGCGGGCCTCCGGCGTGCGGATCCTCG
ACGCCGAGACGGGCCAGGAGGAGGAGTTCTACGCGGGCGTCGTCTTCCTCTGCGCCTCGGCGGTGGCGAGCGCCTGGATC
CTGCTGAACTCGGCCAGCGCGCGCTTCCCGAACGGCTTCGGCAACGGCTCGGACCAGGTCGGCCGCAACCTCATGGACCA
TCACCTGGGGGTCGGCGCCTCGGCCTTGGTCGACGGGTTCGAGGACAGGTACTATTCGGGACGGCGGCCGAACGGCCTCT
ACATCCCGCGCTTCCGCAATCTCGGCGACGCCGCCAGCCGTCGGCCGGACTACCTGCGCGGCTTCGGCTACCAGGGAGGC
GCCGGGCGGCTCGGCTGGGACCGCCCGACGGAAGGCTTCGGCGCCGAGCGCAAGCAGGCTCTCAGCCAGCCGGGCCCGTG
GGGCGTGCGGCTGGGGGGCTTCGGCGAGATCCTGCCCTACGCCGACAACCGCATGACCCTGAACCGCGAGGTGAAGGACC
GCTACGGCCTGCCGACGCTGAGCTTCGACGCCGCGATCGGCGACAACGAGGCGGCCATGCGCAAGGACATGGCGGCGGCC
GCCGCCGAGATGCTGGAGGCCGCCGGCTTCAAGAACGTGGCGCCTTACGAGGGCGACTACGCCCTGGGCCTGGGCATCCA
CGAGATGGGCACGGCCCGCATGGGGCGCGATCCGACGACCTCGGTGCTCAACGCCCGCAACCAGCTTCACGAGTGCCCGA
ACGTCTTCGTCACCGACGGGGCGGCCATGACCTCGTCGGCCTGCGTGAACCCGTCGCTGACCTACATGGCGCTGACCGCT
CGGGCCGCCGCGTACGCGGCCGAGGCGGGCCGGAAGGGAGACCTCTGA

Upstream 100 bases:

>100_bases
CACATCATCCGCGTGACCGAGCGGGCGTTCGACGACTTCGCCGGCGCGGGCACGGACGCGGCCGCCAACCGGCGACTTCT
TGGGCTGGGGGACGCTTGAG

Downstream 100 bases:

>100_bases
TGGCGACCCCGATCCTCAACCGCCGCGAAGCGTTCGCCGGCGCGCTGGCCGCGCTCTGGATCGCGCCGGTGGTGGCCCAC
GCGCAGGCCGCCGCCGCGGT

Product: choline dehydrogenase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MANLNNRARAERTYDAIVVGSGITGGWAAKELTERGLKTLVLERGGPVRHVLDYPTAAADPWDAQYPRGRLPAAELRAKY
PVQQRTGYALTEHTRHFFVRDDENPYAETQRFDWIRGYHVGGRSLTWGRQSYRWSDLDFEANAREGIAVDWPIRYADLAP
WYDHVERFIGVSGQAEGLPQLPDGVFQPPMEMNCVEKAFKERSEARFPDRRITIGRTAHLTAPTQEQLALGRGQCQYRNL
CIRGCPFGAYFSSNAATLVAAERTGRLQVRPNSIVTTLVYDERRQRASGVRILDAETGQEEEFYAGVVFLCASAVASAWI
LLNSASARFPNGFGNGSDQVGRNLMDHHLGVGASALVDGFEDRYYSGRRPNGLYIPRFRNLGDAASRRPDYLRGFGYQGG
AGRLGWDRPTEGFGAERKQALSQPGPWGVRLGGFGEILPYADNRMTLNREVKDRYGLPTLSFDAAIGDNEAAMRKDMAAA
AAEMLEAAGFKNVAPYEGDYALGLGIHEMGTARMGRDPTTSVLNARNQLHECPNVFVTDGAAMTSSACVNPSLTYMALTA
RAAAYAAEAGRKGDL

Sequences:

>Translated_575_residues
MANLNNRARAERTYDAIVVGSGITGGWAAKELTERGLKTLVLERGGPVRHVLDYPTAAADPWDAQYPRGRLPAAELRAKY
PVQQRTGYALTEHTRHFFVRDDENPYAETQRFDWIRGYHVGGRSLTWGRQSYRWSDLDFEANAREGIAVDWPIRYADLAP
WYDHVERFIGVSGQAEGLPQLPDGVFQPPMEMNCVEKAFKERSEARFPDRRITIGRTAHLTAPTQEQLALGRGQCQYRNL
CIRGCPFGAYFSSNAATLVAAERTGRLQVRPNSIVTTLVYDERRQRASGVRILDAETGQEEEFYAGVVFLCASAVASAWI
LLNSASARFPNGFGNGSDQVGRNLMDHHLGVGASALVDGFEDRYYSGRRPNGLYIPRFRNLGDAASRRPDYLRGFGYQGG
AGRLGWDRPTEGFGAERKQALSQPGPWGVRLGGFGEILPYADNRMTLNREVKDRYGLPTLSFDAAIGDNEAAMRKDMAAA
AAEMLEAAGFKNVAPYEGDYALGLGIHEMGTARMGRDPTTSVLNARNQLHECPNVFVTDGAAMTSSACVNPSLTYMALTA
RAAAYAAEAGRKGDL
>Mature_574_residues
ANLNNRARAERTYDAIVVGSGITGGWAAKELTERGLKTLVLERGGPVRHVLDYPTAAADPWDAQYPRGRLPAAELRAKYP
VQQRTGYALTEHTRHFFVRDDENPYAETQRFDWIRGYHVGGRSLTWGRQSYRWSDLDFEANAREGIAVDWPIRYADLAPW
YDHVERFIGVSGQAEGLPQLPDGVFQPPMEMNCVEKAFKERSEARFPDRRITIGRTAHLTAPTQEQLALGRGQCQYRNLC
IRGCPFGAYFSSNAATLVAAERTGRLQVRPNSIVTTLVYDERRQRASGVRILDAETGQEEEFYAGVVFLCASAVASAWIL
LNSASARFPNGFGNGSDQVGRNLMDHHLGVGASALVDGFEDRYYSGRRPNGLYIPRFRNLGDAASRRPDYLRGFGYQGGA
GRLGWDRPTEGFGAERKQALSQPGPWGVRLGGFGEILPYADNRMTLNREVKDRYGLPTLSFDAAIGDNEAAMRKDMAAAA
AEMLEAAGFKNVAPYEGDYALGLGIHEMGTARMGRDPTTSVLNARNQLHECPNVFVTDGAAMTSSACVNPSLTYMALTAR
AAAYAAEAGRKGDL

