Click here to switch to the map view.

The map label for this gene is mmgC [H]

Identifier: 197105582

GI number: 197105582

Start: 2384455

End: 2385606

Strand: Reverse

Name: mmgC [H]

Synonym: PHZ_c2119

Alternate gene names: 197105582

Gene position: 2385606-2384455 (Counterclockwise)

Preceding gene: 197105583

Following gene: 197105581

Centisome position: 59.7

GC content: 72.74

Gene sequence:

>1152_bases
ATGCTGGAGACCCTGGATCTTGCGACCATTCCGCCCGAGGACGAGGCGCTGCGCGGCCCCGTCCGCGCCTTCCTGGCCGA
GCGGCTGGCCGGCGTTCCCGCCGCGACCCGCGCCCGCACCTGGATGGGCTTCGACGCCGAATTCACCCGCGCCCTCGCGG
CCAAGGGCTGGGTCGGCCTGACGCTGCCGCAGGCGTACGGCGGGGGCGGGCGCAGCCACTTCGCCCGCTTCGTGCTGATC
GAGGAGCTGCTGGCGGCCGGGGCGCCGGTGGCCGCCCACTGGATCGCCGAGCGCCAGAGCGCGCCGCTGATCCTGCGCTA
CGGGACCGAGGCCCAGAAGCAGCGCATCGTGCCGGCGGTGTGCCGCGGCGAGGCCTTCTTCTGCATCGGCATGAGCGAGC
CGAACTCGGGCTCGGACCTGGCCAGCGTGCGGAGCCGCGCCGAGAAGGTGGACGGCGGCTGGAAGCTGTCGGGCACGAAG
ATCTGGACGACCTACGGCCACAAGGCCGACTTCATGATCGCCCTGGTGCGCACCAGCGGGACGCCCGAGGACCGCTCGGC
CGGGCTGTCCCAGATGCTGATCGACATGCGCGCCCCGGGCGTGACGGCGCGGCCGATCCGCGACCTCGCGGGCGACGAGC
ACTTCTCGGAGGTGCACTTCGACGAGGTTGTCCTGCCCGAGGACGCGCTGCTGGGCCGCGAGGGCGCCGGCTGGGAGCAG
GTGAACGCCGAGCTGGCCTTCGAGCGTTCGGGCCCCGAGCGGATCTATTCCTCCACCGTGCTGGTGGACGCCTGGCTGGA
CCATGTGCGGGGCAGGGGGAACGTCACCGACGCCGAGCGCGTGCTGGCCGGCCGGCTGCTGGCCGAGCTTTCGGCCCTGC
GGAACATGTCGCTCTCGGTCACCGCCATGCTCGCGGCGGGCAAGAGCCCGGTGGTCGAGGCCTCGGTCGTGAAGGACCTG
GGGACCGCCTTCGAACAGCAGATCCCCGCCCTGATCGCCGACCATCTGGCGGGCGAGCCCGAGGGCTCGGTCCCGGGTCA
CCTGCTGGCGGCATTGGAATACGTGGCCGGCATGTGCCCGACGTTCTCCCTGCGCGGCGGCACGCGCGAGATCCTGCGCG
GGATCATCGCCCGCGGCCTCGGCCTGAGGTGA

Upstream 100 bases:

>100_bases
GCCACGGCGCGGGAAGCCGCCCAAACGATCTAGGCGGCATATTGGTTTGCCCGAATTCGATATTGGCTCCGGGCGCCATC
CGGCCGTAGCGTCGCCGTCG

Downstream 100 bases:

>100_bases
CCCGAATGAGCGACCTGATCGCCGAACAGTACGCGCGCCTGCTGGACAGCCTGCCGGCGGACGATCCCTGGCCCGCGCTC
GAGGAGTCCGGCTTCCTGGA

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MLETLDLATIPPEDEALRGPVRAFLAERLAGVPAATRARTWMGFDAEFTRALAAKGWVGLTLPQAYGGGGRSHFARFVLI
EELLAAGAPVAAHWIAERQSAPLILRYGTEAQKQRIVPAVCRGEAFFCIGMSEPNSGSDLASVRSRAEKVDGGWKLSGTK
IWTTYGHKADFMIALVRTSGTPEDRSAGLSQMLIDMRAPGVTARPIRDLAGDEHFSEVHFDEVVLPEDALLGREGAGWEQ
VNAELAFERSGPERIYSSTVLVDAWLDHVRGRGNVTDAERVLAGRLLAELSALRNMSLSVTAMLAAGKSPVVEASVVKDL
GTAFEQQIPALIADHLAGEPEGSVPGHLLAALEYVAGMCPTFSLRGGTREILRGIIARGLGLR

Sequences:

>Translated_383_residues
MLETLDLATIPPEDEALRGPVRAFLAERLAGVPAATRARTWMGFDAEFTRALAAKGWVGLTLPQAYGGGGRSHFARFVLI
EELLAAGAPVAAHWIAERQSAPLILRYGTEAQKQRIVPAVCRGEAFFCIGMSEPNSGSDLASVRSRAEKVDGGWKLSGTK
IWTTYGHKADFMIALVRTSGTPEDRSAGLSQMLIDMRAPGVTARPIRDLAGDEHFSEVHFDEVVLPEDALLGREGAGWEQ
VNAELAFERSGPERIYSSTVLVDAWLDHVRGRGNVTDAERVLAGRLLAELSALRNMSLSVTAMLAAGKSPVVEASVVKDL
GTAFEQQIPALIADHLAGEPEGSVPGHLLAALEYVAGMCPTFSLRGGTREILRGIIARGLGLR
>Mature_383_residues
MLETLDLATIPPEDEALRGPVRAFLAERLAGVPAATRARTWMGFDAEFTRALAAKGWVGLTLPQAYGGGGRSHFARFVLI
EELLAAGAPVAAHWIAERQSAPLILRYGTEAQKQRIVPAVCRGEAFFCIGMSEPNSGSDLASVRSRAEKVDGGWKLSGTK
IWTTYGHKADFMIALVRTSGTPEDRSAGLSQMLIDMRAPGVTARPIRDLAGDEHFSEVHFDEVVLPEDALLGREGAGWEQ
VNAELAFERSGPERIYSSTVLVDAWLDHVRGRGNVTDAERVLAGRLLAELSALRNMSLSVTAMLAAGKSPVVEASVVKDL
GTAFEQQIPALIADHLAGEPEGSVPGHLLAALEYVAGMCPTFSLRGGTREILRGIIARGLGLR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=269, Percent_Identity=30.1115241635688, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI226958414, Length=261, Percent_Identity=29.1187739463602, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI4501857, Length=388, Percent_Identity=23.1958762886598, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4501859, Length=326, Percent_Identity=25.1533742331288, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI4557233, Length=246, Percent_Identity=26.4227642276423, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI76496475, Length=362, Percent_Identity=26.7955801104972, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4557235, Length=362, Percent_Identity=26.7955801104972, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI21361497, Length=229, Percent_Identity=28.3842794759825, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI7656849, Length=197, Percent_Identity=26.3959390862944, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503943, Length=170, Percent_Identity=32.9411764705882, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI7669494, Length=170, Percent_Identity=32.9411764705882, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786223, Length=232, Percent_Identity=25.4310344827586, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081958, Length=207, Percent_Identity=26.0869565217391, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=308, Percent_Identity=29.5454545454545, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17506239, Length=196, Percent_Identity=31.6326530612245, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=236, Percent_Identity=28.8135593220339, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=247, Percent_Identity=31.1740890688259, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=187, Percent_Identity=32.0855614973262, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=240, Percent_Identity=30.8333333333333, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=188, Percent_Identity=28.1914893617021, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=245, Percent_Identity=24.8979591836735, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=212, Percent_Identity=26.4150943396226, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=211, Percent_Identity=24.6445497630332, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17505929, Length=203, Percent_Identity=26.1083743842365, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=207, Percent_Identity=28.0193236714976, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=212, Percent_Identity=23.5849056603774, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355753, Length=352, Percent_Identity=29.2613636363636, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281363737, Length=241, Percent_Identity=29.045643153527, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24666513, Length=336, Percent_Identity=22.9166666666667, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356377, Length=237, Percent_Identity=24.8945147679325, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41057; Mature: 41057

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETLDLATIPPEDEALRGPVRAFLAERLAGVPAATRARTWMGFDAEFTRALAAKGWVGL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCEEE
TLPQAYGGGGRSHFARFVLIEELLAAGAPVAAHWIAERQSAPLILRYGTEAQKQRIVPAV
ECCHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCHHHHHCCCHHH
CRGEAFFCIGMSEPNSGSDLASVRSRAEKVDGGWKLSGTKIWTTYGHKADFMIALVRTSG
HCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCEEEEEEECCC
TPEDRSAGLSQMLIDMRAPGVTARPIRDLAGDEHFSEVHFDEVVLPEDALLGREGAGWEQ
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHCCCCEECCCHHHCCCCCCCHHH
VNAELAFERSGPERIYSSTVLVDAWLDHVRGRGNVTDAERVLAGRLLAELSALRNMSLSV
HCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
TAMLAAGKSPVVEASVVKDLGTAFEQQIPALIADHLAGEPEGSVPGHLLAALEYVAGMCP
EEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
TFSLRGGTREILRGIIARGLGLR
CEECCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLETLDLATIPPEDEALRGPVRAFLAERLAGVPAATRARTWMGFDAEFTRALAAKGWVGL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCEEE
TLPQAYGGGGRSHFARFVLIEELLAAGAPVAAHWIAERQSAPLILRYGTEAQKQRIVPAV
ECCHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCHHHHHCCCHHH
CRGEAFFCIGMSEPNSGSDLASVRSRAEKVDGGWKLSGTKIWTTYGHKADFMIALVRTSG
HCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCEEEEEEECCC
TPEDRSAGLSQMLIDMRAPGVTARPIRDLAGDEHFSEVHFDEVVLPEDALLGREGAGWEQ
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHCCCCEECCCHHHCCCCCCCHHH
VNAELAFERSGPERIYSSTVLVDAWLDHVRGRGNVTDAERVLAGRLLAELSALRNMSLSV
HCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
TAMLAAGKSPVVEASVVKDLGTAFEQQIPALIADHLAGEPEGSVPGHLLAALEYVAGMCP
EEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
TFSLRGGTREILRGIIARGLGLR
CEECCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]