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The map label for this gene is irgA [H]

Identifier: 197105484

GI number: 197105484

Start: 2262225

End: 2264597

Strand: Reverse

Name: irgA [H]

Synonym: PHZ_c2021

Alternate gene names: 197105484

Gene position: 2264597-2262225 (Counterclockwise)

Preceding gene: 197105487

Following gene: 197105483

Centisome position: 56.67

GC content: 68.86

Gene sequence:

>2373_bases
ATGACCGAACTGAAGTGGGCGGCGTCGACCGCCGTCATCGCGGCGCTTGCGTGCGCCGGGCCGGCCCTGGCGCAGGAAAC
CGGCGGCGCCACCGTCGAAGCCATCATCGTCACGGCGCAGAAGCGGGAGCAGAACCTCCAGGACGTGCCGATCGTGGTCA
ACGTGGTGTCCGGCCAGCAGCTGCAGGACGCGGGCGTCCGCGACGTGAAGGACCTGCAGGTCCTGACGCCCGGCCTGTCC
GTCACCTCGTCTACGGGCGGCGCCCAGACCTCCATCCGCATCCGCGGCGTCGGCACCATCGGCGACAACCCCGGCCTGGA
ATCCTCGGTCGGCACCGTGATCGACGGCGTCTACCGCGCCCGCTCCGGCGTCGCGTTCGGCGACCTGGGCGAGCTTGAGC
GCATCGAGGTGCTGAAGGGGCCGCAGGGCACCGTGTTCGGCAAGAACACCTCGGCCGGCGTCATCAACGTCATCACCAAG
GCTCCCGAGTTCGATTTTGGCGCCGACGCCGAATTCGTCGCCGGCAACTACGACCACCTGGCGGCCTCGGCCTCGGTCAC
CGGCCCGATCACCGACACCCTGGCCGGCCGCATCTTCGCCGCCCGCCGGGTCCGCGACGGTTTCTACGACGTGCGCAACG
GCGAGGGGCCCTCGACCCAGAAGGACAACGACGACCAGGACGTCTCGACCGTCCGCGGCCAGCTCCTGTGGCTGCCCACC
GACGCGCTCTCGCTGCGCTTCCTCGCCGACTACACCAAGCGCGAGGAGCACTGCTGCCTGAACACCATCACGGTCCCGGG
GCCGACCGCGCCGATCGTCGATGCGCTGGCGACCGACGAGGGCCTGATGCGCCCGGCCGATCCCTTCCGGCGGATCGCCT
ACGCCAACCGCGAGTCCAATCAGGACATCGAGGACATGGGCGTCTCGCTGCAGATCGACTGGGACATGTCGGACGAGGTC
ACGGTCACCTCGATCACCGCCTGGCGCGACTGGGAGAACTTCCAGGCCAACGACATCGACTTCTCGTCGGCCGACATCTG
GTACCGGCCCGACGACGGGCGCACGTTCTCCAAGTTCGAGACCTTCTCCCAGGAACTGCGGGTCGCCGGCCGGTCCGGGC
CGCTCGACTGGATGATCGGCGGCTACTACTCGGACGAGCAGCTCGACTCGAGCGCCTTCACCGCCTTCGGCCTCGACTAC
GAGACCTACTTCGGCCTGCTGCTGTCGGGCGGCGCCAGCCCGACCGCGGTCTCGTCCCTGACGGGCCTGCCGTTCGGCAC
GAACTTCATCCCGGGCCAGGGCTCGTACGACACCTACGACCACAGCAACACCGGCTGGGCGATCTTCACCAACAACACCT
GGCACGTCACCGACGCGCTCGAGGTGACGTTCGGCCTGCGCTACACCGACGACACCAAGAAGGTCTTCTCGCAGTACCGT
AACACCGCGCCGGGGAACGCCTGCGCCGCGGCTATCGCCCGGCCGATCCCGGCGGCCGCCCGCGCCGCCATCTGCGCGCC
CACGGGCGATCCGGCGTTCAACAACGTCGACACCCGCCAGAAGCGCACCGAGGACCGCCTCGGCGGCACGGTGAAGGTCA
GCTACCGGCTCAGCCCCGAGCTGATGACCTACGTCTCGTACGCCAGCAGCCACAAGAGCGGCGGCTTCAACCTGGACCGC
GCCCGCTTCGCGCCGGGCCAGATCAACACCGACACCAGCTTCCCGGCCGAGACGGTCGAGAGCTACGAGGCGGGCTTCAA
GAGCAACCTGGCCGGCAACAGCCTGATGCTCAACGCGGCGGCCTTCGACCAGACGTTCAAGCACTTCCAGCTCAACACCT
ACACCGGCATCAGCTTCGTGGTCGCCTCGGTGCCGAAGGTGACCTCCAAGGGCGTCGACCTCGACCTCGTCTACCGCACG
CCGTTCGAGGGGCTGACGCTGACCGGCGGCGTCACCTACGCGGTGACCCAGTTCGGCGACTTCGTCCCGGGCCCGGGGAT
CGGGCCGCGCCTGCCGACCTCGCGGGTGTCCTACGCCCCGCTGTGGTCGGCCTCGTGGTCGGCGGCCTACGAGAAGCCGC
TCGGCCAGGACTTCAAGCTGCGGGCCAGCCTCTCGGGCCGCTACACCTCGTCCTACAACACCGGCTCGAACCTCGACCCG
CTGAAGCGCCAGCGGCCGATGACCATCTGGAACGGCCGTATCGGCATCGGCCCCGAGGACGAACGCTGGATGCTGGAGGC
CTGGGCCCAGAACCTGACCGACGTGAACTACTACCAGGTGGTGGTCGACCAGCCGCTGCAGTCGGGCACCTTCGCCGCCT
TCCTCGGTTCGCCGCGGACCGTCGGGGCGACGCTGCGGGTGAAGTTCAACTAA