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 63360; Mature: 63228

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLNNRARAERTYDAIVVGSGITGGWAAKELTERGLKTLVLERGGPVRHVLDYPTAAAD
CCCCCCHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHEEEHHCCCCCHHHHCCCCCCCC
PWDAQYPRGRLPAAELRAKYPVQQRTGYALTEHTRHFFVRDDENPYAETQRFDWIRGYHV
CCCCCCCCCCCCHHHHHHCCCHHHCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHCEEC
GGRSLTWGRQSYRWSDLDFEANAREGIAVDWPIRYADLAPWYDHVERFIGVSGQAEGLPQ
CCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCHHHHHHHHHHCCCCCCCCCCC
LPDGVFQPPMEMNCVEKAFKERSEARFPDRRITIGRTAHLTAPTQEQLALGRGQCQYRNL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEEECCCCHHHHHHCCCCCHHHCE
CIRGCPFGAYFSSNAATLVAAERTGRLQVRPNSIVTTLVYDERRQRASGVRILDAETGQE
EEECCCCCCEECCCCEEEEEECCCCEEEECCCCEEEEEEEHHHHHHHCCCEEEECCCCCC
EEFYAGVVFLCASAVASAWILLNSASARFPNGFGNGSDQVGRNLMDHHLGVGASALVDGF
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
EDRYYSGRRPNGLYIPRFRNLGDAASRRPDYLRGFGYQGGAGRLGWDRPTEGFGAERKQA
HHHHCCCCCCCCEECCCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
LSQPGPWGVRLGGFGEILPYADNRMTLNREVKDRYGLPTLSFDAAIGDNEAAMRKDMAAA
HCCCCCCEEEECCCCCCCCCCCCCEEECCHHHHHCCCCCEEECCCCCCCHHHHHHHHHHH
AAEMLEAAGFKNVAPYEGDYALGLGIHEMGTARMGRDPTTSVLNARNQLHECPNVFVTDG
HHHHHHHCCCCCCCCCCCCEEEECCHHHHCCHHCCCCCHHHHHHHHHHHHHCCCEEEECC
AAMTSSACVNPSLTYMALTARAAAYAAEAGRKGDL
CHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANLNNRARAERTYDAIVVGSGITGGWAAKELTERGLKTLVLERGGPVRHVLDYPTAAAD
CCCCCHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHEEEHHCCCCCHHHHCCCCCCCC
PWDAQYPRGRLPAAELRAKYPVQQRTGYALTEHTRHFFVRDDENPYAETQRFDWIRGYHV
CCCCCCCCCCCCHHHHHHCCCHHHCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHCEEC
GGRSLTWGRQSYRWSDLDFEANAREGIAVDWPIRYADLAPWYDHVERFIGVSGQAEGLPQ
CCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCHHHHHHHHHHCCCCCCCCCCC
LPDGVFQPPMEMNCVEKAFKERSEARFPDRRITIGRTAHLTAPTQEQLALGRGQCQYRNL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEEECCCCHHHHHHCCCCCHHHCE
CIRGCPFGAYFSSNAATLVAAERTGRLQVRPNSIVTTLVYDERRQRASGVRILDAETGQE
EEECCCCCCEECCCCEEEEEECCCCEEEECCCCEEEEEEEHHHHHHHCCCEEEECCCCCC
EEFYAGVVFLCASAVASAWILLNSASARFPNGFGNGSDQVGRNLMDHHLGVGASALVDGF
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
EDRYYSGRRPNGLYIPRFRNLGDAASRRPDYLRGFGYQGGAGRLGWDRPTEGFGAERKQA
HHHHCCCCCCCCEECCCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
LSQPGPWGVRLGGFGEILPYADNRMTLNREVKDRYGLPTLSFDAAIGDNEAAMRKDMAAA
HCCCCCCEEEECCCCCCCCCCCCCEEECCHHHHHCCCCCEEECCCCCCCHHHHHHHHHHH
AAEMLEAAGFKNVAPYEGDYALGLGIHEMGTARMGRDPTTSVLNARNQLHECPNVFVTDG
HHHHHHHCCCCCCCCCCCCEEEECCHHHHCCHHCCCCCHHHHHHHHHHHHHCCCEEEECC
AAMTSSACVNPSLTYMALTARAAAYAAEAGRKGDL
CHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]