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The map label for this gene is yybO [H]

Identifier: 197105558

GI number: 197105558

Start: 2348380

End: 2349654

Strand: Reverse

Name: yybO [H]

Synonym: PHZ_c2095

Alternate gene names: 197105558

Gene position: 2349654-2348380 (Counterclockwise)

Preceding gene: 197105559

Following gene: 197105552

Centisome position: 58.8

GC content: 70.82

Gene sequence:

>1275_bases
ATGGCCCAGGACGCCCGCGCCGCCAGCGGCGGCTACCGGATCGTCGTGCTCGCGATCCTGATCCTCGCCTACACCTTCAA
CTTCCTCGACCGGCAGATCCTCGGGATCCTCGCCGGGCCCATCAAGCAGGAGCTGGGGCTCACCGACAGCCAGCTCGGGC
TGATGGGGGGCCTGGCCTTCGCGCTGTTCTACACTGGGCTCGGCATTCCGATCGCCTGGCTGGCCGACCGCTGGAGCCGG
ACCTGGATCATGACCGGGGCGCTGGCGCTGTGGAGCGGATTCACCGCCCTGTGCGGCCTAGCCGGCGGCTTCTGGCAGCT
GTTCCTGTGCCGCATGGGCGTTGGCGTGGGCGAGGCGGGCGGCGTCGCCCCGGCCTATTCGCTGATCGCCGACTACTTCC
CGAAGGAGCAGCGGGCGAGGGCGCTCGCGGCCTATTCGTTCGGCATCCCGATCGGCTCGGCCCTCGGCATCCTGTTCGGC
GGCCTGATCGCCCACGCCATCGACTGGCGGGCGGCCTTCATCGTGGTCGGCCTCGCCGGGGTCGCCCTGGCGCCGATCTT
CCGCCTCGTGGTCAAGGAGCCGCCGCGGGGCGCCATGGAAGGGCCGGCGGCCCCCATCCCCGCCGGCGCCGCCCCACCGC
GCGGCGGCATCGGCCGGCTGCTCGCCAAGCCCGCGTTCTGGCTCATCTCGCTGGGCGCGGCCGCCTCGTCGGTCTGCGGC
TACGGCGTGGCCTTCTGGCTGCCGTCGTTCTTCGAGCGCAGCCTGGGCATGAACCTCGTGGACCGCTCGCTCTTCCTGGG
CTCGATGACCCTCGTCGGCGGCGTCGCCGGGGTCTGGCTCGGAGGCTGGCTGGGCGACCGCCTGGGCCGGGCCCGCCCGG
CCTTCTACCTGCTGGTGCCGGCGGCGGCCTTCCTCGTGGCGCTGCCCTGCTTCTTCCTGGCCATCCAGGCCCAGAACCTG
TGGCTGGCCTTCGTCCTGTTCCTCATCCCCACCGGGCTCAACCTGGTCTGGCTGGGGCCGGTGATTACTGCGGTGCAGCA
TCTTGTCGCGCCCGCCGAACGCTCGACGGCCTCGGCCTGCTTCCTGTTCGTCAACAACCTGATCGGTCTGGGGCTGGGGA
CCTGGTTCTTCGGCGCTGTCTCGGATGCGCTCGCGCCGCATTTCGGTGCGGAATCGCTACGTTACGCGATCTATTCCGGT
CTCGGCTTCTATCTGGTCAGCGCCGGGCTGTTCGTCCTGGCGGCGCGGCGGCTGCACCACGACTGGGTCGAGTAA

Upstream 100 bases:

>100_bases
GGCCCGCCGCGGACCGTGACGCTCTCGCTCGAAGCGAAGTTCTAGTATCGGCCAACGCCCGGCTCACCCGAGCCGGGCGT
TTTCCTTCGCCGGAGTCTCC

Downstream 100 bases:

>100_bases
CGCATCATTTCACGTGGGGCTGAATTTGTGACTTGCGTGCAGTGCAGCAAAGAGGCATGAAGGTCTCGCCCTTTTGGGCG
TTTCCTCCCTAATGACTTGG

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MAQDARAASGGYRIVVLAILILAYTFNFLDRQILGILAGPIKQELGLTDSQLGLMGGLAFALFYTGLGIPIAWLADRWSR
TWIMTGALALWSGFTALCGLAGGFWQLFLCRMGVGVGEAGGVAPAYSLIADYFPKEQRARALAAYSFGIPIGSALGILFG
GLIAHAIDWRAAFIVVGLAGVALAPIFRLVVKEPPRGAMEGPAAPIPAGAAPPRGGIGRLLAKPAFWLISLGAAASSVCG
YGVAFWLPSFFERSLGMNLVDRSLFLGSMTLVGGVAGVWLGGWLGDRLGRARPAFYLLVPAAAFLVALPCFFLAIQAQNL
WLAFVLFLIPTGLNLVWLGPVITAVQHLVAPAERSTASACFLFVNNLIGLGLGTWFFGAVSDALAPHFGAESLRYAIYSG
LGFYLVSAGLFVLAARRLHHDWVE

Sequences:

>Translated_424_residues
MAQDARAASGGYRIVVLAILILAYTFNFLDRQILGILAGPIKQELGLTDSQLGLMGGLAFALFYTGLGIPIAWLADRWSR
TWIMTGALALWSGFTALCGLAGGFWQLFLCRMGVGVGEAGGVAPAYSLIADYFPKEQRARALAAYSFGIPIGSALGILFG
GLIAHAIDWRAAFIVVGLAGVALAPIFRLVVKEPPRGAMEGPAAPIPAGAAPPRGGIGRLLAKPAFWLISLGAAASSVCG
YGVAFWLPSFFERSLGMNLVDRSLFLGSMTLVGGVAGVWLGGWLGDRLGRARPAFYLLVPAAAFLVALPCFFLAIQAQNL
WLAFVLFLIPTGLNLVWLGPVITAVQHLVAPAERSTASACFLFVNNLIGLGLGTWFFGAVSDALAPHFGAESLRYAIYSG
LGFYLVSAGLFVLAARRLHHDWVE
>Mature_423_residues
AQDARAASGGYRIVVLAILILAYTFNFLDRQILGILAGPIKQELGLTDSQLGLMGGLAFALFYTGLGIPIAWLADRWSRT
WIMTGALALWSGFTALCGLAGGFWQLFLCRMGVGVGEAGGVAPAYSLIADYFPKEQRARALAAYSFGIPIGSALGILFGG
LIAHAIDWRAAFIVVGLAGVALAPIFRLVVKEPPRGAMEGPAAPIPAGAAPPRGGIGRLLAKPAFWLISLGAAASSVCGY
GVAFWLPSFFERSLGMNLVDRSLFLGSMTLVGGVAGVWLGGWLGDRLGRARPAFYLLVPAAAFLVALPCFFLAIQAQNLW
LAFVLFLIPTGLNLVWLGPVITAVQHLVAPAERSTASACFLFVNNLIGLGLGTWFFGAVSDALAPHFGAESLRYAIYSGL
GFYLVSAGLFVLAARRLHHDWVE

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=404, Percent_Identity=32.4257425742574, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI14042968, Length=404, Percent_Identity=32.4257425742574, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI215490100, Length=384, Percent_Identity=32.8125, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI215490102, Length=392, Percent_Identity=30.8673469387755, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI215490098, Length=352, Percent_Identity=31.5340909090909, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI185136021, Length=443, Percent_Identity=27.0880361173815, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI194239645, Length=438, Percent_Identity=27.8538812785388, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI2367379, Length=283, Percent_Identity=25.4416961130742, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082320, Length=301, Percent_Identity=24.9169435215947, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789152, Length=309, Percent_Identity=25.2427184466019, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789515, Length=311, Percent_Identity=25.08038585209, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082404, Length=304, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17557872, Length=418, Percent_Identity=27.2727272727273, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17539092, Length=439, Percent_Identity=26.1958997722096, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71992409, Length=451, Percent_Identity=28.6031042128603, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI193209775, Length=460, Percent_Identity=25, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24654037, Length=384, Percent_Identity=29.4270833333333, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24654041, Length=384, Percent_Identity=29.4270833333333, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24654039, Length=385, Percent_Identity=29.0909090909091, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17864456, Length=385, Percent_Identity=29.0909090909091, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24654044, Length=256, Percent_Identity=29.6875, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24640209, Length=375, Percent_Identity=25.6, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44834; Mature: 44703

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCC
>Mature Secondary Structure 
AQDARAASGGYRIVVLAILILAYTFNFLDRQILGILAGPIKQELGLTDSQLGLMGGLAF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH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HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]