Upstream 100 bases:

>100_bases
GATAGCTTGTTCGCTCGCGCCGCCCTCCGCAAGCTCCGTCGACGGACCCGGCTCCAGCCGGGCCGAAACTAGCCGCCTGA
AGAGCGGCGCGGGAGGGATA

Downstream 100 bases:

>100_bases
GCCGATGGACCTGGACCTCACCCCGGAGGATCTCGCCTTCCGAGACGAGGTCCGGGCCTTTCTCGCCGCGGAGCTCACGC
CCGAGCTTCGCGAGGCGGGG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MTELKWAASTAVIAALACAGPALAQETGGATVEAIIVTAQKREQNLQDVPIVVNVVSGQQLQDAGVRDVKDLQVLTPGLS
VTSSTGGAQTSIRIRGVGTIGDNPGLESSVGTVIDGVYRARSGVAFGDLGELERIEVLKGPQGTVFGKNTSAGVINVITK
APEFDFGADAEFVAGNYDHLAASASVTGPITDTLAGRIFAARRVRDGFYDVRNGEGPSTQKDNDDQDVSTVRGQLLWLPT
DALSLRFLADYTKREEHCCLNTITVPGPTAPIVDALATDEGLMRPADPFRRIAYANRESNQDIEDMGVSLQIDWDMSDEV
TVTSITAWRDWENFQANDIDFSSADIWYRPDDGRTFSKFETFSQELRVAGRSGPLDWMIGGYYSDEQLDSSAFTAFGLDY
ETYFGLLLSGGASPTAVSSLTGLPFGTNFIPGQGSYDTYDHSNTGWAIFTNNTWHVTDALEVTFGLRYTDDTKKVFSQYR
NTAPGNACAAAIARPIPAAARAAICAPTGDPAFNNVDTRQKRTEDRLGGTVKVSYRLSPELMTYVSYASSHKSGGFNLDR
ARFAPGQINTDTSFPAETVESYEAGFKSNLAGNSLMLNAAAFDQTFKHFQLNTYTGISFVVASVPKVTSKGVDLDLVYRT
PFEGLTLTGGVTYAVTQFGDFVPGPGIGPRLPTSRVSYAPLWSASWSAAYEKPLGQDFKLRASLSGRYTSSYNTGSNLDP
LKRQRPMTIWNGRIGIGPEDERWMLEAWAQNLTDVNYYQVVVDQPLQSGTFAAFLGSPRTVGATLRVKFN

Sequences:

>Translated_790_residues
MTELKWAASTAVIAALACAGPALAQETGGATVEAIIVTAQKREQNLQDVPIVVNVVSGQQLQDAGVRDVKDLQVLTPGLS
VTSSTGGAQTSIRIRGVGTIGDNPGLESSVGTVIDGVYRARSGVAFGDLGELERIEVLKGPQGTVFGKNTSAGVINVITK
APEFDFGADAEFVAGNYDHLAASASVTGPITDTLAGRIFAARRVRDGFYDVRNGEGPSTQKDNDDQDVSTVRGQLLWLPT
DALSLRFLADYTKREEHCCLNTITVPGPTAPIVDALATDEGLMRPADPFRRIAYANRESNQDIEDMGVSLQIDWDMSDEV
TVTSITAWRDWENFQANDIDFSSADIWYRPDDGRTFSKFETFSQELRVAGRSGPLDWMIGGYYSDEQLDSSAFTAFGLDY
ETYFGLLLSGGASPTAVSSLTGLPFGTNFIPGQGSYDTYDHSNTGWAIFTNNTWHVTDALEVTFGLRYTDDTKKVFSQYR
NTAPGNACAAAIARPIPAAARAAICAPTGDPAFNNVDTRQKRTEDRLGGTVKVSYRLSPELMTYVSYASSHKSGGFNLDR
ARFAPGQINTDTSFPAETVESYEAGFKSNLAGNSLMLNAAAFDQTFKHFQLNTYTGISFVVASVPKVTSKGVDLDLVYRT
PFEGLTLTGGVTYAVTQFGDFVPGPGIGPRLPTSRVSYAPLWSASWSAAYEKPLGQDFKLRASLSGRYTSSYNTGSNLDP
LKRQRPMTIWNGRIGIGPEDERWMLEAWAQNLTDVNYYQVVVDQPLQSGTFAAFLGSPRTVGATLRVKFN
>Mature_789_residues
TELKWAASTAVIAALACAGPALAQETGGATVEAIIVTAQKREQNLQDVPIVVNVVSGQQLQDAGVRDVKDLQVLTPGLSV
TSSTGGAQTSIRIRGVGTIGDNPGLESSVGTVIDGVYRARSGVAFGDLGELERIEVLKGPQGTVFGKNTSAGVINVITKA
PEFDFGADAEFVAGNYDHLAASASVTGPITDTLAGRIFAARRVRDGFYDVRNGEGPSTQKDNDDQDVSTVRGQLLWLPTD
ALSLRFLADYTKREEHCCLNTITVPGPTAPIVDALATDEGLMRPADPFRRIAYANRESNQDIEDMGVSLQIDWDMSDEVT
VTSITAWRDWENFQANDIDFSSADIWYRPDDGRTFSKFETFSQELRVAGRSGPLDWMIGGYYSDEQLDSSAFTAFGLDYE
TYFGLLLSGGASPTAVSSLTGLPFGTNFIPGQGSYDTYDHSNTGWAIFTNNTWHVTDALEVTFGLRYTDDTKKVFSQYRN
TAPGNACAAAIARPIPAAARAAICAPTGDPAFNNVDTRQKRTEDRLGGTVKVSYRLSPELMTYVSYASSHKSGGFNLDRA
RFAPGQINTDTSFPAETVESYEAGFKSNLAGNSLMLNAAAFDQTFKHFQLNTYTGISFVVASVPKVTSKGVDLDLVYRTP
FEGLTLTGGVTYAVTQFGDFVPGPGIGPRLPTSRVSYAPLWSASWSAAYEKPLGQDFKLRASLSGRYTSSYNTGSNLDPL
KRQRPMTIWNGRIGIGPEDERWMLEAWAQNLTDVNYYQVVVDQPLQSGTFAAFLGSPRTVGATLRVKFN

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=150, Percent_Identity=30.6666666666667, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1786798, Length=220, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787024, Length=640, Percent_Identity=23.125, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 85431; Mature: 85300

