BacMap

Definition	Phenylobacterium zucineum HLK1, complete genome.
Accession	NC_011144
Length	3,996,255

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 197105536

GI number: 197105536

Start: 2318369

End: 2319121

Strand: Reverse

Name: fabG [H]

Synonym: PHZ_c2073

Alternate gene names: 197105536

Gene position: 2319121-2318369 (Counterclockwise)

Preceding gene: 197105537

Following gene: 197105535

Centisome position: 58.03

GC content: 71.45

Gene sequence:

>753_bases
ATGGCGGGGGCGATCTATCCCGGCATGAAGGACCGCGTGGTCTTCGTCACCGGCGGCGCCTCGGGCATCGGGGCCGCCTT
CGTCGAGCAGTTCCACGCCCAGGGCTCCAAGGTCGCCTTCGTCGACCTGCAGGCCGATGCGGGCGAGGCCCTGGCCGGGC
GGCTGGGGCAGGGCGCCTGGTTCCGCCGCTGCGACGTGACCGACGTGCCGGCGCTGCAGGCGGCGATCCGCGACGCGGCC
CAGGCGCTTGGGCCCGTCACGGTCCTGATCAACAACGTCGCCAACGACACGCGGCATGAGGCCGCCGAGACCTCGATGGA
CGCCTGGCGCAAGGGCCTGGCGGTGAACCTCGATCCGGCGTTCGCGGCCTCGGTGGCGGTCTATCCGATGATGAAGGCGG
CGGGCGGTGGCTCGATCGTGAACGTCAGCTCGATCAACGCCTTGTGGGGGCCGGCTCACATGGCGACCTATGTGGCGGCC
AAGGGCGCGATCAACTCCCTCAGCAAGGGGCTGGCCCGCGAATGGGGCCCCGACCGCATCCGGGTGAACGCCCTGTCGCC
GGGCTGGGTGGTGACCGAGCGCCAGCTGGAGCTGTGGCTGACGCCGCAGGCCGAGGCCGCCTGGCGCGAGCAGGTGGCCC
TGAAGGACCGCATCCTTCCCGAGGACATCGCCCGGGCGGCGCTGTTCCTGGCCAGCGACGAGAGCCGGATGATGACCGGC
CAGAACCTGATCGTCGATGCGGGGCGGCTCTGA

Upstream 100 bases:

>100_bases
ACAAGCTCTACATCGACACCGTGCTGCAGGCGGACCGCGGCGCCGACCTCGACTTCCTGGTCGGCAAGTCCAGCCCCGAC
GTCACCCGCGAGTCCCACTG

Downstream 100 bases:

>100_bases
TGGGCGCCGCGCTGCTGGCCTGCGACTGGGGCACGACCAACCTTCGCGCCTGGACGCTGGACGCGGGCGGCGGGATCGTC
GGCGACCGCGATTTCCCCGG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAGAIYPGMKDRVVFVTGGASGIGAAFVEQFHAQGSKVAFVDLQADAGEALAGRLGQGAWFRRCDVTDVPALQAAIRDAA
QALGPVTVLINNVANDTRHEAAETSMDAWRKGLAVNLDPAFAASVAVYPMMKAAGGGSIVNVSSINALWGPAHMATYVAA
KGAINSLSKGLAREWGPDRIRVNALSPGWVVTERQLELWLTPQAEAAWREQVALKDRILPEDIARAALFLASDESRMMTG
QNLIVDAGRL

Sequences:

>Translated_250_residues
MAGAIYPGMKDRVVFVTGGASGIGAAFVEQFHAQGSKVAFVDLQADAGEALAGRLGQGAWFRRCDVTDVPALQAAIRDAA
QALGPVTVLINNVANDTRHEAAETSMDAWRKGLAVNLDPAFAASVAVYPMMKAAGGGSIVNVSSINALWGPAHMATYVAA
KGAINSLSKGLAREWGPDRIRVNALSPGWVVTERQLELWLTPQAEAAWREQVALKDRILPEDIARAALFLASDESRMMTG
QNLIVDAGRL
>Mature_249_residues
AGAIYPGMKDRVVFVTGGASGIGAAFVEQFHAQGSKVAFVDLQADAGEALAGRLGQGAWFRRCDVTDVPALQAAIRDAAQ
ALGPVTVLINNVANDTRHEAAETSMDAWRKGLAVNLDPAFAASVAVYPMMKAAGGGSIVNVSSINALWGPAHMATYVAAK
GAINSLSKGLAREWGPDRIRVNALSPGWVVTERQLELWLTPQAEAAWREQVALKDRILPEDIARAALFLASDESRMMTGQ
NLIVDAGRL

