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The map label for this gene is alsR [H]

Identifier: 197105583

GI number: 197105583

Start: 2385674

End: 2386570

Strand: Reverse

Name: alsR [H]

Synonym: PHZ_c2120

Alternate gene names: 197105583

Gene position: 2386570-2385674 (Counterclockwise)

Preceding gene: 197105592

Following gene: 197105582

Centisome position: 59.72

GC content: 75.47

Gene sequence:

>897_bases
GTGGAGCTGCGCCAGCTTCGGCAGTTCGTCACCCTCGCCGAGACCCTGAACTTCCACCGGGCGGCGGCGGCGCTGAACAT
GACCCAGCCGCCCCTGTCCCTGTCGATCCGCAAGCTGGAGGACGAGCTGGGCGCGGCGCTGTTCGAGCGGCACGCCCGCG
GCGTGACGCTGACCGAGGCCGGGCGCGCGGCCCTGGGGCCCGCCCGCGACGCCCTCGCCGCCGCCGACGCAGCCGCGCAG
GCGGCCCGCCAGACCGCCCGGGGCGAGCGGGGGCGGGTCCGCGTCGGCTTCGTCGGATCGGCCACCTACGGCCTGGTGCC
CGCCATCGTGCCGCGCTTCCACGCCCAGCATCCGGGCATCGAGCTCAGTCTCAAGGAGGCGACCAGCCTGGAGGGCCTGC
GCGGCCTGGAGGCGGGCGAGCTCGACGTCGCCCTCGTGCGCACGCCGCTGCTGCAGGAGGCCTCGGTGGCCCTGGAGCCG
CTCTCCCAGGAGCCGCTGATGCTGATCGCGCCGCCGGCATGGGGACCGCCCGCCGCCGGCCGCGTCCGGCTGGAGGACCT
GAAGGACGAGGCCTTCGTCATGTACGACCGGGTGCACGCGCCGAACATCCGCGCCCAGACGCTGATGGCCTGCGAGGCGG
CGGGCTTCCTGCCGCGGGTGGCGGAGGAGGCGGCCAACATCCACACCCTCATCGCCCTGGTGGAGAGCGGCCTGGGCCTG
GCCTTCGTCCCGTCGGTGATGCGGCGGGCGGCCGAGGGGCGGGTCCATTGCCTGGAGCTCACCGCCGCGGGACGTCCGCT
GCAGATCGGCTTCGGCCTGGCGACCCGGCAGGGGGAGCGCCGCCTCACCGTGCAGGCGTTCGCGGCCACGGCGCGGGAAG
CCGCCCAAACGATCTAG

Upstream 100 bases:

>100_bases
CAGCATGCGGGCCCGGGCCTCCTTTTGCGGCGCGACCCTATTGGCCCCGTGGGCCTCCGGCCAATATCATTGCGTCGATG
ATCGATAGCGGAGGCATATC

Downstream 100 bases:

>100_bases
GCGGCATATTGGTTTGCCCGAATTCGATATTGGCTCCGGGCGCCATCCGGCCGTAGCGTCGCCGTCGATGCTGGAGACCC
TGGATCTTGCGACCATTCCG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MELRQLRQFVTLAETLNFHRAAAALNMTQPPLSLSIRKLEDELGAALFERHARGVTLTEAGRAALGPARDALAAADAAAQ
AARQTARGERGRVRVGFVGSATYGLVPAIVPRFHAQHPGIELSLKEATSLEGLRGLEAGELDVALVRTPLLQEASVALEP
LSQEPLMLIAPPAWGPPAAGRVRLEDLKDEAFVMYDRVHAPNIRAQTLMACEAAGFLPRVAEEAANIHTLIALVESGLGL
AFVPSVMRRAAEGRVHCLELTAAGRPLQIGFGLATRQGERRLTVQAFAATAREAAQTI

Sequences:

>Translated_298_residues
MELRQLRQFVTLAETLNFHRAAAALNMTQPPLSLSIRKLEDELGAALFERHARGVTLTEAGRAALGPARDALAAADAAAQ
AARQTARGERGRVRVGFVGSATYGLVPAIVPRFHAQHPGIELSLKEATSLEGLRGLEAGELDVALVRTPLLQEASVALEP
LSQEPLMLIAPPAWGPPAAGRVRLEDLKDEAFVMYDRVHAPNIRAQTLMACEAAGFLPRVAEEAANIHTLIALVESGLGL
AFVPSVMRRAAEGRVHCLELTAAGRPLQIGFGLATRQGERRLTVQAFAATAREAAQTI
>Mature_298_residues
MELRQLRQFVTLAETLNFHRAAAALNMTQPPLSLSIRKLEDELGAALFERHARGVTLTEAGRAALGPARDALAAADAAAQ
AARQTARGERGRVRVGFVGSATYGLVPAIVPRFHAQHPGIELSLKEATSLEGLRGLEAGELDVALVRTPLLQEASVALEP
LSQEPLMLIAPPAWGPPAAGRVRLEDLKDEAFVMYDRVHAPNIRAQTLMACEAAGFLPRVAEEAANIHTLIALVESGLGL
AFVPSVMRRAAEGRVHCLELTAAGRPLQIGFGLATRQGERRLTVQAFAATAREAAQTI

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=242, Percent_Identity=33.8842975206612, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=35.6, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790399, Length=249, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790208, Length=276, Percent_Identity=29.3478260869565, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787601, Length=197, Percent_Identity=32.994923857868, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI157672245, Length=231, Percent_Identity=32.9004329004329, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI145693105, Length=167, Percent_Identity=31.7365269461078, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87081904, Length=147, Percent_Identity=34.0136054421769, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787806, Length=290, Percent_Identity=27.2413793103448, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=24.8, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=251, Percent_Identity=23.9043824701195, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790262, Length=300, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788297, Length=262, Percent_Identity=27.4809160305344, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788481, Length=269, Percent_Identity=25.2788104089219, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786401, Length=185, Percent_Identity=29.7297297297297, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31799; Mature: 31799

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRQLRQFVTLAETLNFHRAAAALNMTQPPLSLSIRKLEDELGAALFERHARGVTLTEA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECC
GRAALGPARDALAAADAAAQAARQTARGERGRVRVGFVGSATYGLVPAIVPRFHAQHPGI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCE
ELSLKEATSLEGLRGLEAGELDVALVRTPLLQEASVALEPLSQEPLMLIAPPAWGPPAAG
EEEEHHHHCHHHHCCCCCCCCEEEEHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
RVRLEDLKDEAFVMYDRVHAPNIRAQTLMACEAAGFLPRVAEEAANIHTLIALVESGLGL
EEEHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCH
AFVPSVMRRAAEGRVHCLELTAAGRPLQIGFGLATRQGERRLTVQAFAATAREAAQTI
HHHHHHHHHHHCCCEEEEEEECCCCCEEEECCEECCCCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELRQLRQFVTLAETLNFHRAAAALNMTQPPLSLSIRKLEDELGAALFERHARGVTLTEA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECC
GRAALGPARDALAAADAAAQAARQTARGERGRVRVGFVGSATYGLVPAIVPRFHAQHPGI
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCE
ELSLKEATSLEGLRGLEAGELDVALVRTPLLQEASVALEPLSQEPLMLIAPPAWGPPAAG
EEEEHHHHCHHHHCCCCCCCCEEEEHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
RVRLEDLKDEAFVMYDRVHAPNIRAQTLMACEAAGFLPRVAEEAANIHTLIALVESGLGL
EEEHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCH
AFVPSVMRRAAEGRVHCLELTAAGRPLQIGFGLATRQGERRLTVQAFAATAREAAQTI
HHHHHHHHHHHCCCEEEEEEECCCCCEEEECCEECCCCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]