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELKWAASTAVIAALACAGPALAQETGGATVEAIIVTAQKREQNLQDVPIVVNVVSGQQ
CCCCCHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEEEHHHHCCCCCCCEEEEEECCCC
LQDAGVRDVKDLQVLTPGLSVTSSTGGAQTSIRIRGVGTIGDNPGLESSVGTVIDGVYRA
HHHCCCCCCCHHEEECCCCEEECCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHH
RSGVAFGDLGELERIEVLKGPQGTVFGKNTSAGVINVITKAPEFDFGADAEFVAGNYDHL
HCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCCCEECCCCHHH
AASASVTGPITDTLAGRIFAARRVRDGFYDVRNGEGPSTQKDNDDQDVSTVRGQLLWLPT
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECC
DALSLRFLADYTKREEHCCLNTITVPGPTAPIVDALATDEGLMRPADPFRRIAYANRESN
HHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCC
QDIEDMGVSLQIDWDMSDEVTVTSITAWRDWENFQANDIDFSSADIWYRPDDGRTFSKFE
CCHHHCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCHHHHH
TFSQELRVAGRSGPLDWMIGGYYSDEQLDSSAFTAFGLDYETYFGLLLSGGASPTAVSSL
HHHHHHHHCCCCCCCCEEECCEECCCCCCCCCEEEECCCHHHHHHHHEECCCCCHHHHHH
TGLPFGTNFIPGQGSYDTYDHSNTGWAIFTNNTWHVTDALEVTFGLRYTDDTKKVFSQYR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEEEEEEEEECCHHHHHHHHHH
NTAPGNACAAAIARPIPAAARAAICAPTGDPAFNNVDTRQKRTEDRLGGTVKVSYRLSPE
CCCCCHHHHHHHHCCCCHHHCEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECHH
LMTYVSYASSHKSGGFNLDRARFAPGQINTDTSFPAETVESYEAGFKSNLAGNSLMLNAA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCEEEEEHH
AFDQTFKHFQLNTYTGISFVVASVPKVTSKGVDLDLVYRTPFEGLTLTGGVTYAVTQFGD
HHHHHHHHEEEECCCCHHHHHHCCCCHHCCCCCEEEEEECCCCCEEEECCCEEEEEHHCC
FVPGPGIGPRLPTSRVSYAPLWSASWSAAYEKPLGQDFKLRASLSGRYTSSYNTGSNLDP
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCCEECCCCCCCCCCH
LKRQRPMTIWNGRIGIGPEDERWMLEAWAQNLTDVNYYQVVVDQPLQSGTFAAFLGSPRT
HHHCCCCEEECCEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCCCCE
VGATLRVKFN
ECEEEEEEEC
>Mature Secondary Structure 
TELKWAASTAVIAALACAGPALAQETGGATVEAIIVTAQKREQNLQDVPIVVNVVSGQQ
CCCCHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEEEHHHHCCCCCCCEEEEEECCCC
LQDAGVRDVKDLQVLTPGLSVTSSTGGAQTSIRIRGVGTIGDNPGLESSVGTVIDGVYRA
HHHCCCCCCCHHEEECCCCEEECCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHH
RSGVAFGDLGELERIEVLKGPQGTVFGKNTSAGVINVITKAPEFDFGADAEFVAGNYDHL
HCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCCCEECCCCHHH
AASASVTGPITDTLAGRIFAARRVRDGFYDVRNGEGPSTQKDNDDQDVSTVRGQLLWLPT
EECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECC
DALSLRFLADYTKREEHCCLNTITVPGPTAPIVDALATDEGLMRPADPFRRIAYANRESN
HHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCC
QDIEDMGVSLQIDWDMSDEVTVTSITAWRDWENFQANDIDFSSADIWYRPDDGRTFSKFE
CCHHHCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCHHHHH
TFSQELRVAGRSGPLDWMIGGYYSDEQLDSSAFTAFGLDYETYFGLLLSGGASPTAVSSL
HHHHHHHHCCCCCCCCEEECCEECCCCCCCCCEEEECCCHHHHHHHHEECCCCCHHHHHH
TGLPFGTNFIPGQGSYDTYDHSNTGWAIFTNNTWHVTDALEVTFGLRYTDDTKKVFSQYR
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEEEEEEEEECCHHHHHHHHHH
NTAPGNACAAAIARPIPAAARAAICAPTGDPAFNNVDTRQKRTEDRLGGTVKVSYRLSPE
CCCCCHHHHHHHHCCCCHHHCEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECHH
LMTYVSYASSHKSGGFNLDRARFAPGQINTDTSFPAETVESYEAGFKSNLAGNSLMLNAA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCEEEEEHH
AFDQTFKHFQLNTYTGISFVVASVPKVTSKGVDLDLVYRTPFEGLTLTGGVTYAVTQFGD
HHHHHHHHEEEECCCCHHHHHHCCCCHHCCCCCEEEEEECCCCCEEEECCCEEEEEHHCC
FVPGPGIGPRLPTSRVSYAPLWSASWSAAYEKPLGQDFKLRASLSGRYTSSYNTGSNLDP
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCCEECCCCCCCCCCH
LKRQRPMTIWNGRIGIGPEDERWMLEAWAQNLTDVNYYQVVVDQPLQSGTFAAFLGSPRT
HHHCCCCEEECCEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCCCCE
VGATLRVKFN
ECEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]