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=31.3008130081301, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=29.5081967213115, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=33.8912133891213, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=30.672268907563, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=28.2352941176471, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=31.4159292035398, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=26.7206477732794, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI31542939, Length=217, Percent_Identity=30.4147465437788, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=28.6259541984733, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4758504, Length=196, Percent_Identity=33.1632653061224, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=27.4611398963731, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI109715829, Length=254, Percent_Identity=28.740157480315, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI224922801, Length=169, Percent_Identity=31.9526627218935, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI83715985, Length=181, Percent_Identity=32.5966850828729, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4503301, Length=213, Percent_Identity=24.8826291079812, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=28.5123966942149, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=29.3172690763052, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=31.6666666666667, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=29.535864978903, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=27.4590163934426, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=29.5081967213115, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=29.6153846153846, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=25.7142857142857, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789378, Length=239, Percent_Identity=28.0334728033473, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=30.2904564315353, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786812, Length=247, Percent_Identity=31.5789473684211, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=27.5303643724696, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=35.1020408163265, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=27.5720164609054, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=28.8, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=27.0588235294118, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=27.8225806451613, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=28.0769230769231, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=227, Percent_Identity=28.6343612334802, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=257, Percent_Identity=28.4046692607004, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=28.9156626506024, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=28.5171102661597, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=277, Percent_Identity=25.6317689530686, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=28.8973384030418, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=26.2357414448669, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=26.7175572519084, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=25.6809338521401, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=248, Percent_Identity=24.5967741935484, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=240, Percent_Identity=25.8333333333333, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=27.1604938271605, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=26.9076305220884, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=28.2258064516129, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=24.896265560166, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=27.5303643724696, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24644337, Length=247, Percent_Identity=29.1497975708502, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357673, Length=248, Percent_Identity=25.4032258064516, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=28.6885245901639, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=203, Percent_Identity=26.1083743842365, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=24.8704663212435, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26451; Mature: 26320

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGAIYPGMKDRVVFVTGGASGIGAAFVEQFHAQGSKVAFVDLQADAGEALAGRLGQGAW
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHCCCCCE
FRRCDVTDVPALQAAIRDAAQALGPVTVLINNVANDTRHEAAETSMDAWRKGLAVNLDPA
EEECCCCCCHHHHHHHHHHHHHHCCHHEEHHHHCCHHHHHHHHHHHHHHHCCCEEECCHH
FAASVAVYPMMKAAGGGSIVNVSSINALWGPAHMATYVAAKGAINSLSKGLAREWGPDRI
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RVNALSPGWVVTERQLELWLTPQAEAAWREQVALKDRILPEDIARAALFLASDESRMMTG
EEEEECCCEEEEECEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCEECC
QNLIVDAGRL
CEEEEECCCC
>Mature Secondary Structure 
AGAIYPGMKDRVVFVTGGASGIGAAFVEQFHAQGSKVAFVDLQADAGEALAGRLGQGAW
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHCCCCCE
FRRCDVTDVPALQAAIRDAAQALGPVTVLINNVANDTRHEAAETSMDAWRKGLAVNLDPA
EEECCCCCCHHHHHHHHHHHHHHCCHHEEHHHHCCHHHHHHHHHHHHHHHCCCEEECCHH
FAASVAVYPMMKAAGGGSIVNVSSINALWGPAHMATYVAAKGAINSLSKGLAREWGPDRI
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RVNALSPGWVVTERQLELWLTPQAEAAWREQVALKDRILPEDIARAALFLASDESRMMTG
EEEEECCCEEEEECEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCEECC
QNLIVDAGRL
CEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]