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The map label for this gene is galE [H]

Identifier: 197105532

GI number: 197105532

Start: 2313158

End: 2314204

Strand: Reverse

Name: galE [H]

Synonym: PHZ_c2069

Alternate gene names: 197105532

Gene position: 2314204-2313158 (Counterclockwise)

Preceding gene: 197105534

Following gene: 197105531

Centisome position: 57.91

GC content: 73.35

Gene sequence:

>1047_bases
ATGGATCGGGGATCGAAGCCCGCCGTCCTGGTGACGGGCGGAGCCGGCTACATCGGCGCACACACCGCGAAGGCTCTGAG
CGAGCGGGGATTCTTCCCCGTGGTGTTCGACAGCCTCAGTTCAGGCTTCCGCGAGGCCGTCCAGTGGGGCGCCTTCGTCC
ACGGAGACATCCGCGACACCCGCGCGCTGGCCGAGGCGATCTCGGACCACGGCGTCAAATCGGTGATCCACTTCGCCGGC
CTGATCGAGGTGGGCCGCTCGGTCGCCCAGCCCGACATCTTCTGGGAGATCAACGTCGGCGGCACCGTCAGCCTGCTGAC
CGCCATGCGCGAGCGCGGGGTCGAGCGGCTGGTGTTCTCGTCCAGCGCGGCGGTCTACGGCCAGGGCGGGCGAGGGCCGC
TCGAGACCATCCCCGAGAGCGCCGGCAAGGCGCCCGCCAGCCCCTATGGCGACACGAAGCTGGCCTGCGAGTGGATGATC
GAGGCCCAGTGCCGCGCCTATGGCCTGACGGCCGTGGCGCTGCGCTACTTCAACGCCGCGGGGGCCGACCCCTCCGGCCG
GATCGGCGAGGCCCACGAGCCTGAGACGCACCTCCTGCCGCTCGCCATCGCCGCGGGGCTGGGGGAGGGCAAGCCGCTGA
CCGTGTTCGGCGAGGACTTCGACACCCCGGACGGCACCTGCCTGCGCGACTACATCCACGTGAACGACCTGGCCGCCGCC
CACGTCGCCGCCCTGGAGGTCGACCTGCCCGCCGGCGCCTACGAGGCGGTGAACGTCGGCACGGGGCAGGGCCACTCTGT
GCGCGAGGTGGTCGAGGCCGTCGGCCGCGCCCTCGGCCGGCCCGTGCCGCACAGCATCGGCGCCCGCCGGGCCGGCGATC
CGCCGAGCCTGGTGGCCGACGCCTCGCGGGCGCGGGATCTGCTCGGCTGGGAGCCGGTCTGCTCGACCCTCGACCGCATC
GTCGCCGACGCCCTGCGGTGGGAGGCCCAGCCGGCTTACGGATCGGGCCGCCGCGCCGGCGGCCGCAAAGCTGAAACCGC
GAGCTGA

Upstream 100 bases:

>100_bases
CGTCACAACCCGACGGTTCAAAGCCGCCGCGGAAGCAATCGTTCCCCATCCTGCCGAATGGGGCTGGAACCGGCGCCCGG
GGGCGGGAATTATCGGCCGC

Downstream 100 bases:

>100_bases
ACAGTCGACTTTCCGACTTAAGCTAAAGTCGCGGTCTAGCTTTCTGCGGCTATCTTTTGATTACTGAATACTTTTGGCCA
GTCTCAAGAAGAGGGCGGGA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MDRGSKPAVLVTGGAGYIGAHTAKALSERGFFPVVFDSLSSGFREAVQWGAFVHGDIRDTRALAEAISDHGVKSVIHFAG
LIEVGRSVAQPDIFWEINVGGTVSLLTAMRERGVERLVFSSSAAVYGQGGRGPLETIPESAGKAPASPYGDTKLACEWMI
EAQCRAYGLTAVALRYFNAAGADPSGRIGEAHEPETHLLPLAIAAGLGEGKPLTVFGEDFDTPDGTCLRDYIHVNDLAAA
HVAALEVDLPAGAYEAVNVGTGQGHSVREVVEAVGRALGRPVPHSIGARRAGDPPSLVADASRARDLLGWEPVCSTLDRI
VADALRWEAQPAYGSGRRAGGRKAETAS

Sequences:

>Translated_348_residues
MDRGSKPAVLVTGGAGYIGAHTAKALSERGFFPVVFDSLSSGFREAVQWGAFVHGDIRDTRALAEAISDHGVKSVIHFAG
LIEVGRSVAQPDIFWEINVGGTVSLLTAMRERGVERLVFSSSAAVYGQGGRGPLETIPESAGKAPASPYGDTKLACEWMI
EAQCRAYGLTAVALRYFNAAGADPSGRIGEAHEPETHLLPLAIAAGLGEGKPLTVFGEDFDTPDGTCLRDYIHVNDLAAA
HVAALEVDLPAGAYEAVNVGTGQGHSVREVVEAVGRALGRPVPHSIGARRAGDPPSLVADASRARDLLGWEPVCSTLDRI
VADALRWEAQPAYGSGRRAGGRKAETAS
>Mature_348_residues
MDRGSKPAVLVTGGAGYIGAHTAKALSERGFFPVVFDSLSSGFREAVQWGAFVHGDIRDTRALAEAISDHGVKSVIHFAG
LIEVGRSVAQPDIFWEINVGGTVSLLTAMRERGVERLVFSSSAAVYGQGGRGPLETIPESAGKAPASPYGDTKLACEWMI
EAQCRAYGLTAVALRYFNAAGADPSGRIGEAHEPETHLLPLAIAAGLGEGKPLTVFGEDFDTPDGTCLRDYIHVNDLAAA
HVAALEVDLPAGAYEAVNVGTGQGHSVREVVEAVGRALGRPVPHSIGARRAGDPPSLVADASRARDLLGWEPVCSTLDRI
VADALRWEAQPAYGSGRRAGGRKAETAS

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=349, Percent_Identity=41.8338108882521, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI56118217, Length=349, Percent_Identity=41.8338108882521, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI189083684, Length=349, Percent_Identity=41.8338108882521, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI7657641, Length=280, Percent_Identity=27.1428571428571, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI116268111, Length=247, Percent_Identity=30.3643724696356, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI42516563, Length=322, Percent_Identity=23.6024844720497, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786974, Length=339, Percent_Identity=40.4129793510324, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1788353, Length=337, Percent_Identity=29.673590504451, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=29.0419161676647, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788365, Length=321, Percent_Identity=21.8068535825545, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=35.0574712643678, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=35.8381502890173, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17568069, Length=336, Percent_Identity=27.0833333333333, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=343, Percent_Identity=26.530612244898, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=348, Percent_Identity=38.7931034482759, Blast_Score=215, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6321437, Length=249, Percent_Identity=29.3172690763052, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19923002, Length=350, Percent_Identity=36.2857142857143, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI21356223, Length=324, Percent_Identity=23.1481481481481, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36431; Mature: 36431

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRGSKPAVLVTGGAGYIGAHTAKALSERGFFPVVFDSLSSGFREAVQWGAFVHGDIRDT
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEECCHHHH
RALAEAISDHGVKSVIHFAGLIEVGRSVAQPDIFWEINVGGTVSLLTAMRERGVERLVFS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHC
SSAAVYGQGGRGPLETIPESAGKAPASPYGDTKLACEWMIEAQCRAYGLTAVALRYFNAA
CCCEEEECCCCCHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GADPSGRIGEAHEPETHLLPLAIAAGLGEGKPLTVFGEDFDTPDGTCLRDYIHVNDLAAA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
HVAALEVDLPAGAYEAVNVGTGQGHSVREVVEAVGRALGRPVPHSIGARRAGDPPSLVAD
HHHEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHH
ASRARDLLGWEPVCSTLDRIVADALRWEAQPAYGSGRRAGGRKAETAS
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDRGSKPAVLVTGGAGYIGAHTAKALSERGFFPVVFDSLSSGFREAVQWGAFVHGDIRDT
CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEECCHHHH
RALAEAISDHGVKSVIHFAGLIEVGRSVAQPDIFWEINVGGTVSLLTAMRERGVERLVFS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHC
SSAAVYGQGGRGPLETIPESAGKAPASPYGDTKLACEWMIEAQCRAYGLTAVALRYFNAA
CCCEEEECCCCCHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GADPSGRIGEAHEPETHLLPLAIAAGLGEGKPLTVFGEDFDTPDGTCLRDYIHVNDLAAA
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
HVAALEVDLPAGAYEAVNVGTGQGHSVREVVEAVGRALGRPVPHSIGARRAGDPPSLVAD
HHHEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHH
ASRARDLLGWEPVCSTLDRIVADALRWEAQPAYGSGRRAGGRKAETAS
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]