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The map label for this gene is 197105587

Identifier: 197105587

GI number: 197105587

Start: 2390949

End: 2392376

Strand: Direct

Name: 197105587

Synonym: PHZ_c2124

Alternate gene names: NA

Gene position: 2390949-2392376 (Clockwise)

Preceding gene: 197105586

Following gene: 197105588

Centisome position: 59.83

GC content: 70.52

Gene sequence:

>1428_bases
GTGGCGGTGATCGGCGCGGGCATGGCCGGCATCCTGGCGGGCGCCAAGCTTCGCGAGCGCGGCGTCGACTGCGTGATCTT
CGAGAAGGCGGACCGCGTCGGCGGGACCTGGCGCGAGAACACCTATCCGGGCCTGGCCTGCGACGTGCCGGCCCACTGGT
ACACCTATTCCTTCGCCCGCAATCCGGAGTGGGACACGCTGCTGGCCGCGGGGCCGGACATCCAGGCCTATTTCGAGCGT
GTGGCGCGCGACTACGGCGTGCTTCCGCTCGTCCGCTTCGGCGACGAGGTGGTGAGCCTCCGGTACGTCGACGGCGGCTG
GGAGGTCGCCACCGCGTCGGGCCATCGCGACCGGTTCGACGTGGTGATCAGCGCCGCGGGAGTGCTGCACCATCCCAACA
TCCCCAAGTTCGAGGGGGCGGAGTCCTTCAAGGGGGCCATGTTCCACTCCGCGCGCTGGGATCACAGCACGCCGCTGGAC
GGGCGCCGCATCGGCGTGATCGGCACCGGTTCGACCGCCGCCCAGCTCACCGCCGCGCTCGTGCCGCGCGCCGAGCGTTT
CGACCTCTTCCAGCGCACCGCCCAATGGGTGCTGCCGCGCCCGAACCTGGCCTACACCGACGAGGAGAAGGCAAGGTACC
GGGCCGACCCCGCGGCCCTCGAGGCCCTCGTCCAGCAGTACCGCTCCAAGACGATCGACGGCTATGCGACCGCCGTCCTC
GACTACGACTCCCCGCAGCTCGCCGAGATCGAGCGCCTGTGCCGGGAGAACCTGGAGACGGTGCGCGATCCCGACCTGCG
CCGCCGGCTGACGCCGGACTACCGGGCCGCGTGCAAGCGGTTGGTGATCTCGAGCGAGTTCTACGGCGCGATCCAGCAGC
CCAACGCCAACCTCGTCACCGCGCCCATCGCGCGGATCGAGCCGGAAGGCGTGCGGACGGCCGACGGGATCCTGCACGAA
CTGGACGTCCTGGTGCTCGCCACCGGCTTCCACACGGACCGCTTCATCCGCCCGGCCAAGGTGATCGGCCGTGGCGGCGC
CGACCTGGACGCGGTGTGGGGCGACCACCCGGTCGCCTACCTCTCGGTGACGGTGCCGGACTTCCCGAACTTCTTCATGC
TGGGCGGGCCGAACAGCCCGGTGGGGAACTTCTCGCTCATCGAGACCTGCGAGTGGCAGCTCGGCTACATCCTGCAGCTG
CTCGAGGGCATGCGCCGCGGCGACTACCGCGAGGCGAGCGCCACCCACGAGGCGATGGACCGCTTCGAGGACGAGCGCCG
GCGGGCGGCCGAGCGGACCGTGTGGGTGACCGGCTGCAAGAGCTGGTACCTCGACCGGCACGGCGTGCCGGCGTCCTGGA
CCTTCACCTACGCCCGCTTCGTGGAAGAGATGACCGCGCCGCGGATGGAGGACTTCGAGACACGATGA

Upstream 100 bases:

>100_bases
GGCAACCGTCACGGAACAGTGCGGAGGGAGGGCGCCGGTGAGCCACGCCTTGGAGAATGCAGACGCCGCAGCCGCCGGTC
AGGGCCTGCGCCCGATCCGC

Downstream 100 bases:

>100_bases
GGCCGGCCGGTGCGGCCCGCCCTCGTGGCGGCGCTCCGGCGCGATGGACAACCAGGGAGGAGAGGATGGTCACTCGGGAG
ATGATCGCCAGCGCTCTGCG

Product: flavin-containing monooxygenase FMO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MAVIGAGMAGILAGAKLRERGVDCVIFEKADRVGGTWRENTYPGLACDVPAHWYTYSFARNPEWDTLLAAGPDIQAYFER
VARDYGVLPLVRFGDEVVSLRYVDGGWEVATASGHRDRFDVVISAAGVLHHPNIPKFEGAESFKGAMFHSARWDHSTPLD
GRRIGVIGTGSTAAQLTAALVPRAERFDLFQRTAQWVLPRPNLAYTDEEKARYRADPAALEALVQQYRSKTIDGYATAVL
DYDSPQLAEIERLCRENLETVRDPDLRRRLTPDYRAACKRLVISSEFYGAIQQPNANLVTAPIARIEPEGVRTADGILHE
LDVLVLATGFHTDRFIRPAKVIGRGGADLDAVWGDHPVAYLSVTVPDFPNFFMLGGPNSPVGNFSLIETCEWQLGYILQL
LEGMRRGDYREASATHEAMDRFEDERRRAAERTVWVTGCKSWYLDRHGVPASWTFTYARFVEEMTAPRMEDFETR

Sequences:

>Translated_475_residues
MAVIGAGMAGILAGAKLRERGVDCVIFEKADRVGGTWRENTYPGLACDVPAHWYTYSFARNPEWDTLLAAGPDIQAYFER
VARDYGVLPLVRFGDEVVSLRYVDGGWEVATASGHRDRFDVVISAAGVLHHPNIPKFEGAESFKGAMFHSARWDHSTPLD
GRRIGVIGTGSTAAQLTAALVPRAERFDLFQRTAQWVLPRPNLAYTDEEKARYRADPAALEALVQQYRSKTIDGYATAVL
DYDSPQLAEIERLCRENLETVRDPDLRRRLTPDYRAACKRLVISSEFYGAIQQPNANLVTAPIARIEPEGVRTADGILHE
LDVLVLATGFHTDRFIRPAKVIGRGGADLDAVWGDHPVAYLSVTVPDFPNFFMLGGPNSPVGNFSLIETCEWQLGYILQL
LEGMRRGDYREASATHEAMDRFEDERRRAAERTVWVTGCKSWYLDRHGVPASWTFTYARFVEEMTAPRMEDFETR
>Mature_474_residues
AVIGAGMAGILAGAKLRERGVDCVIFEKADRVGGTWRENTYPGLACDVPAHWYTYSFARNPEWDTLLAAGPDIQAYFERV
ARDYGVLPLVRFGDEVVSLRYVDGGWEVATASGHRDRFDVVISAAGVLHHPNIPKFEGAESFKGAMFHSARWDHSTPLDG
RRIGVIGTGSTAAQLTAALVPRAERFDLFQRTAQWVLPRPNLAYTDEEKARYRADPAALEALVQQYRSKTIDGYATAVLD
YDSPQLAEIERLCRENLETVRDPDLRRRLTPDYRAACKRLVISSEFYGAIQQPNANLVTAPIARIEPEGVRTADGILHEL
DVLVLATGFHTDRFIRPAKVIGRGGADLDAVWGDHPVAYLSVTVPDFPNFFMLGGPNSPVGNFSLIETCEWQLGYILQLL
EGMRRGDYREASATHEAMDRFEDERRRAAERTVWVTGCKSWYLDRHGVPASWTFTYARFVEEMTAPRMEDFETR

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=221, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4503755, Length=219, Percent_Identity=26.4840182648402, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI50541965, Length=219, Percent_Identity=26.4840182648402, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI50541961, Length=219, Percent_Identity=26.4840182648402, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI221316674, Length=221, Percent_Identity=28.5067873303167, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI221316678, Length=221, Percent_Identity=28.5067873303167, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4503759, Length=222, Percent_Identity=27.027027027027, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI221316672, Length=221, Percent_Identity=28.5067873303167, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25145785, Length=213, Percent_Identity=23.4741784037559, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19922866, Length=320, Percent_Identity=22.8125, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 53239; Mature: 53107

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVIGAGMAGILAGAKLRERGVDCVIFEKADRVGGTWRENTYPGLACDVPAHWYTYSFAR
CCEECCCHHHHHHCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCEEEEECC
NPEWDTLLAAGPDIQAYFERVARDYGVLPLVRFGDEVVSLRYVDGGWEVATASGHRDRFD
CCCCCEEEECCCCHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCEEEEECCCCCCCEE
VVISAAGVLHHPNIPKFEGAESFKGAMFHSARWDHSTPLDGRRIGVIGTGSTAAQLTAAL
EEEEECCCEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
VPRAERFDLFQRTAQWVLPRPNLAYTDEEKARYRADPAALEALVQQYRSKTIDGYATAVL
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEE
DYDSPQLAEIERLCRENLETVRDPDLRRRLTPDYRAACKRLVISSEFYGAIQQPNANLVT
ECCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEE
APIARIEPEGVRTADGILHELDVLVLATGFHTDRFIRPAKVIGRGGADLDAVWGDHPVAY
CCHHHCCCCCCCHHHHHHHHHCEEEEEECCCCCHHCCHHHHHCCCCCCCCHHCCCCCEEE
LSVTVPDFPNFFMLGGPNSPVGNFSLIETCEWQLGYILQLLEGMRRGDYREASATHEAMD
EEEECCCCCCEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RFEDERRRAAERTVWVTGCKSWYLDRHGVPASWTFTYARFVEEMTAPRMEDFETR
HHHHHHHHHHHCEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure 
AVIGAGMAGILAGAKLRERGVDCVIFEKADRVGGTWRENTYPGLACDVPAHWYTYSFAR
CEECCCHHHHHHCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCEEEEECC
NPEWDTLLAAGPDIQAYFERVARDYGVLPLVRFGDEVVSLRYVDGGWEVATASGHRDRFD
CCCCCEEEECCCCHHHHHHHHHHHCCCCHHHHCCCEEEEEEEECCCEEEEECCCCCCCEE
VVISAAGVLHHPNIPKFEGAESFKGAMFHSARWDHSTPLDGRRIGVIGTGSTAAQLTAAL
EEEEECCCEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
VPRAERFDLFQRTAQWVLPRPNLAYTDEEKARYRADPAALEALVQQYRSKTIDGYATAVL
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEE
DYDSPQLAEIERLCRENLETVRDPDLRRRLTPDYRAACKRLVISSEFYGAIQQPNANLVT
ECCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEE
APIARIEPEGVRTADGILHELDVLVLATGFHTDRFIRPAKVIGRGGADLDAVWGDHPVAY
CCHHHCCCCCCCHHHHHHHHHCEEEEEECCCCCHHCCHHHHHCCCCCCCCHHCCCCCEEE
LSVTVPDFPNFFMLGGPNSPVGNFSLIETCEWQLGYILQLLEGMRRGDYREASATHEAMD
EEEECCCCCCEEEECCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RFEDERRRAAERTVWVTGCKSWYLDRHGVPASWTFTYARFVEEMTAPRMEDFETR
HHHHHHHHHHHCEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]